Patents by Inventor Snahel Patel

Snahel Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BICYCLIC AMIDE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20220339129
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, R2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: January 4, 2021
    Publication date: October 27, 2022
    Applicant: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen
  • BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20210340151
    Abstract: Some embodiments of the invention provide compounds having the general formula I: wherein R1, R2, R3a and R3b are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Application
    Filed: July 8, 2021
    Publication date: November 4, 2021
    Applicant: Genentech, Inc.
    Inventors: Snahel PATEL, Gregory HAMILTON, Guiling ZHAO, Huifen CHEN, Blake DANIELS, Craig STIVALA
  • Biheteroaryl compounds and uses thereof
    Patent number: 11129832
    Abstract: The present invention provides for compounds of Formula I-I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases). R1, R2, R3, X1, X2, A and Cy variable in Formula I-I all have the meaning as defined herein.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: September 28, 2021
    Assignee: Genentech, Inc.
    Inventors: Anthony Estrada, Liting Dong, Kevin X. Chen, Paul Gibbons, Malcolm Huestis, Terry Kellar, Wen Liu, Changyou Ma, Joseph P. Lyssikatos, Alan G. Olivero, Snahel Patel, Daniel Shore, Michael Siu
  • Bicyclic ketone compounds and methods of use thereof
    Patent number: 11098058
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: August 24, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen, Blake Daniels, Craig Stivala
  • Bicyclic sulfones and sulfoxides and methods of use thereof
    Patent number: 11072617
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, RB1, RB2, n, p, q, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: July 27, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Craig Stivala, Huifen Chen, Blake Daniels
  • Inhibitors of RIP1 kinase and methods of use thereof
    Patent number: 11072607
    Abstract: The invention provides novel compounds having RIP1 kinase inhibitory activity, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: July 27, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton
  • Bicyclic amide compounds and methods of use thereof
    Patent number: 11071721
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, R2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: July 27, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen
  • AMIDO SPIROCYCLIC AMIDE AND SULFONAMIDE DERIVATIVES
    Publication number: 20210171545
    Abstract: Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.
    Type: Application
    Filed: July 31, 2020
    Publication date: June 10, 2021
    Inventors: Kenneth W. Bair, Timm R. Baumeister, Peter Dragovich, Xiongcai Liu, Snahel Patel, Po-Wai Yuen, Mark Zak, Guiling Zhao, Yamin Zhang, Xiaozhang Zheng
  • BICYCLIC PYRIDONE LACTAMS AND METHODS OF USE THEREOF
    Publication number: 20210163475
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, X, Z1 to Z5, L, n, the A ring, and the B ring, are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: February 4, 2021
    Publication date: June 3, 2021
    Applicant: Genentech, Inc.
    Inventor: Snahel PATEL
  • BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20210139504
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Application
    Filed: January 12, 2021
    Publication date: May 13, 2021
    Applicant: Genentech, Inc.
    Inventors: Snahel PATEL, Gregory HAMILTON, Guiling ZHAO, Huifen CHEN, Blake DANIELS, Craig STIVALA
  • Bicyclic lactams and methods of use thereof
    Patent number: 10988459
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, X, Z1, L, n, the A ring, the B ring, and the C ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: April 27, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Craig Stivala, Huifen Chen, Guiling Zhao
  • Bicyclic ketone compounds and methods of use thereof
    Patent number: 10975095
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: April 13, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen, Blake Daniels, Craig Stivala
  • Bicyclic pyridone lactams and methods of use thereof
    Patent number: 10947226
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, X, Z1 to Z5, L, n, the A ring, and the B ring, are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: March 16, 2021
    Assignee: Genentech, Inc.
    Inventor: Snahel Patel
  • Bicyclic amide compounds and methods of use thereof
    Patent number: 10933036
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, R2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: March 2, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen
  • PYRIDINE LACTAM COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20210032271
    Abstract: The invention provides compounds having the general formula I: or pharmaceutically acceptable salts thereof, wherein X, Y, R1, R2, R7a, R7b, X, RB1, RB2, n, p, q, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of use thereof.
    Type: Application
    Filed: October 9, 2020
    Publication date: February 4, 2021
    Applicant: Genentech, Inc.
    Inventor: Snahel Patel
  • BICYCLIC COMPOUNDS FOR USE AS RIP1 KINASE INHIBITORS
    Publication number: 20200283446
    Abstract: The invention provides novel compounds having the general formula I: or pharmaceutically acceptable salts thereof, wherein RA, RB1, RB2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Application
    Filed: April 9, 2020
    Publication date: September 10, 2020
    Applicant: Genentech, Inc.
    Inventors: Huifen CHEN, Gregory HAMILTON, Snahel PATEL, Guiling ZHAO, Blake DANIELS, Craig STIVALA
  • Amido spirocyclic amide and sulfonamide derivatives
    Patent number: 10730889
    Abstract: Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: August 4, 2020
    Assignees: FORMA TM, LLC, Genentech, Inc.
    Inventors: Kenneth W. Bair, Timm R. Baumeister, Peter Dragovich, Xiongcai Liu, Snahel Patel, Po-Wai Yuen, Mark Zak, Guiling Zhao, Yamin Zhang, Xiaozhang Zheng
  • BIHETEROARYL COMPOUNDS AND USES THEREOF
    Publication number: 20200188397
    Abstract: The present invention provides for compounds of Formula I-I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases). R1, R2, R3, X1, X2, A and Cy variable in Formula I-I all have the meaning as defined herein.
    Type: Application
    Filed: October 28, 2019
    Publication date: June 18, 2020
    Applicant: Genentech, Inc.
    Inventors: Anthony Estrada, Liting Dong, Kevin X. Chen, Paul Gibbons, Malcolm Huestis, Terry Kellar, Wen Liu, Changyou Ma, Joseph Lyssikatos, Alan Olivero, Snahel Patel, Daniel Shore, Michael Siu
  • BIHETEROARYL COMPOUNDS AND USES THEREOF
    Publication number: 20200171029
    Abstract: The present invention provides for compounds of Formula I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases). R1, R2, R3, X1, X2, A and Cy variable in Formula all have the meaning as defined herein.
    Type: Application
    Filed: September 11, 2019
    Publication date: June 4, 2020
    Applicant: Genentech, Inc.
    Inventors: Anthony ESTRADA, Alan G. OLIVERO, Snahel PATEL, Michael SIU, Joseph LYSSIKATOS
  • Biheteroaryl compounds and uses thereof
    Patent number: RE47848
    Abstract: The present invention provides for compounds of Formula I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases). R1, R2, R3, X1, X2, A and Cy variable in Formula all have the meaning as defined herein.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: February 11, 2020
    Assignee: Genentech, Inc.
    Inventors: Anthony Estrada, Alan G. Olivero, Snahel Patel, Michael Siu, Joseph Lyssikatos, Malcolm Huestis, Terry Kellar