Patents by Inventor Sidney M. Hecht

Sidney M. Hecht has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4590264
    Abstract: This invention provides novel lipoglycosides having the structural formula: ##STR1## wherein R.sub.1 and R.sub.2 are different and are selected from the group consisting of hydrogen and ##STR2## The lipoglycosides have antitumor properties.
    Type: Grant
    Filed: August 11, 1983
    Date of Patent: May 20, 1986
    Assignee: Wofor AG
    Inventors: Sidney M. Hecht, David G. Lynn, Kalakota S. Reddy
  • Patent number: 4454124
    Abstract: This invention provides an extract from the plant Cerastium viscusum L. (Coryophyllaceae) Mississippi and a method of obtaining same. The extract is obtained by subjecting the plant to a series of extraction steps with a plurality of solvents having different polarities. In each extraction step, the solvent used has a polarity higher than that used in the preceding extraction step. All extraction steps are conducted at room temperature. The extracts have been found to possess biological activity.
    Type: Grant
    Filed: February 18, 1983
    Date of Patent: June 12, 1984
    Assignee: WOFOR AG
    Inventor: Sidney M. Hecht
  • Patent number: 4451459
    Abstract: This invention provides an extract from the plant Myrcia fallax (Myrtaceae) Peru and a method of obtaining same. The extract is obtained by subjecting the plant to a series of extraction steps with a plurality of solvents having different polarities. In each extraction step, the solvent used has a polarity higher than that used in the preceding extraction step. All extraction steps are conducted at room temperature. The extracts have been found to possess biological activity.
    Type: Grant
    Filed: July 23, 1982
    Date of Patent: May 29, 1984
    Assignee: Wofor AG
    Inventor: Sidney M. Hecht
  • Patent number: 4405613
    Abstract: This invention provides an extract from the plant Maytenus nemerosa (Eckl & Zeyh) Morais (Celastroceae) South Africa and a method of obtaining same. The extract is obtained by subjecting the plant to a series of extraction steps with a plurality of solvents having different polarities. In each extraction step, the solvent used has a polarity higher than that used in the preceding extraction step. All extraction steps are conducted at room temperature. The extracts have been found to possess biological activity.
    Type: Grant
    Filed: July 23, 1982
    Date of Patent: September 20, 1983
    Inventor: Sidney M. Hecht
  • Patent number: 4352797
    Abstract: This invention provides an extract from the plant Myristica castaneifolia (Myristacaceae) Fiji and a method of obtaining same. The extract is obtained by subjecting the plant to a series of extraction steps with a plurality of solvents having different polarities. In each extraction step, the solvent used has a polarity higher than that used in the preceding extraction step. All extraction steps are conducted at room temperature. The extracts have been found to possess biological activity.
    Type: Grant
    Filed: July 2, 1981
    Date of Patent: October 5, 1982
    Assignee: Wofor AG
    Inventor: Sidney M. Hecht
  • Patent number: 4282361
    Abstract: An improved synthesis is disclosed for 7-alkylamino-3-methylpyrazolo[4,3-d]pyrimidines, which are known to be potent cytokinin antagonists.
    Type: Grant
    Filed: March 16, 1978
    Date of Patent: August 4, 1981
    Assignee: Massachusetts Institute of Technology
    Inventors: Sidney M. Hecht, Ulrich Jordis
  • Patent number: 3988338
    Abstract: A series of compounds having anticytokinin activity comprising 7-amino-substituted-2-alkylthio or alkoxypyrrolo [2,3-d] pyrimidine derivatives in which the alkyl group has from 1 to 10 and preferably 4 to 7 carbon atoms and which may be substituted with halogen or hydroxyl groups.
    Type: Grant
    Filed: April 24, 1974
    Date of Patent: October 26, 1976
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Folke Skoog, Ruth Y. Schmitz, Sidney M. Hecht, Robert B. Frye
  • Patent number: 3963698
    Abstract: Alkylation processes wherein diazoalkane alkylation reagents are generated in situ and utilized to alkylate substrates are disclosed. These processes utilize the relatively slow base-catalyzed decomposition of an N-alkyl, N-nitrosourea to produce a corresponding diazoalkane alkylation reagent, followed by the much faster reaction between the alkylation reagent and the substrate to be alkylated. Generically, suitable ureas can be represented by the structural formula, ##EQU1## wherein R represents the alkyl moiety to be added to the substrate; R can be alkyl, cycloalkyl, heteroalkyl, aralkyl or heterocyclic.This process is useful in producing alkylated products without the concomitant disadvantage of building up significant amounts of diazoalkane alkylation reagents during the course of the reaction, many of which have deleterious properties.
    Type: Grant
    Filed: January 17, 1974
    Date of Patent: June 15, 1976
    Assignee: Massachusetts Institute of Technology
    Inventors: Sidney M. Hecht, John W. Kozarich