Abstract: A shape-data acquisition apparatus obtains shape data of a work surface and includes an illuminator, a transmissive optical element, and an imager. The illuminator has a luminance distribution of a first cycle to irradiate the work surface. The transmissive optical element faces specular reflected light reflected by the work surface and has a transmittance distribution of a second cycle. The imager receives the specular reflected light to capture the work surface. The cyclic directions of the first cycle and the second cycle folded at a mirror image position on the work surface are parallel to each other. A relation of b=a×f2/f1 is satisfied when a is a distance between the illuminator and the work surface, b is a distance between the work surface and the transmissive optical element, f1 is the first cycle, and f2 is the second cycle.

Abstract: It is intended to provide an antitumor drug having an excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. There is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-TROP2 antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-(CH2)n2-C(?O)— wherein the anti-TROP2 antibody is connected to the terminal of L1, and the antitumor compound is connected to the carbonyl group of the —(CH2)n2-C(?O)— moiety with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: It is intended to provide an antitumor drug having an excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. There is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-TROP2 antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-(CH2)n2-C(?O)— wherein the anti-TROP2 antibody is connected to the terminal of L1, and the antitumor compound is connected to the carbonyl group of the —(CH2)n2-C(?O)— moiety with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: A content evaluation device includes a usage trend storage unit that stores, for each user, trend information indicating a usage trend in each time period and for each content type, a score calculation unit that calculates a recommendation score for each content, a classification unit that clusters a group of users having similar trend information on the basis of the trend information of each user, a derivation unit that derives overall trend information from the trend information of affiliated users belonging to the clustered group of users, a score adjustment unit that adjusts the recommendation score of each content in reflection of the overall trend information in a target time period to a recommendation score for each content, and a determination unit that determines content to recommend to the target user in the target time period on the basis of the adjusted recommendation score of each content.

Abstract: A distance-measuring apparatus, a mobile object, a robot, a three-dimensional measuring device, a surveillance camera, and a distance-measuring method. The distance-measuring apparatus, a mobile object includes a light source to emit light, an imaging element to receive and photoelectrically convert the light into a plurality of electrical signals, and to obtain the electrical signals upon being sorted into a plurality of phase signals, and a computing unit to calculate distance to the object based on the phase signals. In the distance-measuring apparatus, a period of time during which the imaging element obtains the phase signals is different from a light emitting period of the light source in length. The distance-measuring method includes determining whether or not aliasing is present based on a light emitting period of the light source, a period of time during which the plurality of phase signals are obtained, and a result of the calculating.

Abstract: A range-finding device including a light-emitting device, an imaging unit, a calculator, and a controller. The image unit receives pulsed light reflected from an object within the space for a plurality of time periods in a time-division manner, electrically converts the pulsed light into an electrical signal, and accumulates electric charge of the electrical signal for each of the plurality of time periods. The calculator calculates a time difference between emission of the pulsed light and reception of the pulsed light reflected from the object based on the electric charge accumulated for each of the plurality of time periods and determine a distance to the object based on the time difference. The controller controls the timing of reception of the pulsed light for each of the plurality of time periods at the imaging unit according to an intensity of the pulsed light reflected from the object.

Abstract: An distance measurement apparatus includes a light source to emit irradiation light, circuitry to output, to the light source, a first current that changes in accordance of light-emission timing information defining at least turn-on timing of the light source, and a second current that does not change in accordance of the light-emission timing information, a sensor to detect reflection light reflected from an object irradiated with the irradiation light emitted from the light source. The circuitry calculates a distance to the object based on a detection amount of the reflection light detected by the sensor.

Abstract: A distance-measuring apparatus and a distance-measuring method. The distance-measuring apparatus and the distance-measuring method include emitting pulsed light, receiving and photoelectrically converting the pulsed light emitted and reflected by an object into a plurality of electrical signals, sorting the electrical signals into a plurality of phase signals, storing data including the phase signals or a value that is based on the phase signals, determining whether or not a dynamic change is present in the object, based on the data of a current frame and at least one past frame, and calculating distance to the object using the data, according to a result of determination made by the determining. When determined that the dynamic change is not present, moving average calculations are performed on the data of at least two of the current frame and a plurality of frames including the at least one past frame.

Abstract: A distance measurement device includes a projection optical system, a light-receiving system to receive light projected from projection optical system and reflected by an object; and a correction system to correct a difference in timing of light emission between the plurality of light sources. The projection optical system includes a plurality of light sources and a plurality of drive circuits to drive the plurality of light sources.

Abstract: A distance measurement device includes a projection optical system, a light-receiving system to receive light projected from projection optical system and reflected by an object; and a correction system to correct a difference in timing of light emission between the plurality of light sources. The projection optical system includes a plurality of light sources and a plurality of drive circuits to drive the plurality of light sources.

Abstract: A range finding apparatus includes a light emission unit including a light source and a light source driver, a light detection unit, and circuitry. The light source driver supplies a plurality of drive pulses having different pulse width at different time periods. The light detection unit receives the light emitted from the light emission unit and then reflected from an object. The circuitry calculates a range to the object based on a time difference between one time point when a pulse light is emitted from the light source and another time point when light reflected from the object is received by the light detection unit. One of the drive pulses set with a smaller pulse width is set with a sine wave pattern, and another one of the drive pulses set with a greater pulse width is set with a rectangular wave pattern.

Abstract: It is intended to provide an antitumor drug having an excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. There is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-TROP2 antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-(CH2)n2-C(?O)— wherein the anti-TROP2 antibody is connected to the terminal of L1, and the antitumor compound is connected to the carbonyl group of the —(CH2)n2-C(?O)— moiety with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: It is intended to provide an antitumor drug having an excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. There is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-TROP2 antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-(CH2)n2-C(?O)— wherein the anti-TROP2 antibody is connected to the terminal of L1, and the antitumor compound is connected to the carbonyl group of the —(CH2)n2-C(?O)— moiety with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: An input operation detection device to detect input operation input to an image includes a first and second imaging parts and a processor to detect input operation based on data acquired by the first and second imaging parts. The image is divided into first and second images. The optical axes of imaging optical systems of the first and second imaging parts intersect with the image at points on the same side as installation position sides of the corresponding imaging parts with respect to the center of the corresponding images.

Abstract: An distance measurement apparatus includes a light source to emit irradiation light, circuitry to output, to the light source, a first current that changes in accordance of light-emission timing information defining at least turn-on timing of the light source, and a second current that does not change in accordance of the light-emission timing information, a sensor to detect reflection light reflected from an object irradiated with the irradiation light emitted from the light source. The circuitry calculates a distance to the object based on a detection amount of the reflection light detected by the sensor.

Abstract: A distance-measuring apparatus, a mobile object, a robot, a three-dimensional measuring device, a surveillance camera, and a distance-measuring method. The distance-measuring apparatus, a mobile object includes a light source to emit light, an imaging element to receive and photoelectrically convert the light into a plurality of electrical signals, and to obtain the electrical signals upon being sorted into a plurality of phase signals, and a computing unit to calculate distance to the object based on the phase signals. In the distance-measuring apparatus, a period of time during which the imaging element obtains the phase signals is different from a light emitting period of the light source in length. The distance-measuring method includes determining whether or not aliasing is present based on a light emitting period of the light source, a period of time during which the plurality of phase signals are obtained, and a result of the calculating.

Abstract: A distance-measuring apparatus and a distance-measuring method. The distance-measuring apparatus and the distance-measuring method include emitting pulsed light, receiving and photoelectrically converting the pulsed light emitted and reflected by an object into a plurality of electrical signals, sorting the electrical signals into a plurality of phase signals, storing data including the phase signals or a value that is based on the phase signals, determining whether or not a dynamic change is present in the object, based on the data of a current frame and at least one past frame, and calculating distance to the object using the data, according to a result of determination made by the determining. When determined that the dynamic change is not present, moving average calculations are performed on the data of at least two of the current frame and a plurality of frames including the at least one past frame.

Abstract: It is intended to provide an antitumor drug having an excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. There is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-TROP2 antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-(CH2)n2-C(?O)— wherein the anti-TROP2 antibody is connected to the terminal of L1, and the antitumor compound is connected to the carbonyl group of the —(CH2)n2-C(?O)— moiety with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: It is intended to provide an antitumor drug having an excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. There is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-TROP2 antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-(CH2)n2-C(?O)— wherein the anti-TROP2 antibody is connected to the terminal of L1, and the antitumor compound is connected to the carbonyl group of the —(CH2)n2-C(?O)— moiety with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: A range finding apparatus includes a light emission unit including a light source and a light source driver, a light detection unit, and circuitry. The light source driver supplies a plurality of drive pulses having different pulse width at different time periods. The light detection unit receives the light emitted from the light emission unit and then reflected from an object. The circuitry calculates a range to the object based on a time difference between one time point when a pulse light is emitted from the light source and another time point when light reflected from the object is received by the light detection unit. One of the drive pulses set with a smaller pulse width is set with a sine wave pattern, and another one of the drive pulses set with a greater pulse width is set with a rectangular wave pattern.