Patents by Inventor Shoji Takeuchi

Shoji Takeuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140010960
    Abstract: A method of producing a microstructured gel in a shape in accordance with a pattern comprises: dropping a polymerizable monomer aqueous solution containing a polymerizable monomer component onto a portion of a surface of a substrate having a pattern comprising a fine groove in the surface; moving by capillary action the polymerizable monomer aqueous solution along the groove constituting the pattern; and subjecting the polymerizable monomer aqueous solution in the groove to polymerization.
    Type: Application
    Filed: January 6, 2012
    Publication date: January 9, 2014
    Applicants: THE UNIVERSITY OF TOKYO, TERUMO KABUSHIKI KAISHA
    Inventors: Hideaki Shibata, Shoji Takeuchi, Yun-Jung Heo
  • Publication number: 20130267800
    Abstract: To provide a fluorescent hydrogel having superior detectability of saccharides such as glucose and minimal invasiveness, a method for producing the same, and a sensor for measuring saccharides using the same. A florescent hydrogel having a structure represented by the following chemical formula 1, a method for producing the same, and a sensor for measuring saccharides using the same.
    Type: Application
    Filed: September 7, 2011
    Publication date: October 10, 2013
    Applicants: THE UNIVERSITY OF TOKYO, TERUMO KABUSHIKI KAISHA
    Inventors: Yun-Jung Heo, Hideaki Shibata, Tetsuro Kawanishi, Shoji Takeuchi, Yukiko Matsunaga, Teru Okitsu
  • Patent number: 8513165
    Abstract: There is provided a planar lipid bilayer array formed by microfluidic technique and a method of analysis using the planar lipid bilayers, providing the advantages such as portability, decreased analysis time, a smaller amount of required reagents, and parallel automation with high reproducibility. The planar lipid bilayer array formed by microfluidic technique is a planar lipid bilayer array formed by microfluidic technique (PDMS device) 1 saturated with water by preliminarily immersing in water, comprising microchannels 2 connected to an inlet of a microfluidic channel and arranged in parallel, and microchambers 3 having apertures on both sides of the microchannel 2.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: August 20, 2013
    Assignee: The University of Tokyo
    Inventors: Shoji Takeuchi, Hiroaki Suzuki, Sadao Ota, Wei-Heong Tan
  • Patent number: 8506905
    Abstract: The present invention provides simple and an accurate apparatuses for forming bilayer membranes by the contact of amphipathic monolayers. In one apparatus, amphipathic monolayers are brought into contact and fused by controlling the pressure of liquids introduced from microchannels forming an intersection containing a chamber. In another apparatus, the chamber includes a number of compartments and at least one construction portion. In this apparatus, a droplet is formed within each compartment and contact of amphipatic monolayers is accomplished by adjusting the size of the droplets.
    Type: Grant
    Filed: July 26, 2006
    Date of Patent: August 13, 2013
    Assignee: The University of Tokyo
    Inventors: Shoji Takeuchi, Hiroaki Suzuki, Kei Funakoshi
  • Publication number: 20130165348
    Abstract: Provided are a method and a device for synthesizing proteins from DNA molecules captured in microchambers, whereby the distance between microchambers can be shortened, thereby allowing the density of arrays to be increased. Microchambers (32) are arranged at a high density. A DNA solution (34) which has been diluted so as to capture one DNA molecule on average is enclosed in the microchambers (32). Then, mRNA is synthesized using one DNA molecule on average as a template. Based on this mRNA, a protein (37) is extracellularly synthesized.
    Type: Application
    Filed: December 8, 2010
    Publication date: June 27, 2013
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Teruo Fujii, Soo-Hyeon Kim, Shoji Takeuchi, Dominique Fourmy, Satoko Yoshizawa
  • Publication number: 20130136863
    Abstract: A method for fabricating a microarray of plural soft materials includes: vapor-depositing a first layer poly(para-xylylene) resin on a substrate, forming a first micro pattern in the poly(para-xylylene) resin; obtaining a substrate including a first microarray formed by pouring a first soft material solution, freeze-drying the first soft material to obtain a micro-arrayed substrate of the freeze-dried first soft material; vapor-depositing a second layer poly(para-xylylene) resin on the micro-arrayed substrate of the freeze-dried first soft material, forming a second micro pattern placed differently from the first micro pattern by penetrating the poly(para-xylylene) resin of the first and second layers, forming a second microarray on the substrate by pouring a second soft material solution; and forming a microarray of the first and second soft materials on the substrate by peeling off the poly(para-xylylene) resin of the first and second layers.
    Type: Application
    Filed: March 27, 2012
    Publication date: May 30, 2013
    Applicant: NTT DOCOMO, INC.
    Inventors: Satoshi Hiyama, Kaori Kuribayashi, Hiroaki Onoe, Shoji Takeuchi
  • Publication number: 20130071948
    Abstract: A method for preparing a linearly extended supramolecular fiber or a plurality of linearly aligned supramolecular fibers, which comprises the step of allowing supramolecular monomers to be self-assembled in a microfluidic channel.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 21, 2013
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Shoji Takeuchi, Hiroaki Onoe, Daisuke Kiriya, Itaru Hamachi, Masato Ikeda
  • Patent number: 8398866
    Abstract: A microchip for forming an emulsion has a first glass substrate, a second glass substrate and a silicon substrate. The silicon substrate has formed therein a first fluid flow path through which a first fluid flows and a second fluid flow path through which a second fluid that is not mixed with the first fluid flows. The first fluid flow path has a plurality of branched flow paths that join at a joint portion. The second fluid flow path communicates with the joint portion. The silicon substrate has formed therein an emulsion formation flow path that faces an edge portion of the second fluid flow path at the joint portion. An emulsion composed of the first fluid and the second fluid that is surrounded by the first fluid is formed in the emulsion formation flow path.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: March 19, 2013
    Assignee: Dai Nippon Printing Co., Ltd.
    Inventors: Yutaka Ozawa, Ryoichi Ohigashi, Koji Fujimoto, Shoji Takeuchi
  • Patent number: 8367135
    Abstract: An ice-candy forming container is provided which produces ice-candies having a complicated shape copying the face of a cartoon character or the like with higher quality and without a loss in shape. A forming container includes a first mold having a pattern portion formed in one face thereof, and a second mold configured to slide over and along the one face of the first mold, in a close contact relation, in directions designated by arrows A1-A2, so as to contain the first mold therein. In such a containing position, the second mold contacts externally and closely substantially an entire surface of the outer periphery of the pattern portion.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: February 5, 2013
    Assignee: Zensho Co., Ltd.
    Inventor: Shoji Takeuchi
  • Publication number: 20120301963
    Abstract: A microfiber showing improved mechanical strength, which comprises a micro gel fiber consisting of collagen gel or the like covered with high strength hydrogel such as alginate gel.
    Type: Application
    Filed: October 12, 2010
    Publication date: November 29, 2012
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Shoji Takeuchi, Hiroaki Onoe, Yukiko Matsunaga, Daisuke Kiriya, Riho Gojo, Midori Negishi
  • Publication number: 20120248062
    Abstract: A microchip for forming an emulsion has a first glass substrate, a second glass substrate and a silicon substrate. The silicon substrate has formed therein a first fluid flow path through which a first fluid flows and a second fluid flow path through which a second fluid that is not mixed with the first fluid flows. The first fluid flow path has a plurality of branched flow paths that join at a joint portion. The second fluid flow path communicates with the joint portion. The silicon substrate has formed therein an emulsion formation flow path that faces an edge portion of the second fluid flow path at the joint portion. An emulsion composed of the first fluid and the second fluid that is surrounded by the first fluid is formed in the emulsion formation flow path.
    Type: Application
    Filed: June 18, 2012
    Publication date: October 4, 2012
    Applicant: Dai Nippon Printing Co., Ltd.
    Inventors: Yutaka OZAWA, Ryoichi OHIGASHI, Koji FUJIMOTO, Shoji TAKEUCHI
  • Patent number: 8263152
    Abstract: An ice-candy forming container is provided which produces ice-candies having a complicated shape copying the face of a cartoon character or the like with higher quality and without a loss in shape. A forming container includes a first mold having a pattern portion formed in one face thereof, and a second mold configured to slide over and along the one face of the first mold, in a close contact relation, in directions designated by arrows A1-A2, so as to contain the first mold therein. In such a containing position, the second mold contacts externally and closely substantially an entire surface of the outer periphery of the pattern portion.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: September 11, 2012
    Assignee: Zensho Co., Ltd.
    Inventor: Shoji Takeuchi
  • Patent number: 8231265
    Abstract: A microchip for forming an emulsion has a first glass substrate, a second glass substrate and a silicon substrate. The silicon substrate has formed therein a first fluid flow path through which a first fluid flows and a second fluid flow path through which a second fluid that is not mixed with the first fluid flows. The first fluid flow path has a plurality of branched flow paths that join at a joint portion. The second fluid flow path communicates with the joint portion. The silicon substrate has formed therein an emulsion formation flow path that faces an edge portion of the second fluid flow path at the joint portion. An emulsion composed of the first fluid and the second fluid that is surrounded by the first fluid is formed in the emulsion formation flow path.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: July 31, 2012
    Assignee: Dai Nippon Printing Co., Ltd.
    Inventors: Yutaka Ozawa, Ryoichi Ohigashi, Koji Fujimoto, Shoji Takeuchi
  • Publication number: 20120183989
    Abstract: A method for culturing hepatocytes, wherein hepatocytes embedded in an extracellular matrix is placed on a gas-permeable membrane and the hepatocytes are cultured while being supplied with oxygen from the gas-permeable membrane side. By this, the polarity in the hepatocytes can be induced and a bile canaliculus can be formed in a short period of time. Further, the formed polarity can be maintained for a longer period.
    Type: Application
    Filed: July 28, 2010
    Publication date: July 19, 2012
    Inventors: Hitoshi Matsui, Yasuyuki Sakai, Teruo Fujii, Shoji Takeuchi, Yukiko Tsuda
  • Publication number: 20120070873
    Abstract: An object is to move a rail molecule by means of a biomolecular motor deposited on a base and inactivate the biomolecular motor through irradiation with light having a predetermined wavelength, to thereby readily and reliably fix the rail molecule at a predetermined position, while orienting the rail molecule in a predetermined direction without employment of any reagent. A method for fixing a rail molecule which has polarity and on which a biomolecular motor moves in a direction corresponding to the polarity includes depositing a biomolecular motor on a base; moving a rail molecule by means of the biomolecular motor; and inactivating the biomolecular motor by irradiating the biomolecular motor with light having a predetermined wavelength when the rail molecule reaches a predetermined position, to thereby fix the rail molecule so that it is oriented in a predetermined direction.
    Type: Application
    Filed: November 30, 2011
    Publication date: March 22, 2012
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Hiroyuki Fujita, Shoji Takeuchi, Ryuji Yokokawa
  • Patent number: 8088739
    Abstract: An object is to move a rail molecule by means of a biomolecular motor deposited on a base and inactivate the biomolecular motor through irradiation with light having a predetermined wavelength, to thereby readily and reliably fix the rail molecule at a predetermined position, while orienting the rail molecule in a predetermined direction without employment of any reagent. A method for fixing a rail molecule which has polarity and on which a biomolecular motor moves in a direction corresponding to the polarity includes depositing a biomolecular motor on a base; moving a rail molecule by means of the biomolecular motor; and inactivating the biomolecular motor by irradiating the biomolecular motor with light having a predetermined wavelength when the rail molecule reaches a predetermined position, to thereby fix the rail molecule so that it is oriented in a predetermined direction.
    Type: Grant
    Filed: November 21, 2005
    Date of Patent: January 3, 2012
    Assignee: The University of Tokyo
    Inventors: Hiroyuki Fujita, Shoji Takeuchi, Ryuji Yokokawa
  • Publication number: 20110306110
    Abstract: A method for preparing a biomaterial comprising a gel layer which forms a core region, and cells (cover cells) which cover around the gel layer, said method comprising the steps of: (a) bringing a biocompatible oil or a vegetable oil or a mixture thereof with a mineral oil into contact with a solution containing a gel-forming component to form monodisperse droplets; (b) inducing gelation of the monodisperse droplets to give gel beads; and (c) seeding the cover cells over the surface of the gel beads.
    Type: Application
    Filed: December 14, 2009
    Publication date: December 15, 2011
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Shoji Takeuchi, Yukiko Matsunaga, Yuya Morimoto
  • Patent number: 8039247
    Abstract: To provide a method of forming a planar lipid-bilayer membrane for membrane protein analysis, by which downsizing, simplifying, and multichanneling of a device therefore are achieved. A planar lipid-bilayer membrane 24 is formed by filling a microchannel 12 with a buffer solution 18, the microchannel 12 disposed under a horizontal partition wall 13 having an aperture 14; applying a small amount of a lipid solution 20 as a droplet on the aperture 14 filled with the buffer solution 18 to thereby form a thin layer 21 of the lipid solution in a chamber, the chamber 17 being formed at a position corresponding to the aperture 14 and provided with a liquid trap 15 inside the chamber; and applying a buffer solution 23 as a droplet to the chamber 17 from the upper side of the chamber.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: October 18, 2011
    Assignee: Japan Science and Technology Agency
    Inventors: Shoji Takeuchi, Hiroaki Suzuki, Hiroyuki Noji
  • Publication number: 20110165297
    Abstract: An ice-candy forming container is provided which produces ice-candies having a complicated shape copying the face of a cartoon character or the like with higher quality and without a loss in shape. A forming container includes a first mold having a pattern portion formed in one face thereof, and a second mold configured to slide over and along the one face of the first mold, in a close contact relation, in directions designated by arrows A1-A2, so as to contain the first mold therein. In such a containing position, the second mold contacts externally and closely substantially an entire surface of the outer periphery of the pattern portion.
    Type: Application
    Filed: March 15, 2011
    Publication date: July 7, 2011
    Applicant: Zensho Co., Ltd.
    Inventor: Shoji TAKEUCHI
  • Publication number: 20110165296
    Abstract: An ice-candy forming container is provided which produces ice-candies having a complicated shape copying the face of a cartoon character or the like with higher quality and without a loss in shape. A forming container includes a first mold having a pattern portion formed in one face thereof, and a second mold configured to slide over and along the one face of the first mold, in a close contact relation, in directions designated by arrows A1-A2, so as to contain the first mold therein. In such a containing position, the second mold contacts externally and closely substantially an entire surface of the outer periphery of the pattern portion.
    Type: Application
    Filed: March 15, 2011
    Publication date: July 7, 2011
    Applicant: Zensho Co., Ltd.
    Inventor: Shoji TAKEUCHI