Abstract: The present invention inter alia relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present invention.

Abstract: The invention relates to a dispense interface for use with a drug delivery device with an inner body and with a lockout element, wherein the lockout element is coupled to the inner body, wherein the lockout element is movable from a receptive condition to a locked condition, wherein in the receptive condition the dispense interface is attachable to the drug delivery device, wherein in the locked condition the dispense interface is not-attachable to the drug delivery device and wherein the lockout element is configured to move from the receptive condition to the locked condition when said dispense interface is attached to and detached from said drug delivery device. The invention solves the technical problem of reducing the risk of reuse of a dispense interface, after it has already been used with a drug delivery device.

Abstract: The invention faces the technical problem of providing a tight connection between a tube and an dispense interface, while at the same time the biocompatibility of the connection can be improved. The technical problem is solved by an apparatus comprising a tube configured to guide a medium and a dispense interface. The tube comprises a first opening and a second opening, while the dispense interface comprises a recess. The recess has a first opening and a second opening and the tube is at least in part inserted into the recess. The tube is permanently affixed to the dispense interface by a combination of an interference fit and an adhesive, such that the interference fit prevents the adhesive from contaminating the medium.

Abstract: The invention faces the technical problem of reducing the uncertainty over exact doses ejected from a medical device and at the same time providing a homogeneous, but controlled mixture of at least two fluids while a simple production should be maintained. A medical device comprising a first valve, a second valve, a first pre-valve ullage, a second pre-valve ullage, a post-valve ullage with a first end and a second end and a needle is presented. The first pre-valve ullage is connected to the post-valve ullage by the first valve and the second pre-valve ullage is connected to the post-valve ullage by the second valve. A first fluid is guidable from the first pre-valve ullage to the post-valve ullage and a second fluid is guidable from the second pre-valve ullage to the post-valve ullage.

Abstract: The invention is related to a manifold comprising at least two valve receptacles, further comprising a fluid groove arrangement comprising at least two fluid grooves, wherein a first fluid groove of the at least two fluid grooves has a starting point near a first valve receptacle of the at least two valve receptacles and an end point near a second valve receptacle of the at least two valve receptacles and wherein a second fluid groove of the at least two fluid grooves has a starting point near a second valve receptacle of the at least two valve receptacles. The invention is further related to an apparatus comprising a manifold of the aforementioned kind and further comprising an inner body of a dispense interface.

Abstract: The invention relates to a dispense interface for use with a drug delivery device with an inner body and with a lockout element, wherein the lockout element is coupled to the inner body, wherein the lockout element is movable from a receptive condition to a locked condition, wherein in the receptive condition the dispense interface is attachable to the drug delivery device, wherein in the locked condition the dispense interface is not-attachable to the drug delivery device and wherein the lockout element is configured to move from the receptive condition to the locked condition when said dispense interface is attached to and detached from said drug delivery device. The invention solves the technical problem of reducing the risk of reuse of a dispense interface, after it has already been used with a drug delivery device.

Abstract: The invention is related to an apparatus comprising a dispense interface for use with a drug delivery device, the dispense interface comprising a lockout element being arranged at least partially between an outer body of the dispense interface and an inner body of the dispense interface and wherein the lockout element is configured to be removeably maintained in a first position, such that when the dispense interface is first attached and then removed from said drug delivery device, the lockout element moves into a second position, wherein the lockout element in the second position is configured to prevent said dispense interface from being reattached to a drug delivery device.

Abstract: A dispense interface for use with a drug delivery device. The dispense interface comprises a main outer body and an inner body. The inner body may be configured for connection to a drug delivery device and defines a first reservoir and a second reservoir. A first piercing needle is in fluid communication with the first reservoir and positioned for piercing a first cartridge of a drug delivery device. A second piercing needle is provided and in fluid communication with the second reservoir and positioned for piercing a second cartridge contained with a drug delivery device. A manifold is positioned adjacent the inner body and comprises a fluid groove arrangement. A valve arrangement is positioned between the inner body and the manifold and controls fluid communication of a first fluid contained in the first cartridge and a second fluid contained in the second cartridge by way of the fluid groove arrangement to a holding chamber.

Abstract: A drug delivery device having a spring element that provides dispense assistance. The drug delivery device includes a variable dose setting mechanism, a fixed dose setting mechanism, and a mechanical coupling having a spring element. The variable dose setting mechanism is operably coupled to a first reservoir holding a first medicament, and the variable dose setting mechanism comprises a dose setter. The fixed dose setting mechanism is operably coupled to a second reservoir holding a second medicament. The mechanical coupling operably couples the variable dose setting mechanism and the fixed dose setting mechanism. Further, the variable dose setting mechanism is configured to set a variable dose of the first medicament upon activation of the dose setter, and the fixed dose setting mechanism is configured to set a fixed dose of the second medicament during variable dose setting.

Abstract: A medicated module attachable to a drug delivery device comprising a connecting body configured for attachment to the drug delivery device. A first needle held within a first needle hub of the connecting body and a second needle fixed within a second needle hub of the connecting body. A recess within the connecting body defining a reservoir. The reservoir containing at least one dose of a medicament and configured for fluid communication with the first needle. The connecting body further comprises a lockout feature that prevents the medicated module from being reconnected to the drug delivery device after the medicated module has been connected to the drug delivery device a first time.

Abstract: A dose setting mechanism for a drug delivery device. The mechanism may comprise a drug delivery device housing. A dose dial component is positioned in the housing and rotatable during dose setting and dose delivery. A split threaded insert is in threaded engagement with the dose dial component. The insert can transform from a first configuration to a second configuration when the dose dial component is rotated. In one dose setting mechanism arrangement, the first configuration may comprise a first open configuration and the second configuration may comprise a second closed configuration.

Abstract: A medicated module (100) is attachable to a drug delivery device (102). The medicated module (100) includes a housing (104) having a proximal end and a distal end, the proximal end has a connector (110) configured for attachment to a drug delivery device (102). The distal end contains a shuttle (112). A first needle (114) is fixed in the housing (104) and a second needle (116) is fixed in the shuttle (112). The medicated module (100) also includes a reservoir (118) in the housing (104) comprising a medicament (12). Further, the medicated module (100) includes a guard assembly (122) positioned in the housing (104) and configured to move in an axial direction during application to an injection site. Preferably, the medicated module (100) is locked out after at least two injections of the medicament (105) contained in the drug delivery device (102).

Abstract: An improved pushchair frame (10) of a type that can be collapsed for ease of transport or storage etc. The frame comprising a push/pull handle (12), a front wheel frame (14) on which at least one front wheel (16) is rotatably mounted and a rear wheel frame (18) on which at least one rear wheel (20) is rotatably mounted. The frame comprising a seat mounting yoke (22) to which the front and rear wheel frames are coupled, at least one of the front and rear wheel frames being pivotably coupled to the yoke, the frames having an operating position in which they are spaced from one another and a stowed position in which they are generally adjacent one another. The seat mounting yoke is rotatable, relative to at least one of the front and rear wheel frames, between an operating position and a stowed position in which the yoke is located generally adjacent one of the front and rear wheel frames. A retaining means maintains the yoke and the front and rear wheel frames in their operating position.

Abstract: A pushchair seat (10) comprising a seat back (18) mounted for pivotable movement relative to a seat base (20). A bumper bar (14) is pivotably coupled to and carried by the seat (10) and is moveable between a stowed position generally adjacent to the seat base (20) and a deployed position spaced from the seat back (18) and the seat base (20). Drive mechanisms (16) are provided at each end of the bumper bar (14) and comprise a selectively engageable coupling mechanism in the form of a clutch mechanism (30, 32) and a control mechanism (34, 56, 58). The coupling mechanism couples movement of the seat back (18) between its stowed position and its operating position into a corresponding movement of the bumper bar (14) between its stowed position and its deployed position.

Abstract: A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle. The medicated module is user selectable so that it will deliver a priming dose of a primary medicament or both the primary and secondary medicaments. The module also contains a needle guard that locks after dose delivery. The needle guard prevents accidental needle sticks before and after an injection. A locking collar rotates during use as an inner protrusion follows three paths of a track located on the outer surface of a body housing. When the inner facing protrusion is in the third path, it encounters a hard stop and a rotational bias that locks the guard from further refraction and thus covers the sharp distal end of the needle.

Abstract: A first input member (6) and a second input member (7) are arranged along a first axis (4) and coupled in such a manner that a movement of the first input member along the first axis is converted into a rotational movement of the second input member with respect to the body (1). A first output member (8) and a second output member (9) are arranged along a second axis (5) and coupled in such a manner that a rotational movement of the first output member is converted into a movement of the second output member along the second axis with respect to the body. The second input member and the first output member are releasably rotationally coupled.

Abstract: According to one aspect, a resettable drive assembly for a drug delivery device is provided for. The resettable drive assembly may comprise a housing having a proximal end and a distal end, a piston rod being rotatable with respect to the housing and being axially displaceable with respect to the housing between a proximal start position and a distal end position, a drive member for distally displacing the piston rod towards the end position when dispensing a dose, and a stop member. The drive assembly may be configured such that the drive member is operable to interact with the piston rod for forming an unlockable first interlock, the first interlock being operable to block proximal movement of the piston rod with respect to the drive member. The drive assembly may be configured such that the stop member is operable to interact with the piston rod for forming an unlockable second interlock, the second interlock being operable to block proximal movement of the piston rod with respect to the housing.