Abstract: The invention provides a bidirectional converter that operates under an AC generation mode or a charge mode. The bidirectional converter may be a single component or circuit, which may include a DC-DC conversion stage using a unique “Smith 2 Stage conversion” technique and a DC-AC conversion stage or AC-DC conversion stage using a switchable filter depending on the mode. During the charge mode, the converter may be able to control the voltage and current of the DC output using a software algorithm, to match the battery being charged, or the DC receiver. This may enable the converter to control the nature of the DC output so it can be adapted to any energy storage technology. The controllable output voltage and synchronizable frequency may allow the converter to be used in series combinations to achieve a variety of high voltage outputs from simpler building blocks.

Abstract: The present concrete crack repair device (CCRD) can be comprised of two nodules connected by an elongated strip wherein the elongated strip can be narrower than the nodules in at least one plane. Both the elongated strip and the nodules can comprise carbon fibers wherein most of the carbon fibers are located within the same plane maximizing the tensile strength of the device. Installation of the CCRD can be performed by drilling holes into the surface of the concrete on either side of the crack and cutting a slot in the surface of the concrete between the two holes, or adding the holes after the slot has been cut, wherein the slot and holes are located in a line that is roughly perpendicular to the crack. The CCRD can then be installed by placing each nodule in a hole and the elongated strip within the slot.

Abstract: Disclosed are compositions, devices, systems, kits, and methods for neural ablation.

Abstract: Methods of treating individuals with autoimmune conditions characterized by elevated IL-6 levels comprising the administration of anti-IL-6 antibodies or antibody fragments are provided.

Abstract: Disclosed herein are recombinant meganucleases engineered to recognize and cleave a recognition sequence present in the human T cell receptor alpha constant region gene. The present disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells.

Abstract: A cabinet and a kit for retrofitting a cabinet are disclosed. The cabinet includes a stationary box, at least one moveable wing attached to the stationary box and configured to open and close relative to the stationary box. The at least one moveable wing includes at least one of a door hinged to the stationary box or a drawer mounted via slide actuators to the stationary box. The cabinet also includes a reed switch attached to the stationary box, a magnet attached to the at least one moveable wing, and at least one light emitting diode (LED) fixture installed within the stationary box. Opening the at least one wing separates the reed switch from the magnet and permits current to flow to the at least one LED fixture to illuminate at least an interior portion of the stationary box.

Abstract: A packaging device for a trocar assembly includes a trocar packaging clip having at least two holding structures configured to be detachably secured to the proximal portions of the trocar obturator and the cannula for retention of the trocar obturator and cannula relative to each other.

Abstract: Provided herein are compositions, methods, kits and systems for treating cells, tissues and subjects to alter age-related biology (e.g., to study or to treat age-related diseases and conditions). In particular, provided herein are compositions, methods, and uses for inhibition or modification of sialic acid or its cognate receptor to restore phagocytosis in aged cells.

Abstract: A defibrillation device for administering an electrotherapy, such as a dual-sequential defibrillation (DSD) electrotherapy. The defibrillation device can include a defibrillation therapy module, a physiological parameter module and a control module. The defibrillation therapy module can output one or more energies and the physiological parameter module can receive one or more physiological parameters, including electrocardiogram (ECG) data. The control module can analyze the physiological parameters to determine an indication for the administration of an electrotherapy and can determine a DSD electrotherapy. The DSD electrotherapy can be based at least in part on the physiological parameters, the indication for the administration of an electrotherapy or a review of the ECG data.

Abstract: A locking fastener may include a head and a shaft with a pin interface configured to engage a pin for locking the locking fastener in place. Such locking fasteners may be used to connect a plurality of casket components, and are especially useful for wooden caskets. Methods of making such locking fasteners using a fastener finishing device are also described herein.

Abstract: A method of advancing a guidewire having an imaging device disposed thereon within a cavity of a body includes placing a guidewire into a cavity of a body, said guidewire having an image sensor disposed about a guide member on a distal end of the guidewire and a plurality of power lines operatively coupled to the guide member and the image sensor. At least two power lines of the plurality of power lines are disposed on opposing sides of the guide member and extend from the distal end of the guidewire to a proximal end of the guidewire. As the guidewire is advanced through the body cavity, the distal end of the guidewire is positioned by pulling one of the at least two power lines while maintaining the position of the other of the at least two power lines.

Abstract: A trucker tray is provided. The trucker tray has a planar tray portion and a perpendicularly joined leg portion. The leg portion provides a lower cutout for snugly engaging an armrest so that a driver of a vehicle can hold their food on the tray portion.

Abstract: Systems and methods for an improved Internet search engine are provided. According to one embodiment, a search request is received from an end user via a browser based interface. The search request includes (i) initial constraint(s) to be used by the Internet search engine to constrain a search of real-time Internet content and (ii) user-specified search terms. A structured search query is generated based on company records of a company database matching the initial constraint(s). The search of real-time Internet content is performed and search results are returned by, for each web site domain specified in the structured search query, applying the search term(s) to a predetermined number of web pages for the domain. The search results, including a list of companies associated with the search results, is locally stored and presented to the end user. Interactive filtering and/or ranking of the locally stored search results is then facilitated.

Abstract: A method for authenticating a transaction includes: receiving, by a transaction processing unit of a computing system, a request for a transaction on a user account; generating, by the transaction processing unit, a personal identification number (PIN) and/or alert message; transmitting the PIN to a mobile device associated with the user account after a person requesting the transaction refuses authentication by a PIN-to-device process; and canceling, by the transaction processing unit, the transaction when a response to the PIN and/or alert message is received from the mobile device within a specified period of time.

Abstract: Apparatus include a plurality of electrode arrangements spaced apart from each other opposite an ion propagation axis and defining an ion transfer channel that extends along the ion propagation axis that tapers between an input end that is situated to receive ions and an output end that is situated to couple the received ions to an input end of an ion guide. Methods include positioning a plurality of electrode arrangements at oblique angles opposite an ion propagation axis so as to form a ion transfer channel that tapers between an input end and an output end, and coupling the output end of the ion transfer channel to an input end of an ion optical element so as to direct ions in the ion transfer channel into the ion optical element. Related systems are also disclosed.

Abstract: The present disclosure pertains to a system configured to prepare and use prediction models for classifying images. Some embodiments may: obtain, via a system return temperature sensor, a system return temperature; obtain, via an appliance return temperature sensor, an appliance return temperature; and responsive to a determination that the appliance return temperature is greater than the system return temperature by at least a first threshold amount, decrease, via a hardware processor, a speed of the appliance pump.

Abstract: Welding power supplies having adjustable current ramping rates are disclosed. An example welding power supply, comprising: a switched mode power supply to convert primary power to welding-type power having an output current based on a current control loop; a voltage sensing circuit to measure a weld voltage; a voltage comparator to determine whether the weld voltage corresponds to a welding arc condition or a short circuit condition; and a control circuit to: select a current ramping rate; and execute the current control loop to control the output current, the control circuit configured to, while the weld voltage corresponds to the short circuit condition, increase the output current at the current ramping rate.

Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body.

Abstract: Storage-based slow drain detecting and automated resolution is provided herein. A data storage system as described herein can include a memory that stores computer executable components and a processor that executes computer executable components stored in the memory. The computer executable components can include a switch query component that obtains a host transfer rate negotiated between a host device and a network switch from a host-connected port of the network switch; a comparison component that compares the host transfer rate to an array transfer rate negotiated between the network switch and a storage array; and a rate limiter component that limits a data transfer from the storage array to the host device to the host transfer rate in response to the host transfer rate being less than the array transfer rate.