Abstract: The present invention relates to a medical imaging apparatus. The apparatus comprises an ultrasound acquisition unit including an ultrasound probe for acquiring ultrasound image data of a patient. An image data interface is provided for receiving 3D medical image data of the patient and a position determining unit for determining a position of the ultrasound probe. A calibration unit determines a transfer function between the ultrasound image data and the 3D medical image data at a plurality of positions (C) of the ultrasound probe and provides a corresponding plurality of calibrated transfer functions and calibration positions. A computation unit synchronizes the ultrasound image data and the 3D medical image data on the basis of a position of the ultrasound probe and the plurality of calibrated transfer functions, said computation unit is further adapted to weight the calibrated transfer functions on the basis of a position of the ultrasound probe.

Abstract: The present disclosure describes ultrasound imaging systems and methods that may be used to image, for example, breast tissue. An ultrasound imaging system according to one embodiment may include a probe, a sensor attached to the probe and operatively associated with a position tracking system, a processor configured to receive probe position data from the position tracking system. The user interface may be configured to provide instructions for placement of the probe at a plurality of anatomical landmarks of a selected breast of the subject and receive user input to record the spatial location of the probe at each of the plurality of anatomical landmarks. The processor may be configured to determine a scan area based on the spatial location of the probe at each of the plurality of anatomical landmarks and generate a scan pattern for the selected breast. The processor may be further configured to monitor movement of the probe.

Abstract: An object of the invention is to provide titanium dioxide coloring particles capable of developing colors other than red and yellow while maintaining non-toxicity of titanium dioxide and a titanium dioxide particle mixture containing the titanium dioxide coloring particles, and to provide a method capable of producing the titanium dioxide coloring particles exhibiting the excellent properties by a simple process with a small environmental load. The invention relates to titanium dioxide coloring particles having a brookite type or rutile type crystal structure and co-doped with at least nitrogen and boron, a titanium dioxide particle mixture containing the titanium dioxide coloring particles, and a method for producing the titanium dioxide coloring particles in which a hydrothermal reaction of titanium diboride is caused in presence of an acid or urea, and then a nitriding treatment is performed in an ammonia gas atmosphere or by mixing with urea or carbon nitride.

Abstract: This application provides a data management system, method, terminal, and medium based on hybrid storage. The data management system includes: a first file system mount module, to mount at least one user-mode file system; a second file system mount module, to mount at least two independent back-end file systems based on the user-mode file system for storing hot data and cold data respectively; a data label module, to label the hot or cold attribute of the data in a user data request; a file system selection module, to store the data in the corresponding back-end file system and/or take the data out from the corresponding back-end file system according to the hot or cold attribute of the data.

Abstract: A fusion imaging system co-registers and fuses real time ultrasound images with reference images such as those produced by MRI or CT imaging. In an illustrated implementation, previously acquired CT or MRI or ultrasound images are loaded into the system. An ultrasound system is operated in conjunction with a tracking system so that the ultrasound probe and images can be spatially tracked. A computerized image processor registers the probe position with a reference image of the anatomy being scanned by the probe and determines whether the probe appears to be inside the skin line of the subject. If that is the case it is due to probe compression of the subject, and the reference image is modified to locate the skin line in the reference image in front of the ultrasound probe. The modified reference images can then be readily co-registered and fused with the ultrasound images produced by the probe.

Abstract: Disclosed herein is a process for producing a recombinant Candida cell, which involves genetically engineering a parent Candida cell using a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas)(CRISPR/Cas) system. A recombinant Candida cell obtained using the process and a method for producing D-lactic acid from a biomass using the recombinant Candida cell are also disclosed.

Abstract: A method for neural network computation using adaptive data representation, adapted for a processor to perform multiply-and-accumulate operations on a memory having a crossbar architecture, is provided. The memory comprises multiple input and output lines crossing each other, multiple cells respectively disposed at intersections of the input and output lines, and multiple sense amplifiers respectively connected to the output lines. In the method, an input cycle of kth bits respectively in an input data is adaptively divided into multiple sub-cycles, wherein a number of the divided sub-cycles is determined according to a value of k. The kth bits of the input data are inputted to the input lines with the sub-cycles and computation results of the output lines are sensed by the sense amplifiers. The computation results sensed in each sub-cycle are combined to obtain the output data corresponding to the kth bits of the input data.

Abstract: A method for processing a cotton-containing textile waste includes: separating cotton fibers from a batch of the textile waste; pretreating the cotton fibers by soaking in a hydroxide-ion-containing solution to obtain a mixture including pretreated carbon fibers; removing a liquid portion from the mixture to obtain the pretreated carbon fibers; subjecting the pretreated carbon fibers to enzymatic hydrolysis to form a sugary juice containing glucose; and e) adding the liquid portion as part of the hydroxide-ion-containing solution for pretreating the cotton fibers separated from a next batch of the textile waste.

Abstract: A fusion imaging system co-registers and fuses real time ultrasound images with reference images such as those produced by MRI or CT imaging. In an illustrated implementation, previously acquired CT or MRI or ultrasound images are loaded into the system. An ultrasound system is operated in conjunction with a tracking system so that the ultrasound probe and images can be spatially tracked. A computerized image processor registers the probe position with a reference image of the anatomy being scanned by the probe and determines whether the probe appears to be inside the skin line of the subject. If that is the case it is due to probe compression of the subject, and the reference image is modified to locate the skin line in the reference image in front of the ultrasound probe. The modified reference images can then be readily co-registered and fused with the ultrasound images produced by the probe.

Abstract: The present disclosure describes ultrasound imaging systems and methods, which may enable the automatic identification of an image plane in a pre-operative volume corresponding to a real-time image of a moving region of interest. An example method includes receiving real-time ultrasound image data from a probe associated with a position-tracking sensor, generating real-time images based on the real-time ultrasound data and deriving a motion model from the real-time ultrasound image data. The method may further include automatically identifying an image plane in a pre-operative data set to correspond to the real-time ultrasound image by correcting for motion-induced misalignment between the real-time data and the pre-operative data.

Abstract: A method for neural network computation using adaptive data representation, adapted for a processor to perform multiply-and-accumulate operations on a memory having a crossbar architecture, is provided. The memory comprises multiple input and output lines crossing each other, multiple cells respectively disposed at intersections of the input and output lines, and multiple sense amplifiers respectively connected to the output lines. In the method, an input cycle of kth bits respectively in an input data is adaptively divided into multiple sub-cycles, wherein a number of the divided sub-cycles is determined according to a value of k. The kth bits of the input data are inputted to the input lines with the sub-cycles and computation results of the output lines are sensed by the sense amplifiers. The computation results sensed in each sub-cycle are combined to obtain the output data corresponding to the kth bits of the input data.

Abstract: The present disclosure describes ultrasound imaging systems and methods that may be used to image, for example, breast tissue. An ultrasound imaging system according to one embodiment may include a probe, a sensor attached to the probe and operatively associated with a position tracking system, a processor configured to receive probe position data from the position tracking system. The user interface may be configured to provide instructions for placement of the probe at a plurality of anatomical landmarks of a selected breast of the subject and receive user input to record the spatial location of the probe at each of the plurality of anatomical landmarks. The processor may be configured to determine a scan area based on the spatial location of the probe at each of the plurality of anatomical landmarks and generate a scan pattern for the selected breast. The processor may be further configured to monitor movement of the probe.

Abstract: A fusion imaging system co-registers and fuses real time ultrasound images with reference images such as those produced by MRI or CT imaging. In an illustrated implementation, previously acquired CT or MRI or ultrasound images are loaded into the system. An ultrasound system is operated in conjunction with a tracking system so that the ultrasound probe and images can be spatially tracked. A computerized image processor registers the probe position with a reference image of the anatomy being scanned by the probe and determines whether the probe appears to be inside the skin line of the subject. If that is the case it is due to probe compression of the subject, and the reference image is modified to locate the skin line in the reference image in front of the ultrasound probe. The modified reference images can then be readily co-registered and fused with the ultrasound images produced by the probe.

Abstract: A method and an apparatus for neural network computation using adaptive data representation, adapted for a processor to perform multiply-and-accumulate operations on a memory having a crossbar architecture, are provided. The memory comprises multiple input and output lines crossing each other, multiple cells respectively disposed at intersections of the input and output lines, and multiple sense amplifiers respectively connected to the output lines. In the method, an input cycle of kth bits respectively in an input data is adaptively divided into multiple sub-cycles, wherein a number of the divided sub-cycles is determined according to a value of k. The kth bits of the input data are inputted to the input lines with the sub-cycles and computation results of the output lines are sensed by the sense amplifiers. The computation results sensed in each sub-cycle are combined to obtain the output data corresponding to the kth bits of the input data.

Abstract: The present disclosure describes ultrasound imaging systems and methods that may be used to image, for example, breast tissue. An ultrasound imaging system according to one embodiment may include a probe, a sensor attached to the probe and operatively associated with a position tracking system, a processor configured to receive probe position data from the position tracking system. The user interface may be configured to provide instructions for placement of the probe at a plurality of anatomical landmarks of a selected breast of the subject and receive user input to record the spatial location of the probe at each of the plurality of anatomical landmarks. The processor may be configured to determine a scan area based on the spatial location of the probe at each of the plurality of anatomical landmarks and generate a scan pattern for the selected breast. The processor may be further configured to monitor movement of the probe.

Abstract: Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.

Abstract: Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.

Abstract: An operation method of an artificial neural network is provided. The operation method includes: dividing input information into a plurality of sub-input information, and expanding kernel information to generate expanded kernel information; performing a Fast Fourier Transform (FFT) on the sub-input information and the expanded kernel information to respectively generate a plurality of frequency domain sub-input information and frequency domain expanded kernel information; respectively performing a multiplying operation on the frequency domain expanded kernel information and the frequency domain sub-input information to respectively generate a plurality of sub-feature maps; and performing an inverse FFT on the sub-feature maps to provide a plurality of converted sub-feature maps for executing a feature extraction operation of the artificial neural network.

Abstract: This application provides a data management system, method, terminal, and medium based on hybrid storage. The data management system includes: a first file system mount module, to mount at least one user-mode file system; a second file system mount module, to mount at least two independent back-end file systems based on the user-mode file system for storing hot data and cold data respectively; a data label module, to label the hot or cold attribute of the data in a user data request; a file system selection module, to store the data in the corresponding back-end file system and/or take the data out from the corresponding back-end file system according to the hot or cold attribute of the data.

Abstract: The present disclosure describes ultrasound imaging systems and methods, which may enable the automatic identification of an image plane in a pre-operative volume corresponding to a real-time image of a moving region of interest. An example method includes receiving real-time ultrasound image data from a probe associated with a position-tracking sensor, generating real-time images based on the real-time ultrasound data and deriving a motion model from the real-time ultrasound image data. The method may further include automatically identifying an image plane in a pre-operative data set to correspond to the real-time ultrasound image by correcting for motion-induced misalignment between the real-time data and the pre-operative data.