Abstract: A patch delivery device includes a bottom housing part, a delivery element for subcutaneous delivery of a liquid to a patient, an adhesive patch for attaching the bottom housing part to the skin of the patient, a capacitive sensor with an electrode configuration including a plurality of skin contact sensitive electrodes, and a release liner covering a patient-side adhesive layer of the adhesive patch prior to adhering to the patient's skin. The release liner includes an electrically conductive area extending over at least a portion of the electrode configuration of the capacitive sensor before being removed from the adhesive patch. Providing the release liner with a conductive area gives rise to a discernible change in capacitive response of the sensor electrodes upon release liner removal that enables sensing a removal of a release liner covering a patient-side adhesive layer prior to attachment to the skin of a patient.

Abstract: Dosing device for an administration device with a limiting mechanism containing: a dosing sleeve with a first stop and a stop wheel with a second stop means adapted to continually and proportionally follow a movement of the dosing sleeve during dosing movements. During an ejection movement, there is no relative movement between dosing sleeve and stop wheel. The first stop and the second stop each describe a path curve by their movements such that the two path curves intersect in one point and the stops contact one another and tilt the stop wheel, thereby blocking the dosing movement of the dosing sleeve. The stop wheel comprises first and third sloped surfaces that may form first and second gear guidances with a clutch thereby returning the stop wheel to a non-tilted position during up or down dosing movements when the stops do not contact another.

Abstract: A patch delivery device includes a bottom housing part, a delivery element for subcutaneous delivery of a liquid to a patient, an adhesive patch for attaching the bottom housing part to the skin of the patient, a capacitive sensor with an electrode configuration including a plurality of skin contact sensitive electrodes, and a release liner covering a patient-side adhesive layer of the adhesive patch prior to adhering to the patient's skin. The release liner includes an electrically conductive area extending over at least a portion of the electrode configuration of the capacitive sensor before being removed from the adhesive patch. Providing the release liner with a conductive area gives rise to a discernible change in capacitive response of the sensor electrodes upon release liner removal that enables sensing a removal of a release liner covering a patient-side adhesive layer prior to attachment to the skin of a patient.

Abstract: A drug delivery system includes a drug delivery device for dispensing a drug from a reservoir with a device housing extending in an axial direction, a movable dispensing member, a magnetic element with a permanent magnetization coupled the dispensing member, and an electronic module for monitoring a dispensing process executed by the drug delivery device and releasably attachable to the device housing. The electronic module includes a module body, a magnetic field sensor unit and a controller. The sensor unit is adapted to measure an absolute rotational position and an absolute axial position of the magnetic element. The controller is configured to determine on basis of both the absolute rotational and the absolute axial position a fill level or a total amount of dispensed drug.

Abstract: A pre-assembled reservoir unit for attachment to a drive unit of a drug delivery device includes a reservoir, a reservoir holder and a mechanism holder defining a longitudinal axis and connected to the reservoir holder. The mechanism holder includes a housing connecting portion for coaxially attaching the mechanism holder to a housing of the drive unit along the longitudinal axis. The reservoir unit further includes a plunger rod that is in threaded or splined engagement with the mechanism holder.

Abstract: A drug delivery device for dispensing a drug from a reservoir includes a drive unit including an electronic control circuit and a coupling portion, and a reservoir unit including the reservoir with the drug and attachable to the coupling portion. The drive unit includes a plurality of switching elements operatively coupled to the control circuit, and the reservoir unit includes at least one actuation element adapted to selectively switch at least one switching element of the plurality of switching elements when the reservoir unit is attached to the drive unit. A control signal indicative of the reservoir or the drug is generated based on the switched switching element and sent to the control circuit.

Abstract: A method for monitoring a dispensing process of a liquid drug with a drug delivery device involves gradually increasing a motor drive current for a motor of the drug delivery device; measuring, by a sensor, a position or movement of an output member movable by the motor; determining a minimal motor drive current required to initially move the output member from standstill; and determining, from an evolution of successively determined minimal motor drive current values, a delivery device operation status.

Abstract: The present disclosure relates to a drug delivery arrangement including a drug delivery device for dispensing a liquid drug from a reservoir an electronic module. The delivery device includes a device housing and a movable member. The electronic module is releasably attachable to the device housing and includes a module housing, an actuator and an engaging member movable, by the actuator, relative to the module housing. The engaging member can be brought into engagement with the movable member such that a movement of one of the engaging member or the movable member causes a movement of the other of the movable member or the engaging member when the electronic module is attached to the drug delivery device.

Abstract: The present disclosure relates to a modular injection system including a first injection device including a first reservoir unit comprising a reservoir filled with medication, a housing for holding the reservoir and a plunger rod adapted to advance a piston inside the reservoir to dispense the medication and first automatic drive unit releasably attachable to the reservoir unit and including an automatic drive member automatically driven by a power source and adapted to be releasably coupled to the plunger rod. The modular system further comprises a second injection device including a second reservoir unit and a manual drive unit connected to the reservoir unit and including a manual drive member manually driven and connected to a plunger rod of the second reservoir unit. The first and second reservoir unit are identical.

Abstract: An autoinjector having a housing for receiving a product container, a propelling member, a drive for automatically discharging a liquid product, a needle-guard spring for pretensioning a needle-guard sleeve, a grid with a multiplicity of latch elements arranged along the longitudinal direction, and an engagement element which, by engagement in the grid, blocks a discharging movement of the propelling member. A control element of the autoinjector interacts with the engagement element via a control cam such that, when the control element moves in the distal direction by the needle-guard spring, the engagement element is brought into engagement with the grid. Since the force of the needle-guard spring is used for the engagement, the engagement element can be mounted without specific elastic force acting in an engagement direction, and can also be mounted in an articulated manner and/or in a manner limited to pure guidance in the engagement direction.

Abstract: An electronic add-on module for an injection device includes a longitudinal axis and a discharge button arranged at a proximal end and configured to be movable in a distal direction along the longitudinal axis for discharging a liquid medication out of a container of the injection device. The add-on module includes a sensor unit, a receiving region adapted to the shape of the housing of the injection device for placing on along the longitudinal axis thereof, and a holding mechanism configured to releasably secure the add-on module against moving axially relative to the injection device. The receiving region is configured such that the discharge button can be accessed or contacted when the add-on module is on the injection device. The add-on module comprises a release element configured to be moved solely on a plane perpendicular to the longitudinal axis in a release movement for releasing the holding mechanism.

Abstract: A segmented piston rod for an injection device includes multiple segments joined together via a hinge located on one side of each segment. The piston rod can be bent in one direction by articulating subsequent hinges while an axial force can be transmitted by the segmented piston rod to the stopper when the subsequent hinges are closed and the segments abut each other opposite to the one side of the hinge. The segmented piston rod is secured against rotation relative to the housing around the longitudinal axis of the segmented piston rod. The segmented piston rod has a last element which abuts the stopper in the reservoir and a first segment which is opposite to the last segment. The first segment is includes an internal thread matching an external thread of a drive sleeve and rotation of the drive sleeve advances the piston rod towards the stopper of the reservoir.

Abstract: An injection device for dispensing a dose of a product by manually advancing a piston rod includes a dosing and dispensing mechanism having a housing with a longitudinal axis, a dosing sleeve mounted in the housing for adjusting and correcting the dose, a housing insert fixed to the housing and arranged inside the dosing sleeve, and a coupling sleeve mounted in the housing for driving the piston rod. For setting and correcting a dose, the dosing sleeve is rotatable relative to the coupling sleeve, and for dispensing the dose, the dosing sleeve can be coupled to the coupling sleeve in a rotationally fixed manner. In this case, the coupling sleeve has a locking element which can interact with the housing insert so that the coupling sleeve can be rotated in a first direction of rotation and cannot be rotated in a second direction of rotation relative to the housing insert.

Abstract: A dosing system for an injection device for dispensing a dose of a product includes a housing having a longitudinal axis, a dose-setting element, a holding element and a coupling sleeve for driving a driving device for dispensing the dose. The dose-setting element, holding element, and coupling sleeve may be accommodated in the housing. To set and correct the dose, the dose-setting element and the coupling sleeve move in the direction of the longitudinal axis relative to the housing, and the coupling sleeve may be held the holding element rotationally fixed by relative to the housing. To dispense the dose, the coupling sleeve may rotate relative to the housing, the dosing system including a guide in the housing, in which guide the holding element may be displaced in the direction of the longitudinal axis relative to the housing and be guided in a rotationally fixed manner relative to the housing.

Abstract: A coupling mechanism for a medication delivery device includes a first part axially fixed relative to a housing and rotatable around a longitudinal axis of the first part, the first part having a gearing engagement to a second part arranged along the longitudinal axis, the gearing engagement having a first frictional resistance. The second part axially moveable along the longitudinal axis, and directly or indirectly in a friction fit engagement with the housing, which has a second frictional resistance. The first frictional resistance being below the second frictional resistance such that a rotation of the first part in a first direction axially longitudinally moves the second part away from the first part and a rotation in a second direction, opposite to the first rotation direction, reduces the axial distance between the first and second part and/or axially moves the second part into coupling abutment with the first part.

Abstract: Dosing device for an administration device with a limiting mechanism containing: a dosing sleeve with a first stop and a stop wheel with a second stop means adapted to continually and proportionally follow a movement of the dosing sleeve during dosing movements. During an ejection movement, there is no relative movement between dosing sleeve and stop wheel. The first stop and the second stop each describe a path curve by their movements such that the two path curves intersect in one point and the stops contact one another and tilt the stop wheel, thereby blocking the dosing movement of the dosing sleeve. The stop wheel comprises first and third sloped surfaces that may form first and second gear guidances with a clutch thereby returning the stop wheel to a non-tilted position during up or down dosing movements when the stops do not contact another.

Abstract: A needle insertion and retraction mechanism for a medication delivery device includes a housing and a needle carrier holding a needle guided by the housing and moved along a needle axis. A first spring member is adapted to move the carrier in an insertion direction. A second spring member is adapted to retract the carrier in a retraction direction, opposite the insertion direction. A control element, linearly guided by the housing, moves transversely to the needle axis from a starting position, via a needle insertion release position, to a needle retraction release position. When the control element is in its starting position, the control element is coupled to the carrier to prevent the carrier from moving in the insertion direction. When the control element is in the release position, the control element is decoupled from the carrier and the first spring member drives the carrier in the needle insertion direction.

Abstract: An assembly for an injection or infusion device includes i) a cartridge being closed by a septum and the surface of the septum being sterile and covered by a first continuous flexible strip, and ii) a fluid path unit comprising a cartridge holder and a fluid path compartment comprising a needle in an interior, the needle is configured to penetrate the septum of the cartridge through a passage in the fluid path compartment. The passage is closed by a second continuous flexible strip keeping the interior of the fluid path compartment in a sterile condition. The cartridge is inserted into the cartridge holder aligning the septum with the passage and sandwiching both strips between the septum and the fluid path compartment. Both strips may be simultaneously removable from the cartridge and fluid path compartment thereby, establishing a sterile connection between the septum and the interior of the fluid path compartment.

Abstract: A patch delivery device includes a bottom housing part, a delivery element for subcutaneous delivery of a liquid to a patient, an adhesive patch for attaching the bottom housing part to the skin of the patient, a capacitive sensor with an electrode configuration including a plurality of skin contact sensitive electrodes, and a release liner covering a patient-side adhesive layer of the adhesive patch prior to adhering to the patient's skin. The release liner includes an electrically conductive area extending over at least a portion of the electrode configuration of the capacitive sensor before being removed from the adhesive patch. Providing the release liner with a conductive area gives rise to a discernible change in capacitive response of the sensor electrodes upon release liner removal that enables sensing a removal of a release liner covering a patient-side adhesive layer prior to attachment to the skin of a patient.