Patents by Inventor Shlomit Wizel

Shlomit Wizel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphic form XVI of fexofenadine hydrochloride
    Publication number: 20060217557
    Abstract: Provided is a crystalline (polymorphic) form of fexofenadine hydrochloride, denominated fexofenadine hydrochloride Form XVI.
    Type: Application
    Filed: October 3, 2005
    Publication date: September 28, 2006
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel, Boaz Gome, Igor Lifshitz
  • Polymorphs of clopidogrel hydrogensulfate
    Patent number: 7074928
    Abstract: Provided are new crystalline Forms III, IV, V and VI of clopidogrel hydrogensulfate and the amorphous form of clopidogrel hydrogensulfate, as well as their pharmaceutical compositions, and method of treatments with such compositions. Also provided are novel processes for preparation of clopidogrel hydrogensulfate Form I, Form II, Form III, Form IV, Form V, Form VI and amorphous form.
    Type: Grant
    Filed: January 8, 2003
    Date of Patent: July 11, 2006
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Revital Lifshitz-Liron, Eti Kovalevski-Ishai, Shlomit Wizel, Sharon Avhar-Maydan, Rami Lidor-Hadas
  • Fexofenadine crystal form and processes for its preparation thereof
    Publication number: 20060148851
    Abstract: Provided is a crystalline form of fexofenadine free base and processes for its preparation.
    Type: Application
    Filed: September 28, 2005
    Publication date: July 6, 2006
    Inventors: Shlomit Wizel, Ilan Kor-Sade
  • Tadalafil crystal forms and processes for preparing them
    Publication number: 20060111571
    Abstract: The present invention provides tadalafil crystal forms II, III, IV, VI, VII, and VIII, and processes for preparing these forms. The present invention also provides processes for preparing tadalafil forms I and V.
    Type: Application
    Filed: November 2, 2005
    Publication date: May 25, 2006
    Inventors: Shlomit Wizel, Barnaba Krochmal, Ariel Givant, Dov Diller
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20060106232
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: October 24, 2005
    Publication date: May 18, 2006
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam-Hildesheim, Revital Lifshitz-Liron, Shlomit Wizel
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20060106231
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: October 24, 2005
    Publication date: May 18, 2006
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam-Hildesheim, Revital Lifshitz-Liron, Shlomit Wizel
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20060100445
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: October 24, 2005
    Publication date: May 11, 2006
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam-Hildesheim, Revital Lifshitz-Liron, Shlomit Wizel
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20060100446
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: October 24, 2005
    Publication date: May 11, 2006
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam-Hildesheim, Revital Lifshitz-Liron, Shlomit Wizel
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20060100267
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: October 24, 2005
    Publication date: May 11, 2006
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam-Hildesheim, Revital Lifshitz-Liron, Shlomit Wizel
  • Novel sulfonation method for zonisamide intermediate in zonisamide synthesis and their novel crystal forms
    Publication number: 20060069267
    Abstract: The present invention relates to a novel sulfonation of an intermediate of zonisamide. The sulfonation processes using chlorosulfonic acid as well as acetic anhydride and sulfuric acid in an organic solvent are disclosed. Crystalline forms of benzisoxazole methane sulfonic acid (BOS-H) and its salts (BOS-Na, BOS-Ca, and BOS-Ba) and their novel preparation processes are disclosed.
    Type: Application
    Filed: November 14, 2005
    Publication date: March 30, 2006
    Inventors: Tamar Nidam, Marioara Mendelovici, Eduard Schwartz, Shlomit Wizel
  • Novel sulfonation method for zonisamide intermediate in zonisamide synthesis and their novel crystal forms
    Publication number: 20060063936
    Abstract: The present invention relates to a novel sulfonation of an intermediate of zonisamide. The sulfonation processes using chlorosulfonic acid as well as acetic anhydride and sulfuric acid in an organic solvent are disclosed. Crystalline forms of benzisoxazole methane sulfonic acid (BOS-H) and its salts (BOS-Na, BOS-Ca, and BOS-Ba) and their novel preparation processes are disclosed.
    Type: Application
    Filed: November 14, 2005
    Publication date: March 23, 2006
    Inventors: Tamar Nidam, Marioara Mendelovici, Eduard Schwartz, Shlomit Wizel
  • Sulfonation method for zonisamide intermediate in zonisamide synthesis and their novel crystal forms
    Patent number: 7015330
    Abstract: The present invention relates to a novel sulfonation of an intermediate of zonisamide. The sulfonation processes using chlorosulfonic acid as well as acetic anhydride and sulfuric acid in an organic solvent are disclosed. Crystalline forms of benzisoxazole methane sulfonic acid (BOS—H) and its salts (BOS—Na, BOS—Ca, and BOS—Ba) and their novel preparation processes are disclosed.
    Type: Grant
    Filed: November 5, 2002
    Date of Patent: March 21, 2006
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Tamar Nidam, Marioara Mendelovici, Eduard Schwartz, Shlomit Wizel
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20060058533
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: October 24, 2005
    Publication date: March 16, 2006
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam, Revital Lifshitz, Shlomit Wizel
  • Polymorphic forms of nateglinide
    Publication number: 20060004102
    Abstract: Provided are crystalline forms of nateglinide and processes for their preparation.
    Type: Application
    Filed: May 9, 2005
    Publication date: January 5, 2006
    Inventors: Shlomit Wizel, Gustavo Frenkel, Boaz Gome
  • Novel crystalline forms of gatifloxacin
    Publication number: 20050288302
    Abstract: Provided are novel crystalline forms of gatifloxacin denominated forms A, B, C, D, E1, F, G, H, I, and J, and methods for their preparation. Also provided are methods for making known crystalline forms of gatifloxacin, in particular forms omega and T2RP.
    Type: Application
    Filed: August 19, 2005
    Publication date: December 29, 2005
    Inventors: Valerie Niddam-Hildesheim, Shlomit Wizel, Greta Sterimbaum, Ehud Amir
  • Novel crystalline forms of gatifloxacin
    Publication number: 20050288301
    Abstract: Provided are novel crystalline forms of gatifloxacin denominated forms A, B, C, D, E1, F, G, H, I, and J, and methods for their preparation. Also provided are methods for making known crystalline forms of gatifloxacin, in particular forms omega and T2RP.
    Type: Application
    Filed: August 19, 2005
    Publication date: December 29, 2005
    Inventors: Valerie Niddam-Hildesheim, Shlomit Wizel, Greta Sterimbaum, Ehud Amir
  • Crystalline forms of fexofenadine hydrochloride and processes for their preparation
    Publication number: 20050256163
    Abstract: Provided are crystalline forms of fexofenadine hydrochloride and processes for their preparation.
    Type: Application
    Filed: April 26, 2005
    Publication date: November 17, 2005
    Inventors: Ilan Kor, Shlomit Wizel
  • Preparation of levofloxacin and forms thereof
    Publication number: 20050222409
    Abstract: Levofloxacin was prepared by reacting (S)-(?)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid with N-methyl piperazine in a polar solvent or in a neat mixture to form levofloxacin. Further processing of the levofloxacin produced novel levofloxacin forms, including a hemihydrate and Forms A, B, C, F, G and H.
    Type: Application
    Filed: May 26, 2005
    Publication date: October 6, 2005
    Inventors: Valerie Niddam-Hildesheim, Neomi Gershon, Ehud Amir, Shlomit Wizel
  • Crystalline forms of valacyclovir hydrochloride
    Publication number: 20050187229
    Abstract: Provided are novel polymorphs and pseudopolymorphs of valacyclovir hydrochloride and pharmaceutical compositions containing these. Also provided are methods for making the novel polymorphs and pseudopolymorphs, which include valacyclovir hydrochloride monohydrate and valacyclovir hydrochloride dihydrate.
    Type: Application
    Filed: January 25, 2005
    Publication date: August 25, 2005
    Inventors: Shlomit Wizel, Judith Aronhime, Valerie Niddam-Hildesheim, Ben-Zion Dolitzky, Marina Etinger, Michael Yuzefovich, Gennady Nisnevich, Boris Pertsikov, Boris Tishin, Dina Blasberger
  • Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
    Patent number: 6924393
    Abstract: The present invention relates to novel essentially pure venlafaxine and the process of preparation thereof. The present invention also relates to novel solvate forms of venlafaxine hydrochloride and the process of preparation thereof. Furthermore, the present invention provides a novel process for preparing venlafaxine hydrochloride from venlafaxine; the process comprises the steps of: i) preparing a mixture of venlafaxine with acetone; and ii) exposing the mixture in gaseous hydrochloric acid.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: August 2, 2005
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel, Gannady A. Nisnevich