Patents by Inventor Soo-Chang Song

Soo-Chang Song has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLY(ORGANOPHOSPHAZENE) HYDROGELS FOR DRUG DELIVERY, PREPARATION METHOD THEREOF AND USE THEREOF
    Publication number: 20090047348
    Abstract: A biodegradable and thermosensitive poly(organophosphazene) with a functional group, a preparation method thereof, and a use thereof for delivery of bioactive substances are provided.
    Type: Application
    Filed: May 17, 2008
    Publication date: February 19, 2009
    Applicant: Korea Institute of Science and Technology
    Inventors: Soo-Chang SONG, Mi-Ran PARK, Sun-Mi LEE
  • Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof
    Publication number: 20090022683
    Abstract: The present invention relates to a biodegradable and thermosensitive poly(organophosphazene) with a functional group, a preparation method thereof, and a use thereof for delivery of bioactive substances. According to the present invention, poly(organophosphazene) is a phosphagen-based polymer showing biodegradability, thermosensitivity, and sol-gel phase transition depending on temperature change, whereby when administered into a living body with bioactive substances such as drugs, the poly(organophosphazene) forms a gel-phase at body temperature to be capable of controlled release of the bioactive substances. Further, the poly(organophosphazene) has functional groups to chemically bind with bioactive substances through an ionic bond, covalent bond, or coordinate covalent bond to be capable of a sustained release of the bioactive substances due to its good binding property. Therefore, the poly(organophosphazene) is useful as a delivery material for bioactive substances.
    Type: Application
    Filed: November 3, 2006
    Publication date: January 22, 2009
    Applicant: KIST
    Inventors: Soo-Chang Song, Sun-Mi Lee, Chang-Won Kim, Mi-Ran Park
  • Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same
    Patent number: 7259225
    Abstract: Disclosed are polyphosphazenes of Formula 1 showing a sol-gel behavior with a temperature change, a preparation method thereof, and injectable thermosensitive polyphosphazene hydrogels using the same
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: August 21, 2007
    Assignee: Korea Institute of Science and Technology
    Inventors: Soo-Chang Song, Bae-Houn Lee
  • Thermosensitive poly (organophosphazenes), preparation method thereof and injectable thermosensitive polyphosphazene hydrogels using the same
    Publication number: 20050020808
    Abstract: Disclosed are polyphosphazenes of Formula 1 showing a sol-gel behavior with a temperature change, a preparation method thereof, and injectable thermosensitive polyphosphazene hydrogels using the same.
    Type: Application
    Filed: April 28, 2004
    Publication date: January 27, 2005
    Applicant: Korea Institute of Science and Technology
    Inventors: Soo-Chang Song, Bae-Houn Lee
  • Thermosensitive cyclotriphosphazene derivatives and a preparation method thereof
    Patent number: 6417383
    Abstract: The present invention relates to novel cyclotriphosphazene derivatives represented by Formula (1) and a preparation method thereof wherein HNA is an amino acid group selected from glycine group(—NHCH2COO−), aminomalonic acid group(—NHCH(COO−)2), aspartic acid group (—NHCH(CH2COO−)COO−) and glutamic acid group (—NHCH(CH2CH2COO−)COO−), m is a repeating unit of poly(alkoxyethyleneglycol) selected from 2, 7, 12 and 16, and n is an integer representing number of alkyl carbons and selected from 0, 1, and 3.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: July 9, 2002
    Assignee: Korea Institute of Science and Technology
    Inventors: Youn Soo Sohn, Soo-Chang Song, Sang Beom Lee
  • Thermosensitive cyclotriphosphazene-platinum complex conjugate, its preparation method and anticancer agent containing the same
    Patent number: 6333422
    Abstract: The present invention provides a novel thermosensitive cyclotriphosphazene-platinum complex conjugates represented by Formula 1, wherein m is a repeating unit of poly(alkoxyethylene glycol) selected from the integers 2, 7 and 12; n represents the length of the alkyl chain selected from the integers 0, 1, 2 and 3; x represents the length of the anionic amino acid residue selected from the integers 0 (amino malonic acid derivatives), 1 (aspartic acid derivatives) and 2 (glutamic acid derivatives); A2 is a bidentate chelating diamine selected from the group consisting of 2,2-dimethyl-1,3-propanediamine (dmpda), trans(±)-1,2-diaminocyclohexane (dach) and 1,1-diaminomethylcyclohexane (dmach).
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: December 25, 2001
    Assignee: Korea Institute of Science and Technology
    Inventors: Youn Soo Sohn, Soo-Chang Song, Sang Beom Lee
  • Biodegradable and thermosensitive polyphosphazenes and their preparation method
    Patent number: 6319984
    Abstract: The present invention relates to novel biodegradable polyphosphazenes represented by Formula 1 and a preparation method thereof. Polyphosphazenes of the present invention not only have thermosensitivity and biodegradability simultaneously, but also their phase transition temperature and degradation rate can be controlled.
    Type: Grant
    Filed: April 11, 2000
    Date of Patent: November 20, 2001
    Assignee: Korea Institute of Science and Technology
    Inventors: Soo-Chang Song, Youn Soo Sohn, Bae Hoon Lee, Sang Beom Lee