Patents by Inventor Sivaram Pillarisetti

Sivaram Pillarisetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9782407
    Abstract: The present invention provides a method for treating or preventing a condition or disease in a human or an animal subject wherein the condition or disease is associated with lipoprotein metabolism, the method comprising administering to the subject a composition comprising benzylamine compounds.
    Type: Grant
    Filed: April 15, 2015
    Date of Patent: October 10, 2017
    Assignee: DR. REDDY'S LABORATORIES LTD.
    Inventors: Anima Baruah, Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti, Santanu Maitra, Christopher W. Alexander, Jennepalli Sreenu, Indu Dager, Shanavas Alikunju
  • Patent number: 9765030
    Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: September 19, 2017
    Assignee: DR. REDDY'S LABORATORIES LTD.
    Inventors: Anima Baruah, Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti, Santanu Maitra, Christopher W. Alexander, Jennepalli Sreenu, Indu Dager, Shanavas Alikunju
  • Publication number: 20150216866
    Abstract: The present invention provides a method for treating or preventing a condition or disease in a human or an animal subject wherein the condition or disease is associated with lipoprotein metabolism, the method comprising administering to the subject a composition comprising benzylamine compounds.
    Type: Application
    Filed: April 15, 2015
    Publication date: August 6, 2015
    Inventors: Anima BARUAH, Dibyendu DE, Ish Kumar KHANNA, Sivaram PILLARISETTI, Santanu MAITRA, Christopher W. ALEXANDER, Jennepalli SREENU, Indu DAGER, Shanavas ALIKUNJU
  • Patent number: 9040558
    Abstract: The invention is directed to novel substituted benzylamino quinolines, compounds comprising substituted benzylamino quinolines, methods of making substituted benzylamino quinolines, the use of substituted benzylamino quinolines for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism, and the use of substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors.
    Type: Grant
    Filed: December 28, 2005
    Date of Patent: May 26, 2015
    Assignee: DR. REDDY'S LABORATORIES LTD.
    Inventors: Anima Baruah, Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti, Santanu Maitra, Christopher W. Alexander, Jennepalli Sreenu, Indu Dager, Shanavas Alikunju
  • Publication number: 20140142178
    Abstract: Novel compounds of Formula I are provided: its stereoisomers and/or pharmaceutically acceptable salts for the treatment of diabetes and diabetes-associated dyslipidemia, wherein R1 is selected from a group consisting of hydroxy, alkoxy, amine, alkyl, haloalkyl, NHSO2R, or NHCOR wherein R is selected from alkyl or cycloalkyl, NHR? wherein R? is alkyl or cycloalkyl optionally substituted by hydroxy or alkoxy; and n1 and n2 are independently selected from 0, 1, and 2. At least one of R3 and R4 and/or R5 and R6 form a cyclic ring of 3-8 carbon atoms optionally containing alkyl groups, hetero atoms, or functional groups such as O, N, SO2. Additionally, when R3 and R4 or R5 and R6 do not form a cyclic ring, then they may be independently selected from hydrogen, alkyl, branched alkyl, and cycloalkyl. L1 is a linear aliphatic chain optionally containing from 4 to 16 carbon atoms. The chain may optionally be substituted one or more times by alkyl, branched alkyl, cycloalkyl, or aryl.
    Type: Application
    Filed: January 6, 2014
    Publication date: May 22, 2014
    Applicant: Kareus Therapeutics, SA
    Inventors: Ish Khanna, Sivaram Pillarisetti
  • Publication number: 20140134235
    Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
    Type: Application
    Filed: October 14, 2013
    Publication date: May 15, 2014
    Applicant: DR. REDDY'S LABORATORIES LTD.
    Inventors: Anima BARUAH, Dibyendu DE, Ish Kumar KHANNA, Sivaram PILLARISETTI, Santanu MAITRA, Christopher W. ALEXANDER, Jennepalli SREENU, Indu Dagar, Shanavas Alikunju
  • Publication number: 20140121267
    Abstract: Novel compounds of Formula A1 are provided: its stereoisomers and/or pharmaceutically acceptable salts for the treatment of diabetes and diabetes-associated dyslipidemia, wherein R7 is independently selected from a group consisting of hydroxy, alkoxy, alkyl, amine, NHR? wherein R? is alkyl or cycloalkyl optionally substituted by hydroxy or alkoxy, NHSO2R or NHCOR, wherein R is selected from alkyl or cycloalkyl. At least one of R3 and R4 and/or R5 and R6 form a cyclic ring of 3-8 carbon atoms optionally containing alkyl groups, hetero atoms, or functional groups such as O, N, SO2. Additionally R3 and R4 or R5 and R6, when they do not form a cyclic ring, are independently selected from hydrogen, alkyl, branched alkyl, and cycloalkyl. L1 is independently a linear aliphatic chain optionally containing from 6 to 16 carbon-atoms and L1 may optionally be substituted one or more times by alkyl, branched alkyl, cycloalkyl, or aryl.
    Type: Application
    Filed: January 6, 2014
    Publication date: May 1, 2014
    Applicant: Kareus Therapeutics, SA
    Inventors: Ish Khanna, Sivaram Pillarisetti
  • Patent number: 8623897
    Abstract: The invention is directed to novel compounds of Formula I: as well as its stereoisomers and/or pharmaceutically acceptable salts, for the treatment of diabetes and diabetes associated dyslipidemia.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: January 7, 2014
    Assignee: Kareus Therapeutics, SA
    Inventors: Ish Khanna, Sivaram Pillarisetti
  • Patent number: 8604055
    Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: December 10, 2013
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Anima Baruah, Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti, Santanu Maitra, Christopher W. Alexander, Jennepalli Sreenu, Indu Dagar, Shanavas Alikunju
  • Publication number: 20120071528
    Abstract: The invention is directed to novel compounds of Formula I: as well as its stereoisomers and/or pharmaceutically acceptable salts, for the treatment of diabetes and diabetes associated dyslipidemia.
    Type: Application
    Filed: September 20, 2011
    Publication date: March 22, 2012
    Applicant: KAREUS THERAPEUTICS, SA
    Inventors: Ish Khanna, Sivaram Pillarisetti
  • Publication number: 20120064161
    Abstract: Pharmaceutical formulations comprising niacin in a matrix comprising a hydrophobic polymer that modifies release of niacin.
    Type: Application
    Filed: November 18, 2011
    Publication date: March 15, 2012
    Applicants: DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
    Inventors: Rajesh Vooturi, Dhananjay Singare, Shantanu Yeshwant Damle, Pradeep Jairao Karatgi, Sesha Sai Marella, Harshal Prabhakar Bhagwatwar, Ish Kumar Khanna, Raviraj Sukumar Pillai, Sivaram Pillarisetti
  • Patent number: 8008328
    Abstract: Methods for the treatment of insulin resistance, diabetes, and/or diabetes associated dyslipidemia by administering niacin and meloxicam are disclosed.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: August 30, 2011
    Assignee: Reddy US Therapeutics, Inc.
    Inventors: Uday Saxena, Sivaram Pillarisetti, Ish Khanna
  • Patent number: 7989463
    Abstract: Novel bicyclic compounds of the formula (I), stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided. Additionally, methods of forming novel bicyclic compounds, stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided: wherein R1, R2, m, and n are defined herein.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: August 2, 2011
    Assignee: Dr. Reddy's Laboratories Limited
    Inventors: Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti
  • Patent number: 7820654
    Abstract: The present invention is directed to a compounds, methods and compositions for making the compounds and methods of treating a variety of diseases and disease states including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan, comprising the administration of new heterocyclic compounds, particularly substituted pyrimidines.
    Type: Grant
    Filed: September 23, 2005
    Date of Patent: October 26, 2010
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Manojit Pal, Srinivas Kalleda, Srinivas Padakanti, Nalivela Kumara Swamy, Koteswar Rao Yeleswarapu, Christopher W. Alexander, Ish Khanna, Javed Iqbal, Sivaram Pillarisetti, Deepak Barange
  • Publication number: 20100144731
    Abstract: Novel bicyclic compounds, stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided. Additionally, methods of forming novel bicyclic compounds, stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided.
    Type: Application
    Filed: September 3, 2009
    Publication date: June 10, 2010
    Applicant: Dr. Reddy's Laboratories Ltd.
    Inventors: Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti
  • Publication number: 20100144722
    Abstract: Novel heterocyclic compounds, sstereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided. Additionally, methods of forming novel heterocyclic compounds, stereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided.
    Type: Application
    Filed: September 3, 2009
    Publication date: June 10, 2010
    Applicant: Dr. Reddy's Laboratories Ltd.
    Inventors: Christopher W. Alexander, Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti
  • Patent number: 7700774
    Abstract: The present invention provides, among other things, new bicyclic heterocyclic compounds, compositions comprising these heterocyclic compounds, methods of making the heterocyclic compounds, and methods of using these heterocyclic compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: April 20, 2010
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Anima Baruah, Ish Khanna, Sivaram Pillarisetti
  • Publication number: 20080275049
    Abstract: A novel method of identifying compounds capable of upregulating GATA activity is disclosed. The method includes providing a sample of cells that express GATA, providing a sample of a candidate compound, contacting the cell sample and the compound sample, and measuring a quantitative indicator of GATA activity within the cell sample after the contacting step. GATA inducers identified by the method and uses therefore to upregulate GATA activity in subjects and to prevent or treat atherosclerosis or diabetes in subjects are also described.
    Type: Application
    Filed: May 1, 2008
    Publication date: November 6, 2008
    Applicant: REDDY US THERAPEUTICS, INC.
    Inventors: John Anastasios Polikandriotis, Sivaram Pillarisetti, Ish Khanna, Uday Saxena
  • Publication number: 20080214531
    Abstract: Methods for the treatment of insulin resistance, diabetes, and/or diabetes associated dyslipidemia by administering niacin and meloxicam are disclosed.
    Type: Application
    Filed: December 28, 2007
    Publication date: September 4, 2008
    Applicant: Reddy US Therapeutics, Inc.
    Inventors: Uday Saxena, Sivaram Pillarisetti, Ish Khanna
  • Publication number: 20080119571
    Abstract: The present invention shows that pharmacological up regulation of SRB-1, ABC-A1 and LCAT genes collectively can be used to promote reverse cholesterol transport and increase circulating HDL cholesterol as treatment for atherosclerosis and related cardiovascular disorders.
    Type: Application
    Filed: June 7, 2007
    Publication date: May 22, 2008
    Applicant: REDDY US THERAPEUTICS, INC.
    Inventors: Ish Khanna, Sivaram Pillarisetti, Uday Saxena