Abstract: The present invention provides a multifunctional measuring device capable of determining carotid blood pressure, comprising: a heartbeat sensing unit to be disposed on a subject's chest in order to obtain heartbeat signals; a pulse sensing unit to be disposed on the subject's neck at a position corresponding to the subject's carotid arteries in order to obtain pulse signals; and a data calculation unit configured to communicate with the heartbeat sensing unit and the pulse sensing unit and to process signals coming from the heartbeat sensing unit and from the pulse sensing unit; wherein the data calculation unit obtains a mean arterial pressure of the subject's carotid arteries by calculating with the heartbeat signals coming from the heartbeat sensing unit and the pulse signals coming from the pulse sensing unit.

Abstract: The present invention provides a carotid blood pressure detection device, comprising: a first sensing unit, a second sensing unit, and a controller connected or coupled to the first sensing unit and the second sensing unit. The first sensing unit is disposed on a subject's neck and adjacent to a first position of the subject's carotid arteries. The second sensing unit is disposed on the subject's neck and adjacent to a second position of the subject's carotid arteries. The controller derives a mean arterial pressure of a section of the subject's carotid arteries that lies between the first position and the second position of the subject's carotid arteries from pulse wave data measured and obtained by the first sensing unit and pulse wave data measured and obtained by the second sensing unit.

Abstract: The present invention provides a carotid physiological parameter monitoring system, comprising: an electrocardiographic (ECG) monitoring device, a carotid pulse wave detector, and at least one controller. The ECG monitoring device is disposed on a user's left and right wrists or on the user's chest to obtain ECG waveforms. The carotid pulse wave detector is disposed on the user's neck at a position corresponding to the user's carotid arteries for obtaining carotid pulse waveforms. The controller is provided in at least one of the ECG monitoring device, the carotid pulse wave detector, and a mobile device, wherein the controller is configured to obtain the user's carotid physiological parameter(s) (which may include carotid pulse wave velocity or carotid blood pressure) by calculating with the ECG waveforms and/or the carotid pulse waveforms.

Abstract: The present invention provides a wearable device capable of blood pressure measurement, comprising a wrist band assembly, a display unit provided on the wrist band assembly, and a detachable bladder provided on a backside of the wrist band assembly, wherein the wrist band assembly is provided with a micro air pump connected to the detachable bladder, an air pressure sensor provided on a side of the detachable bladder, and a processor connected to the micro air pump and the air pressure sensor, and the processor activates the micro air pump according to a trigger signal in order for the micro air pump to inflate the detachable bladder and for a user's blood pressure parameters to be derived from data sent by the air pressure sensor to the processor.

Abstract: A method for detecting heart rhythm irregularities, including the steps of: measuring pulse peaks continuously over a period of time to obtain pulse peak sequence and pulse peak time interval sequence corresponding to the pulse peak sequence; and calculating the absolute value of a difference between a single pulse peak time interval in the pulse peak time interval sequence and an average value of the pulse peak time interval sequence, and determining that an irregular pulse peak (IPP) has occurred if the absolute value is larger than or equal to 15% to 25% of the average value of the pulse peak time interval sequence. A detection device using the method is also provided. This uses a non-invasive approach to detect heart rhythm irregularities such as sick sinus syndrome, irregular pulse peaks, irregular heartbeat, and atrial fibrillation, and can be applied to a sphygmomanometer or a wearable device.

Abstract: A single-arm micro air-pressure pump device, having an air pump body and a driving unit. The air pump body includes a supporting frame, an air chamber unit coupled to a side of the supporting frame, and a swing arm provided on the air chamber unit. The driving unit is fixed on the supporting frame and has an output shaft. The output shaft is provided with an eccentric shaft and is configured to rotate the eccentric shaft, and the eccentric shaft has an end coupled to the output shaft and an opposite end coupled to the swing arm in order to drive the swing arm into a reciprocating motion between at least a proximal position and a distal position with respect to the air chamber unit. The reciprocating motion pushes a piston unit provided on one end of the swing arm and causes the air output.

Abstract: The present invention provides a pulse detection module and a use-as-you-need blood pressure measurement device comprising the pulse detection module. The pulse detection module is characterized by comprising a plurality of sensors and a controller linked to the sensors, wherein the sensors are arranged horizontally on the wrist watch in a direction parallel to a user's limb on which the wrist watch is worn, and the controller obtains the user's pulse signals through the sensors.

Abstract: The present invention provides a dynamic measurement device with a blood pressure determination function, comprising: a heartbeat sensing module disposed on the chest area of a user wherein the heartbeat sensing module comprising a heart sound sensor for obtaining heartbeat signals; a pulse sensing module disposed on a limb area of the user, the pulse sensing module comprising a pulse wave sensor for obtaining pulse signals; and a data calculating module for calculating a mean arterial pressure and a value of systolic blood pressure and diastolic blood pressure based on the heartbeat signals and pulse signals. In addition to dynamically monitoring the blood pressure of a user for 24 hours, the present invention can dynamically monitor the heart sounds of the user for 24 hours individually in order to monitor user's physical condition. Therefore, the present invention has important medical meanings.

Abstract: The present invention provides an electrocardiographic monitoring device comprising a device body configured to be attached to a user's chest; a plurality of electrodes provided on the device body; and a controller provided on the device body and connected to the electrodes in order to obtain the user's electrocardiographic signal waveforms. The electrocardiographic monitoring device of the invention can be applied in a blood pressure monitoring system for monitoring a user's blood pressure.

Abstract: Embodiments of the present disclosure set forth a sensor for detecting a target of interest. One example sensor may comprise an apparatus for binding the target of interest and a draining unit for draining fluid from the apparatus. The apparatus may comprise a substrate, a material disposed on the substrate, and a probe disposed on the material and configured to bind to the target of interest. The probe is configured on the material to scatter light emitted from a light source when the target of interest is bound to the probe.

Abstract: Embodiments of the present disclosure set forth a biosensor for detecting a target. One example sensor includes a first electrode. The first electrode includes a first electron conducting molecule and a first probe. The first probe includes a second electron conducting molecule. The first probe is configured to bind to the target of interest in solution. The first and second electron conducting molecules are different.

Abstract: An electro-immuno sensor includes a signal generator, a sensing chip and a sensing circuit. The signal generator is arranged for generating an electronic signal having a predetermined frequency and a waveform. The sensing chip is disposed in an electrical field that generates the electronic signal, and arranged for capturing target biomolecules in a solution using antibodies. The sensing circuit has a first electrode and a second electrode in contact with the solution, and arranged for measuring an electrical characteristic of a first state and the electrical characteristic of a second state between the first and second electrodes, due to the capture of the target biomolecules, and determining the concentration of the target biomolecules according to the variation of the electrical characteristic.

Abstract: Embodiments of the present disclosure set forth a sensor for detecting a target of interest. One example sensor may comprise an apparatus for binding the target of interest and a draining unit for draining fluid from the apparatus. The apparatus may comprise a substrate, a material disposed on the substrate, and a probe disposed on the material and configured to bind to the target of interest. The probe is configured on the material to scatter light emitted from a light source when the target of interest is bound to the probe.

Abstract: Embodiments of the present disclosure set forth a sensor for detecting a target of interest. One exemplary sensor may comprise a container; a probe disposed in the container; a circulation means configured to circulate substances in the container; a light source; a light receiver; and a detector configured to generate an electrical signal, the magnitude of which reflects the amount of light that is received by the light receiver, wherein the sensor is located between the light source and the light receiver, and wherein the sensor is configured such that the probe and the path of the light emitted by the light source are in different regions inside the container.

Abstract: Embodiments of the present disclosure set forth a sensor for detecting a target of interest. One exemplary sensor may comprise a container; a probe disposed in the container and configured to bind to a target of interest; a circulation means configured to circulate substances in the container; a light source; a light receiver; a light selecting unit for allowing light of a predetermined wavelength be received by the light receiver; and a detector configured to generate an electrical signal. The magnitude of the electrical signal reflects the amount of light that is received by the light receiver. The container is located between the light source and the light receiver. Moreover, the container is configured such that the probe and the path of the light emitted by the light source are in different regions inside the container.

Abstract: A sensor comprises a light source that emits light, a light receiver for receiving light, a sampling unit for binding the target of interest disposed between the light source and the light receiver, a light selecting unit for allowing light of a predetermined wavelength be received by the light receiver, and a detector configured to generate an electrical signal, and the magnitude of which reflects the amount of light that is received by the light receiver. The sampling unit comprises a substrate, a material disposed on the substrate, and a probe disposed on the material and configured to bind to the target of interest. The sampling unit is configured such that the probe is in the path of the light emitted by the light source.

Abstract: Embodiments of the present disclosure set forth an apparatus of a sensor for detecting a target of interest. One example apparatus may comprise a substrate, a material disposed on the substrate and a probe disposed on the material. The probe is configured to bind to the target of interest and scatter light emitted from a light source when the target of interest is bound to the probe.

Abstract: A method of fabricating semiconductor devices is disclosed. The method comprises providing a substrate with a plurality of epitaxial layers mounted on the substrate and separating the substrate from the plurality of epitaxial layers while the plurality of epitaxial layers is intact. This preserves the electrical, optical, and mechanical properties of the plurality of epitaxial layers.

Abstract: A system for compensating a thermal effect is provided and includes a substrate structure and a microcantilever. The substrate structure includes a first piezoresistor. The first piezoresistor is buried in the substrate structure and has a first piezoresistance having a first relation to a first variable temperature. The microcantilever has the thermal effect and a second piezoresistance having a second relation to the first variable temperature, wherein the thermal effect is compensated based on the first and the second relations.

Abstract: Embodiments of the present disclosure set forth a biosensor for detecting a target. One example sensor includes a first electrode. The first electrode includes a first electron conducting molecule and a first probe. The first probe includes a second electron conducting molecule. The first probe is configured to bind to the target of interest in solution. The first and second electron conducting molecules are different.