Patents by Inventor Simon Francis Brereton
Simon Francis Brereton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148979Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.Type: ApplicationFiled: January 16, 2024Publication date: May 9, 2024Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Publication number: 20240042137Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.Type: ApplicationFiled: October 16, 2023Publication date: February 8, 2024Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Patent number: 11819670Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.Type: GrantFiled: December 18, 2020Date of Patent: November 21, 2023Assignee: Sanofi-Aventis Deutschland GMBHInventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Publication number: 20230140568Abstract: An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case, a carrier subassembly comprising a tubular carrier slidably arranged inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector also has, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for advancing the needle beyond a proximal end of the auto-injector, and a trigger button is used for releasing the control spring on actuation.Type: ApplicationFiled: December 22, 2022Publication date: May 4, 2023Inventors: Simon Francis Brereton, Thomas Kemp, Rosemary Burnell, Matthew Ekman
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Publication number: 20230082328Abstract: An auto-injector for administering a dose of a liquid medicament includes an elongate tubular case and a carrier subassembly including a tubular carrier slidably arranged inside the case. The carrier is adapted to contain a syringe with a hollow injection needle, a drive spring, and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier, wherein the drive spring acts between the carrier and the plunger, wherein the plunger, in an initial state, is locked to the carrier by a ramped engagement to the carrier and by being prevented from rotating out of this ramped engagement, depending on a relative longitudinal position of the carrier in the case, and wherein the plunger is arranged to be released for rotating out of the ramped engagement.Type: ApplicationFiled: September 26, 2022Publication date: March 16, 2023Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Patent number: 11559630Abstract: An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case, a carrier subassembly comprising a tubular carrier slidably arranged inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector also has, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for advancing the needle beyond a proximal end of the auto-injector, and a trigger button is used for releasing the control spring on actuation.Type: GrantFiled: August 13, 2019Date of Patent: January 24, 2023Assignee: Sanofi-Aventis Deutschland GMBHInventors: Simon Francis Brereton, Thomas Kemp, Rosemary Burnell, Matthew Ekman
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Patent number: 11484655Abstract: An auto-injector includes a chassis and a carrier subassembly. The carrier subassembly includes a carrier arranged inside a case, a drive spring, a plunger comprising a ramp member, the plunger configured to be pushed in a proximal direction by the drive spring, and a ramp attached to the carrier, wherein the ramp member on the plunger in an initial state is locked to the ramp on the carrier to form a ramped engagement to the carrier, the plunger prevented from rotating out of the ramped engagement depending on a relative longitudinal position of the carrier relative to the chassis, wherein the plunger is arranged to be released and to rotate out of the ramped engagement upon the carrier translating a pre-defined distance in a proximal direction relative to the chassis.Type: GrantFiled: October 29, 2019Date of Patent: November 1, 2022Assignee: Sanofi-Aventis Deutschland GMBHInventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Publication number: 20210213206Abstract: A detent mechanism for controlling translation between two components in a longitudinal direction includes a resilient beam on one of the components and a rhomboid ramp member on the other component. The resilient beam is essentially straight when relaxed and has a first beam head and is arranged to interact in a ramped engagement with respectively one of two ramps. Each ramp is on one longitudinal side of the rhomboid ramp member such that application of a translative force between the components in one longitudinal direction with the first beam head engaged to one of the ramps in a first state deflects the resilient beam in one transversal direction and such that application of a translative force between the components in the other longitudinal direction with the first beam head engaged to the other one of the ramps deflects the resilient beam in the other transversal direction.Type: ApplicationFiled: March 25, 2021Publication date: July 15, 2021Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Publication number: 20210100961Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.Type: ApplicationFiled: December 18, 2020Publication date: April 8, 2021Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Patent number: 10960142Abstract: A detent mechanism for controlling translation between two components in a longitudinal direction includes a resilient beam on one of the components and a rhomboid ramp member on the other component. The resilient beam is essentially straight when relaxed and has a first beam head and is arranged to interact in a ramped engagement with respectively one of two ramps. Each ramp is on one longitudinal side of the rhomboid ramp member such that application of a translative force between the components in one longitudinal direction with the first beam head engaged to one of the ramps in a first state deflects the resilient beam in one transversal direction and such that application of a translative force between the components in the other longitudinal direction with the first beam head engaged to the other one of the ramps deflects the resilient beam in the other transversal direction.Type: GrantFiled: March 13, 2018Date of Patent: March 30, 2021Assignee: Sanofi-Aventis Deutschland GMBHInventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Patent number: 10894132Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.Type: GrantFiled: February 15, 2018Date of Patent: January 19, 2021Assignee: Sanofi-Aventis Deutschland GMBHInventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Publication number: 20200078524Abstract: An auto-injector includes a chassis and a carrier subassembly. The carrier subassembly includes a carrier arranged inside a case, a drive spring, a plunger comprising a ramp member, the plunger configured to be pushed in a proximal direction by the drive spring, and a ramp attached to the carrier, wherein the ramp member on the plunger in an initial state is locked to the ramp on the carrier to form a ramped engagement to the carrier, the plunger prevented from rotating out of the ramped engagement depending on a relative longitudinal position of the carrier relative to the chassis, wherein the plunger is arranged to be released and to rotate out of the ramped engagement upon the carrier translating a pre-defined distance in a proximal direction relative to the chassis.Type: ApplicationFiled: October 29, 2019Publication date: March 12, 2020Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Patent number: 10556064Abstract: An auto-injector for administering a dose of a liquid medicament has a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. There is also a trigger button arranged distally or laterally in or on the case, a control spring arranged around the carrier, and a needle extension control mechanism for coupling a proximal end of the control spring to either the carrier for advancing it for needle extension or to the chassis for needle retraction depending on the relative axial position of the carrier and the chassis.Type: GrantFiled: April 5, 2017Date of Patent: February 11, 2020Assignee: Sanofi-Aventis Deutschland GMBHInventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Patent number: 10518041Abstract: An Injection device for administering a dose of liquid medicament to patient comprises—a syringe containing the dose of medicament—a hollow injection needle adapted to penetrate skin of the patient,—a stopper translatably disposed within syringe,—a plunger connectable to stopper and translatable in at least a proximal direction to displace stopper in the proximal direction and—a releasable noise component capable of, upon release, generating an audible and/or tactile feedback. The proximal displacement of stopper causes the dose of the medicament to be expelled through the hollow injection needle. The noise component is released when the plunger reaches a position relative to the syringe in which stopper is located in proximity of a proximal end of the syringe. The released noise component impacts on at least one component of the injection device to generate the audible and/or tactile feedback indicating the end of the injection.Type: GrantFiled: October 9, 2015Date of Patent: December 31, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Publication number: 20190358405Abstract: An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case, a carrier subassembly comprising a tubular carrier slidably arranged inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector also has, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for advancing the needle beyond a proximal end of the auto-injector, and a trigger button is used for releasing the control spring on actuation.Type: ApplicationFiled: August 13, 2019Publication date: November 28, 2019Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Patent number: 10471210Abstract: An auto-injector for administering a dose of a liquid medicament includes a case and a carrier subassembly with a carrier slidably arranged inside the case. The carrier can contain a syringe with a hollow injection needle, a drive spring and a plunger for forwarding drive spring load to a syringe stopper. The syringe can jointly, axially translate with the carrier. The drive spring acts between the carrier and the plunger. In an initial state, the plunger is locked to the carrier by a ramped engagement to the carrier and is prevented from rotating out of this engagement depending on a longitudinal position of the carrier in the case. The plunger can be released for rotating out of the ramped engagement when the needle reaches nearly a predefined injection depth on translation of the carrier in the proximal direction for advancing the needle beyond a proximal end of the auto-injector.Type: GrantFiled: March 7, 2017Date of Patent: November 12, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Patent number: 10413668Abstract: An auto-injector for administering a dose of a liquid medicament includes an elongate case arranged to be held by a user, a tubular chassis telescopable in the case and biased against the case so as to protrude from the case, a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, and a trigger button which is initially abutted against the case thus preventing actuation. The chassis is arranged to translate into the case against the bias when pressed against an injection site. The trigger button is initially coupled to the chassis such that the trigger button emerges from the case when the chassis is being pressed against the injection site to allow actuation by being translated towards the case for starting an injection cycle.Type: GrantFiled: February 15, 2017Date of Patent: September 17, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
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Patent number: D888225Type: GrantFiled: April 30, 2018Date of Patent: June 23, 2020Assignee: Smith & Nephew Asia Pacific Pte. LimitedInventors: Ben Alan Askem, Simon Francis Brereton, Matthew Keith Fordham, Mark Richard Hesketh, Mark Edward Jones, Hannah Bailey Sidebottom, Robert Simmonds
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Patent number: RE47903Abstract: An auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe with an injection needle, a plunger and a stopper for sealing a syringe barrel and a drive means releasably coupled to the plunger for advancing the syringe in the proximal direction (P) for needle insertion into an injection site and for displacing the dose of medicament (M) into the injection site. The drive means is arranged to be decoupled from the plunger for advancing a needle shroud to a safe position (PS) to surround the injection needle after the injection. According to the invention, the drive means bears against a thrust collar arranged to be releasably coupled to the plunger through a ramped engagement of a first tongue and a first recess so as to rotate the thrust collar on translation in proximal direction (P).Type: GrantFiled: February 26, 2018Date of Patent: March 17, 2020Assignee: Sanofi-Aventis Deutschland GMBHInventors: Yannick Hourmand, Simon Francis Brereton, Matthew Ekman
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Patent number: RE48593Abstract: An auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe with an injection needle, a plunger and a stopper for sealing a syringe barrel and a drive means releasably coupled to the plunger for advancing the syringe in the proximal direction (P) for needle insertion into an injection site and for displacing the dose of medicament (M) into the injection site. The drive means is arranged to be decoupled from the plunger for advancing a needle shroud to a safe position (PS) to surround the injection needle after the injection. According to the invention, the drive means bears against a thrust collar arranged to be releasably coupled to the plunger through a ramped engagement of a first tongue and a first recess so as to rotate the thrust collar on translation in proximal direction (P).Type: GrantFiled: January 28, 2020Date of Patent: June 15, 2021Assignee: Sanofi-Aventis Deutschland GMBHInventors: Yannick Hourmand, Simon Francis Brereton, Matthew Ekman