Abstract: According to one embodiment, a cannula assembly may include a cannula module and an inserter module. In the pre-operational state the cannula is retracted with respect to the skin-contacting surface. In operational state the cannula projects beyond the skin-contacting surface. The inserter module may include an energy store and an activation mechanism. When the energy store is at least partially discharged, the stored potential energy is transformed to kinetic energy that moves the cannula from the pre-operational state to the operational state. The activation mechanism is triggerable from outside the cannula assembly with a trigger device. The activation mechanism prevents the energy store from being discharged before it is triggered by the trigger device, and enables the energy store to be discharged after it is triggered by the trigger device to force the cannula from the pre-operational state into the operational state.

Abstract: An infusion pump device comprising a primary liquid medicament reservoir, a pump with a secondary reservoir to retrieve medicament from the primary reservoir and to subsequently dose the medicament from the secondary reservoir in adjustable volumes (Vdose,i) to a downstream conduit and a control unit to control the operation of the infusion pump device is presented. For metering the volumes (Vdose,i), the control unit causes the infusion pump device to: (a) determine a maximum refill level (VC,max) for the secondary reservoir, based on external parameters, wherein the maximum refill level does not exceed the maximum capacity of the secondary reservoir; (b) fill the secondary reservoir with medicament from the primary reservoir to the maximum refill level (VC,max); (c) meter and convey the medicament volumes to the downstream conduit; (d) if the secondary reservoir becomes empty, refill the secondary reservoir as in step (b) and continue with step (c).

Abstract: An arrangement for introducing a liquid into the body of a patient or for withdrawing a liquid from the body of a patient, including a first structural part carrying a cannula for positioning in the body of the patient, and a second structural part with a connection port for detachably coupling a conduit for supplying or withdrawing a liquid, wherein the first and second structural parts are connected, can be rotated relative to each another and in relative rotational positions form a channel for introducing a liquid from the conduit to the cannula or for withdrawing a liquid from the cannula to the conduit, and whereby movement of the conduit for coupling and uncoupling is transverse to the longitudinal axis of the cannula.

Abstract: An arrangement for introducing a liquid into the body of a patient or for withdrawing a liquid from the body of a patient, including a first structural part carrying a cannula for positioning in the body of the patient, and a second structural part with a connection port for detachably coupling a conduit for supplying or withdrawing a liquid, wherein the first and second structural parts are connected, can be rotated relative to each another and in relative rotational positions form a channel for introducing a liquid from the conduit to the cannula or for withdrawing a liquid from the cannula to the conduit, and whereby movement of the conduit for coupling and uncoupling is transverse to the longitudinal axis of the cannula.

Abstract: An insertion head for medical or pharmaceutical applications includes a base having a lower side which can be positioned on organic tissue; an insertion means movably mounted by the base and insertable into the tissue; where the insertion means is movable relative to the base from a protective position in which a free end of the insertion means is short of the lower side of the base, into an insertion position in which the free end protrudes beyond the lower side; a handle which projects from the base and includes a first handle component and a second handle component movable relative to the base and the first handle component; and a coupling that transmits a movement of the second handle component into a movement of the insertion means.

Abstract: An insertion device for infusion sets, comprising a housing for enclosing an infusion set, a drive device for displacing the infusion set for insertion, wherein a portion of the drive device moves in an insertion direction, the movement being substantially friction-free relative to the housing.

Abstract: At least one dosing unit for an infusion pump is disclosed having a piston pump with a pump cylinder, a plunger arranged within said cylinder, and a plunger driving part provided for transmitting rotational torque from a driving unit to the plunger without itself being linearly displaced. The cylinder, the plunger and the plunger coupling element are coaxially arranged along a longitudinal axis and rotatable around said axis in regard to static parts of the dosing unit. The plunger and cylinder each having threads which engage with each other in such a way that a rotational movement of the plunger around the longitudinal axis results in a linear displacement of the plunger along the longitudinal axis. The dosing unit also having first coupling parts associated with the cylinder and second coupling parts associated with the plunger.

Abstract: At least one hand-held injection device for the metered injection of a liquid drug into a person's tissue is disclosed. The exemplary injection device comprises an elongated drug reservoir having a longitudinal reservoir axis (A), an elongated dosing unit having a dosing unit inlet, a dosing unit outlet, and a metering cavity, the dosing unit having a longitudinal dosing unit axis (A?), the elongated drug reservoir being fluidically coupled to the dosing unit inlet. The dosing unit and the drug reservoir are arranged such that the longitudinal dosing unit axis (A?) is in parallel alignment with the reservoir axis (A). The dosing unit structured to allow the flow of the liquid drug from the drug reservoir into the metering cavity via the dosing unit inlet, thus charging the metering cavity, and to subsequently discharge the metering cavity by dosing drug out of the metering cavity into the dosing unit outlet.

Abstract: Infusion systems for pumping fluid into a body of a user, and methods for providing infusion systems, are disclosed. The infusion systems include an infusion pump, wherein the infusion pump comprises an infusion pump housing including a cavity. A fluid storage is removably inserted into the cavity of the infusion pump housing wherein, the fluid storage comprises a cartridge and an adapter connected to the cartridge such that the adapter encases the cartridge, and an infusion set is removably connected to the fluid storage.

Abstract: Infusion systems for pumping fluid into a body of a user, and methods for providing infusion systems, are disclosed. The infusion systems include an infusion pump, wherein the infusion pump comprises an infusion pump housing including a cavity. A fluid storage is removably inserted into the cavity of the infusion pump housing wherein, the fluid storage comprises a cartridge and an adapter connected to the cartridge such that the adapter encases the cartridge, and an infusion set is removably connected to the fluid storage.

Abstract: An insertion device for applying an infusion set to the body of a patient, wherein the device has two actuation members which have to be actuated simultaneously to trigger an insertion movement by which a cannula of the infusion set is introduced into the body and wherein, in some embodiments, one of the actuation members is a securing slide including a contact face to be placed on the body of the patient, the securing slide being actuated by the insertion device being pressed, via the contact face, against the body of the patient.

Abstract: A device for inserting a cannula into tissue, including a cannula, a protective element which can accommodate said cannula, an operating element for moving the cannula out of the protective element, and a holder fixedly connected to the cannula. The invention encompasses a system for connecting a liquid supply to the cannula.

Abstract: An insertion head for medical or pharmaceutical applications includes a base having a lower side which can be positioned on organic tissue; an insertion means movably mounted by the base and insertable into the tissue; where the insertion means is movable relative to the base from a protective position in which a free end of the insertion means is short of the lower side of the base, into an insertion position in which the free end protrudes beyond the lower side; a handle which projects from the base and includes a first handle component and a second handle component movable relative to the base and the first handle component; and a coupling that transmits a movement of the second handle component into a movement of the insertion means.

Abstract: An infusion pump device comprising a primary liquid medicament reservoir, a pump with a secondary reservoir to retrieve medicament from the primary reservoir and to subsequently dose the medicament from the secondary reservoir in adjustable volumes (Vdose,i) to a downstream conduit and a control unit to control the operation of the infusion pump device is presented. For metering the volumes (Vdose,i), the control unit causes the infusion pump device to: (a) determine a maximum refill level (VC,max) for the secondary reservoir, based on external parameters, wherein the maximum refill level does not exceed the maximum capacity of the secondary reservoir; (b) fill the secondary reservoir with medicament from the primary reservoir to the maximum refill level (VC,max); (c) meter and convey the medicament volumes to the downstream conduit; (d) if the secondary reservoir becomes empty, refill the secondary reservoir as in step (b) and continue with step (c).

Abstract: An infusion pump device and method for filling a fluidic system of the infusion pump with liquid medicament prior to infusion operation is presented. A control unit causes the infusion pump to: (a) bring a pump to an initial state; (b) switch a valve to a first state connecting a secondary reservoir to a first conduit and a primary reservoir; (c) retrieve medicament from the primary reservoir; (d) switch the valve to a second state connecting the secondary reservoir to a second downstream conduit; (e) expel the secondary reservoir contents into the second downstream conduit; (f) switch the valve to the first state; (g) retrieve the primary reservoir medicament; (h) switch the valve to the second state; and (i) expel the secondary reservoir contents into the second downstream conduit by shifting a piston to the initial position.

Abstract: A dosing unit for an ambulatory infusion pump device is presented. The dosing unit comprises a cylinder pump with a cylinder and a piston arranged in the cylinder. The piston has a shaft with a first threaded segment interacting with a threaded portion of the cylinder and can be displaced along a longitudinal axis of the cylinder by rotating the piston in regard to the cylinder around the axis. Furthermore, the piston allows for the relative or absolute determination of the longitudinal and/or rotational displacement of the piston in regard to the cylinder. In one embodiment, the piston shaft comprises a second segment provided with optically detectable markings that allow the monitoring of the longitudinal and/or rotational displacement of the piston in regard to the cylinder.

Abstract: An insertion head for medical or pharmaceutical uses including a housing with a side that can be positioned on tissue and a penetrating device with a tip, the penetrating device carried by the housing in a protected orientation in which the housing covers the tip and a penetrating orientation in which the tip protrudes, wherein the penetrating orientation is angled relative to the protected orientation.

Abstract: An insertion head for medical or pharmaceutical applications includes a base having a lower side which can be positioned on organic tissue; an insertion means movably mounted by the base and insertable into the tissue; where the insertion means is movable relative to the base from a protective position in which a free end of the insertion means is short of the lower side of the base, into an insertion position in which the free end protrudes beyond the lower side; a handle which projects from the base and includes a first handle component and a second handle component movable relative to the base and the first handle component; and a coupling that transmits a movement of the second handle component into a movement of the insertion means.

Abstract: Devices and methods are disclosed which automatically reconstitute a drug, such as e.g., a lyophilized drug. A vial (30) containing the drug is fluidly coupled to a cartridge (12) containing a reconstitution liquid with a fluid conduit (14f), wherein an entry point is defined where the fluid conduit enters the vial (30). The device (10) automatically adjusts orientation of the vial (30) such that the entry point of the vial is gravitationally higher than the drug in the vial (30), and automatically transfers the reconstitution liquid out of the cartridge (12) and into the vial (30) to create a reconstituted drug. The device (10) also automatically adjusts the orientation of the vial (30) such that the entry point of the vial is gravitationally lower than the reconstituted drug, and automatically transfers the reconstituted drug from the vial (30) and into the cartridge (12).