Patents by Inventor Shmuel Bukshpan

Shmuel Bukshpan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11951135
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating muscle diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: April 9, 2024
    Assignee: Minovia Therapeutics Ltd.
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • Publication number: 20230381227
    Abstract: The present invention relates to products and methods for treatment of hair loss. Specifically, the present application relates to compositions and methods for prevention and treatment of hair loss, comprising administration of a composition comprising intact mitochondria, ruptured mitochondria and/or mitochondrial constituents.
    Type: Application
    Filed: August 8, 2023
    Publication date: November 30, 2023
    Inventors: Natalie YIVGI-OHANA, Uriel Halavee, Shmuel Bukshpan
  • Publication number: 20210322485
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, and therapeutic methods utilizing such cells for the alleviation of debilitating conditions, including aging, and age-related diseases as well as the debilitating effects of anti-cancer therapies in subjects in need thereof.
    Type: Application
    Filed: July 22, 2019
    Publication date: October 21, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher
  • Publication number: 20210290691
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating muscle diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: September 23, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • Publication number: 20210275599
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating brain diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: September 9, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • Publication number: 20210275597
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating ocular diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: September 9, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • Publication number: 20210275587
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating renal diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: September 9, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Moriya Blumkin, Noa Sher
  • Publication number: 20210260137
    Abstract: The present invention provides human stem cells enriched with functional mitochondria, wherein the healthy functional exogenous mitochondria constitute at least 3% and less than 33% of the total mitochondria in the mitochondrially-enriched human stem cells. Further disclosed are methods for the production of such cells, and uses thereof for the treatment of primary mitochondrial diseases.
    Type: Application
    Filed: July 22, 2019
    Publication date: August 26, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • Publication number: 20210252075
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating liver diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: August 19, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • Publication number: 20210228642
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating pancreatic diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: July 29, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • Publication number: 20210205368
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating renal diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: March 19, 2021
    Publication date: July 8, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Moriya Blumkin, Noa Sher
  • Publication number: 20210023143
    Abstract: The present invention relates to methods of using compositions comprising intact mitochondria and/or ruptured mitochondria for elevating lipid metabolism in cells. The present invention further provides methods for treating diseases which benefit from elevation of lipid and cholesterol metabolism and methods for inducing weight loss or reducing weight gain comprising administering compositions comprising intact mitochondria and/or ruptured mitochondria to a subject in need thereof.
    Type: Application
    Filed: March 26, 2019
    Publication date: January 28, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan
  • Patent number: 10702556
    Abstract: The present invention relates to compositions and methods of inducing angiogenesis and methods of treating a pathology that would benefit from angiogenesis by use of a composition comprising partially purified intact mitochondria and/or ruptured mitochondria derived therefrom.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: July 7, 2020
    Assignee: Minovia Therpautices Ltd.
    Inventors: Natalie Yivgi-Ohana, Uriel Halavee, Shmuel Bukshpan
  • Publication number: 20200023005
    Abstract: The present invention relates to products and methods for treatment of hair loss. Specifically, the present application relates to compositions and methods for prevention and treatment of hair loss, comprising administration of a composition comprising intact mitochondria, ruptured mitochondria and/or mitochondrial constituents.
    Type: Application
    Filed: March 22, 2018
    Publication date: January 23, 2020
    Inventors: Natalie YIVGI-OHANA, Uriel HALAVEE, Shmuel BUKSHPAN
  • Patent number: 10325379
    Abstract: A biometric device that may include a sensor that reacts to a chemical element associated with a sweat gland; wherein when the sensor is contacted by an area of a skin of a person, an image that comprises information about locations of sweat glands within the area of the skin of the person is generated by the sensor; an image processor that is configured to generate an authentication result by comparing between (a) the information of the image generated by the sensor and (b) reference information of locations of sweat glands of a given person; wherein the authentication result indicates whether the person is the given person; and a communication module for communicating an authentication result indication.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: June 18, 2019
    Inventors: Shmuel Bukshpan, Uriel Halavee, Arie Heiman
  • Publication number: 20170116492
    Abstract: A biometric device that may include a sensor that reacts to a chemical element associated with a sweat gland; wherein when the sensor is contacted by an area of a skin of a person, an image that comprises information about locations of sweat glands within the area of the skin of the person is generated by the sensor; an image processor that is configured to generate an authentication result by comparing between (a) the information of the image generated by the sensor and (b) reference information of locations of sweat glands of a given person; wherein the authentication result indicates whether the person is the given person; and a communication module for communicating an authentication result indication
    Type: Application
    Filed: September 14, 2016
    Publication date: April 27, 2017
    Inventors: Shmuel Bukshpan, Uriel Halavee, Arie Heiman
  • Publication number: 20170027482
    Abstract: A wireless colorimetric sensor for detecting, quantifying, or both detecting and quantifying, at least one analyte in a sample, the sensor including a light transparent chemochromic layer applied onto the photoactive surface of an image sensor, or attached thereto via an optic coupler, wherein the chemochromic layer comprises a chemochromic material that is optically altered when contacted with the analyte. A method for detecting at least one analyte with a colorimetric sensor.
    Type: Application
    Filed: April 2, 2015
    Publication date: February 2, 2017
    Inventors: Gleb ZILBERSTEIN, Shmuel BUKSHPAN
  • Publication number: 20150260656
    Abstract: Disclosed is a method for detecting at least one analyte in a sample, which comprises applying a variable optical filter, comprising a chemochromic material that is sensitive to the analyte, to an optical lens of a camera, an optical lens of a multi-cell photosensor and/or to a multi-cell photosensor, contacting at least part of the chemochromic material with the sample, exposing at least part of the variable optical filter to electromagnetic radiation after at least part of the chemochromic material was exposed to the sample to obtain digital data regarding the chemochromic material that was contacted with the sample and processing the digital data and comparing said digital data with a reference.
    Type: Application
    Filed: October 22, 2013
    Publication date: September 17, 2015
    Applicant: SPECTROPHON LTD.
    Inventors: Gleb Zilberstein, Shmuel Bukshpan
  • Publication number: 20150079193
    Abstract: The present invention relates to compositions and methods of inducing angiogenesis and methods of treating a pathology that would benefit from angiogenesis by use of a composition comprising partially purified intact mitochondria and/or ruptured mitochondria derived therefrom.
    Type: Application
    Filed: May 16, 2013
    Publication date: March 19, 2015
    Inventors: Natalie Yivgi-Ohana, Uriel Halavee, Shmuel Bukshpan
  • Publication number: 20150024017
    Abstract: A solid buffer including one or more ion exchange materials, wherein said solid buffer has a volumetric buffering capacity greater than about 20 mM H+/(L·pH unit) and further wherein, when said material is in an environment capable of transporting H+ ions, said solid buffer is adapted to cause the death of at least one target cell within or in contact with said environment. A selectively permeable barrier layer may be provided covering the solid buffer.
    Type: Application
    Filed: April 11, 2014
    Publication date: January 22, 2015
    Applicant: OPLON PURE SCIENCE, LTD.
    Inventors: Shmuel BUKSHPAN, Gleb ZILBERSTEIN