Abstract: The present invention discloses a wheel machining technology in which blank quantity is furthest removed by using a 90-degree external turning tool. Under the premise that the rotation direction of a wheel is unchanged, an upper trench of a groove is processed by using a left-handed special cutting-off cutter. Under the premise that the rotation direction of the wheel is unchanged, a lower trench of the groove is processed by using a right-handed special cutting-off cutter. The left-handed special cutter and the right-handed special cutter are added to the wheel machining technology disclosed by the present invention, so as to complete the processing of a groove of an outer wheel rim; a processing program can be pre-edited, so that processed effects conform to the design requirements of drawings of products.

Abstract: The subject matter described herein relates to application installation/uninstallation across multiple systems. Responsive to installation or uninstallation of an application on a first system running on a device, it is determined whether the application is to be installed or uninstalled on a second system. Responsive to determining that the application is to be installed or uninstalled on the second system, an indication is set while the first system is running, where the indication causes installation or uninstallation of the application on the second system.

Abstract: A back plate, a method for manufacturing the back plate and a backlight module are provided. The method for manufacturing the back plate includes the following steps. A main body is provided. The main body includes a bottom portion and at least one sidewall connected to the bottom portion. The sidewall has a plurality of grooves, and each of the grooves has a first side surface and a second side surface. A first recess and a second recess corresponding to the first recess are respectively disposed on the first side surface and the second side surface. An external force is applied on the bottom portion to form each of the bottom portion and the sidewalls into arc shape, in which the first side surface contacts the second side surface of each groove, and a hole portion is formed between the first recess and the second recess.

Abstract: A derivative of homoserine lactone represented by formula I, and a preparation method and use thereof. The compound has a bacterial quorum-sensing regulatory effect, and can be used for prevention and/or treatment of a disease caused by a bacterial infection.

Abstract: Provided are a compound of formula I which can be used as a drug against small RNA virus infections, and optical isomers, pharmaceutically acceptable salts, solvates or hydrates thereof. Also provided are the preparation method of the compound, the method for using the compound for treating bacterial infections and the use of the compound in the preparation of a drug for preventing and/or treating viral diseases caused by small RNA viruses.

Abstract: Disclosed are an apparatus and method for controlling a laser projector to operate. The method includes: obtaining a plurality of operating parameters of the laser projector in operation; comparing each of obtained operating parameters with a preset parameter, and judging whether the laser projector fails, wherein the preset parameters are parameters of the laser projector which is operating normally; and determining failure information of the laser projector according to a result of a comparison if it is judged that the failure occurs.

Abstract: Systems and methods of security enhancement in a security panel are provided. Some systems can include a security system and a keyfob. The security system can identifies the keyfob, receive user input identifying a valid user pass code, and transmit the valid user pass code to the keyfob. The keyfob can save the received valid user pass code, receive user input identifying a first user input mechanism, receive user input identifying a sequence of user input mechanisms, determine whether the received sequence of user input mechanisms corresponds to the saved valid user pass code, and responsive to a valid correspondence, transmit a signal to the security system with instructions to execute an action associated with the first user input mechanism.

Abstract: The present invention provides fusion peptides, compositions, methods and kits for treating, reducing the risk of, lessening the severity of, preventing, or delaying the onset of amyloid-related disorders, such as Alzheimer's disease and HIV associated neurocognitive impairment.

Abstract: A network search method is provided. The network search method includes: keeping a terminal residing in a second network when the terminal is disconnected from a first network or has not registered to the first network; and performing a search operation for the first network by the terminal, when a serving cell and/or an adjacent cell corresponding to the terminal in the second network change. A network search device and a terminal are also provided. By utilizing the network search method, the network search device and the terminal, according to location change of the terminal, not only the network search frequency or search times for the first network can be reduced, to avoid a blind network search which may result in wasting power consumption of the terminal, but also the terminal can be connected to a specific network as soon as possible, and user experience is improved.

Abstract: A window blind assembly is disclosed and comprises a blind set, a light modulation device, a pull cord take-up device, and a coil spring control device. The blind set includes a bottom rail, a stopper, leaves, a blind ladder, pull cords, and a headrail. The light modulation device includes a wheel set, a wheel, a cover, an iron bar, a block, and a stick. The pull cord take-up device includes two mounts, a wrapping reel, and iron cores. The coil spring control device includes a bottom plate, a driving gear, a spring shaft, a coil spring, an upper gear cap, an upper cap, and a driven gear. The angle adjustment of the leaves of the blind set is realized by rotating the wrapping reel. When the bottom rail is pulled downwardly, the pull cords are driving the wrapping reel to rotate. The pull cord arranged on the coil spring control device is pulled out and wrapped around the wrapping reel.

Abstract: A locking device for window blind between two panes of glass is disclosed. The window blind is arranged between tow panes of glass through the attraction of the inside magnet and the outside magnet to transmit power to control the operation of the window blind. The locking device may achieve the effects of controlling smoothly and stopping firmly. The locking device may comprise a control shaft and a track. The control shaft includes a locking body, a switch, a hook, a spring, a bearing, and a magnet. The control shaft may be connected with the track through a hook position. The window blind is controlled by attraction of the inside magnet and the outside magnet to achieve the effects of control of raising and lowering the window blind between two panes of glass and light modulation. The locking device is controlled the engagement and disengagement between the hook and the track by the switch to ensure the window blind stopping at any position and without sliding down.

Abstract: Disclosed are pyridazine derivatives represented by Formula I or pharmaceutically acceptable salts or hydrates thereof, pharmaceutical compositions comprising the compounds, methods of treating and/or preventing diseases or disorders associated with viral infections in patients using the compounds, and the use of the compounds in preparing the medicaments for treating and/or preventing diseases or disorders associated with viral infections. The compounds represented by Formula I have antiviral activity, especially anti-microRNA viral activity. Symbols in the compounds represented are described in the specification.

Abstract: The present invention relates to (1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-guanidino-2-hydroxy-cyclopentyl-1-carboxylic acid hydrates compounds, preparing methods thereof, pharmaceutical compositions containing said compounds and preparing methods thereof, and the clinical uses of said compounds as neuramidinase inhibitors for anti-influenza.

Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for predicting a future context of a computing device. In some implementations, a context daemon can use historical context information to predict future events and/or context changes. For example, the context daemon can analyze historical context information to predict user sleep patterns, user exercise patterns, and/or other user activity. In some implementations, a context client can register a callback for a predicted future context. For example, the context client can request to be notified ten minutes in advance of a predicted event and/or context change. The context daemon can use the prediction to notify a context client in advance of the predicted event.

Abstract: The invention relates to a tizoxanide carbamate compound of Formula I and a pharmaceutically acceptable salt, a hydrate or a solvate thereof, and their pharmaceutical use.

Abstract: The present invention relates to a compound of formula (I), a stereomeride, pharmaceutically acceptable salt, a solvate or an N-oxide thereof, a medicine composition comprising the compound, a method for preparing the compound, and a usage of the compound in treating diseases related to Hsp70. The diseases are preferably selected from tumors, neurodegenerative diseases, and allogeneic transplantation rejection and infection.

Abstract: Provided are piperazinyl pyrimidine derivatives of formula I having CCR4 antagonism, and the preparation method, pharmaceutical composition and use thereof in the preparation of a medicament. The medicament is useful for the treatment and prevention of CCR4-related diseases.

Abstract: The invention provides a composition comprising a nanofiber polymer in which the fibers of the nanofiber polymer arc aligned, and a molecule is covalcntly attached, either directly or through a linker, to the nanofiber polymer. This molecule is capable of either covalently or non-covalently attaching to a member selected from an extracellular matrix component, a growth factor, and combinations thereof. The invention also provides methods of making the composition and methods of using the compositions to add new tissue to a subject, such as a human.

Abstract: The present invention provides a compound of a general formula I, a stereomeride, pharmaceutically acceptable salt or a solvate thereof, a preparation method thereof, and usages in preparing medicines for preventing and/or treating diseases or symptoms caused by drug-resistant tumors or drug-resistant bacteria and in preparing medicines for preventing and/or treating diseases or symptoms related to tumors, neurodegenerative diseases, allogeneic transplantation rejection, and infection. Preferably, the diseases or symptoms related to tumors, neurodegenerative diseases, allogeneic transplantation rejection, and infection are diseases or symptoms caused by a heat shock protein 70 (Hsp70). The compound in the present invention is used for overcoming a difficult problem of drug resistance of tumors, improves the effect of tumor treatment, and provides a new medical strategy for clinical tumor treatment.

Abstract: The invention provides a compound of Formula I, an isomer, a pharmaceutically acceptable salt, or a solvate thereof, and use thereof in manufacture of a medicament for preventing and/or treating a drug-resistant tumor or disease or disorder caused by a drug-resistant bacterium, or use thereof in manufacture of a medicament for preventing and/or treating a tumor, a neurodegenerative disease, an allogeneic graft rejection, or an infection-associated disease or disorder; preferably, the tumor, neurodegenerative disease, allogeneic graft rejection, or infection-associated disease or disorder is a disease or disorder caused by Heat shock protein 70 (Hsp70). The compounds of the invention, which are a class of Hsp70 inhibitors having a novel structure and a high activity, solve the problem concerning drug resistance of tumors, enhance the effect of treating tumors, and provide a new medical strategy for treatment of tumors in clinic.