Abstract: A laser device includes: a laser unit that outputs laser light; an output end that launches the laser light; a first fusion splice portion; and a second fusion splice portion. In each of the first fusion splice portion and the second fusion splice portion, two multi-mode fibers are fusion-spliced. Each of the two multi-mode fibers include a core through which the laser light propagates and a cladding that surrounds the core. The first fusion splice portion is disposed closer to the laser unit than is the second fusion splice portion. At least a part of the core in the first fusion splice portion contains a dopant that is the same type as a dopant contained in the cladding in the first fusion splice portion for decreasing a refractive index.

Abstract: A multilayer ceramic capacitor includes a multilayer body including dielectric layers, inner-electrode layers, and outer electrodes coupled to the inner-electrode layers. The multilayer body includes Ba, Ti, Ca, Mg, Zr, and R, and when the Ti content is defined as 100 parts by mole, the relative amounts are as follows: Ca, 0.03 parts by mole or more and 0.15 parts by mole or less, Mg, 0.01 parts by mole or more and 0.09 parts by mole or less, R, 2.5 parts by mole or more and 8.4 parts by mole or less; Zr, 0.05 parts by mole or more and 3.00 parts by mole or less: Si, 0.5 parts by mole or more and 4.0 parts by mole or less; and P, 0.005 parts by mole or more and 0.500 parts by mole or less. Ca is in a vicinity of the center of crystal grains contained in the dielectric layers.

Abstract: A motor gear unit for a disc brake apparatus includes an electric motor, a speed reduction mechanism configured to transmit rotation of the electric motor to a plurality of rotary-to-linear motion conversion mechanisms arranged in a plurality of cylinders provided in a caliper, and a housing accommodating the electric motor and the speed reduction mechanism. The speed reduction mechanism includes a plurality of final gears connected directly or via another member to the plurality of rotary-to-linear motion conversion mechanisms and a power distribution mechanism that includes one support shaft and that is configured to distribute and transmit input power to the plurality of final gears. The power distribution mechanism is supported by the housing by supporting and fixing end portions of the support shaft on axially both sides to the housing.

Abstract: A measurement section (1) performs a mass spectrometric analysis for each micro area within a measurement area on a sample. A dimension reduction processor (23) performs data processing by non-linear dimension reduction using manifold learning on mass spectrometric data for each micro area, to obtain, for each micro area, a set of data reduced to three dimensions from the dimensions corresponding to the number of mass-to-charge-ratio values. A display color determiner (24) determines a color for each of the points corresponding to the data of the micro areas after the dimension reduction, by arranging those points within a three-dimensional space having three axes representing the three dimensions, with three primary colors respectively assigned to the three axes.

Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.

Abstract: A redundant resolver is configured of a stator and a rotor that form a pair, wherein the rotor is a rotor with a shaft angle multiplier of Nx having Nx (Nx is a natural number) salient poles, the stator is such that n teeth T1 to Tn, where n is a natural number, are disposed sequentially in a circumferential direction, configuring M systems by being divided into M in the circumferential direction, and having an angle of 360/M degrees when angles of the teeth configuring one system are totaled, a one-phase excitation winding and a two-phase output winding are wound around each of the teeth T1 to Tn, excitation signals of the same frequency are applied by differing excitation circuits to the respective excitation windings, an output order per system is Nout (Nout is a natural number), and an abnormality is detected based on output signals of the M systems.

Abstract: An analysis device collects data by performing a predetermined analysis on each specimen and processes the data.

Abstract: A fuel cell separator includes a separator main body having a first surface and a second surface, and a first seal member disposed on the first surface. When a region on the first surface of the separator main body corresponding to an electrode member disposed on the second surface is defined as a power generation region, and a region on the first surface of the separator main body corresponding to an in-cell seal member is defined as a seal region, a displacement/vibration reducing member made of polymer is disposed at a part of the seal region. The displacement/vibration reducing member includes multiple protrusions and a coupling portion. When viewed in plan view, an axis line connecting the centers of the figures of the adjacent protrusions does not coincide with a center line passing through the widthwise center of the coupling portion. The coupling portion has a gate cut mark.

Abstract: Imaging mass spectrometry section (100) performs a mass spectrometric analysis at each of the micro areas set within a measurement area on a target sample, and acquires a graphical image showing a signal-intensity distribution at a specific mass-to-charge ratio or mass-to-charge-ratio range. Quantitative analysis section (300) determines a quantitative value using an analysis result obtained by performing an analysis on the sample collected from each predetermined site within the measurement area of the target sample, using a predetermined analytical technique exhibiting a higher level of quantitative determination performance than the mass spectrometric analysis.

Abstract: A charged particle emission device includes a pre-emission state detector configured to detect a pre-emission charged state which is a charged state of a charged object before the charged particles are emitted, a learned model configured to receive a charged state of a charged object and a control parameter related to a control amount used for control of the charged particles to be emitted to the charged object to generate an estimated charged state which is a charged state of the charged object after the charged particles are controlled under the control parameter and emitted, an estimated charged state generator configured to input the pre-emission charged state and a plurality of control parameters to the learned model to generate a plurality of estimated charged states corresponding to the pre-emission charged state and the plurality of control parameters.

Abstract: A charged particle emission device includes a pre-emission state detector configured to detect a pre-emission charged state which is a charged state of the charged object before charged particles are emitted, an emission time generator configured to generate an emission time based on a past emission time of charged particles and a charged state of the charged object after the emission, emission processor circuitry configured to emit charged particles to the charged object which is in the pre-emission charged state based on the generated emission time, a post-emission state detector configured to detect a post-emission charged state which is a charged state of the charged object after the charged particles are emitted, machine learning processor circuitry configured to cause a machine learning model to learn a correspondence among the pre-emission charged state, the post-emission charged state, and the emission time generated by the emission time generator.

Abstract: A permanent-magnet synchronous motor and an electric power steering device are driven by a first system including a first armature winding and a first control apparatus and by a second system including a second armature winding and a second control apparatus and are configured in such a way that if one system fails, driving by the one system is stopped but the driving is continued by the other system.

Abstract: In an imaging mass spectrometer for analyzing the same kind of samples using results of imaging mass spectrometric analysis performed on those samples, a measurement section (1) acquires mass spectrometric data by performing an analysis on each of the micro areas on a sample. A region-of-interest setter (32) sets an ROI on each sample, and divides each ROI into the same number of subregions each including the micro areas so that the subregions correspond to each other on the samples respectively covering roughly identical sites on the samples. An individual-index-value calculator (33) calculates an individual index value for each subregion, using mass spectrometric data acquired at the micro areas in the subregion, the individual index value reflecting a similarity or difference among the samples in terms of a degree of expression of each m/z value.

Abstract: An imaging mass spectrometer includes an analysis executing section that executes MSn analysis (n?2) for a target component on each of a plurality of micro regions set in a two-dimensional or three-dimensional measurement region on a sample to collect data; a product ion extracting section that extracts product ions observed in the sample based on at least a part of the data collected by the analysis executing section; a two-dimensional distribution image creating section that creates a two-dimensional distribution image based on data of precursor ions and two-dimensional distribution images based on data of the product ions at the time of the MSn analysis; and a distribution relationship visualization section that examines a relationship of the two-dimensional distribution images of the precursor ions and the product ions, creates a figure or graph indicating an inclusion relationship of the two-dimensional distribution images, and displays the figure or graph.

Abstract: An imaging mass spectrometer according to one aspect of the present invention includes an analysis executing section (1) configured to collect data by executing predetermined analysis on each of a plurality of micro regions set in a two-dimensional measurement region (50) on a sample (50) or a three-dimensional measurement region in the sample; a first image creating section (21) that uses the data obtained by the analysis executing section (1) to create one or a plurality of first distribution images each reflecting a distribution of one or a plurality of specific components included in the sample (50); a formula storage section (23) that stores, as a formula, a chemical reaction formula including at least the one or a plurality of specific components as elements, or a calculation formula including an amount of the specific component as element; a signal value calculating section (25) that calculates different signal values from the signal values in the micro regions constituting the one or the plurality of

Abstract: An imaging mass spectrometer includes an analysis executing section that executes MSn analysis for a target component on each of a plurality of micro regions set within a two-dimensional measurement region on a sample to collect data; an ion selecting section that selects a plurality of kinds of product ions derived from, or assumed to be derived from, the target component based on at least a part of the data collected by the analysis executing section; and a distribution image creating section that determines, using signal strength of each of the kinds of product ions in each micro region within the measurement region. a small region in which all of the kinds of product ions are detected or a small region assumed to have high reliability that all of the kinds of product ions are derived from the target component, and creates a distribution image visualizing the small region.

Abstract: Provided is a rotating electric machine, including: a stator including: an annular core back; and a plurality of teeth projecting in a radial direction from the core back and being arranged in a circumferential direction, the plurality of teeth having slots each formed between the plurality of teeth adjacent to each other in the circumferential direction; and a rotor including: an annular rotor core which is arranged coaxially with the stator through a magnetic gap; and a plurality of magnetic poles arranged on the rotor core in the circumferential direction, wherein the rotor core includes a plurality of segment cores formed by dividing the rotor core in the circumferential direction with at division surfaces, and wherein the number of segments of the rotor core is different from a divisor and a multiple of the greatest common divisor of the number of poles of the rotor and the number of slots.

Abstract: A user enters structures of a plurality of metabolite candidates contained in a sample. A dissociation pattern predictor predicts a dissociation pattern for each metabolite candidate. An MS/MS spectrum estimator estimates an MS/MS spectrum and stores it in a teaching data storage. An imaging mass spectrometry unit acquires measured MS/MS spectra for each measurement point within a measurement range on a sample by performing an MS/MS analysis in which a precursor ion based on mass information of each metabolite candidate is used as an analysis target. A multivariate analysis processor performs a multivariate analysis in which the peak information based on the MS/MS spectra stored in the teaching data storage is used as teaching data, to classify measured MS/MS spectra at each measurement point into a plurality of metabolite candidates. Based on the classification result, a spatial distribution creator creates an image showing a spatial distribution for each metabolite candidate.

Abstract: A reference image data input section reads, from a Raman spectroscopic analyzer, a set of data constituting a Raman spectroscopic imaging graphic for a target sample. An ROI specification processor) displays a Raman spectroscopic imaging graphic based on those data on a display unit. An operator viewing the image operates an input unit to set a plurality of ROIs. Then, the ROI specification processor determines position information of the ROIs. An analysis processor extracts the data of measurement points corresponding to the set ROIs from MS imaging data acquired by an analysis performed by an imaging mass spectrometry unit for the same target sample. The processor also calculates an average mass spectrum from the data of a large number of measurement points for each ROI, and performs a multivariate analysis on the plurality of average mass spectrum data to compare the ROIs with each other or divide them into groups.

Abstract: An image creator (33) creates an optical image and a mass spectrometric (MS) image for each m/z for a measurement area on the same sample, and an image alignment processor (34) equalizes resolutions and aligns the images. A regression analysis executer (35) performs partial least squares regression (PLS) to create a regression model, using a matrix based on the MS imaging data as an explanatory variable and a matrix, which has a luminance value for each pixel as an element and has been created from the optical image, as an explained variable. An image creator (33) applies the explanatory variable, that is, a signal intensity value for each mass-to-charge ratio value in each pixel of the MS imaging data, to the regression model to create an estimation image. A display processor (39) displays a reference image and the estimation image on a screen of a display unit (5). Thus, an operator can confirm the degree of similarity in distribution between the MS image and the optical image.