Patents by Inventor Shohei Koide

Shohei Koide has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10344091
    Abstract: Disclosed herein are anti-Galectin-9 antibodies and methods of using such for inhibiting a signaling pathway mediated by Galectin-9 or eliminating pathologic cells expressing Galectin-9. Such anti-Galectin-9 antibodies may also be used to diagnose and/or to treat diseases associated with Galectin-9, such as autoimmune diseases and solid tumors.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: July 9, 2019
    Assignees: New York University, PureTech Health, LLC
    Inventors: Shohei Koide, George Miller, Akiko Koide, Linxiao Chen, Eric Elenko, Aleksandra Filipovic, Joseph Bolen
  • Publication number: 20190144540
    Abstract: Disclosed herein are antibodies specific to a delta1 chain of a ?? T cell receptor and methods of using such for modulating ?? T cell bioactivity. Such anti-Delta1 antibodies may also be used to treat diseases associated with ?? T cell activation, such as solid tumors, or for detecting presence of ??1 T cells.
    Type: Application
    Filed: January 23, 2019
    Publication date: May 16, 2019
    Inventors: Shohei Koide, George Miller, Akiko Koide, Tatyana Panchenko
  • Publication number: 20190127472
    Abstract: Disclosed herein are anti-Galectin-9 antibodies and methods of using such for inhibiting a signaling pathway mediated by Galectin-9 or eliminating pathologic cells expressing Galectin-9. Such anti-Galectin-9 antibodies may also be used to diagnose and/or to treat diseases associated with Galectin-9, such as autoimmune diseases and solid tumors.
    Type: Application
    Filed: October 29, 2018
    Publication date: May 2, 2019
    Inventors: Shohei Koide, George Miller, Akiko Koide, Linxiao Chen, Eric Elenko, Aleksandra Filipovic, Joseph Bolen
  • Patent number: 10252529
    Abstract: There is provided a printer including first to fourth head chips, and first and second rollers. The first to fourth head chips are arranged at intervals in a second direction orthogonal to a first direction. A nozzle, of nozzles arranged in a second head chip N and used for printing, which is positioned closest to the one side in the second direction is referred to as a nozzle A. A nozzle, of nozzles arranged in a fourth head chip N and used for printing, which is positioned closest to the one side in the second direction is referred to as a nozzle B. The nozzle A is arranged closer to the one side in the second direction than the nozzle B and the first roller is arranged closer to the other side in the second direction than the second roller.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: April 9, 2019
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Keita Hirai, Shohei Koide
  • Patent number: 10208110
    Abstract: Embodiments concern compositions and methods involving recombinant antibodies to histone post-translational modifications. The invention provides compositions and methods for histone methyltransferase assays. In certain embodiments, the compositions and methods involve a recombinant antibody that binds histone H3 fragment harboring biomarkers such as H3K9me3 mark, H3K4me3 mark, H3K36me3 mark, H3K27me3, H3K9me3 and H3S10phos or a recombinant antibody that binds histone H4 fragment harboring H4K20me3 mark.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: February 19, 2019
    Assignee: The University of Chicago
    Inventors: Takamitsu Hattori, Shohei Koide, Joseph Taft, Akiko Koide
  • Publication number: 20190030892
    Abstract: A liquid discharge apparatus is provided, including a liquid discharge head including: an upper substrate, a plurality of piezoelectric elements, an intermediate substrate, a lower substrate and a plurality of individual traces arranged on the upper substrate and extending toward the contacts arranged on the one end side in the second direction from the plurality of piezoelectric elements respectively.
    Type: Application
    Filed: August 3, 2018
    Publication date: January 31, 2019
    Inventors: Kyohei Naito, Shohei Koide, Jiro Yamamoto
  • Patent number: 10189266
    Abstract: A liquid ejection apparatus is disclosed. One apparatus includes a nozzle through which fluid is ejected or purged, and a pressure regulating valve arranged upstream of the nozzle. The pressure regulating valve is configured to open in response to an open/close pressure differential of the fluid across the pressure regulating valve. The pressure regulating valve is configured to controllably regulate the open/close pressure differential. The apparatus further includes a controller configured to, when a suction pump is being operated to perform a first purging operation comprising creating a first negative pressure through suctioning by the suction pump to purge the fluid through the nozzle, control the pressure regulating valve to set the open/close pressure differential of the pressure regulating valve to a first value.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: January 29, 2019
    Assignee: BROTHER KOGYO KABUSHIKI KAISHA
    Inventor: Shohei Koide
  • Publication number: 20180346551
    Abstract: The present invention provides a fibronectin type III (Fn3) molecule, wherein the Fn3 contains a stabilizing mutation. The present invention also provides Fn3 polypeptide monobodies, nucleic acid molecules encoding monobodies, and variegated nucleic acid libraries encoding such monobodies. Also provided are methods of preparing a Fn3 polypeptide monobody, and kits to perform the methods.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 6, 2018
    Applicant: Research Corporation Technologies, Inc.
    Inventor: Shohei Koide
  • Patent number: 10052872
    Abstract: A liquid discharge apparatus is provided, including a liquid discharge head including: an upper substrate, a plurality of piezoelectric elements, an intermediate substrate, a lower substrate and a plurality of individual traces arranged on the upper substrate and extending toward the contacts arranged on the one end side in the second direction from the plurality of piezoelectric elements respectively.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: August 21, 2018
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Kyohei Naito, Shohei Koide, Jiro Yamamoto
  • Publication number: 20180208678
    Abstract: Aspects of the disclosure relate to compositions of enzyme-binding polypeptides (EBPs) that modify the substrate specificity of an enzyme and a method for identifying an EBP that modifies substrate specificity of an enzyme binding at least one substrate, the method comprising: contacting the enzyme with a polypeptide library comprising a plurality of EBPs that bind different epitopes of the enzyme; identifying EBPs that bind to the enzyme to form an EBP-enzyme complex; assaying for the activity level and substrate specificity of the EBP-enzyme complex; and identifying EBPs that modify the substrate specificity of the enzyme by identifying EBPs that, when in an EBP-enzyme complex, have a different substrate specificity than un-complexed EBP; wherein the catalytic rate constant of the EBP-enzyme complex is ?50% of the un-complexed enzyme for at least one substrate and/or wherein the EBP-enzyme complex retains binding to a substrate.
    Type: Application
    Filed: July 15, 2016
    Publication date: July 26, 2018
    Inventors: Shohei Koide, Shun-Ichi Tanaka, Akiko Koide
  • Publication number: 20180194137
    Abstract: There is provided a printer including first to fourth head chips, and first and second rollers. The first to fourth head chips are arranged at intervals in a second direction orthogonal to a first direction. A nozzle, of nozzles arranged in a second head chip N and used for printing, which is positioned closest to the one side in the second direction is referred to as a nozzle A. A nozzle, of nozzles arranged in a fourth head chip N and used for printing, which is positioned closest to the one side in the second direction is referred to as a nozzle B. The nozzle A is arranged closer to the one side in the second direction than the nozzle B and the first roller is arranged closer to the other side in the second direction than the second roller.
    Type: Application
    Filed: December 12, 2017
    Publication date: July 12, 2018
    Inventors: Keita HIRAI, Shohei KOIDE
  • Patent number: 9950538
    Abstract: A liquid ejecting head, including a flow-path unit that includes: first and second nozzle groups disposed alongside each other in a second direction orthogonal to a first direction in which nozzles are arranged; first and second common liquid chambers respectively communicating with the first and second nozzle groups, the first and second common liquid chambers being disposed alongside each other in the second direction; a liquid supply opening communicating with the first common liquid chamber and a liquid discharge opening communicating with the second common liquid chamber, on one side of the flow-path unit in the first direction; and a connecting path connecting the first and second common liquid chambers on the other side of the flow-path unit in the first direction, wherein the first common liquid chamber is disposed nearer to an outer periphery of the flow-path unit in the second direction than the second common liquid chamber.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: April 24, 2018
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Hiroto Sugahara, Shohei Koide, Taisuke Mizuno
  • Patent number: 9950529
    Abstract: There is provided an ink jet printer including a carriage, and an ink jet head. The ink jet head has two first nozzle groups to jet a first ink, two second nozzle groups to jet a second ink, and two third nozzle groups to jet the second ink. Each of the first, second and third nozzle groups includes a plurality of nozzles arrayed at a pitch P along a second direction. The second nozzle groups accord respectively with the first nozzle groups in terms of nozzle position in the second direction, the third nozzle groups are dislocated respectively from the second nozzle groups in terms of nozzle position in the second direction, and any two groups selected from the first and second nozzle groups are arranged respectively on two opposite sides of each of the third nozzle groups in the first direction.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: April 24, 2018
    Assignee: BROTHER KOGYO KABUSHIKI KAISHA
    Inventors: Shohei Koide, Atsushi Ito
  • Patent number: 9885050
    Abstract: The invention provides a molecular affinity clamp. The architecture of the affinity clamp is modular with two biorecognition modules, each capable of binding a target motif. The first biorecognition module has a recognition domain that possesses inherent or natural specificity for the target motif. The second biorecognition module also has a recognition domain that binds the motif. The two biorecognition modules are tethered together either directly, e.g., via a peptide bond between the two modules, or indirectly, e.g., via a linker moiety or linker.
    Type: Grant
    Filed: November 10, 2008
    Date of Patent: February 6, 2018
    Assignee: The University of Chicago
    Inventors: Shohei Koide, Akiko Koide, Jin Huang
  • Publication number: 20180015724
    Abstract: A liquid discharge apparatus is provided, including a liquid discharge head including: an upper substrate, a plurality of piezoelectric elements, an intermediate substrate, a lower substrate and a plurality of individual traces arranged on the upper substrate and extending toward the contacts arranged on the one end side in the second direction from the plurality of piezoelectric elements respectively.
    Type: Application
    Filed: June 26, 2017
    Publication date: January 18, 2018
    Inventors: Kyohei Naito, Shohei Koide, Jiro Yamamoto
  • Patent number: 9868285
    Abstract: There is provided a printer including first to fourth head chips, and first and second rollers. The first to fourth head chips are arranged at intervals in a second direction orthogonal to a first direction. A nozzle, of nozzles arranged in a second head chip N and used for printing, which is positioned closest to the one side in the second direction is referred to as a nozzle A. A nozzle, of nozzles arranged in a fourth head chip N and used for printing, which is positioned closest to the one side in the second direction is referred to as a nozzle B. The nozzle A is arranged closer to the one side in the second direction than the nozzle B and the first roller is arranged closer to the other side in the second direction than the second roller.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: January 16, 2018
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Keita Hirai, Shohei Koide
  • Publication number: 20170369555
    Abstract: The present invention provides a fibronectin type III (Fn3) molecule, wherein the Fn3 contains a stabilizing mutation. The present invention also provides Fn3 polypeptide monobodies, nucleic acid molecules encoding monobodies, and variegated nucleic acid libraries encoding such monobodies. Also provided are methods of preparing a Fn3 polypeptide monobody, and kits to perform the methods.
    Type: Application
    Filed: February 16, 2016
    Publication date: December 28, 2017
    Applicant: Research Corporation Technologies, Inc.
    Inventor: Shohei Koide
  • Patent number: 9809023
    Abstract: A liquid ejecting device, including: a flow-path defining member having a pressure chamber formed therein; a piezoelectric actuator constituted by a plurality of layers which includes a piezoelectric layer, a common electrode, and an individual electrode, superposed on the flow-path defining member, and having a through-hole communicating with the pressure chamber; an annular conductor disposed on one of opposite surfaces of the piezoelectric actuator remote from the flow-path defining member such that a part of the layers are sandwiched between the annular conductor and the common electrode, the annular conductor surrounding a periphery of the through-hole; and a liquid supply member having a supply path communicating with the through-hole and bonded to the one of the opposite surfaces via the annular conductor, wherein the annular conductor is connected to a terminal configured to be given a predetermined constant potential and is exposed to a flow path defined by the through-hole.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: November 7, 2017
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Shohei Koide, Keita Hirai
  • Publication number: 20170282587
    Abstract: A liquid ejection apparatus is disclosed. One apparatus includes a nozzle through which fluid is ejected or purged, and a pressure regulating valve arranged upstream of the nozzle. The pressure regulating valve is configured to open in response to an open/close pressure differential of the fluid across the pressure regulating valve. The pressure regulating valve is configured to controllably regulate the open/close pressure differential. The apparatus further includes a controller configured to, when a suction pump is being operated to perform a first purging operation comprising creating a first negative pressure through suctioning by the suction pump to purge the fluid through the nozzle, control the pressure regulating valve to set the open/close pressure differential of the pressure regulating valve to a first value.
    Type: Application
    Filed: March 21, 2017
    Publication date: October 5, 2017
    Inventor: Shohei KOIDE
  • Publication number: 20170282560
    Abstract: There is provided a printer including first to fourth head chips, and first and second rollers. The first to fourth head chips are arranged at intervals in a second direction orthogonal to a first direction. A nozzle, of nozzles arranged in a second head chip N and used for printing, which is positioned closest to the one side in the second direction is referred to as a nozzle A. A nozzle, of nozzles arranged in a fourth head chip N and used for printing, which is positioned closest to the one side in the second direction is referred to as a nozzle B. The nozzle A is arranged closer to the one side in the second direction than the nozzle B and the first roller is arranged closer to the other side in the second direction than the second roller.
    Type: Application
    Filed: February 7, 2017
    Publication date: October 5, 2017
    Inventors: Keita HIRAI, Shohei KOIDE