Patents by Inventor Sivakumaran Meenakshisunderam

Sivakumaran Meenakshisunderam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical Dosage Form of an Antidepressant
    Publication number: 20110196032
    Abstract: The present invention relates to pharmaceutical dosage forms of an antidepressant. More particularly, the present invention relates to pharmaceutical dosage forms of Escitalopram oxalate. The present invention also relates to a process for the preparation of pharmaceutical dosage forms of Escitalopram oxalate.
    Type: Application
    Filed: May 18, 2006
    Publication date: August 11, 2011
    Inventors: Ashish Gogia, Krishna Murthy Vanasi, Sivakumaran Meenakshisunderam
  • Process for the preparation of donepezil hydrochloride
    Patent number: 7994328
    Abstract: The present invention relates to an improved process for the preparation of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride of Formula I.
    Type: Grant
    Filed: February 8, 2007
    Date of Patent: August 9, 2011
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Mahesh Nagarimadugu, Arun Kumar Gupta, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for the preparation of Escitalopram
    Patent number: 7939680
    Abstract: The present invention relates to an improved process for the preparation of Escitalopram of the Formula (I), which comprises, isolation of Diol compound as an oxalate salt, resolution of Diol compound and cyclization of resolved compound of Formula (VII). The present invention provides a process to obtain pure Diol compound by preparing its Oxalate salt, which is useful for resolution of enantiomers.
    Type: Grant
    Filed: July 20, 2006
    Date of Patent: May 10, 2011
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Vipin Kumar Kaushik, Umar Khan Mohammed, Sivakumaran Meenakshisunderam
  • Process for the preparation of angiotensin II antagonist
    Patent number: 7880015
    Abstract: The present invention provides a method for the preparation of N-(1-oxopentyl)-N-[[2?-(1H-tetra-zol-5-yl)[1,1?-biphenyl]-4-yl]methyl]-L-valine (Valsartan) which comprises; treating N-[[2?-(1-triphenylmethyl-tetra-zol-5-yl)biphenyl-4-yl]methyl]-L-valine methyl ester (X) with oxalic acid or its hydrates in a solvent to produce N-[[2?-(1-triph-enylmethyl-tetrazol-5-yl)biphenyl-4-yl]methy]-L-valine methyl ester oxalate (Xa) and treating the compound (Xa) with a base in a solvent followed by reacting with valeryl chloride in presence of base in a solvent to produce N-[[2?-(1-triphenylmethyl-tetra-zol-5-yl)[1,1?biphenyl]-4-yl]methyl]-N-valeryl-L-valine methyl ester (XI), de-protecting the compound (XI) using anhydrous acidic conditions to produce N-(1-oxopentyl)-N-[[2?-(1-H-tetrazol-5-yl)[1,1?biphenyl]-4-yl]methyl-L-valine methyl ester (V) followed by treating with base in a solvent to produce Valsartan.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: February 1, 2011
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sankar Reddy Budidet, Senthil Kumar Natarajan, Venkata Kishore Gowrabathina, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE PREPARATION OF SUBSTANTIALLY PURE (2S,3S,5S)-5-AMINO-2-N,N-DIBENZYLAMINO-3-HYDROXY-1,6-DIPHENYLHEXANE
    Publication number: 20100317855
    Abstract: The present invention relates to the purification of (2S,3S,5S)-5-amino-2-N,N-dibenzylamino-3-hydroxy-1,6-diphenylhexane (III) by making its crystalline acid addition salt, which can be used as such to produce Lopinavir/Ritonavir with high purity and yield.
    Type: Application
    Filed: June 5, 2008
    Publication date: December 16, 2010
    Inventors: V Raghava Reddy Ambati, Srinivas Garaga, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for Preparing Tamsulosin Hydrochloride
    Publication number: 20100267987
    Abstract: The invention relates to an process for preparing Tamsulosin hydrochloride of Formula (I) which comprises (i) reacting (R)-(?)-5-(2-amino-propyl)-2-methoxybenzenesulfonamide of Formula (II) with substituted phenoxy compound of Formula (III), wherein Z represents a removing group, such as —OSO2CH3, —OSO2C6H4CH3, —F, —Br, —Cl, or —I, in a solvent in the presence of an alkaline earth metal oxide to obtain Tamsulosin base and (ii) converting Tamsulosin base into hydrochloride salt in a solvent by addition of aqueous hydrochloric acid.
    Type: Application
    Filed: August 10, 2006
    Publication date: October 21, 2010
    Applicant: AUR OBINDO PHARMA LTD
    Inventors: Anand Gopalkrishna Kamat, Narsimha Penthala, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE PREPARATION OF LAMIVUDINE FORM I
    Publication number: 20100190982
    Abstract: The present invention provides a process for preparing a stable crystalline solid of Lamivudine polymorphic Form I, which does not change to Form II during storage and pharmaceutical unit operations.
    Type: Application
    Filed: September 1, 2008
    Publication date: July 29, 2010
    Inventors: Janardhana Rao Vascuri, Ravinder Reddy Vennapureddy, Shankar Rama, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARING PURINE DERIVATIVE
    Publication number: 20100137592
    Abstract: A process for the preparation of famciclovir a compound of Formula (I) and its intermediates.
    Type: Application
    Filed: June 2, 2008
    Publication date: June 3, 2010
    Inventors: Asif Parvez Sayyed, Murali Krishna Ankaraju, Ravinder Reddy Vennapureddy, Shankar Rama, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE PREPARATION OF ARIPIPRAZOLE
    Publication number: 20100130744
    Abstract: The present invention relates to an improved process for the preparation of 7-[4-[4-(2,3-dichlorophenyl)-1-piper-azinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone of Formula (I).
    Type: Application
    Filed: May 29, 2008
    Publication date: May 27, 2010
    Inventors: Mahesh Nagarimadugu, Vipin Kumar Kaushik, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARING AN OPTICALLY ACTIVE PROTON PUMP INHIBITOR
    Publication number: 20100125142
    Abstract: An improved process for the preparation of (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole of Formula I, (I) with high enantiomeric excess from racemic mixture.
    Type: Application
    Filed: May 30, 2008
    Publication date: May 20, 2010
    Inventors: Shankar Reddy Budidet, Brajesh Kumar Sinha, Somappa Somannavar Yallappa, Senthil Kumar Natarajan, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for preparing Nevirapine
    Publication number: 20100125137
    Abstract: An improved process for preparing 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2?,3?-e][1,4]diazepin-6-one of Formula (I).
    Type: Application
    Filed: May 14, 2008
    Publication date: May 20, 2010
    Inventors: Jagan mohan Reddy Sanapureddy, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Amorphous 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate salt
    Publication number: 20100076047
    Abstract: The present invention relates to a novel amorphous form of 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate (Carvedilol dihydrogen phosphate) of Formula (I), and a process for the preparation thereof.
    Type: Application
    Filed: August 20, 2008
    Publication date: March 25, 2010
    Inventors: Sankar Reddy Budidet, Yallappa Somappa Somannavar, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for the Preparation of Irbesartan
    Publication number: 20100056797
    Abstract: The present invention relates to an improved process for the preparation of 2-n-butyl-3-[[2?-(1H-tetrazol-5-yl)[1,1?-biphenyl]-4-yl]-1,3-diazaspiro[4.
    Type: Application
    Filed: April 23, 2007
    Publication date: March 4, 2010
    Inventors: Venkata vara prasada rao Korrapati, Venkata subramanyeswara rao Inti, Rani Ananta, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARING ROSUVASTATIN CALCIUM
    Publication number: 20100048899
    Abstract: The present invention relates to an improved process for preparing Rosuvastatin calcium of Formula I.
    Type: Application
    Filed: October 29, 2007
    Publication date: February 25, 2010
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Narayan K.A.S.S. Garimella, Sukumar Nandi, Sunil Kumar Buridipad, Gangadhar Bhima Shankar Nangi, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARING ROSUVASTATIN CALCIUM
    Publication number: 20100029940
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of Formula I which is an intermediate useful in the preparation of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methyl-sulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid] calcium salt of Formula II
    Type: Application
    Filed: December 11, 2007
    Publication date: February 4, 2010
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • Process for the Preparation of Leukotriene Receptor Antagonist (Montelukast Sodium)
    Publication number: 20090326232
    Abstract: The present invention relates to an improved process for the preparation of [R-(E)]-1-[[[1-[3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic acid, monosodium salt of Formula (I).
    Type: Application
    Filed: June 25, 2007
    Publication date: December 31, 2009
    Inventors: Uttam Kumar Ray, Sreenivasulu Boju, Sreenivasa Rao Pathuri, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARATION OF ROSUVASTATIN CALCIUM FIELD OF THE INVENTION
    Publication number: 20090312547
    Abstract: The present invention relates to an improved process for preparing (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium of Formula (I).
    Type: Application
    Filed: February 4, 2008
    Publication date: December 17, 2009
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • Process For the Preparation of Angiotensin II Antagonist
    Publication number: 20090281326
    Abstract: The present invention provides a method for the preparation of N-(1-oxopentyl)-N-[[2?-(1H-tetra-zol-5-yl)[1,1?-biphenyl]-4-yl]methyl]-L-valine (Valsartan) which comprises; treating N-[[2?-(1-triphenylmethyl-tetra-zol-5-yl)biphenyl-4-yl]methyl]-L-valine methyl ester (X) with oxalic acid or its hydrates in a solvent to produce N-[[2?-(1-triph-enylmethyl-tetrazol-5-yl)biphenyl-4-yl]methy]-L-valine methyl ester oxalate (Xa) and treating the compound (Xa) with a base in a solvent followed by reacting with valeryl chloride in presence of base in a solvent to produce N-[[2?-(1-triphenylmethyl-tetra-=zol-5-yl)[1,1?biphenyl]-4-yl]methyl]-N-valeryl-L-valine methyl ester (XI), de-protecting the compound (XI) using anhydrous acidic conditions to produce N-(1-oxopentyl)-N-[[2?-(1-H-tetrazol-5-yl)[1,1?biphenyl]-4-yl]methyl-L-valine methyl ester (V) followed by <treating with base in a solvent to produce Valsartan.
    Type: Application
    Filed: June 29, 2007
    Publication date: November 12, 2009
    Inventors: Sankar Reddy Budidet, Senthil Kumar Natarajan, Venkata Kishore Gowrabathina, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Aqueous oral solution of bisphosphonic acid
    Patent number: 7605148
    Abstract: The present invention relates to stable aqueous oral formulation of bisphosphonic acid or its pharmaceutically acceptable salts. More particularly, the present invention relates to stable aqueous oral formulation of alendronate sodium. The present invention also relates to a process for the preparation of stable aqueous oral formulation of alendronate sodium.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: October 20, 2009
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Ramesh Babu Batta, Umesh Nandkumar Khatavkar, Hidaytulla Shamshuddin Aga, Kishor Dattatray Deo, Sivakumaran Meenakshisunderam
  • Process for the preparation of Florfenicol
    Patent number: 7601869
    Abstract: The present invention relates to a method for the preparation of Florfenicol from Fluoroamine compound, namely (1R,2S)-1-[4-(methylsulfonyl)phenyl]-2-amino-3-fluoro-1-propanol (II), by reaction with dihaloacetic acid ester in an organic solvent in presence of an inorganic base.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: October 13, 2009
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Mallikarjuna Reddy Karuru, Arun Kumar Gupta, Sivakumaran Meenakshisunderam