Abstract: An observation system includes an observation apparatus including a housing having an arrangement surface for placement of a sample, the sample including a culture medium, and an external illumination unit which is disposed outside the housing and includes at least one light source configured to emit illumination light. At least a part of the arrangement surface is formed of a transparent member having an optically transparent property. The observation apparatus includes an imaging unit which is provided in the housing and includes an image sensor configured to image, via the transparent member, the sample illuminated by the illumination light from the external illumination unit to acquire images of at least three colors.

Abstract: A cell observation system according to the present invention includes: a first image-acquisition device disposed in an incubator and acquires a first image of cells in a culturing vessel; a second image-acquisition device disposed outside the incubator; a processing device connected to the first and second image-acquisition devices; and a display. The second image-acquisition device includes a second image-acquisition unit that acquires a second image of the interior of the culturing vessel that removed from the incubator, a support that supports the second image-acquisition unit and the culturing vessel, and a position measuring unit that measures a position between the culturing vessel and the second image-acquisition unit at the time of acquiring the second image. The processing device extracts target cells in the first image, calculates positions of the target cells, and displays the relationship between the positions of the target cells and the second image.

Abstract: A cell observation system according to the present invention includes: a first image-acquisition device disposed in an incubator and acquires a first image of cells in a culturing vessel; a second image-acquisition device disposed outside the incubator; a processing device connected to the first image-acquisition device and the second image-acquisition device; and a display displays at least a region of the first image, as well as the second image. The second image-acquisition device includes a second image-acquisition unit that acquires a second image of the interior of the culturing vessel, that removed from the incubator. The processing device extracts target cells in the first image, calculates positions at which the extracted target cells are present and stores the positions in the memory, and causes the display to display the positions at which the target cells are present in a superimposed manner on an indication indicating the culturing vessel.

Abstract: A quantitative evaluation apparatus of the present invention includes: a counter that counts the numbers of cells or densities of cells contained in individual images of a plurality of image-capturing regions in a culturing vessel for culturing the cells; an evaluation-value calculating portion that calculates an evaluation value related to variation in the distribution of the cells in the culturing vessel on the basis of the numbers of the cells or the densities of cells counted by means of the counter in each of the images; a determining portion that determines whether or not the evaluation value calculated by the evaluation-value calculating portion is in a range of a prescribed threshold; and a display that displays determination result determined by the determining portion.

Abstract: A medium changing device includes a lid disposed at a position where two or more regions in which a medium may be stored are covered therewith, the regions being disposed adjacent to each other and being open upward; one or more flow-path members each disposed so as to penetrate the lid, and each disposed at a position where one of the regions is bridged to another therewith when the lid is disposed at the position where the regions are covered; and a pump disposed on the other side of the lid and acting on the intermediate sections of the flow-path members, exposed on the other side, so as to cause the medium to flow from the opening at one end toward the opening at the other end of each of the flow-path members.

Abstract: Provided is an observation apparatus including: a housing that has, in a top face thereof, a transmission window on which a container accommodating cells can be placed and through which light can pass; a camera portion that is accommodated in the housing and that captures observation light coming from the cells irradiated with illumination light emitted from an illumination portion and entering the housing by passing through a bottom face of the container and the transmission window of the housing; and a housing-interior heating portion that is accommodated in the housing and that heats the cells.

Abstract: A cell observation system includes an imaging element that acquires images of the inside of a culture container in which cells are cultured, the imaging element acquiring the images over time; a computer configured to: quantitatively analyze a culture state of the cells cultured in the culture container on the basis of each of the images acquired by the imaging element; and statistically analyze the quantitatively analyzed data; and a display that displays statistical analysis results in the culture container within a plurality of subculture periods obtained by the computer in a manner allowing comparison of the statistical analysis results.

Abstract: An observation device includes: a housing having, in a top surface, a glass window on which a vessel accommodating samples is placed and through which illumination light is transmitted; and an image acquisition unit accommodated in the housing and configured to capture transmitted light obtained after illumination light is transmitted through the samples from above, is transmitted through the glass window, and enters the housing.

Abstract: An observation apparatus including: a top plate on which a container in which a specimen is accommodated can be placed, and through which illumination light can pass; a light source that emits the illumination light upward from below the specimen; an objective lens that focuses, below the specimen and the top plate, transmitted light which is the illumination light that has passed through the specimen from thereabove and that has passed through the top plate; and a camera that captures the transmitted light, wherein the light source emits the illumination light toward an area above the specimen from outside the objective lens in a radial direction, and the top plate is provided with a mark that specifies a viewing-field area of the camera.

Abstract: An observation apparatus including: a light-source that emits illumination light and excitation light upward from below a specimen; and an image-capturing optical system having an objective lens that focuses, below the specimen, transmitted light, which is the illumination light that is emitted from the light-source, that is reflected above the specimen, and that has passed through the specimen, and fluorescence that is generated in the specimen that has been irradiated with the excitation light emitted from the light-source, wherein the light-source is disposed radially outside the objective lens.

Abstract: An observation assistance device of the present invention includes: an information storage unit that stores sample state information showing a sample state change, a type of sample, a type of fluorescent substance, and an observation condition in fluorescence observation performed on a predetermined sample, and under a predetermined observation condition; an input unit via which inputs the type of sample to be observed and the type of fluorescent substance to be used; an assistance-display generating unit that reads sample state information and an observation condition of fluorescence observation performed on the same type of sample as the type of sample input, using the same type of fluorescent substance as the type of fluorescent substance, and generates an assistance display showing the sample state information in relation to the two or more parameters included in the observation condition; and a display unit that displays the generated assistance display.

Abstract: In an exemplary embodiment, a coil component includes: a drum core 10 having a winding shaft 12 and a pair of flange parts 14a, 14b; and a coil 30 constituted by a conductive wire 34 with insulating sheath 38 being wound around the winding shaft 12, forming one or more layers 32 in a direction which crosses an axial direction of the winding shaft 12; wherein the conductive wire 34 is exposed to and faces, at each of the one or more layers 32, a void 64 formed between the flange part 14a and the flange part 14b, wherein the void 64 is present at each of the one or more layers 32 in succession from one end to the other end of the conductive wire 34 as viewed in the axial direction of the winding shaft 12.

Abstract: Provided is an observation apparatus and an observation method with which it is possible to observe imaging subjects, such as cells or the like, without labeling the imaging subjects and without causing an increase in the apparatus size. Provided is an observation apparatus including: a light-source unit that emits illumination light upward from below a sample; and an image-capturing optical system that has an objective lens that collects transmitted light, which is the illumination light emitted from the light-source unit that has passed through the sample by being reflected above the sample and that captures, below the sample, the transmitted light collected by the objective lens.

Abstract: An observation assistance device of the present invention includes: an information storage unit that stores sample state information showing a sample state change, a type of sample, a type of fluorescent substance, and an observation condition in fluorescence observation performed on a predetermined sample, and under a predetermined observation condition; an input unit via which inputs the type of sample to be observed and the type of fluorescent substance to be used; an assistance-display generating unit that reads sample state information and an observation condition of fluorescence observation performed on the same type of sample as the type of sample input, using the same type of fluorescent substance as the type of fluorescent substance, and generates an assistance display showing the sample state information in relation to the two or more parameters included in the observation condition; and a display unit that displays the generated assistance display.

Abstract: Provided is a microscope provided with: a scanner that scans an excitation beam coming from a light source; an objective optical system that focuses the scanned excitation beam onto a sample and that collects fluorescence generated at individual scanning positions in the sample; a detector that detects the collected fluorescence; a light blocking member that is disposed between the detector and the system and that partially blocks the collected fluorescence; a switching portion that switches the positional relationship between the member and a light-focusing point of the excitation beam in the sample between an optically conjugate positional relationship, in which an in-focus fluorescence generated at the light-focusing point passes through the member, and a non-conjugate positional relationship, in which the in-focus fluorescence is blocked by the member; and a computing portion that computes a difference between fluorescence signals acquired by the detector in the two positional relationships.

Abstract: An observation device including: a stage having a transparent pedestal surface; an illumination system under the pedestal surface, the illumination system emitting illumination light toward the pedestal surface; and an object system under the pedestal surface for capturing transmission light generated from the illumination light, reflected off a reflection surface and transmitted through a sample. Wherein a first light path in the illumination system is different from a second light path in the object system, in a first pupil surface of the illumination system, the illumination system generates the illumination light by restricting light in a first transparent region, in a second pupil surface of the object system, the object system restricts the transmission light in a second transparent region, and the second transparent region has first and second subregions with different transmittance, the second subregion located between the first subregion and an edge of the second transparent region.

Abstract: In an embodiment, a coil component includes: a core 10; a coil conductor 40 having a spiral part 42 placed inside the core 10, and a lead part 48 which is led out from the spiral part 42 to the principal outer surface, constituting the bottom face 28, of the core 10, and which includes an end part 46 that serves as an external terminal 49; an insulated terminal 60 electrically insulated from the coil conductor 40, which is fitted onto and bonded to the core 10, and which has a bottom part 64 positioned on the bottom face 28, a top part 62 positioned on the top face 26, and a side part 66 coupling the bottom part 64 and the top part 62, where the top part 62 and side part 66 have an opening 68 in which an adhesive 82 is filled.

Abstract: An observation device includes an illuminating optical system that emits illuminating light obliquely upward from below a sample; and an objective optical system that images transmitted light, which is the illuminating light emitted from the illuminating optical system, reflected above the sample, and passed through the sample, the objective optical system imaging the transmitted light below the sample and via a different path from that of the illuminating optical system. The illuminating optical system includes a light source, a mask that restricts light, which is emitted from the light source, to a particular emission region, and a collimating optical system that converts the light restricted by the mask into substantially parallel light, and the illuminating optical system is arranged so that when the region is projected onto a pupil plane of the objective optical system, a projected image of the region partially overlaps a peripheral portion of the pupil.

Abstract: Provided is an observation apparatus including: a housing that has, in a top face thereof, a transmission window on which a container accommodating cells can be placed and through which light can pass; a camera portion that is accommodated in the housing and that captures observation light coming from the cells irradiated with illumination light emitted from an illumination portion and entering the housing by passing through a bottom face of the container and the transmission window of the housing; and a housing-interior heating portion that is accommodated in the housing and that heats the cells.

Abstract: A method of manufacturing an intermediate product for an interposer including a glass substrate having a plurality of through holes is provided. The method includes a step of forming a resin layer on a support substrate, and a step of forming a laminated body by adhering the glass substrate having the plurality of through holes on the resin layer. The glass substrate having the plurality of through holes has a thickness within a range of 0.05 mm to 0.3 mm.