Abstract: A method and apparatus that deterioration of the flow state of a coal/kerosene slurry while preventing the damage caused by overloading to thereby achieve excellent solid-liquid separation performance. In a solid-liquid separation supplying a dehydrated coal/kerosene slurry to a decanter-type centrifugal separator to separate the coal/kerosene slurry into a solid fraction and a liquid fraction, an opening degree target value is determined on the basis of the difference between a target value and an actually measured value of a torque that acts on a screw conveyor of the decanter-type centrifugal separator, and the opening degree of a flow volume control valve, which is arranged in the middle of a supply line for supplying the coal/kerosene slurry into the decanter-type centrifugal separator, is adjusted to the opening degree target value.

Abstract: According to one embodiment, a semiconductor device includes a substrate, a stacked body, and a columnar portion. The stacked body, provided on the substrate, includes first conductive layers and first insulating layers provided alternately along a first direction. The columnar portion extends through the stacked body in the first direction. The columnar portion includes a blocking layer, a charge storage layer, a tunneling layer, and a semiconductor layer. The columnar portion includes a first portion and a second portion. The second portion is provided on the substrate side of the first portion. A dimension in the second direction of the second portion is smaller than a dimension in a second direction of the first portion. A portion of the blocking layer is provided at the second portion being thicker than a portion of the blocking layer provided at the first portion.

Abstract: A semiconductor memory device includes a stacked body in which electrode films and insulating films are stacked alternately along a first direction, a semiconductor member extending in the first direction, and a charge storage member provided between the semiconductor member and the electrode film. The electrode film includes a first conductive layer and a second conductive layer. The first conductive layer is provided on an upper surface of the insulating film and on a lower surface of the insulating film. The second conductive layer is provided between the first conductive layer in a first portion of the electrode film. Thickness of the first conductive layer in the first portion is thinner than thickness of the first conductive layer in a second portion of the electrode film. The second portion is placed between the first portion and the semiconductor member.

Abstract: The present invention provides a graft more suitable for the transplantation of corneal endothelial cells and an application method thereof. Specifically, the present invention provides a corneal endothelial preparation capable of cell proliferation in vivo, which contains a substrate and a corneal endothelial cell layer cultured on the substrate, and a treatment method of a disease selected from the group consisting of bullous keratopathy, corneal edema, corneal leukoma and corneal endothelial inflammation, which includes a step of transplanting the preparation to patients. As the substrate, collagen is used.

Abstract: A method for producing an ashless coal which includes a slurry preparation step, an extraction step, a separation step, an ashless coal acquirement step, and a by-product acquirement step. The separation step is conducted under the state of being pressurized to a pressure equal to or higher than a vapor pressure of the solvent. In the by-product acquirement step, the solvent is evaporated and separated from the solid content-concentrated slurry by spraying the solid content-concentrated slurry into a flash tank in which a pressure is set to lower than a saturation pressure of the solid content-concentrated slurry from a spray nozzle while maintaining a pressure of the solid content-concentrated slurry in a nozzle orifice of the spray nozzle at a level equal to or higher than the vapor pressure of the solvent.

Abstract: A production apparatus of an ashless coal includes a preheater, an extraction tank, a feed pipe, a solid-liquid separator and a solvent separator. The preheater heats a solvent. The extraction tank extracts a coal component soluble in the solvent from a slurry including a mixture of a coal and the solvent heated by the preheater. The coal feeding unit feeds the coal to the feed pipe by pressuring a feed part to the feed pipe such that the solvent does not flow back. The solid-liquid separator separates a solution part containing the coal component from the slurry. The solvent separator evaporates and separates the solvent from the solution part to obtain an ashless coal.

Abstract: A semiconductor device includes first and second memory cells, a first word line, and a first and second bit lines, and a row control circuit. The first memory cell has a first gate electrode and a first channel having one end and another end. The second memory cell has a second gate electrode and a second channel having one end and another end. The first word line electrically connected with each of the first gate electrode and the second gate electrode. The first and second bit lines electrically connected with the first and second channels, respectively. When a threshold voltage of each of the first and second memory cells are caused to be shifted, the semiconductor device causes a first voltage between the first gate electrode and the first channel and a second voltage between the second gate electrode and the second channel to be differentiated.

Abstract: A method for producing an ash-free coal includes a step of mixing a coal with a solvent to prepare a slurry; a step of dissolving away a coal component soluble in the solvent, from the coal, by heating the slurry; a step of separating the solution containing the coal component dissolved therein from the slurry after the dissolution; and a step of subjecting the solution separated in the separation step to a vaporization and a separation of the solvent to obtain an ash-free coal. The separation step and the dissolution step are simultaneously performed.

Abstract: According to one embodiment, a semiconductor memory device includes a stacked body, first memory portions, and second memory portions. The stacked body includes conductive layers. The conductive layers are arranged in a first direction and extend in a second direction. The stacked body includes first and second regions. The second region is arranged with the first region in the second direction. The first memory portions extend in the first direction through the first region and are arranged at a first pitch along the second direction. The second memory portions extend in the first direction through the second region and are arranged at the first pitch along the second direction. A distance between a first center of one of the first memory portions and a second center of one of the second memory portions is longer than the first pitch and shorter than 2 times the first pitch.

Abstract: To provide a method for producing a solid fuel that can efficiently evaporate moisture contained in a slurry by enhancing heat exchange efficiency. The method for producing a solid fuel of the present invention includes the steps of: preparing a slurry by mixing powdery low-grade coal and oil; evaporating moisture contained in the slurry by heating; and separating the slurry obtained after the evaporation step into solid and liquid, wherein the evaporation step includes the steps of: preheating the slurry in a first circulation route; and heating the preheated slurry in a second circulation route that is different from the first circulation route. Preferably, in the preheating step and the heating step, a multitubular heat exchanger is used, the heating medium is supplied to the shell side, and the slurry is supplied to the tube side.

Abstract: The present invention provides a technique for treating retinal epithelium and/or nerves. More specifically, the present invention is an agent for the treatment or prevention of retinal disease or the like and/or a disease, disorder, or ophthalmological state of the nerves, the agent including at least one factor selected from the group consisting of laminin and fragments thereof, wherein the problem is solved by also providing a technique characterized in that this agent is administered together with retinal pigment epithelial cells and/or nerve cells. Specifically, the present invention can include laminin 411 (?4?1?1), laminin 511 (?5?1?1), laminin 521 (?5?2?1), or fragments of these.

Abstract: The present invention provides a technique for treating the cornea. More specifically, the present invention is an agent for the treatment or prevention of a state of corneal endothelial disease, the agent including at least one factor selected from the group consisting of laminin and fragments thereof, wherein the problem is solved by also providing a technique characterized in that this agent is administered together with corneal endothelial cells. Specifically, the present invention can include laminin 511 (?5?1?1), laminin 521 (?5?2?1), or a fragment of these.

Abstract: The present invention is provided with a step for preheating coal, a step for heating an extraction solvent, a step for mixing the preheated coal and the extraction solvent heated to a higher temperature than the preheated coal and thereby heating the coal, a step for separating a solution in which a coal component is dissolved from the mixture of the coal and the extraction solvent, and a step for evaporating and separating the extraction solvent from the solution.

Abstract: A method for producing an ashless coal includes an extraction step, a separation step and an ashless coal acquirement step. In the extraction step, a slurry obtained by mixing a coal with a solvent is heated and thereby a solvent-soluble component of the coal is extracted. In the separation step, the slurry is separated into a solution of the solvent-soluble component of the coal and a solid content-concentrated liquid. In the ashless coal acquirement step, an ashless coal is obtained by evaporating and separating the solvent from the solution. The solvent is a mixture of a dissolution medium and a coal extraction accelerator added thereto. The solvent contains a bicyclic aromatic compound that is liquid at ordinary temperature. The coal extraction accelerator containing no nitrogen has two benzene rings and has at least one cyclic structure having no double bond.

Abstract: A method for producing an ashless coal includes a slurry preparation, an extraction, a separation, an ashless coal acquirement, and a by-product acquirement. In the by-product acquirement, a solvent used in the slurry preparation is evaporated and separated from a solid-content concentrated liquid separated in the separation, and then, a by-product coal is acquired. The by-product coal is used as a fuel for heating a slurry obtained in the slurry preparation.

Abstract: The present invention relates to a differentiation marker and a differentiation controlling technique for an eye cell. More particularly, the present invention has attained an object of providing a differentiation marker for an eye cell among the aforementioned problems, by providing a marker for identifying a cell having a high proliferation ability among corneal endothelial cells and/or the differentiation ability of a corneal endothelial cell, the marker comprising GPR49/LGR5, as well as a detection agent or detection method for identifying a cell having a high proliferation ability among corneal endothelial cells and/or the differentiation ability of a corneal endothelial cell, comprising a substance binding to GPR49/LGR5. In addition, the present invention has attained an object of providing a differentiation controlling technique for an eye cell, by providing an agent for suppressing differentiation and/or promoting proliferation of an eye cell, comprising R-spondins.

Abstract: According to one embodiment, a nonvolatile semiconductor memory device includes memory cell units, bit lines, word lines, and a controller. Each of the memory cell units includes a plurality of memory cells connected in series. Bit lines are connected respectively to the corresponding memory cell units. Each of the word lines is commonly connected to control gates of the corresponding memory cells of the memory cell units. The controller is configured to control a programming operation of data to the memory cells. The controller is configured to execute a first procedure including programming the data to the memory cell connected to the (4n?3)th (n being a natural number) bit line and the memory cell connected to the (4n?2)th bit line, and a second procedure including programming the data to the memory cell connected to the (4n?1)th bit line and the memory cell connected to the 4nth bit line.

Abstract: The purpose of the present invention is to provide an indirect heat drying method and a refined-coal production method, with which the stability of carrier-gas pressure balance can be improved when using indirect heat dryers to dry particulate matter. This indirect heat drying method for particulate matter uses two indirect heat dryers, and is provided with: a step (A) in which particulate matter is dried in a first indirect heat dryer; and a step (B) in which the particulate matter is further dried in a second indirect heat dryer to obtain dried particulate matter.

Abstract: The present invention relates to a differentiation marker and a differentiation controlling technique for an eye cell. More particularly, the present invention has attained an object of providing a differentiation marker for an eye cell among the aforementioned problems, by providing a marker for identifying a cell having a high proliferation ability among corneal endothelial cells and/or the differentiation ability of a corneal endothelial cell, the marker comprising GPR49/LGR5, as well as a detection agent or detection method for identifying a cell having a high proliferation ability among corneal endothelial cells and/or the differentiation ability of a corneal endothelial cell, comprising a substance binding to GPR49/LGR5. In addition, the present invention has attained an object of providing a differentiation controlling technique for an eye cell, by providing an agent for suppressing differentiation and/or promoting proliferation of an eye cell, comprising R-spondins.

Abstract: The present invention provides a method of culturing corneal endothelial cells. More specifically, the present invention provides a composition for culturing or growing corneal endothelial cells, comprising at least one agent consisting of laminins and fragments thereof which express in corneal endothelial cells. Specifically, the present invention can comprise laminin 511 (alpha5 beta1 gamma1) and laminin 512 (alpha5 beta2 gamma 1). The present invention further provides a culture container for corneal endothelial cells, which is coated with the composition of the present invention. Furthermore, the present invention provides a method for culturing corneal endothelial cells comprising the step of using the composition or the container of the present invention to culture the corneal endothelial cells.