Abstract: A substrate having a main surface on which a plurality of accommodation parts are formed, a wiping member having a shape that follows that of the main surface, and a magnet disposed on the side of the substrate that is opposite from the wiping member. First, the wiping member is moved forward, whereby a hydrophilic liquid containing a plurality of magnetic beads is spread onto the main surface. The magnet is moved forward together with the wiping member while magnetic force is caused to act on the magnetic beads, whereby the magnetic beads and the hydrophilic liquid are accommodated in the accommodation parts. Second, a hydrophobic liquid arranged on the movement-direction rear side of the wiping member is spread onto the main surface due to the movement of the wiping member, whereby the surface of the hydrophilic liquid within the accommodation parts is covered by the hydrophobic liquid.

Abstract: In a magnetic bead recovery method, a magnetic bead (1) is recovered from a storage section (11) containing the magnetic bead (1) and a first hydrophilic liquid (2). The magnetic bead recovery method comprises: a step for bringing a capillary (5) filled with a second hydrophilic liquid (302) in a range including a tip (5a) close to the storage section (11) through a hydrophilic liquid layer (121) and coalescing the second hydrophilic liquid (302) with the first hydrophilic liquid (2) in the storage section (11); and a step for introducing the magnetic bead (1) by a magnetic force into the capillary (5) through the first hydrophilic liquid (2) and the second hydrophilic liquid (302).

Abstract: It is possible to provide a laminated sheet that is applicable to large molded articles, exhibits excellent rigidity, particularly excellent homogeneity of in-plane rigidity when formed into a large area, and has minimal variation in mechanical properties. The laminated sheet of the present invention has a structure in which layer a, comprising a biaxially oriented polypropylene film, and layer b, comprising an olefin-based resin with a melting point of 110 to 160° C., are alternately laminated. When one side direction of the laminated sheet is defined as an x-direction and a direction perpendicular thereto as a y-direction, a tensile modulus of elasticity in the x-direction and a tensile modulus of elasticity in the y-direction at three positions—namely, a center position in the y-direction, and two positions located 200 mm from this center position in the y-direction—are all within a range of 2000 to 5000 MPa.

Abstract: There is provided a method for producing a peptide-nucleic acid complex containing a peptide and a nucleic acid encoding the peptide. The method for producing a peptide-nucleic acid complex includes a step of preparing a nucleic acid to which a transpeptidase N-terminal substrate motif has been added, the nucleic acid containing a first coding sequence encoding a peptide, a second coding sequence encoding a transpeptidase, and a third coding sequence encoding a transpeptidase recognition motif; a step of synthesizing a chimeric protein containing a domain of the peptide, a domain of the transpeptidase, and the transpeptidase recognition motif, from the nucleic acid to which the transpeptidase N-terminal substrate motif has been added, using a cell-free protein synthesis system; and a step of forming the peptide-nucleic acid complex by means of the transpeptidase domain.

Abstract: A polypropylene multilayer sheet comprising: a first biaxially oriented polypropylene layer having a melting point Tmh; and a second biaxially oriented polypropylene layer having a melting point Tml, the first biaxially oriented polypropylene layer and the second biaxially oriented polypropylene layer being alternately laminated, the polypropylene multilayer sheet having a thickness of 0.20 to 3.0 mm, wherein Tmh>Tml, and a total number of layers is 3 to 11.

Abstract: A fundus observation apparatus includes an optical system, two concave mirrors, and a holding member. The optical system is configured to project light from a light source onto a fundus of an eye to be examined, and to receive returning light from the fundus. The two concave mirrors have concave reflective surfaces, respectively, configured to guide the light from the optical system to the fundus, and to guide the returning light to the optical system. The holding member is configured to be capable of holding the two concave mirrors in a state where the concave mirrors are arranged on both sides of the holding member so that the concave mirrors are positioned in a default relative position in a predetermined one-dimensional direction or predetermined two-dimensional directions.

Abstract: A polypropylene multilayer sheet comprising: a first biaxially oriented polypropylene layer having a melting point Tmh; and a second biaxially oriented polypropylene layer having a melting point Tml, the first biaxially oriented polypropylene layer and the second biaxially oriented polypropylene layer being alternately laminated, the polypropylene multilayer sheet having a thickness of 0.20 to 3.0 mm, wherein Tmh>Tml, and a total number of layers is 3 to 11.

Abstract: A polypropylene multilayer sheet includes: a biaxially oriented polypropylene layer F having a melting point TmF; and a biaxially oriented polypropylene layer N having a melting point TmN, the biaxially oriented polypropylene layer N and the biaxially oriented polypropylene layer F being alternately laminated, the polypropylene multilayer sheet having a thickness of 0.15 mm to 3.0 mm, wherein: TmF>TmN, a total number of layers is 3 to 11, the biaxially oriented polypropylene layer F is formed of a resin composition containing: a polypropylene-based resin as a component (A); and an inorganic filler as a component (B), a weight ratio of the component (B)/[the component (A)+the component (B)] is 0.5 to 60 wt %, the biaxially oriented polypropylene layer N is formed of a resin composition containing: a polypropylene-based resin as a component (a); and the component (B) as an optional component, and a weight ratio of the component (B)/[the component (a)+the component (B)] is 0 to 10 wt %.

Abstract: An ophthalmologic apparatus includes: a head unit having an optical system capable of receiving light reflected from a subject's eye; a drive mechanism that movably holds the head unit; an alignment detection unit that detects a position of the subject's eye relative to the head unit; and a control unit that controls the drive mechanism. The drive mechanism includes at least two arms rotatably connected together, at least two first rotation support mechanisms and at least three second rotation support mechanisms which allow the head unit to move, and at least five driving units for driving the rotation support mechanisms. The control unit is capable of controlling the driving units using a measurement result of the alignment measuring unit to align the head unit and the subject's eye with each other.

Abstract: A polypropylene multilayer sheet comprising: a first biaxially oriented polypropylene layer having a melting point Tmh; and a second biaxially oriented polypropylene layer having a melting point Tml, the first biaxially oriented polypropylene layer and the second biaxially oriented polypropylene layer being alternately laminated, the polypropylene multilayer sheet having a thickness of 0.20 to 3.0 mm, wherein Tmh>Tml, and a total number of layers is 3 to 11.

Abstract: A polypropylene multilayer sheet includes: a biaxially oriented polypropylene layer F having a melting point TmF; and a biaxially oriented polypropylene layer N having a melting point TmN, the biaxially oriented polypropylene layer N and the biaxially oriented polypropylene layer F being alternately laminated, the polypropylene multilayer sheet having a thickness of 0.15 mm to 3.0 mm, wherein: TmF>TmN, a total number of layers is 3 to 11, the biaxially oriented polypropylene layer F is formed of a resin composition containing: a polypropylene-based resin as a component (A); and an inorganic filler as a component (B), a weight ratio of the component (B)/[the component (A)+the component (B)] is 0.5 to 60 wt %, the biaxially oriented polypropylene layer N is formed of a resin composition containing: a polypropylene-based resin as a component (a); and the component (B) as an optional component, and a weight ratio of the component (B)/[the component (a)+the component (B)] is 0 to 10 wt %.

Abstract: An ophthalmologic apparatus includes: a head unit having an optical system capable of receiving light reflected from a subject's eye; a drive mechanism that movably holds the head unit; an alignment detection unit that detects a position of the subject's eye relative to the head unit; and a control unit that controls the drive mechanism. The drive mechanism includes at least two arms rotatably connected together, at least two first rotation support mechanisms and at least three second rotation support mechanisms which allow the head unit to move, and at least five driving units for driving the rotation support mechanisms. The control unit is capable of controlling the driving units using a measurement result of the alignment measuring unit to align the head unit and the subject's eye with each other.

Abstract: An ophthalmologic apparatus includes: a head unit having an optical system capable of receiving light reflected from a subject's eye; a drive mechanism that movably holds the head unit; an alignment detection unit that detects a position of the subject's eye relative to the head unit; and a control unit that controls the drive mechanism. The drive mechanism includes at least two arms rotatably connected together, at least two first rotation support mechanisms and at least three second rotation support mechanisms which allow the head unit to move, and at least five driving units for driving the rotation support mechanisms. The control unit is capable of controlling the driving units using a measurement result of the alignment measuring unit to align the head unit and the subject's eye with each other.

Abstract: There is provided a method for producing a peptide-nucleic acid complex containing a peptide and a nucleic acid encoding the peptide. The method for producing a peptide-nucleic acid complex includes a step of preparing a nucleic acid to which a transpeptidase N-terminal substrate motif has been added, the nucleic acid containing a first coding sequence encoding a peptide, a second coding sequence encoding a transpeptidase, and a third coding sequence encoding a transpeptidase recognition motif; a step of synthesizing a chimeric protein containing a domain of the peptide, a domain of the transpeptidase, and the transpeptidase recognition motif, from the nucleic acid to which the transpeptidase N-terminal substrate motif has been added, using a cell-free protein synthesis system; and a step of forming the peptide-nucleic acid complex by means of the transpeptidase domain.

Abstract: An ophthalmologic apparatus includes: a head unit having an optical system capable of receiving light reflected from a subject's eye; a drive mechanism that movably holds the head unit; an alignment detection unit that detects a position of the subject's eye relative to the head unit; and a control unit that controls the drive mechanism. The drive mechanism includes at least two arms rotatably connected together, at least two first rotation support mechanisms and at least three second rotation support mechanisms which allow the head unit to move, and at least five driving units for driving the rotation support mechanisms. The control unit is capable of controlling the driving units using a measurement result of the alignment measuring unit to align the head unit and the subject's eye with each other.

Abstract: There is provided a method of manufacturing a protein array or peptide array suitable for an efficient screening of a functional protein or functional peptide. The method of manufacturing a protein array or peptide array includes the steps of: (a) preparing a nucleic acid immobilized on a solid support and a cell-free synthesis system in a reactor, in which a reactor array includes the reactor having a specific aperture shape and a protein capture molecule or a peptide capture molecule provided on at least a portion of wall surface and bottom surface in the reactor; and (c) synthesizing a protein or peptide from the nucleic acid using the cell-free synthesis system and immobilizing the protein or peptide in the reactor.

Abstract: The present invention relates to a nucleic acid linker for producing a complex of mRNA, and a protein or a peptide which is encoded by the mRNA, the linker comprising: a spacer portion at the 5?-terminal; a polynucleotide portion hybridizable with at least a part of a sequence of the mRNA; and an arm portion which has a connection portion for the protein or the peptide at the 3?-terminal, in which the spacer portion, the polynucleotide portion, and the arm portion form a single strand, and in which the polynucleotide portion contains a photoreactive base derivative.

Abstract: There is provided a method of manufacturing a protein array or peptide array suitable for an efficient screening of a functional protein or functional peptide. The method of manufacturing a protein array or peptide array includes the steps of: (a) preparing a nucleic acid immobilized on a solid support and a cell-free synthesis system in a reactor, in which a reactor array includes the reactor having a specific aperture shape and a protein capture molecule or a peptide capture molecule provided on at least a portion of wall surface and bottom surface in the reactor; and (c) synthesizing a protein or peptide from the nucleic acid using the cell-free synthesis system and immobilizing the protein or peptide in the reactor.

Abstract: A method for secondary-molding a polymer nano oriented crystal material in accordance with an embodiment of the present invention includes the steps of: heating the polymer nano oriented crystal material so that the polymer nano oriented crystal material changes into a mobile phase or a melt having a dense entanglement network structure; molding the polymer nano oriented crystal material which changed into the mobile phase or the melt including the dense entanglement network in the step; and cooling the polymer nano oriented crystal material, which has undergone the step, until the polymer nano oriented crystal material changes into an ordered phase.

Abstract: There is provided a method of manufacturing a protein array or peptide array suitable for an efficient screening of a functional protein or functional peptide. The method of manufacturing a protein array or peptide array includes the steps of: (a) preparing a nucleic acid immobilized on a solid support and a cell-free synthesis system in a reactor, in which a reactor array includes the reactor having a specific aperture shape and a protein capture molecule or a peptide capture molecule provided on at least a portion of wall surface and bottom surface in the reactor; and (c) synthesizing a protein or peptide from the nucleic acid using the cell-free synthesis system and immobilizing the protein or peptide in the reactor.