Patents by Inventor Sonia Rodriguez

Sonia Rodriguez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Scalable process for the preparation of a GlyT-1 Inhibitor
    Publication number: 20240083889
    Abstract: This invention relates to a synthetic method for the preparation of Compound 1 and precursors thereof. Compound 1 is prepared via reaction of isoxazole 2 with phenylether (R)-3-ONa.
    Type: Application
    Filed: August 24, 2023
    Publication date: March 14, 2024
    Inventors: Katrin BAER, Gisela BODENBACH, Jack Delbert BROWN, Rosemarie Karoline COLLET, Daniel HERKOMMER, Rogelio P. FRUTOS, Joe Ju GAO, Julia Regina GRIMM, Sandra KOCH, Sonia RODRIGUEZ, Svetlana SEHL-OLLENBERGER, Joshua Daniel SIEBER, Thomas G. TAMPONE, Ulrich THEIS, Dirk WEBER, Erik WEIS, Anke WILD
  • INTERMEDIATE COMPOUNDS AND METHODS
    Publication number: 20230183178
    Abstract: The present invention relates to compounds of (II) and an acceptable salt or hydrate thereof method of making same.
    Type: Application
    Filed: February 9, 2023
    Publication date: June 15, 2023
    Inventors: Phouvieng BEYER, Jason A. BRAZZILLO, Magnus ERIKSSON, Jon Charles LORENZ, Laurence J. NUMMY, Sonia RODRIGUEZ, Jolaine SAVOIE, Kanwar Pal Singh SIDHU, Joshua D. SIEBER, Thomas Gabriel TAMPONE, Zhulin TAN, Jun WANG, Li ZHANG, Weitong DONG, Pengtao ZHANG
  • Intermediate compounds and methods
    Patent number: 11603354
    Abstract: The present invention relates to compounds of (II) and an acceptable salt or hydrate thereof method of making same.
    Type: Grant
    Filed: July 14, 2021
    Date of Patent: March 14, 2023
    Inventors: Phouvieng Beyer, Jason A. Brazzillo, Weitong Dong, Magnus Eriksson, Jon Charles Lorenz, Laurence J. Nummy, Sonia Rodriguez, Jolaine Savoie, Kanwar Pal Singh Sidhu, Joshua D. Sieber, Thomas Gabriel Tampone, Zhulin Tan, Jun Wang, Li Zhang, Pengtao Zhang
  • INTERMEDIATE COMPOUNDS AND METHODS
    Publication number: 20210340101
    Abstract: The present invention relates to compounds of (II) and an acceptable salt or hydrate thereof method of making same.
    Type: Application
    Filed: July 14, 2021
    Publication date: November 4, 2021
    Inventors: Phouvieng BEYER, Jason A. BRAZZILLO, Weitong DONG, Magnus ERIKSSON, Jon Charles LORENZ, Laurence J. NUMMY, Sonia RODRIGUEZ, Jolaine SAVOIE, Kanwar Pal Singh SIDHU, Joshua D. SIEBER, Thomas Gabriel TAMPONE, Zhulin TAN, Jun WANG, Li ZHANG, Pengtao ZHANG
  • INTERMEDIATE COMPOUNDS AND METHODS
    Publication number: 20200369611
    Abstract: The present invention relates to compounds of (II) and an acceptable salt or hydrate thereof method of making same.
    Type: Application
    Filed: July 30, 2018
    Publication date: November 26, 2020
    Inventors: Phouvieng BEYER, Jason A. BRAZZILLO, Magnus ERIKSSON, Jon Charles LORENZ, Laurence J. NUMMY, Sonia RODRIGUEZ, Jolaine SAVOIE, Kanwar Pal Singh SIDHU, Joshua D. SIEBER, Thomas Gabriel TAMPONE, Zhulin TAN, June WANG, Li ZHANG
  • Chiral dihydrobenzooxaphosphole ligands and synthesis thereof
    Patent number: 10544177
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: January 28, 2020
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Jean-Nicolas Desrosiers, Daniel Robert Fandrick, Nizar Haddad, Guisheng Li, Nitinchandra D. Patel, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Zhulin Tan, Xiao-Jun Wang, Nathan K. Yee, Li Zhang, Yongda Zhang
  • NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF
    Publication number: 20190144475
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Inventors: Jean-Nicolas DESROSIERS, Daniel Robert FANDRICK, NIZAR HADDAD, Guisheng LI, Nitinchandra D. PATEL, Bo QU, Sonia RODRIGUEZ, Chris Hugh SENANAYAKE, Joshua Daniel SIEBER, Zhulin TAN, Xiao-Jun WANG, Nathan K. YEE, Li ZHANG, Yongda ZHANG
  • Chiral dihydrobenzooxaphosphole ligands and synthesis thereof
    Patent number: 10221203
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: March 5, 2019
    Assignee: Boehringer Ingelheim International Gmbh
    Inventors: Jean-Nicolas Desrosiers, Daniel Robert Fandrick, Nizar Haddad, Guisheng Li, Nitinchandra D. Patel, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Zhulin Tan, Xiao-Jun Wang, Nathan K. Yee, Li Zhang, Yongda Zhang
  • Chiral dihydrobenzoazaphosphole ligands and synthesis thereof
    Patent number: 10196413
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: February 5, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Soumik Biswas, Jean-Nicolas Desrosiers, Kendricks Lao, Hari P. R. Mangunuru, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Xiao-Jun Wang, Nathan K. Yee, Yongda Zhang
  • NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF
    Publication number: 20180155375
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Application
    Filed: December 6, 2017
    Publication date: June 7, 2018
    Inventors: Jean-Nicolas Desrosiers, Daniel Robert Fandrick, Nizar Haddad, Guisheng Li, Nitinchandra D. Patel, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Zhulin Tan, Xiao-Jun Wang, Nathan K. Yee, Li Zhang, Yongda Zhang
  • NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF
    Publication number: 20180155377
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Application
    Filed: December 5, 2017
    Publication date: June 7, 2018
    Inventors: Soumik Biswas, Jean-Nicolas Desrosiers, Kendricks Lao, Hari P.R. Mangunuru, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Xiao-Jun Wang, Nathan K. Yee, Yongda Zhang
  • Monophosphorus ligands and their use in cross-coupling reactions
    Patent number: 9096626
    Abstract: Phosphine ligands of the formula Ia, IB and mixtures thereof.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: August 4, 2015
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Nizar Haddad, Bo Qu, Sonia Rodriguez, Chris Senanayake, Wenjun Tang, Xudong Wei, Nathan K. Yee
  • Ruthenium catalysts and their use for asymmetric reduction of ketones
    Patent number: 9029540
    Abstract: Disclosed are novel ruthenium compounds of formula (Ia) and (Ib): wherein R1 and the moiety are defined herein. Also disclosed is a process for using these novel ruthenium compounds as catalysts for asymmetric hydrogenation and transfer hydrogenation of ketones with high reactivities and excellent selectivities.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: May 12, 2015
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Nizar Haddad, Heewon Lee, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake
  • Benzodioxane inhibitors of leukotriene production
    Patent number: 8946203
    Abstract: The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: February 3, 2015
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Asitha Abeywardane, Steven Richard Brunette, Michael J. Burke, Suresh R. Kapadia, Thomas Martin Kirrane, Matthew Russell Netherton, Hossein Razavi, Sonia Rodriguez, Anjan Saha, Robert Sibley, Lana Louise Smith-Keenan, Hidenori Takahashi, Michael Robert Turner, Jiang-Ping Wu, Erick Richard Roush Young, Qiang Zhang, Qing Zhang, Renee M. Zindell
  • NOVEL RUTHENIUM CATALYSTS AND THEIR USE FOR ASYMMETRIC REDUCTION OF KETONES
    Publication number: 20150005500
    Abstract: Disclosed are novel ruthenium compounds of formula (Ia) and (Ib): wherein R1 and the moiety are defined herein. Also disclosed is a process for using these novel ruthenium compounds as catalysts for asymmetric hydrogenation and transfer hydrogenation of ketones with high reactivities and excellent selectivities.
    Type: Application
    Filed: June 24, 2014
    Publication date: January 1, 2015
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Nizar HADDAD, Heewon LEE, Bo QU, Sonia RODRIGUEZ, Chris Hugh SENANAYAKE
  • PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR
    Publication number: 20140094610
    Abstract: The present invention is directed to an improved process for the preparation of Compounds of Formula (I) or salts thereof which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid or salt thereof which is useful in the treatment of HIV infection.
    Type: Application
    Filed: October 3, 2013
    Publication date: April 3, 2014
    Inventors: Wenjie LI, Philomen DECROOS, Keith R. FANDRICK, Joe Ju GAO, Nizar HADDAD, Zhi-Hui LU, Bo QU, Sonia RODRIGUEZ, Chris H. SENANAYAKE, Yongda ZHANG, Wenjun TANG
  • Preparation of dihydrothieno [3,2-D] pyrimidines and intermediates used therein
    Patent number: 8653282
    Abstract: The invention relates to improved methods of preparing dihydrothienopyrimidines of formula 1, and intermediates thereof, (I) wherein X is SO or SO2, preferably SO, and wherein RA, R1, R2, R3, R4 and R5 have the meanings given in the description. The methods according to this invention are more suitable for large-scale synthesis of said compounds than prior methods because the new synthetic process avoids distillation and chromatographic purification between steps and results in a higher overall yield of the desired product.
    Type: Grant
    Filed: October 15, 2008
    Date of Patent: February 18, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Rogelio Frutos, Dhileepkumar Krishnamurthy, Jason Alan Mulder, Sonia Rodriguez, Chris Hugh Senanayake, Thomas G. Tampone
  • BENZODIOXANE INHIBITORS OF LEUKOTRIENE PRODUCTION
    Publication number: 20130244996
    Abstract: The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
    Type: Application
    Filed: March 5, 2013
    Publication date: September 19, 2013
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Asitha ABEYWARDANE, Steven Richard BRUNETTE, Michael J. BURKE, Suresh R. KAPADIA, Thomas Martin KIRRANE, Matthew Russell NETHERTON, Hossein RAZAVI, Sonia RODRIGUEZ, Anjan SAHA, Robert SIBLEY, Lana Louise SMITH-KEENAN, Hidenori TAKAHASHI, Michael Robert TURNER, Jiang-Ping WU, Erick Richard Roush YOUNG, Qiang ZHANG, Qing ZHANG, Renee M. ZINDELL
  • Monophosphorus Ligands And Their Use In Cross-Coupling Reactions
    Publication number: 20130137902
    Abstract: Phosphine ligands of the formula Ia, IB and mixtures thereof.
    Type: Application
    Filed: March 31, 2011
    Publication date: May 30, 2013
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Nizar Haddad, Bo Qu, Sonia Rodriguez, Chris Senanayake, Wenjun Tang, Xudong Wei, Nathan K. Yee
  • Process for Synthesis of Intermediates Useful for Making Substituted Indazole and Azaindazole Compounds
    Publication number: 20110137042
    Abstract: Disclosed are processes for preparing compounds of formula (I): the compounds are useful as intermediates for preparing indazole and azaindazole substituted compounds.
    Type: Application
    Filed: December 1, 2010
    Publication date: June 9, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Hossein RAZAVI, Jonathan Timothy REEVES, Sonia RODRIGUEZ