Abstract: The present invention relates to an electrophotographic photosensitive member obtained by providing, on a conductive support, a conductive layer containing conductive particles having a volume-average particle diameter of 0.1 ?m or more, an intermediate layer, and a photosensitive layer in the stated order in which the conductive layer contains a polyolefin resin containing a specific repeating structural unit at a specific ratio, and a process cartridge and an electrophotographic apparatus each having the electrophotographic photosensitive member.

Abstract: Provided is a combination drug. The present invention provides a pharmaceutical agent comprising (1) a HER2 inhibitor having a pyrrolopyrimidine skeleton or pyrazolopyrimidine skeleton, and (2) not less than one pharmaceutical agent selected from an mTOR inhibitor, a PI3 kinase inhibitor and a cMet inhibitor in combination.

Abstract: An apparatus which has a load that consumes a predetermined amount of electric power per unit time includes a power source circuit configured to generate a voltage for driving the load, a capacitor which is connected to a supply line for supplying electric power to the load from the power source circuit and configured to stabilize a potential of the load, a first supply circuit which can supply electric power smaller than the predetermined amount to the capacitor and can discharge a charge from the capacitor, a second supply circuit which can supply electric power larger than the predetermined amount to the capacitor, a switch circuit configured to operate each of the first supply circuit and the second supply circuit, and a holding circuit configured to hold information based on the operation of the first supply circuit.

Abstract: The present invention provides a method for treating cancer, which includes selecting a patient coexpressing HER2 and HER3, and administering an effective amount of a HER2 inhibitor to the patient.

Abstract: A recording apparatus provided with an interface for supplying an electric power to a connected electronic apparatus, and capable of performing a recording operation on a recording medium by the use of a recording head. A power source supplying unit supplies predetermined electric power to the electronic apparatus connected to the interface, and a detecting unit detects that the electronic apparatus has been connected. An acquiring unit acquires power information of the electronic apparatus, such as information indicating the nature of the interface or information indicating the power requirements. Based on detection of the connection by the detecting unit and the power information acquired by the acquiring unit, a control unit effects a change over of control of the recording operation.

Abstract: In an electrophotographic photosensitive member having a support, a conductive layer formed on the support, an intermediate layer formed on the conductive layer, and a photosensitive layer formed on the intermediate layer, the conductive layer has been formed by using a conductive layer coating fluid which contains TiO2 particles coated with oxygen deficient SnO2 having an average particle diameter of from 0.20 ?m or more to 0.60 ?m or less, and has a volume resistivity of from more than 8.0×108 ?cm to 1.0×1011 ?cm or less. The electrophotographic photosensitive member can keep charging lines from occurring.

Abstract: A manufacturing method of a magnetoresistance element having a pinned magnetic layer, a non-magnetic intermediate layer, and a free magnetic layer, the method includes forming at least one thin film of the non-magnetic intermediate layer and the free magnetic layer at a pressure of 8.0×10?3 Pa or less in the vicinity of a substrate using a sputtering apparatus. The apparatus includes a vacuum chamber in which a cathode and a substrate holder are arranged, a first exhausting apparatus connected to an exhausting port of the vacuum chamber, a gas introduction mechanism to introduce a gas toward the target, a first pressure regulator to cause a pressure difference between a target space and a center space outside the target space, a second pressure regulator to cause a pressure difference between the center space and a substrate space, and a second exhausting apparatus to exhaust the center space.

Abstract: The present invention provides a pharmaceutical agent containing an HER2 inhibitor and a hormonal therapeutic agent or anti-cancer agent in combination. The present invention provides a pharmaceutical agent containing (1) an HER2 inhibitor having a pyrrolopyrimidine skeleton or pyrazolopyrimidine skeleton, and (2) a hormonal therapeutic agent or an anti-cancer agent in combination.

Abstract: A manufacturing method of a magnetoresistance element having a pinned magnetic layer, a non-magnetic intermediate layer, and a free magnetic layer, the method includes forming at least one thin film of the non-magnetic intermediate layer and the free magnetic layer at a pressure of 8.0×10?3 Pa or less in the vicinity of a substrate using a sputtering apparatus. The apparatus includes a vacuum chamber in which a cathode and a substrate holder are arranged, a first exhausting apparatus connected to an exhausting port of the vacuum chamber, a gas introduction mechanism to introduce a gas toward the target, a first pressure regulator to cause a pressure difference between a target space and a center space outside the target space, a second pressure regulator to cause a pressure difference between the center space and a substrate space, and a second exhausting apparatus to exhaust the center space.

Abstract: In an electrophotographic photosensitive member having a support, a conductive layer formed on the support, an intermediate layer formed on the conductive layer, and a photosensitive layer formed on the intermediate layer, the conductive layer has been formed by using a conductive layer coating fluid which contains TiO2 particles coated with oxygen deficient SnO2 having an average particle diameter of from 0.20 ?m or more to 0.60 ?m or less, and has a volume resistivity of from more than 8.0×108 ?cm to 1.0×1011 ?cm or less. The electrophotographic photosensitive member can keep charging lines from occurring.

Abstract: The present invention provides a method for treating cancer, which includes selecting a patient coexpressing HER2 and HER3, and administering an effective amount of a HER2 inhibitor to the patient.

Abstract: An object of the present invention is to provide a method of fabricating a substrate, and the like which excels in flatness, ten-point average roughness and surface roughness of substrates and flattens and smoothes the substrate surface. The method of fabricating a substrate includes a step of correcting flatness, a step of correcting surface unevenness in which the substrate surface is polished by means of a polishing pad with a hardness defined by JIS K 6253 of 70 or more, and a step of finishing surface roughness, to therefore achieve the above objectives. Such a substrate can be used for masks and mirrors of semiconductor exposure, discs for flying height tests of the hard-disk magnetic heads, and pharmaceutical test preparation, and the like.

Abstract: There is provided a recording apparatus for receiving recording data from an electronic apparatus or a host computer activated by being supplied with a power source through an interface, and performing a recording operation on a recording medium by the use of a recording head. This recording apparatus comprises power source supplying means for supplying predetermined electric power to the electronic apparatus, detecting means for detecting that the electronic apparatus has been connected, and control mans for changing over the control of the recording operation when the detecting means has detected the connection or non-connection of the electronic apparatus. Also, there is provided an electronic apparatus for effecting communication with a first external device activated by being supplied with a power source through a first interface and a second external device connected thereto through a second interface, and performing an operation.

Abstract: There is provided a recording apparatus for receiving recording data from an electronic apparatus or a host computer activated by being supplied with a power source through an interface, and performing a recording operation on a recording medium by the use of a recording head. This recording apparatus comprises power source supplying means for supplying predetermined electric power to the electronic apparatus, detecting means for detecting that the electronic apparatus has been connected, and control mans for changing over the control of the recording operation when the detecting means has detected the connection or non-connection of the electronic apparatus. Also, there is provided an electronic apparatus for effecting communication with a first external device activated by being supplied with a power source through a first interface and a second external device connected thereto through a second interface, and performing an operation.

Abstract: A manufacturing method of a magnetoresistance element having a pinned magnetic layer, a non-magnetic intermediate layer, and a free magnetic layer, the method includes forming at least one thin film of the non-magnetic intermediate layer and the free magnetic layer at a pressure of 8.0×10?3 Pa or less in the vicinity of a substrate using a sputtering apparatus. The apparatus includes a vacuum chamber in which a cathode and a substrate holder are arranged, a first exhausting apparatus connected to an exhausting port of the vacuum chamber, a gas introduction mechanism to introduce a gas toward the target, a first pressure regulator to cause a pressure difference between a target space and a center space outside the target space, a second pressure regulator to cause a pressure difference between the center space and a substrate space, and a second exhausting apparatus to exhaust the center space.

Abstract: An inkjet printing apparatus is adapted to use a non-contact method for detecting the presence and the amount of liquid, in the form of ink droplets discharged from a printhead or ink tank, using electromagnetic waves in the form of infrared rays. The apparatus and method employ an infrared sensor to detect infrared radiation emitted by the ink in proportion to the amount of ink present. The apparatus and method further employ one of various shielding members to prevent the intrusion of infrared radiation noise into the infrared sensor field of detection, and, in some aspects, a fan to control air flow within the field of detection. The result is less noise in the detection signals of the infrared sensor, and therefore a more sensitive and more reliable liquid detection method and liquid detection apparatus.

Abstract: Each of pixels of recorded image is formed by a plurality of dots composed with ink droplets ejected from a plurality of different orifices at individual different main-scannings. With this recording process, the variation of ink ejection characteristics between a plurality of orifices in a recording head can be reduced in forming pixels.

Abstract: There is provided a recording apparatus for receiving recording data from an electronic apparatus or a host computer activated by being supplied with a power source through an interface, and performing a recording operation on a recording medium by the use of a recording head. This recording apparatus comprises power source supplying means for supplying predetermined electric power to the electronic apparatus, detecting means for detecting that the electronic apparatus has been connected, and control mans for changing over the control of the recording operation when the detecting means has detected the connection or non-connection of the electronic apparatus.

Abstract: In the present invention, the minimum necessary consumption of ink can recover the channel miss state of the plurality of nozzles. The present invention provides a recovery processing method of an ink jet printing apparatus for forming images using a print head having a plurality of nozzles for ejecting ink droplets. The method comprises a first step for detecting channel miss state of said plurality of nozzles, and a second step for executing at least one of different recovery processes depending on the channel miss states of said plurality of nozzles detected in the first step.

Abstract: An inkjet printing apparatus, is adapted to use a non-contact method for detecting the presence and the amount of liquid, in the form of ink droplets discharged from a printhead or ink tank, using electromagnetic waves in the form of infrared rays. The apparatus and method employ an infrared sensor to detect infrared radiation emitted by the ink in proportion to the amount of ink present. The apparatus and method further employ one of various shielding members to prevent the intrusion of infrared radiation noise into the infrared sensor field of detection, and, in some aspects, a fan to control air flow within the field of detection. The result is less noise in the detection signals of the infrared sensor, and therefore more sensitive and more reliable liquid detection method and liquid detection apparatus.