Abstract: Provision of a chimeric antigen receptor (CAR) comprising a disialoganglioside (GD2)-binding domain which comprises a) a heavy chain variable region (VH) having complementarity determining regions (CDRs) with the following sequences: b) a light chain variable region (VL) having CDRs with the following sequences: T cells expressing such a CAR are useful in the treatment of some cancers.

Abstract: An intake manifold with a single and dual plane adapter is provided. The intake manifold includes a plenum chamber. The plenum chamber may include a first side, a second side, a bottom portion, and a top portion. The adapter may include a guide rail attached to the plenum chamber and forming a channel in between. A divider is formed to fit within the channel. An actuator is operatively connected to extend and retract the divider within the channel. Therefore, the divider includes an extended position forming a dual chamber within the plenum chamber, and a retracted position forming a single chamber within the plenum chamber.

Abstract: An intake manifold with a single and dual plane adapter is provided. The intake manifold includes a plenum chamber. The plenum chamber may include a first side, a second side, a bottom portion, and a top portion. The adapter may include a guide rail attached to the plenum chamber and forming a channel in between. A divider is formed to fit within the channel. An actuator is operatively connected to extend and retract the divider within the channel. Therefore, the divider includes an extended position forming a dual chamber within the plenum chamber, and a retracted position forming a single chamber within the plenum chamber.

Abstract: The system and method provide an efficient and effective way to provision views of up to date ongoing activities associated with the works of a client (e.g., global registration of rights relating to licensing of multimedia material) by territory and content. The system provides the client a way to configure a selection précis of up to date activities and extract from a full complement of data (e.g., royalty administration and rights management life cycle metrics) received from global partners responsible for collecting work rights information. The system reformats the data received from partners into a unified format, applies compression rules to obtain an optimized summary of the data, and filters the summarized data according to the predetermined client customized preferences.

Abstract: An electrical assembly is disclosed in which two flexible printed circuits are electrically joined. This allows greater lengths of flexible printed circuits to be provided, for example for gas turbine engine harnesses. Each flexible printed circuit has a terminating region having electrically conductive through holes that are connected to respective electrical tracks of the flexible printed circuit. The terminating regions are adjacent each other in the electrical assembly, and an electrically conductive pin is passed through the aligned through holes, then permanently bonded in position, for example by welding. This results in a robust, reliable connection of two flexible printed circuits.

Abstract: A flood barrier unit having a base and at least one side wall is provided. The walls of the unit are tapered such that it is capable of being stacked vertically with other such units when not in use. The unit preferably includes at least one connection slot on each wall, wherein each connection slot is adapted to sealingly accept a connection piece. A plurality of such units may be connected together to form a watertight flood barrier, where adjacent units are adapted to be connected together in a watertight manner using one connection piece. Additional connection pieces suitable for sealingly engaging a vertical structure such as the wall of a building are also provided.

Abstract: Disclosed are methods and systems adapted to aid in a handling of sample containers (e.g., sample containers) in a processing or testing system. The method includes a sequence of motions of gripper fingers and a seater to accomplish a pick and place operation of a sample container where the sample container includes a sticky surface. A sample container positioning system is disclosed, as are other aspects.

Abstract: Targeted binding agents, such antibodies directed to the antigen ?V?6 and uses of such agents are described. In particular, fully human monoclonal antibodies directed to the antigen ?V?6 are disclosed. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3 are disclosed. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also disclosed.

Abstract: In some embodiments, a barbed tape can be formed from a planar strip of flexible material and include a plurality of barbs disposed therealong, the barbs being sufficiently resilient so as to impede, by entanglement with or otherwise, the passage of an object therepast. Apparatus for deployment of barbed tape is also described.

Abstract: There is provided a computer based system for arranging exchanges between individuals of a first group wishing to exchange a first type of items for a second type of items, and individuals of a second group wishing to exchange the second type of items for the first type of items. The system comprises a computer server with an offer interface for receiving offers from individuals of the first and second groups to exchange items at first exchange rates and second exchange rates, a display interface for outputting the offers for display, a request interface for receiving requests from the individuals of the first and second groups to make exchanges at the first exchange rates and second exchange rates, and a processor for confirming exchanges based on the requests and updating the offers that are sent for display based on the items remaining after each exchange.

Abstract: Targeted binding agents, such antibodies directed to the antigen ?V?6 and uses of such agents are described. In particular, fully human monoclonal antibodies directed to the antigen ?V?6 are disclosed. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3 are disclosed. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also disclosed.

Abstract: Technology for providing reporting options specific for a market or a common user attribute is disclosed herein. A computer server of a social networking system determines multiple community standards for a group of users of a social networking system, wherein the group of users have a common user attribute such as a common market. The computer server receives a request for reporting a content object in the social networking system from a user among the group of users. The computer server determines multiple reporting options based on the community standards, and transmits the reporting options to the user in response to the request.

Abstract: A decision support tool which takes a high-level view of supply and demand in the realm of labor resources and produces globally-optimal recommendations for assignment of practitioners to open seats. These assignments preferably optimize a utility function composed of different business metrics and can be customizable for different organizations and priorities.

Abstract: A social networking service initiates a custom resolution process when a receiving user indicates objection to a message posted by a posting user. In embodiments, the networking service provides interfaces to the receiving user to obtain information about the user's intended goal, and to elicit information from the user about the context of the user's objection. The networking service analyzes the received information to determine an emotional context associated with the objection. Based on the emotional context and also based on additional social context information associated with the two users, the networking service presents customized resolution options to the receiving user.

Abstract: A multi-configuration interface device for coupling different types of GPUs (graphics processor units) to a PCB (printed circuit board). The interface device comprises a GPU interface for a connection to the GPU and a PCB interface for a connection to the PCB. The GPU interface is implemented using a customizable attachment footprint for effectuating a connection to differing GPU types while maintaining the PCB interface for the connection to the PCB. The ball array for different GPUs can be configured to respectively support them. The interface device maintains a consistent PCB interface. Thus, as GPU characteristics change and evolve, or as different GPU versions are implemented, a consistent connection can be maintained for the PCB.

Abstract: A flood barrier comprises hollow self-filling units (10, 12, 14, 16) placed end-to-end and connected at their ends by downwardly tapered bilobal (46) keys inserted into sockets (26, 28) at the ends of the units, wherein the keys incorporate concrete or other ballast for negative buoyancy.