Abstract: A handheld surgical endoscope has a disposable, single-use portion that includes a fluid hub and cannula, and a re-usable portion that includes a handle and display module. The distal tip includes LED illumination and an imaging module that feeds live video to the display module. The single-use and re-usable portions mate and un-mate with each other via physically separated mechanical and electrical connectors. The surgical endoscope is configured for operation by a single clinician in many procedures.

Abstract: A method and system acquiring, processing and displaying breast ultrasound images in a way that makes breast ultrasound screening more practical and thus more widely used, and reduces the occurrence of missing cancers in screening and diagnosis, using automated scanning of chestwardly compressed breasts with ultrasound. Enhanced, whole-breast navigator overview images are produced from scanning breasts with ultrasound that emphasize abnormalities in the breast while excluding obscuring influences of non-breast structures, particularly those external to the breast such as ribs and chest wall, and differentiating between likely malignant and likely benign abnormalities and otherwise enhancing the navigator overview image and other images, thereby reducing the time to read, screen, and/or diagnose to practical time limits and also reduce screening or diagnostic errors.

Abstract: A method and system acquiring, processing and displaying breast ultrasound images in a way that makes breast ultrasound screening more practical and thus more widely used, and reduces the occurrence of missing cancers in screening and diagnosis, using automated scanning of chestwardly compressed breasts with ultrasound. Enhanced, whole-breast navigator overview images are produced from scanning breasts with ultrasound that emphasize abnormalities in the breast while excluding obscuring influences of non-breast structures, particularly those external to the breast such as ribs and chest wall, and differentiating between likely malignant and likely benign abnormalities and otherwise enhancing the navigator overview image and other images, thereby reducing the time to read, screen, and/or diagnose to practical time limits and also reduce screening or diagnostic errors.

Abstract: Lateral and vertical microstructure enhanced photodetectors and avalanche photodetectors are monolithically integrated with CMOS/BiCMOS ASICs and can also be integrated with laser devices using fluidic assembly techniques. Photodetectors can be configured in a vertical PIN arrangement or lateral metal-semiconductor-metal arrangement where electrodes are in an inter-digitated pattern. Microstructures, such as holes and protrusions, can improve quantum efficiency in silicon, germanium and III-V materials and can also reduce avalanche voltages for avalanche photodiodes. Applications include optical communications within and between datacenters, telecommunications, LIDAR, and free space data communication.

Abstract: Resistive RAM (RRAM) devices having increased reliability and related manufacturing methods are described. Greater reliability of RRAM cells over time can be achieved by avoiding direct contact of metal electrodes with the device switching layer. The contact can be avoided by cladding the switching layer in a material such as silicon or using electrodes that may contain metal but have regions that are adjacent the switching layer and lack free metal ions except for possible trace amounts.

Abstract: A handheld surgical endoscope has a disposable, single-use portion that includes a fluid hub and cannula, and a re-usable portion that includes a handle and display module. The distal tip includes LED illumination and an imaging module that feeds live video to the display module. The single-use and re-usable portions mate and un-mate with each other via physically separated mechanical and electrical connectors. The surgical endoscope is configured for operation by a single clinician in many procedures.

Abstract: A method and apparatus for acquisition of volumetric breast images for screening and/or diagnosing breast cancers using a rotary scanning template and transducer.

Abstract: A handheld surgical endoscope has a disposable, single-use portion that includes a fluid hub, cannula, distal tip and an integrated needle and a re-usable portion that includes a handle and display module. The distal tip includes LED illumination and an imaging module that feeds live video to the display module that is rotatable to allow viewing by the operator and others. The single-use and re-usable portions mate and un-mate with each other via physically separated mechanical and electrical connectors. The needle is actuatable to allow for both recessed and extended positions. The needle delivers liquid from a attached syringe that can be attached to the handle to move therewith or only connected to the endoscope by a flexible conduit. The surgical endoscope is configured for operation by a single clinician in many procedures.

Abstract: Resistive RAM (RRAM) devices having increased uniformity and related manufacturing methods are described. Greater uniformity of performance across an entire chip that includes larger numbers of RRAM cells can be achieved by uniformly creating enhanced channels in the switching layers through the use of radiation damage. The radiation, according to various described embodiments, can be in the form of ions, electromagnetic photons, neutral particles, electrons, and ultrasound.

Abstract: Methods and devices are described for performing a combined hysteroscopy and endometrial sampling. Techniques for improving visual images include forward facing fluid ports for clearing tissue debris and LED positioning and design. Manufacturability is improved through separately formed tip and shaft pieces. User interface features are described including user-friendly handle-mounted buttons as well the use of an interactive integrated touch screen display. The handle and display can be mated to a docking station for storage and recharging batteries.

Abstract: A handheld surgical endoscope has a disposable, single-use portion that includes a and a re-usable portion that includes a handle and display module. The distal tip includes LED illumination and an imaging module that feeds live video to the display module. The imaging module includes a lens system of no more than two lenses and provides the imaging module with a field of view greater than 120 degrees, preferably 130 degrees or more, and most preferably 140 degrees or more. LED illumination is provided by plural LED arranged symmetrically around an optical axis to provide a field of illumination that substantially coincides with the field of view of an imaging module. An image brightness balance arrangement selectively varies the illumination provided by different LEDs to reduce brightness differences between different areas of the displayed images.

Abstract: Microstructure enhanced photodiodes and avalanche photodiodes are monolithically integrated with CMOS/BiCMOS circuitry such as transimpedance amplifiers. Microstructures, such as holes, can improve quantum efficiency in silicon and III-V materials and can also reduce avalanche voltages for avalanche photodiodes. Applications include optical communications within and between datacenters, telecommunications, LIDAR, and free space data communication.

Abstract: A handheld endoscope has a disposable, single-use portion that includes a fluid hub, cannula and distal tip and a re-usable portion that includes a handle and display module. The electrical connection between the single-use and reusable portions is distally spaced from their mechanical connection and from the fluid hub. The distal tip includes LED illumination and an imaging module that feeds live video to the display module that is rotatable to allow viewing by the operator and others. The cannula and fluid hub are rotatable relative to the handle and includes separate lumens for fluid flow and an electrical cable. The fit resists rotation to maintain the relative positions of the cannula and handle until the application of a torque threshold. The single-use and re-usable portions mate and un-mate with each other via the physically separated mechanical and electrical connectors. Extruded cannula and molded distal tip parts can be separately formed which aids in manufacturing and assembly.

Abstract: A method and system acquiring, processing and displaying breast ultrasound images in a way that makes breast ultrasound screening more practical and thus more widely used, and reduces the occurrence of missing cancers in screening and diagnosis, using automated scanning of chestwardly compressed breasts with ultrasound. Enhanced, whole-breast navigator overview images are produced from scanning breasts with ultrasound that emphasize abnormalities in the breast while excluding obscuring influences of non-breast structures, particularly those external to the breast such as ribs and chest wall, and differentiating between likely malignant and likely benign abnormalities and otherwise enhancing the navigator overview image and other images, thereby reducing the time to read, screen, and/or diagnose to practical time limits and also reduce screening or diagnostic errors.

Abstract: An adjunctive ultrasound mammography system and associated methods use an adjunctive ultrasound display configured for quick, intuitive, interactive viewing of volumetric ultrasound scans, displayed near a conventional x-ray mammogram display. Preferred navigations among a thick-slice image array, a selected enlarged thick-slice image, and planar ultrasound views are described, including a mode in which the planar ultrasound views are updated in real time as a cursor is moved across an active thick-slice image. In one example the thick-slice images are inverted prior to display, with non-breast areas of the image preferably segmented out and reset to dark. The inverted thick-slice images are of more familiar significance to radiologists as they are more like conventional x-ray mammograms and allow benign features to be more easily dismissed as compared to non-inverted thick-slice images.

Abstract: A method and system for processing and displaying breast ultrasound information is described. A 2D feature weighted volumetric coronal image as a “guide” or “road map” is generated from the 3D ultrasound data volume to represent the 3D dataset with the goal of emphasizing abnormalities within the breast while excluding non-breast structures, particularly those external to the breast such as ribs and chest wall.

Abstract: Techniques for enhancing the absorption of photons in semiconductors with the use of microstructures are described. The microstructures, such as holes, effectively increase the absorption of the photons. Using microstructures for absorption enhancement for silicon photodiodes and silicon avalanche photodiodes can result in bandwidths in excess of 10 Gb/s at photons with wavelengths of 850 nm, and with quantum efficiencies of approximately 90% or more. Their thickness dimensions allow them to be conveniently integrated on the same Si chip with CMOS, BiCMOS, and other electronics, with resulting packaging benefits and reduced capacitance and thus higher speeds.

Abstract: Resistive RAM (RRAM) devices having increased uniformity and related manufacturing methods are described. Greater uniformity of performance across an entire chip that includes larger numbers of RRAM cells can be achieved by uniformly creating enhanced channels in the switching layers through the use of radiation damage. The radiation, according to various described embodiments, can be in the form of ions, electromagnetic photons, neutral particles, electrons, and ultrasound.

Abstract: A handheld endoscope has a disposable, single-use portion that includes a fluid hub, cannula and distal tip and a re-usable portion that includes a handle and display module. The electrical connection between the single-use and reusable portions is distally spaced from their mechanical connection and from the fluid hub. The distal tip includes LED illumination and an imaging module that feeds live video to the display module that is rotatable to allow viewing by the operator and others. The cannula and fluid hub are rotatable relative to the handle and includes separate lumens for fluid flow and an electrical cable. The fit resists rotation to maintain the relative positions of the cannula and handle until the application of a torque threshold. The single-use and re-usable portions mate and un-mate with each other via the physically separated mechanical and electrical connectors. Extruded cannula and molded distal tip parts can be separately formed which aids in manufacturing and assembly.

Abstract: Instalments and methods are described for performing endoscopically guided operative procedures. According to some embodiments, a re-usable portion of the instrument includes a handle, electronics and an integrated display screen while a fluid hub and a cannula which includes a CMOS imaging module and LED lighting, form a single use portion of the instrument. The cannula includes a working channel configured to accept an operative device for performing the operative procedures.