Abstract: Polypeptides comprising a C3b binding region and a C3d inactivating region are disclosed, as well as nucleic acids and vectors encoding such polypeptides. Also disclosed are cells and compositions comprising such polypeptides, and uses and methods using the same.

Abstract: Implementations generally relate to management of metadata groups and associated workflows. In some implementations, a method includes receiving a workflow request, wherein the workflow request includes information associated with a metadata group. The method further includes providing a workflow list of available workflows based on the metadata group. The method further includes receiving a selection of a workflow from the workflow list. The method further includes providing the workflow and a form associated with the workflow.

Abstract: Agents for reducing the gene and/or protein expression of FH family proteins are disclosed. Also disclosed are articles encoding the agents and methods of using the agents, including in therapeutic and prophylactic methods.

Abstract: Methods for detecting and determining the level of complement proteins are disclosed, in particular using mass spectrometry. Also disclosed are methods of identifying subjects having or at risk of developing a complement-related disorder, and methods of treating the same.

Abstract: Methods of identifying subjects having complement-related disorders, or at risk of such disorders, are disclosed. Also disclosed are methods for selecting subjects for treatment with complement-targeted therapies, and methods of treatment of subjects with such therapies.

Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: Implementations generally relate to management of metadata groups and associated workflows. In some implementations, a method includes receiving a workflow request, wherein the workflow request includes information associated with a metadata group. The method further includes providing a workflow list of available workflows based on the metadata group. The method further includes receiving a selection of a workflow from the workflow list. The method further includes providing the workflow and a form associated with the workflow.

Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: A refrigerator fan device, comprising: a fan motor (10) which has a fan rotor (12) and which can be provided in an air duct between an air inlet (16), a refrigerator heat exchanger (15), and/or a refrigerator compressor (14) and an air outlet (18) on or in a refrigerator housing (20, 22), said fan motor (10) being connectable to a unit of the refrigerator, via electrical supply and/or control lines, wherein the fan motor (10) is realized as a brushless speed-controllable DC motor whose operating speed is or can be controlled as a function of an operating and/or used cooling space temperature signal of, the assigned or assignable refrigerator compressor.

Abstract: The present disclosure includes a composite tube with a stranded wire and a method for making same. The method may include providing a core and providing at least one layer comprising electrically conductive material. The method may further include applying the at least one layer around at least a portion of the core. The method may further include providing the stranded wire comprising an embedded portion. The method may further include embedding the embedded portion of the stranded wire within the at least one layer of electrically conductive material.

Abstract: Concepts and technologies are described herein for cache management. In accordance with the concepts and technologies disclosed herein, the server computer can be configured to communicate with a client device configured to execute a cache module to maintain a cache storing data downloaded from and/or uploaded to the server computer by the client device. The server computer can be configured to receive requests for data stored at the server computer. The server computer can be configured to respond to the request with hashes that correspond to the requested data. The client device can search the cache for the hashes, obtain the data from the cache if the hashes are found, and/or download the data from the server computer if the hashes are not found. The client device also can be configured to update the cache upon uploading the data to the server computer.

Abstract: Methods for determining whether a subject is at risk of developing a complement-related disorder are disclosed. Also disclosed are complement-targeted therapeutics for treating a complement-related disorder, in particular agents that decrease the level of FHR-4.

Abstract: Systems and methods for device authentication are disclosed. In one embodiment, a method for authenticating a device includes, at a financial institution comprising an acquirer portion, a payment network portion, and an issuer portion: (1) the acquirer portion receiving, from the merchant, a least one mobile device credential and a payment credential that were received electronically from a mobile payment application executed by a mobile electronic device in conjunction with a transaction, the acquirer portion further receiving transaction data for the transaction from the merchant; (2) the issuer portion receiving, via the payment network portion, the mobile device credentials, the payment credentials, and transaction data from the acquirer portion; and (3) at least one computer processor at the issuer portion identifying and authenticating the customer based on the mobile device credentials and the payment credential.

Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.

Abstract: Aspects of the present disclosure relate to enhancing virtual reality safety. A virtual reality (VR) boundary associated with a VR system can be determined, the VR boundary dictating a safe play area for a VR user using the VR system. A location of a first device can be determined. A determination can be made that the location of the first device is within the VR boundary. In response to a determination that the first device is within the VR boundary, the VR user can be alerted that the first device entered the VR boundary.

Abstract: Systems, apparatuses, and methods for visualizing, navigating within, and interacting with data, typically organizational related data. In one embodiment, the invention may be implemented in conjunction with a business data processing system or platform. Such a system or platform may be a multi-tenant business data processing system that provides data storage and data processing capabilities for users. The data stored and/or processed may include one or more of ERP (Enterprise Resource Planning), CRM (Customer Relationship Management), HR/HCM (Human Resources/Human Capital Management), or financial business-related data.

Abstract: A system and methods for generating an interaction-weighted visualization of an organization or group, with the relationships between members being based on or weighted by the amount, type, degree, or significance of interactions between them and the flow of communications between members, etc. In some embodiments, this may have the form of a tree structure with nodes representing employees being connected by branches. The size, color, or number of branches may indicate characteristics of the interactions between the connected nodes (e.g., the frequency, importance, or topic of the interactions, etc.). For some purposes this provides a more accurate and realistic view of how information and communications move within an organization. It may also be used to provide insight into the strength of certain relationships, the degree of involvement of certain people or groups in implementing policies or in making decisions, or the relative importance of certain communication channels.

Abstract: Systems and methods for device authentication are disclosed. In one embodiment, a method may include (1) an acquirer portion receiving a device credential and a payment credential that were received from the payment application in conjunction with a transaction, the acquirer portion further receiving transaction data for the transaction from the merchant; (2) the acquirer portion performing a first validation assessment on the transaction based on the transaction data and first data retrieved from a first data source; (3) the payment network portion performing a second validation assessment on the transaction based on the transaction data and second data retrieved from a second data source; and (4) the issuer portion identifying and authenticating the customer based on the device credential, the payment credential, and at least one of the first validation assessment and the second validation assessment.

Abstract: Polypeptides comprising a C3b binding region and a C3d inactivating region are disclosed, as well as nucleic acids and vectors encoding proteolytic such polypeptides. Also disclosed are cells and compositions comprising such polypeptides, and uses and methods using the same.