Patents by Inventor Sidney Wallace
Sidney Wallace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20030147807Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: December 5, 2002Publication date: August 7, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030134793Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or -lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: October 28, 2002Publication date: July 17, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030130170Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: November 18, 2002Publication date: July 10, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030130341Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: November 18, 2002Publication date: July 10, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030130178Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: November 18, 2002Publication date: July 10, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030124055Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: December 5, 2002Publication date: July 3, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030114397Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: September 12, 2002Publication date: June 19, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030114363Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: September 12, 2002Publication date: June 19, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030113335Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: September 12, 2002Publication date: June 19, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030114518Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: September 12, 2002Publication date: June 19, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Patent number: 6551340Abstract: A coil-type vasoocclusion device (10) for establishing an embolus or vascular occlusion in a human or veterinary patient is adapted for introduction into the patient via a catheter (32). The device (10) first includes a coil (12) having proximal and distal coil ends (16,18) and a coil lumen (20). The device (10) also includes a core (22) disposed in at least part of the coil lumen (20), the core having proximal and distal core ends (24,26). Only one core end (24 or 26) is directly affixed to a respective end (16 or 18) of the coil (12); the other core end (26 or 24) is not directly connected to either end (16 or 18) of the coil (12). The core (22) is preferably nitinol in a superelastic state, being in other than its stress induced, martensitic condition. The device (10) can include a thrombogenic material (38) connected to or carried by the coil (12). The coil (12) is preferably adapted to achieve a suitable secondary shape (60) when deployed from the catheter (32).Type: GrantFiled: October 6, 1999Date of Patent: April 22, 2003Assignee: Board of Regents The University of Texas SystemInventors: András Kónya, Sidney Wallace, Kenneth Carroll Wright
-
Publication number: 20030073615Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: May 17, 2002Publication date: April 17, 2003Applicant: Cell Therapeutics, Inc.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Publication number: 20030073617Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: ApplicationFiled: October 28, 2002Publication date: April 17, 2003Applicant: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Patent number: 6530949Abstract: A wire frame stent and stent delivery system for inserting the stent into the body.Type: GrantFiled: July 10, 2001Date of Patent: March 11, 2003Assignee: Board of Regents, The University of Texas SystemInventors: Andres Konya, Sidney Wallace, Kenneth C. Wright
-
Patent number: 6515017Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: GrantFiled: May 24, 2002Date of Patent: February 4, 2003Assignee: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David Yang
-
Publication number: 20030003048Abstract: Conjugate molecules comprising a ligand bonded to a polymer are disclosed. One such conjugate molecule comprises a ligand bonded to a polymer, a chelating agent bonded to the polymer, and a radioisotope chelated to the chelating agent. The conjugate molecules may be useful in detecting and/or treating tumors or biological receptors. These conjugate molecules may be synthesized without the necessity of preactivation of the ligand using an SCN-polymer-chelating agent precursor. Conjugate molecules incorporating an annexin V ligand are particularly useful for visualizing apoptotic cells. Conjugate molecules incorporating a C225 ligand are particularly useful for targeting tumors expressing EGFR.Type: ApplicationFiled: April 19, 2002Publication date: January 2, 2003Inventors: Chun Li, Xiaoxia Wen, Qing-Ping Wu, Sidney Wallace, Lee M. Ellis
-
Publication number: 20020197261Abstract: Conjugate molecules comprising a ligand or targeting moiety bonded to a polymer spacer, a polymer carrier bonded to the polymer spacer, and a therapeutic agent bound to the polymer carrier (with or without a linker) are disclosed. The conjugate molecules are useful for the selective delivery of therapeutic agents to tumors or other tissues expressing biological receptors.Type: ApplicationFiled: April 19, 2002Publication date: December 26, 2002Inventors: Chun Li, Javier O. Vega, Shi Ke, Sidney Wallace
-
Publication number: 20020156499Abstract: An occlusion method and apparatus. The occluder includes a elastically deformable members and a jacket. The elastically deformable members are secured in spaced relation and extend in arcuate conformation therebetween. The jacket covers at least a portion of the elastically deformable members. The elastically deformable members are configured to become compressed upon application of a force and to recover the arcuate conformation upon removal of the force to occlude a site.Type: ApplicationFiled: April 9, 2002Publication date: October 24, 2002Inventors: Andras Konya, Sidney Wallace, Kenneth C. Wright
-
Patent number: 6441025Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.Type: GrantFiled: March 30, 1998Date of Patent: August 27, 2002Assignee: PG-TXL Company, L.P.Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
-
Patent number: 6368338Abstract: An occlusion method and apparatus. The occluder includes a elastically deformable members and a jacket. The elastically deformable members are secured in spaced relation and extend in arcuate conformation therebetween. The jacket covers at least a portion of the elastically deformable members. The elastically deformable members are configured to become compressed upon application of a force and to recover the arcuate conformation upon removal of the force to occlude a site.Type: GrantFiled: March 5, 1999Date of Patent: April 9, 2002Assignee: Board of Regents, The University of TexasInventors: András Kónya, Sidney Wallace, Kenneth C. Wright