Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed arc uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: A central text repository may maintain, track, update, and modify text centrally that may then be distributed to applications to be used at runtime. The central text repository allows anyone involved in the software design processor lifecycle to edit, update, and/or correct text strings that are used in various applications. This allows updates to be rapidly pushed out to runtime applications without requiring the codes bases of those applications to be accessed at all. Instead, a change may be made centrally, and new resource bundles of text strings may be made available for runtime downloading usage by these applications. This effectively separates the storage and maintenance of text strings from the underlying applications. Hierarchies and modifiers may be used to override and inherit different text usages, languages, and so forth.

Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: Polypeptides comprising a C3b binding region and a C3d inactivating region are disclosed, as well as nucleic acids and vectors encoding such polypeptides. Also disclosed are cells and compositions comprising such polypeptides, and uses and methods using the same.

Abstract: Agents for reducing the gene and/or protein expression of FH family proteins are disclosed. Also disclosed are articles encoding the agents and methods of using the agents, including in therapeutic and prophylactic methods.

Abstract: Methods for detecting and determining the level of complement proteins are disclosed, in particular using mass spectrometry. Also disclosed are methods of identifying subjects having or at risk of developing a complement-related disorder, and methods of treating the same.

Abstract: Methods of identifying subjects having complement-related disorders, or at risk of such disorders, are disclosed. Also disclosed are methods for selecting subjects for treatment with complement-targeted therapies, and methods of treatment of subjects with such therapies.

Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: Methods for determining whether a subject is at risk of developing a complement-related disorder are disclosed. Also disclosed are complement-targeted therapeutics for treating a complement-related disorder, in particular agents that decrease the level of FHR-4.

Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: Aspects of the present disclosure relate to enhancing virtual reality safety. A virtual reality (VR) boundary associated with a VR system can be determined, the VR boundary dictating a safe play area for a VR user using the VR system. A location of a first device can be determined. A determination can be made that the location of the first device is within the VR boundary. In response to a determination that the first device is within the VR boundary, the VR user can be alerted that the first device entered the VR boundary.

Abstract: Systems, apparatuses, and methods for visualizing, navigating within, and interacting with data, typically organizational related data. In one embodiment, the invention may be implemented in conjunction with a business data processing system or platform. Such a system or platform may be a multi-tenant business data processing system that provides data storage and data processing capabilities for users. The data stored and/or processed may include one or more of ERP (Enterprise Resource Planning), CRM (Customer Relationship Management), HR/HCM (Human Resources/Human Capital Management), or financial business-related data.

Abstract: A system and methods for generating an interaction-weighted visualization of an organization or group, with the relationships between members being based on or weighted by the amount, type, degree, or significance of interactions between them and the flow of communications between members, etc. In some embodiments, this may have the form of a tree structure with nodes representing employees being connected by branches. The size, color, or number of branches may indicate characteristics of the interactions between the connected nodes (e.g., the frequency, importance, or topic of the interactions, etc.). For some purposes this provides a more accurate and realistic view of how information and communications move within an organization. It may also be used to provide insight into the strength of certain relationships, the degree of involvement of certain people or groups in implementing policies or in making decisions, or the relative importance of certain communication channels.

Abstract: Polypeptides comprising a C3b binding region and a C3d inactivating region are disclosed, as well as nucleic acids and vectors encoding proteolytic such polypeptides. Also disclosed are cells and compositions comprising such polypeptides, and uses and methods using the same.

Abstract: Aspects of the present disclosure relate to enhancing virtual reality safety. A virtual reality (VR) boundary associated with a VR system can be determined, the VR boundary dictating a safe play area for a VR user using the VR system. A location of a first device can be determined. A determination can be made that the location of the first device is within the VR boundary. In response to a determination that the first device is within the VR boundary, the VR user can be alerted that the first device entered the VR boundary.

Abstract: A system and methods for generating an interaction-weighted visualization of an organization or group, with the relationships between members being based on or weighted by the amount, type, degree, or significance of interactions between them and the flow of communications between members, etc. In some embodiments, this may have the form of a tree structure with nodes representing employees being connected by branches. The size, color, or number of branches may indicate characteristics of the interactions between the connected nodes (e.g., the frequency, importance, or topic of the interactions, etc.). For some purposes this provides a more accurate and realistic view of how information and communications move within an organization. It may also be used to provide insight into the strength of certain relationships, the degree of involvement of certain people or groups in implementing policies or in making decisions, or the relative importance of certain communication channels.

Abstract: Systems, apparatuses, and methods for visualizing, navigating within, and interacting with data, typically organizational related data. In one embodiment, the invention may be implemented in conjunction with a business data processing system or platform. Such a system or platform may be a multi-tenant business data processing system that provides data storage and data processing capabilities for users. The data stored and/or processed may include one or more of ERP (Enterprise Resource Planning), CRM (Customer Relationship Management), HR/HCM (Human Resources/Human Capital Management), or financial business-related data.

Abstract: The present invention relates to a freezer and method for fabricating a freezer.