Patents by Inventor Sivaram Pillarisetti

Sivaram Pillarisetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions of novel triazine compounds
    Publication number: 20070099874
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: March 26, 2003
    Publication date: May 3, 2007
    Applicant: Reddy US Therapeutics, Inc.
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
  • Methods and compositions of novel triazine compounds
    Publication number: 20070043051
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: October 5, 2006
    Publication date: February 22, 2007
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Karen Campbell
  • Methods and compositions of novel triazine compounds
    Patent number: 7173032
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: February 6, 2007
    Assignee: Reddy US Therapeutics, Inc.
    Inventors: Richard T. Timmer, Christopher W. Alexander, Sivaram Pillarisetti, Uday Saxena, Karen A. Campbell
  • Methods and compositions of novel triazine compounds
    Patent number: 7169785
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: January 30, 2007
    Assignee: Reddy US Therapeutics, Inc.
    Inventors: Richard T. Timmer, Christopher W. Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Rao Yeleswarapu, Manojit Pal, Jangalgar Tirupathy Reddy, Velagala Venkata Rama Murali Krishma Reddy, Sesha Sridevi Alluri, Potlapally Rajender Kumar, Gaddam Om Reddy
  • Medical devices employing triazine compounds and compositions thereof
    Patent number: 7169784
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: January 30, 2007
    Assignee: Reddy US Therapeutics, Inc.
    Inventors: Richard T. Timmer, Christopher W. Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Rao Yeleswarapu, Manojit Pal, Jangalger Tirupathy Reddy, Velagala Venkata Rama Murali Krishna Reddy, Bhatlapenumarthy Sesha Sridevi Alluri, Potlapally Rajender Kumar, Gaddam Om Reddy
  • Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors
    Publication number: 20070015758
    Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
    Type: Application
    Filed: June 28, 2006
    Publication date: January 18, 2007
    Inventors: Anima Baruah, Dibyendu De, Ish Khanna, Sivaram Pillarisetti, Santanu Maitra, Christopher Alexander, Jennepalli Sreenu, Indu Dager
  • Methods and compositions of novel triazine compounds
    Patent number: 7163943
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: January 16, 2007
    Assignee: Reddy US Therapeutics, Inc.
    Inventors: Richard T. Timmer, Christopher W. Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Rao Yeleswarapu, Manojit Pal, Jangalgar Tirupathy Reddy, Velagala Venkata Rama Murali Krishna Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Rajender Kumar, Gaddam Om Reddy
  • Methods and compositions of novel triazine compounds
    Publication number: 20070004729
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: June 20, 2006
    Publication date: January 4, 2007
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
  • Methods and compositions of novel triazine compounds
    Publication number: 20060258641
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: May 25, 2006
    Publication date: November 16, 2006
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
  • Methods and compositions of novel triazine compounds
    Patent number: 7132423
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: November 7, 2006
    Assignee: Reddy US Therapeutics, Inc.
    Inventors: Richard T. Timmer, Christopher W. Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Rao Yeleswarapu, Manojit Pal, Jangalgar Tirupathy Reddy, Velagala Venkata Rama Murali Krishna Reddy, Sesha Sridevi Alluri, Potlapally Rajender Kumar, Gaddam Om Reddy
  • Methods and compositions of novel triazine compounds
    Patent number: 7112587
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: September 26, 2006
    Assignee: Reddy US Therapeutics, Inc.
    Inventors: Richard T. Timmer, Christopher W. Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Rao Yeleswarapu, Manojit Pal, Jangalgar Tirupathy Reddy, Velagala Venkata Rama Murali Krishna Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Rajendar Kumar, Gaddam Om Reddy
  • Novel benzylamine derivatives as CETP inhibitors
    Publication number: 20060178514
    Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
    Type: Application
    Filed: December 28, 2005
    Publication date: August 10, 2006
    Inventors: Anima Baruah, Dibyendu De, Ish Khanna, Sivaram Pillarisetti, Santanu Maitra, Christopher Alexander, Jennepalli Sreenu
  • Methods and compositions of novel triazine compounds
    Publication number: 20060172984
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: November 22, 2005
    Publication date: August 3, 2006
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Yeleswarapu Rao, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
  • Novel heterocyclic compounds and their pharmaceutical compositions
    Publication number: 20060135551
    Abstract: The present invention provides, among other things, new bicyclic heterocyclic compounds, compositions comprising these heterocyclic compounds, methods of making the heterocyclic compounds, and methods of using these heterocyclic compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
    Type: Application
    Filed: December 20, 2005
    Publication date: June 22, 2006
    Inventors: Anima Baruah, Ish Khanna, Sivaram Pillarisetti
  • Heterocyclic and bicyclic compounds, compositions and methods
    Publication number: 20060128702
    Abstract: The present invention provides, among other things, new bicyclo heterocyclic compounds, compositions comprising these heterocyclic compounds, methods of making the heterocyclic compounds, and methods of using these heterocyclic compounds for treating a variety of conditions and disease states associated with, for example, cellular proliferation, inflammation, glycosidase expression, or the low expression of Perlecan.
    Type: Application
    Filed: November 23, 2005
    Publication date: June 15, 2006
    Inventors: Manojit Pal, Ish Khanna, Venkataraman Subramanian, Srinivas Padakanti, Sivaram Pillarisetti
  • Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them
    Publication number: 20060128729
    Abstract: The present invention provides, among other things, new bicyclo heterocyclic compounds, compositions comprising these heterocyclic compounds, methods of making the heterocyclic compounds, and methods of using these heterocyclic compounds for treating a variety of conditions and disease states associated with, for example, cellular proliferation, inflammation, glycosidase expression, or the low expression of Perlecan.
    Type: Application
    Filed: November 23, 2005
    Publication date: June 15, 2006
    Inventors: Manojit Pal, Yeleswarapu Rao, Ish Khanna, Nalivela Swamy, Venkataraman Subramanian, Venkateswara Batchu, Javed Iqbal, Sivaram Pillarisetti
  • Novel pyrimidine compounds, process for their preparation and compositions containing them
    Publication number: 20060084645
    Abstract: The present invention provides new heterocyclic compounds, particularly substituted pyrimidines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.
    Type: Application
    Filed: September 23, 2005
    Publication date: April 20, 2006
    Inventors: Manojit Pal, Srinivas Kalleda, Srinivas Padakanti, Nalivela Swamy, Koteswar Yeleswarapu, Christopher Alexander, Ish Khanna, Javed Iqbal, Sivaram Pillarisetti, Deepak Barange
  • Triazine compounds and their analogs, compositions, and methods
    Publication number: 20050227983
    Abstract: The present invention relates to triazine compounds and their analogs and derivatives, and methods and compositions comprising these compounds. The compounds and compositions of this invention are useful for, among other things, treating pathophysiological conditions arising from inflammatory responses, inhibiting or blocking glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells, inhibiting smooth muscle proliferation, treating vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis, and the like.
    Type: Application
    Filed: March 24, 2004
    Publication date: October 13, 2005
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Sesha Alluri, Velagala Venkata Krishna Reddy, Manojit Pal, Jangalgar Reddy, Koteswar Yeleswarapu, Gaddam Reddy, Potlapally Kumar
  • Medical devices employing triazine compounds and compositions thereof
    Publication number: 20050137196
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: September 27, 2004
    Publication date: June 23, 2005
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Krishna Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Kumar, Gaddam Reddy
  • Medical devices employing triazine compounds and compositions thereof
    Publication number: 20050124619
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: September 27, 2004
    Publication date: June 9, 2005
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Krisha Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Kumar, Gaddam Reddy