Abstract: Provided are an antibody and a preparation method therefor. The antibody is, such as a humanized anti-human CD47 monoclonal antibody or fragment thereof, and a bispecific antibody targeting PD-L1 and CD47 or an antigen-binding fragment thereof. The bispecific antibody comprises two heavy chains and two light chains, variable regions of the two heavy chains are heterologous, and variable regions of the two light chains have similar sequences. The provided bispecific antibody has the light chains having the similar sequences, thus solving the technical problem of light and heavy chain mismatch during an assembly process of bispecific antibodies.

Abstract: An array substrate includes a plurality of TFT switches arranged in an array and a scan driver circuit. In each row of TFT switches, a plurality of TFT switches form a first group of switches, and the rest of the TFT switches form a second group of switches. The scan driver circuit outputs first and second scan signals for each row of the TFT switches. The first group of switches receives the first scan signal, and the second group of switches receives the second scan signal. When a static image is displayed, the first scan signal or the second scan signal is an off signal to turn off the first or second group of switches.

Abstract: A data driving circuit, a display module, and a display device are provided. The data driving circuit at least includes a selecting unit and a signal conversion unit. The selecting unit is configured to directly output an image signal received to the signal conversion unit, or invert the image signal and then transmit the image signal inverted to the signal conversion unit. The control signal represents a display mode of a pixel unit that receives the image signal and perform image display according to the image signal. The signal conversion unit is configured to convert the image signal into a grayscale voltage in an analog form. The grayscale voltage is transmitted to the pixel unit to perform image display.

Abstract: In view of the technical problem that TGF-? RH and a fusion protein thereof are prone to degradation and breakage during the process of recombinant expression, provided are a TGF-? RII mutant and a fusion protein thereof. Compared with the extracellular region of the wild-type TGF-? RII of SEQ ID NO: 6, the TGF-? RII mutant has a mutation selected from Gln at position 6, Asp at position 12 and Gly at position 20. The TGF-? RII mutant is capable of binding to TGF-?. Compared to wild-type TGF-? RII, the TGF-? RII mutant has less breakage and/or degradation during recombination expression. It is convenient for large-scale production of antibodies/the TGF-? RII bifunctional protein with a more stable quality.

Abstract: The present invention provides a system for on-line detecting the package airtightness of cigarette packet, which comprises a first conveyor belt; a plurality of detection box bases arranged on the first conveyor belt at preset intervals, wherein the cigarette packets are sequentially conveyed onto each detection box base; a second conveyor belt arranged above the first conveyor belt, and the central plane of the second conveyor belt being in coincide with the central plane of the first conveyor belt; a plurality of detection box covers arranged on the second conveyor belt at preset intervals, wherein each detection box cover is provided with a slit on one side face, and the detection box cover positioned on the lower end face of the second conveyor belt is cooperated with the detection box base directly below the second conveyor belt during the detection; and a detection probe aligned with the slit during the detection so as to detect the package airtightness of the cigarette packet positioned within the det

Abstract: An inclination angle control instrument for screw anchor installation is provided, relates to the technical field of geotechnical engineering. The inclination angle control instrument for screw anchor installation includes a triangular base and side plates hinged to three sides of the triangular base respectively. A platform assembly for placing a screw anchor clamp is arranged above the triangular base, transmission assemblies are arranged on the platform assembly, each of the transmission assemblies drives a corresponding one of the side plates to rotate on the triangular base. The inclination angle control instrument for screw anchor installation can be spread and retracted more conveniently, thereby improving the working efficiency of the inclination angle control instrument for screw anchor installation.

Abstract: A semiconductor package is disclosed. In one example, the semiconductor package comprises a package body and a second die pad at least partially encapsulated in the package body. A first semiconductor die is at least partially encapsulated in the package body and arranged on the first die pad. A further device at least partially encapsulated in the package body and arranged on the second die pad. At least one first lead is connected with the first contact pad of the first semiconductor die. At least one second lead is connected with the second contact pad of the further device. An electrical conductor is connected between the at least one first lead and the at least one second lead, the electrical conductor being completely encapsulated in the package body.

Abstract: A semiconductor device includes a carrier, a first external contact, a second external contact, and a semiconductor die. The semiconductor die has a first main face, a second main face opposite to the first main face, a first contact pad disposed on the first main face, a second contact pad disposed on the second main face, a third contact pad disposed on the second main face, and a vertical transistor. The semiconductor die is disposed with the first main face on the carrier. A clip connects the second contact pad to the second external contact. A first bond wire is connected between the third contact pad and the first external contact. The first bond wire is disposed at least partially under the clip.

Abstract: Systems and methods are provided for displaying augmented reality image content perceived as being overlaid on background image content viewed through a light-transmissive viewing surface. Image processing circuitry may receive input augmented reality image data corresponding with a pixel position on the display panel, determine a perceived background brightness metric indicative of background brightness level at the pixel position based at least in part on captured background image data and an ambient lighting metric, determine a target tone mapping based at least in part on the perceived background brightness metric, and determine display augmented reality image data to be used by a display panel to display the augmented reality image content least in part by applying the target tone mapping to the input augmented reality image data.

Abstract: The invention provides a method for monitoring health state of blade root fastener, comprising the following steps: obtaining a sequence of acceleration signals representing the lateral vibration of the nacelle and a sequence of rotational speed signals representing the rotational speed of the rotor; analyzing the sequence of acceleration signals and the sequence of rotational speed signals to determine the amplitude of the nacelle at 2-time-frequncy of the rotational speed of the rotor; and determining the health state of the blade root fastener based on the amplitude. The invention also provides a system for monitoring the health state of the blade root fastener. Through the present invention, the health state of the blade root fastener can be determined with low cost and high precision, thereby improving the operation efficiency and operation safety of the wind turbine.

Abstract: A semiconductor package is disclosed. In one example, the semiconductor package includes a package body. A first diepad is at least partially uncovered by the package body at the first main surface. A second diepad is at least partially uncovered by the package body at the first main surface. A first semiconductor chip is arranged on the first diepad. A second semiconductor chip is arranged on the second diepad. The semiconductor package further includes at least one lead protruding out of the package body at the side surface. A first groove is formed in the first main surface, wherein the first groove is arranged between the first diepad and the second diepad, and a second groove is formed in the first main surface, wherein the second groove is arranged between the at least one lead and at least one of the first diepad and the second diepad.

Abstract: In one embodiment, a computing system may determine, determine an estimated distance of an eye of a user to a display plane of a display. The system may access correction maps corresponding to a number of reference distances to the display plane of the display. The system may select a first reference distance and a second reference distance based on the estimated distance. The system may generate a custom correction map for the user based on an interpolation of a first correction map corresponding to the first reference distance and a second correction map corresponding to the second reference distance. The system may adjust an image to be displayed on the display using the custom correction map. The custom correction map may correct non-uniformity of the display as viewed from the eye of the user. The system may display the image adjusted using the custom correction map on the display.

Abstract: A display panel and a drive circuit of the same are provided. The drive circuit includes multiple drive circuit rows. Each of the drive circuit rows includes multiple pixel drive circuits and a signal processing circuit. According to the drive circuit, a signal processing circuit can obtain a drive signal by processing a scan signal and a light-emitting control signal of a drive circuit row to which the signal processing circuit belongs, and can output the drive signal to each pixel drive circuit in the drive circuit row to which the signal processing circuit belongs; a pixel drive circuit can form a capacitor-reset loop by multiplexing a first switch tube in a light-emitting element reset loop of the pixel drive circuit, a second switch tube in a data-writing loop of the pixel drive circuit, and a third switch tube in a light-emitting loop of the pixel drive circuit.

Abstract: Provided are a single variable domain antibody targeting a human programmed death ligand 1 (PD-L1) and a derivative thereof. A single variable domain antibody 2-2F2 specific for human PD-L1 is identified and obtained by extracting PBMCs from a camel immunized with human PD-L1, constructing a phage surface displayed VHH antibody library, and screening said VHH antibody library. On said basis, a chimeric antibody chF2 and a humanized modified antibody hzF2 variant are prepared. The hzF2 variant possesses affinity comparable or even superior to that of the original single variable domain antibody 2-2F2, can block the binding of PD-1 to PD-L1 in vitro, and can inhibit tumor growth in an in vivo experiment on tumor-bearing mice.

Abstract: A display panel and a drive circuit of the same are provided. The drive circuit includes multiple drive circuit rows. Each of the drive circuit rows includes multiple pixel drive circuits and a signal processing circuit. According to the drive circuit, a signal processing circuit can obtain a drive signal by processing a scan signal and a light-emitting control signal of a drive circuit row to which the signal processing circuit belongs, and can output the drive signal to each pixel drive circuit in the drive circuit row to which the signal processing circuit belongs; a pixel drive circuit can form a capacitor-reset loop by multiplexing a first switch tube in a light-emitting element reset loop of the pixel drive circuit, a second switch tube in a data-writing loop of the pixel drive circuit, and a third switch tube in a light-emitting loop of the pixel drive circuit.

Abstract: In accordance with some implementations, a method is performed at an electronic device with one or more processors, a non-transitory memory, and a see-through display. The method includes determining a plurality of light superposition characteristic values associated with ambient light from a physical environment. The plurality of light superposition characteristic values quantifies the ambient light. The method includes modifying image data in order to generate modified image data, based on a function of the plurality of light superposition characteristic values and a reference perceptual gamut. The method includes transforming the modified image data into display data based on a function of a portion of the plurality of light superposition characteristic values and a reference physical gamut that is associated with the see-through display. The method includes displaying the display data on the see-through display.

Abstract: The invention provides a carbon-heated cigarette which comprises a carbon rod section, a tobacco section, a smoke extraction section and a filter section which are sequentially arranged from an upstream to a downstream. The carbon-heated cigarette can also comprise a composite paper and an outer wrapper wrapped around the outsides of the composite paper, the tobacco section, the smoke extraction section and the filter section. The composite paper is wrapped around a part of the carbon rod section and a part of or the entire tobacco section. The smoke extraction section has a cavity passing therethrough in an axial direction, and has a side wall having at least one side wall through-hole that communicates with the cavity. A wrapper through-hole is formed on the outer wrapper at a position corresponding to the side wall through-hole so as to allow the external air enter the smoke extraction section.

Abstract: In one embodiment, a computing system may determine, determine an estimated distance of an eye of a user to a display plane of a display. The system may access correction maps corresponding to a number of reference distances to the display plane of the display. The system may select a first reference distance and a second reference distance based on the estimated distance. The system may generate a custom correction map for the user based on an interpolation of a first correction map corresponding to the first reference distance and a second correction map corresponding to the second reference distance. The system may adjust an image to be displayed on the display using the custom correction map. The custom correction map may correct non-uniformity of the display as viewed from the eye of the user. The system may display the image adjusted using the custom correction map on the display.

Abstract: A retinomorphic array is used to convert visual information into electrical signals, and the neural network performs information processing on the input electrical signals to obtain the result of visual cognition; the perception and synchronous preprocessing of visual information is achieved through the retinomorphic array, avoiding the transmission of a large number of redundant visual information from the photoreceptor end to the image information processor, saving bandwidth resources, and improving the efficiency of visual information processing; the use of the crossbar array allows the configuration of a neural network with a more complex structure and more diverse functions, and the higher-level processing of visual information by the neural network realizes a novel neuromorphic vision system integrated therein with image recognition, dynamic tracking, and trajectory prediction.

Abstract: A semiconductor package is disclosed. In one example, the semiconductor package includes a chip carrier, a semiconductor chip attached to the chip carrier, an encapsulation body encapsulating the semiconductor chip, and a mounting hole configured to receive a screw for screw mounting a heatsink onto a first side of the semiconductor package. A second side of the semiconductor package opposite the first side is configured to be surface mounted to an application board.