Patents by Inventor Simon(Yu) Zhang

Simon(Yu) Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250161499
    Abstract: Provided herein are improved methods for preparing phospholipid formulations including phospholipid UCA formulations.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, Nhung Tuyet Nguyen, David C. Onthank, Tarakeshwar Vishwanath Anklekar, Charles Chester Van Kirk
  • Publication number: 20250161500
    Abstract: Novel compounds that find use as imaging agents within nuclear medicine applications (PET imaging) for imaging of cardiac innervation are disclosed. These PET based radiotracers may exhibit increased stability, decreased NE release (thereby reducing side effects), improved quantitative data, and/or high affinity for VMAT over prior radiotracers. Methods of using the compounds to image cardiac innervation are also provided. In some instances the compounds are developed by derivatizing certain compounds with 18F in a variety of positions: aryl, alkyl, a keto, benzylic, beta-alkylethers, gamma-propylalkylethers and beta-proplylalkylethers. Alternatively or additionally, a methyl group a is added to the amine, and/or the catechol functionality is either eliminated or masked as a way of making these compounds more stable.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Ajay Purohit, Thomas D. Harris, Heike S. Radeke, Simon P. Robinson, Ming Yu, David S. Casebier, Michael T. Azure
  • Publication number: 20250161556
    Abstract: A holding device configured to support medical containers includes a supporting plate having an upper surface, a lower surface, and a plurality of openings through the supporting plate configured to receive the medical containers. The holding device also includes a plurality of chimneys protruding from the upper surface and/or the lower surface of the supporting plate enclosing the openings, such that the plurality of chimneys guide insertion of the medical containers into the plurality of openings: and a plurality of reinforcing ribs protruding from the supporting plate extending between the plurality of chimneys. The plurality of reinforcing ribs include a first end portion extending radially from a first chimney of the plurality of chimneys and a second end portion extending radially from an adjacent second chimney of the plurality of chimneys.
    Type: Application
    Filed: February 23, 2023
    Publication date: May 22, 2025
    Inventors: Simon Rempfer, Mathilde Paulet, Jérémie Vaxelaire, Mario Flores, Anaïs Eymery
  • Publication number: 20250161588
    Abstract: A disposable syringe unit for an injection device adapted for releasable attachment to a reusable drive unit of the injection device includes a prefilled syringe with a reservoir and an injection needle, a syringe holder for holding the prefilled syringe, a cover member guided by guiding means thereby movable along the longitudinal axis relative to the syringe holder between a covering position in which the injection needle is covered and a retracted position in which the injection needle protrudes from the cover member, and a cap releasably attached to a distal end of the cover member or the syringe holder. Apart from the prefilled syringe, the syringe unit includes in total not more than three separate parts.
    Type: Application
    Filed: January 21, 2025
    Publication date: May 22, 2025
    Inventors: Simon Scheurer, Patrick Hostettler
  • Publication number: 20250165062
    Abstract: A head tracking system HTS (100, 200) and associated method and head worn assembly, configured to determine a head position and/or a head orientation of a user, the HTS comprising: one or more optical sensors (112) producing optical measurements; and one or more inertial sensors (104) producing inertial measurements; a processor configured, when the optical sensors fail to provide optical measurements to determine the head location and the head orientation of a user, to operate in a coasting mode using the inertial measurements from the one or more inertial sensors to determine the head location and the head orientation of a user, the processor configured to further: determine a figure of merit FOM (346) for coasting errors based on a combination of one or more of errors in an estimated inertial sensor bias, a random drift and noise of the inertial sensor and the inertial sensor gain and alignment errors; compare (348) the FOM with a threshold to determine whether the inertial measurements provide a valid or
    Type: Application
    Filed: June 1, 2023
    Publication date: May 22, 2025
    Applicant: BAE SYSTEMS PLC
    Inventors: Colin Richard Mills, Simon Trythall
  • Publication number: 20250165831
    Abstract: A method for performing quantum computations in a qudit processor. The qudit processor comprises a plurality of tracks, each comprising first, second and third locations. The method comprises: receiving qudits at manipulation devices inrespective tracks; manipulating the state of the qudits; transferring each qudit from the manipulation device to the first location in each track; enabling interaction between the first and second qudits; transferring each qudit from the first to second location; enabling interaction between the first and third qudits; transferring each qudit from the second to third location; and enabling interaction between the first and fourth qudits. The method further comprises either: transferring each qudit from the third to first location; and enabling interaction between the first and second qudits; or: transferring each qudit from the third location to the manipulation device in their respective tracks; and manipulating the state of each qudit.
    Type: Application
    Filed: March 6, 2023
    Publication date: May 22, 2025
    Inventors: Simon Benjamin, Zhenyu Cai
  • Publication number: 20250163212
    Abstract: Described herein is a method for making sulfonated polyphenylene polymers and the uses thereof. Such sulfonated polyphenylene polymers, and membranes prepared therefrom, have applications in fuel cells, water electrolyzers, water purification, battery products, and other electrochemical devices.
    Type: Application
    Filed: November 14, 2024
    Publication date: May 22, 2025
    Applicant: IONOMR INNOVATIONS INC.
    Inventors: Simon Cassegrain, Thomas Skalski
  • Publication number: 20250163641
    Abstract: The present invention relates to a method for providing a substrate on one face with a tint and a functional coloration, comprising the following steps (a) to (d): (a) supplying a substrate to be provided on one face with a tint and a functional coloration, the substrate comprising a semifinished part manufactured from transparent plastic and having a first main face and a second main face which lies opposite the first main face and has a convex shape, (b) applying a tint to both main faces of the substrate supplied in step (a), (c) applying a functional coloration to the second main face of the substrate provided with a tint on both main faces in step (b), the functional coloration being brought about by at least one photochromic dye and the at least one photochromic dye being present in a photochromic coat material forming a polymeric coat on the substrate, and (d) post-processing the substrate provided with a functional coloration on the second main face in step (c), in such a way that the tint on the firs
    Type: Application
    Filed: January 26, 2023
    Publication date: May 22, 2025
    Inventors: Herbert ZINNER, Simone HILBLE, Kurt FISCHER, Beate WIND, Hans-Peter SOMMER
  • Publication number: 20250161070
    Abstract: Methods of and instruments for positioning a sacroiliac joint implant in a dorsal trajectory down the joint. The methods may include positioning an integrated stylet and cannula adjacent the joint, removing the stylet from a cannula lumen, and advancing the implant through the cannula lumen with tamp and into the joint.
    Type: Application
    Filed: November 18, 2024
    Publication date: May 22, 2025
    Inventors: Paul M. SAND, Bret SCHNEIDER, Derek P. LINDSEY, Francois FOLLINI, Nikolas F. KERR, Roxanne SIMON, Scott A. YERBY
  • Publication number: 20250160727
    Abstract: A method for simultaneously detecting scattered light, deflected light, or a combination thereof from a target in a subject at a plurality of locations, the method including: placing a sensor head on the subject proximal the target, the sensor head including: a housing; an illumination output coupled to an illumination source; a plurality of light collection units each comprising one or more polished ends of one or more respective optical fibers, each light collection unit disposed at a respective predetermined radial distance from the illumination output; wherein a number of polished ends in each light collection unit corresponds to the respective predetermined radial distance; generating, with the illumination source, the light energy; collecting, with at least one of the light collection units, at least one of scattered light and/or refracted light to provide collected light; and passing at least a portion of the collected light through a spectrometer.
    Type: Application
    Filed: January 23, 2025
    Publication date: May 22, 2025
    Inventors: David Bannon, Domhnull Granquist-Fraser, Paul Bartel, Kevin Didona, Carson Roberts, Blair Simon
  • Publication number: 20250161576
    Abstract: An injection device with an elongated housing and integrated electronic circuitry allows a combination of mechanical play compensation and optical signal transmission through the housing by using translucent or transparent thermoplastic elastomer TPE to realize an elastic coupling in an opening of the housing.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Inventors: Simon Martin Bosshard, Christian Schrul, Dominik Zumstein
  • Publication number: 20250168318
    Abstract: A system for chromatic aberration and geometry calibration and validation of VR HMDs has a left eye display and a right eye display, comprises a measurement device with a left (11) and a right (12) camera.
    Type: Application
    Filed: February 21, 2023
    Publication date: May 22, 2025
    Applicant: LOFT DYNAMICS AG
    Inventors: Christian Marty, Hannes Diethelm, Simon Locher
  • Publication number: 20250165677
    Abstract: Devices, systems, and methods accelerated, variable load finite element analysis for vehicle design can provide a graphical representation of a finite element mesh and enter the graphical representation as an input to a recurrent neural network (RNN). Such solutions can develop a time series mesh (TSM) as an output from the RNN. Design of a component of the vehicle can be adapted based on the output.
    Type: Application
    Filed: November 16, 2023
    Publication date: May 22, 2025
    Inventors: Megan HARDY, Brett DUFFORD, Gianina Alina NEGOITA, Wesley TESKEY, Lars GREVE, Bram Pieter VAN DE WEG, Simon THEL
  • Publication number: 20250164398
    Abstract: A method for extending a depth of field of a nucleic acid sequencer may comprise optimization steps which are repeated one or more times, in which a result of passing light through an objective lens and a mask is compared with an ideal result, and any discrepancy is used to update the mask. Such a mask may be incorporated into a nucleic acid sequencer which adds fluorescent tags to nucleic acid sites and then detect light emitted from the fluorescent tags, thereby extending the sequencer's depth of field.
    Type: Application
    Filed: March 14, 2024
    Publication date: May 22, 2025
    Inventors: Jeffrey GAU, Joseph PINTO, Anindita DUTTA, Geraint EVANS, Yina WANG, Simon PRINCE, Stanley HONG
  • Publication number: 20250163811
    Abstract: An additively manufactured article comprises a superalloy composition and a microstructure. The microstructure comprises a gamma-prime phase greater than or equal to 35% by volume of the microstructure. The microstructure comprises grains having an average aspect ratio of greater than or equal to 5.
    Type: Application
    Filed: November 16, 2023
    Publication date: May 22, 2025
    Applicants: Arcam AB, Concept Laser GmbH
    Inventors: Markus Ramsperger, Simon Eichler
  • Publication number: 20250155435
    Abstract: Fusion polypeptides are disclosed which are substrates for Kutzneria albida transglutaminase. The fusion polypeptides comprise one or more FKBP chaperone(s) and a target polypeptide. Each of these elements is separated from the neighboring element by a linker amino acid sequence. It was found that inserting glutamic acid containing transglutaminase recognition motifs into the linker amino acid chains is advantageous. Subsequent labeling reactions catalyzed by the transglutaminase surprisingly provide labeled fusion polypeptides have superior properties when compared with chemically random-labeled fusion polypeptides of similar design. Assays and kits are provided for in vitro detection of target antibodies in samples.
    Type: Application
    Filed: November 9, 2023
    Publication date: May 15, 2025
    Inventors: Simon Jochum, Matthias Hemann, Juliane Benz
  • Publication number: 20250156673
    Abstract: A limit value detection device for multiple detection of a limit value event has a catch mechanism manufactured using microstructuring technology, having a first and a second catch element, each having a plurality of catches, a pawl configured to engage in a catch intermediate space between two adjacent catches of the first catch element, the first catch element being movable relative to the pawl in a freewheeling direction and movement thereof relative to the pawl in a blocking direction being blockable by the pawl, and an actuating device configured to move the first catch element and the pawl relative to each other in a catch-by-catch manner in the freewheeling direction. The first and second catch elements together form a counting unit in which the counter status for indicating the detected limit value events is determined based on the position of the two catch elements relative to each other.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 15, 2025
    Applicant: Hahn-Schickard-Gesellschaft für angewandte Forschung e.V.
    Inventors: Sven SPIETH, Simon HERRLICH, Daniel HOFFMANN
  • Publication number: 20250155853
    Abstract: A method is for providing a process parameter model for parameterizing one or more process steps of a production process for manufacturing a component includes providing a quality model for determining a quality. The quality model is configured to specify the quality of the resulting component directly or with the aid of a predefined quality function based on one or more predefined measurement variables and/or one or more predefined state variables, which each specify a property of a pre-product or intermediate product of the component being manufactured and/or a production device for performing a process step and/or at least one environmental condition, and based on one or more process parameters which control a corresponding one of the process steps. The method further includes training a data-based process parameter model to output one or more process parameters based on one or more measurement variables captured by a sensor.
    Type: Application
    Filed: January 23, 2023
    Publication date: May 15, 2025
    Inventors: Simon Baeuerle, Damir Shakirov, Andreas Steimer
  • Publication number: 20250160055
    Abstract: A display device comprising a variable-wavelength light emitting diode (LED) is provided. The variable-wavelength LED comprises: an n-doped portion, a p-doped portion, and a light emitting region located between the n-doped portion and the p-doped portion. The light emitting region comprises a light-emitting layer which emits light at a peak emission wavelength under electrical bias thereacross. The variable-wavelength LED is configured to receive a power supply, and the peak emission wavelength of the LED is continuously controllable over an emission wavelength range of at least 40 nm by varying the power supply.
    Type: Application
    Filed: July 28, 2022
    Publication date: May 15, 2025
    Inventors: Tongtong ZHU, Alex YUDIN, Simon HAMMERSLEY
  • Publication number: 20250151653
    Abstract: A pickup assembly of an agricultural harvester comprising a pickup assembly frame and tracking wheels. The tracking wheels are each supported for rotation by a tracking wheel support mechanism attached to the pickup assembly frame. The tracking wheel support mechanism comprises a support arm and a support member. A proximal end of the support arm is rotatably connected to the support member (320) about a support member axis parallel to the axis of rotation of the tracking wheel. The support arm is restrained against rotation relative to the support member by a frangible member which is configured to break when exposed to a predetermined load condition.
    Type: Application
    Filed: August 23, 2024
    Publication date: May 15, 2025
    Inventors: Jeffrey BLANCKE, Stijn VAN BELLEGHEM, Simon BEELAERT