Abstract: The present invention relates to an ultrasound elastography system (10) for providing an elastography measurement result of an anatomical site (32) a corresponding method. The system (10) is configured to visualize a suitability for shear wave elastography of the region of interest (33) to the user within the ultrasound image (52) and/or to recommend an elastography acquisition plane (48, 50) for conducting shear wave elastography to the user. By this, proper selection of a location for an elastography measurement may be supported.

Abstract: Extracorporeal motion (130) relative to a medical subject being imaged is detected, through the imaging or from motion detectors on the imaging probe, and either backed out of the medical images so that it can be determined whether lung sliding exists or measured to determine whether lung sliding detection is to be suspended due to excessive extracorporeal motion. Image sub-regions (164, 168) corresponding to respective ones of the images are selected for image-to-image comparison such that the selected sub-regions contain only body tissue that is, with respect to imaging depth in the acquiring of the images, shallower than an anatomical landmark within the images. Based on a result of the comparing, lung sliding detection that entails examining image data deeper than the landmark may be initialized.

Abstract: The present invention proposes an ultrasound imaging system and method for measuring a property of a region of interest in a subject by using shear wave, wherein an ultrasound probe is configured to sequentially transmit, to each of a plurality of focal spots (320, 322, 324) in the region of interest, a push pulse (310, 312, 314) for generating a shear wave (330, 332, 334), each of the plurality of focal spots having a mutually different depth value (z1, z2, z3), and to receive ultrasound echo signals adjacent (350, 352, 354) to each of the plurality of focal spots; a shear wave detector is configured to derive, for each of the plurality of focal spots, a first parameter indicating a property of the generated shear wave, based on the received ultrasound echo signals; and a property estimator is configured to estimate a second parameter indicating the property of the region of interest 342 as a function of the derived first parameters.

Abstract: Existing gas pocket detection approaches are based on visual observations of B-mode ultrasound images showing comparisons between normal soft tissue and gas pockets, which are time-consuming and dependent on operator experience. The present invention proposes an ultrasound system and a method of detecting a gas pocket. The ultrasound system comprises: an ultrasound probe (110) for transmitting an ultrasound signal toward the ROI and acquiring an ultrasound echo signal reflected from the ROI along a plurality of scanning lines; an obtaining unit (130) for obtaining a second harmonic component of the ultrasound echo signal for each depth of a plurality of depths along each scanning line of the plurality of scanning lines; and a deriving unit (140) for deriving a change in a center frequency of the second harmonic component along with the depth.

Abstract: The embodiments disclose an ultrasound system comprising: a probe configured to obtain ultrasound data relating to scanning region including at least part of a pleural interface of a lung; and a data analyzer, configured to automatically detect information for determining lung sliding and/or lung point using one or more cross correlation maps derived from the data. The embodiments also disclose a method thereof.

Abstract: Ultrasound-based acoustic streaming for deciding whether material is fluid is dependent upon any one or more of a variety of criteria. Examples are displacement, speed (230), temporal or spatial flow variance, progressive decorrelation, slope or straightness of accumulated signal to background comparisons over time, and relative displacement to adjacent soft tissue. Echogenicity-based area identification is combinable with the above movement characteristic detection in the deciding. Fluid pool identification is performable from the area-limited acoustic streaming testing and ultrasound attenuation readings. Candidates from among the areas (210) are screenable based on specific shapes or bodily organs detected. Natural flow can be excluded from streaming detection by identification of blood vessels (206). Processing for each FAST ultrasound view (202), or for the entire procedure, is performable automatically, without need for user intervention or with user intervention to identify suspected areas.

Abstract: In a diagnostic scanner for shear wave elastography imaging an ultrasound exposure safety processoris is configured for spatially relating respective definitions of an imaging zone (324), and an extended dead-tissue zone (312) that includes both a dead-tissue zone and a surrounding margin. Based on whether a push pulse focus (344, 348, 352) is to be within the extended dead-tissue zone, the processor automatically decides as to a level of acoustic power with which the pulse is to be produced. If it is to be within, the pulse may be produced with a mechanical index, a thermal index, and/or a spatial-peak-temporal-average intensity that exceeds respectively 1.9, 6.0 and 720 milliwatts per square centimeter. The imaging zone may be definable interactively so as to dynamically trigger the deciding and the producing, with optimal push pulse settings being dynamically derived automatically, without the need for user intervention.

Abstract: Ultrasound motion-estimation includes issuing multiple ultrasound pulses, spaced apart from each other in a propagation direction of a shear wave, to track axial motion caused by the wave. The wave has been induced by an axially-directed push. Based on the motion, autocorrelation is used to estimate an axial displacement. The estimate is used as a starting point (234) in a time-domain based motion tracking algorithm for modifying the estimate so as to yield a modified displacement. The modification can constitute an improvement upon the estimate. The issuing may correspondingly occur from a number of acoustic windows, multiple ultrasound imaging probes imaging respectively via the windows. The autocorrelation, and algorithm, operate specifically on the imaging acquired via the pulses used in tracking the motion caused by the wave that was induced by the push, the push being a single push.

Abstract: A device images time-wise in parallel using transducer elements of a group. The elements are of a current group and imaging is time-wise sequential by group. The groups may be spatially disposed with respect to each other so as to mutually intermesh element-wise. The imaging may include volumetric imaging. The device may be configured for not collectively using any of the elements to focus, nor to steer, a beam used in the imaging. The device may further be operable to transition between spacing states at least one of which is characterized by a respective minimum, nonzero, degree of intra-group, element-to-element non-adjacency, or may be fixed at a selected spacing state. The transitioning may be automatic, in response to input indicative of blood vessel size and/or depth.

Abstract: A structured porous metamaterial includes a three-dimensional matrix of at least one repeating base unit. The matrix is formed from an array of at least eight base units, each base unit including a platonic solid including at least one shaped void, wherein each base unit has void geometry tailored to provide a porosity of between 0.3 and 0.97, and to provide the metamaterial with a response that includes a Poisson's ratio of 0 to ?0.5 when under tension and compression, or negative linear compression (NLC), negative area compression (NAC), zero linear compression (ZLC), or zero area compression (ZAC) behaviour when under pressure.

Abstract: Existing gas pocket detection approaches are based on visual observations of B-mode ultrasound images showing comparisons between normal soft tissue and gas pockets, which are time-consuming and dependent on operator experience. The present invention proposes an ultrasound system and a method of detecting a gas pocket. The ultrasound system comprises: an ultrasound probe (110) for transmitting an ultrasound signal toward the ROI and acquiring an ultrasound echo signal reflected from the ROI along a plurality of scanning lines; an obtaining unit (130) for obtaining a second harmonic component of the ultrasound echo signal for each depth of a plurality of depths along each scanning line of the plurality of scanning lines; and a deriving unit (140) for deriving a change in a center frequency of the second harmonic component along with the depth.

Abstract: A temperature monitoring apparatus (40) is disclosed for monitoring a temperature within a tissue (10), in particular during a thermal ablation process. The monitoring apparatus comprises a temperature application unit (42) configured to introduce heating power into the tissue for heating the tissue. The monitoring apparatus further comprises an ultrasound unit (44) for emitting and receiving ultrasound waves and for determining a temperature in the measurement region (22, 24) of the tissue on the basis of ultrasound shear wave detection. The monitoring apparatus further comprises a temperature estimation unit (46) including a heat transfer model (48) for estimating a temperature in a region of interest (26) within the tissue, wherein the heat transfer model is based on medical images of the tissue.

Abstract: A non-imaging diagnostic ultrasound system for carotid artery diagnosis has a two dimensional array probe with a low element count and relatively large element size which can cover an area of the carotid artery at its bifurcation. The elements are operated independently with no phasing, and detect Doppler flow spatially beneath each element. The system produces maps of carotid blood flow in two or three dimensions and can assemble an extended view of the flow by matching segments of the carotid flow as the probe is moved over the vessel. Once the carotid artery has been localized, the degree of stenosis is assessed by automated measurements of peak systolic velocity and blood flow turbulence.

Abstract: A non-imaging diagnostic ultrasound system for carotid artery diagnosis has a two dimensional array probe (10) with a low element count and relatively large element size which can cover an area of the carotid artery at its bifurcation. The elements are operated independently with no phasing, and detect Doppler flow spatially beneath each element. The system produces maps of carotid blood flow in two or three dimensions and can assemble an extended view of the flow by matching segments of the carotid flow as the probe is moved over the vessel. Once the carotid artery has been localized, the degree of stenosis is assessed by automated measurements of peak systolic velocity and blood flow turbulence.

Abstract: A method for aligning spatially different subvolumes of ultrasonic data of a blood vessel comprising: acquiring temporally discrete signals of a blood vessel with elements of a two dimensional array of ultrasonic transducer elements from spatially different depths of scanning opposed by each transducer element, said array being located in a first position with respect to the blood vessel during the acquiring; Doppler processing the temporally discrete signals received from each transducer element to produce spectral Doppler data of the scanning depth opposed by each transducer element; producing a first three dimensional map of the spectral Doppler data in spatial relationship to the position of the array with respect to the blood vessel; acquiring temporally discrete signals of the blood vessel with elements of the two dimensional array of ultrasonic transducer elements from spatially different depths of scanning opposed by each transducer element, said array being located in a second position with respect t

Abstract: The present invention relates to an ultrasound elastography system (10) for providing a shear wave elastography measurement result of an anatomical site (32), wherein the ultrasound signal and image processing assembly (16) is further configured to determine a location (94, 95, 96) of a shear wave elastography measurement result within the three-dimensional image (98) of the anatomical site (32) and to display the location (94, 95, 96) of a shear wave elastography measurement result to the user. Further, a corresponding method is provided.

Abstract: The present invention relates to an ultrasound elastography system (10) for providing an elastography measurement result of an anatomical site (32) a corresponding method. The system (10) is configured to visualize a suitability for shear wave elastography of the region of interest (33) to the user within the ultrasound image (52) and/or to recommend an elastography acquisition plane (48, 50) for conducting shear wave elastography to the user. By this, proper selection of a location for an elastography measurement may be supported.

Abstract: A method for preparation of iloperidone is provided which comprises reacting 6-fluoro-3-(4-piperidinyl)-1,2-benzoisoxazole hydrochloride with 1-[4-(3-chloropropoxyl)-3-methoxyphenyl]ethyl ketone in an inorganic alkaline aqueous solution. A crystallization method of iloperidone is also provided which comprises adding seed crystal to the iloperidone solution in ethyl acetate, and then iloperidone crystal is obtained with high purity by controlling the temperature and the stirring speed.

Abstract: A device images time-wise in parallel using transducer elements of a group (428, 432, 436, 440). In some embodiments, the elements are of a current group and imaging is time-wise sequential by group. The groups may be spatially disposed (408, 412) with respect to each other so as to mutually intermesh element-wise. The imaging may include volumetric imaging. The device can be configured for not collectively using any of the elements to focus, nor to steer, a beam used in the imaging. The device might be operable to transition between spacing states (404, 408, 412) at least one of which is characterized by a respective minimum, nonzero, degree of intra-group, element-to-element non-adjacency (470), or may be fixed at one spacing state. The transitioning may be automatic, in response to input indicative of blood vessel size and/or depth.

Abstract: A method for preparation of iloperidone is provided which comprises reacting 6-fluoro-3-(4-piperidinyl)-1,2-benzoisoxazole hydrochloride with 1-[4-(3-chloropropoxyl)-3-methoxyphenyl]ethyl ketone in an inorganic alkaline aqueous solution. A crystallization method of iloperidone is also provided which comprises adding seed crystal to the iloperidone solution in ethyl acetate, and then iloperidone crystal is obtained with high purity by controlling the temperature and the stirring speed.