Patents by Inventor Soren Kjaerulff

Soren Kjaerulff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120045757
    Abstract: According to an embodiment of the invention, an apparatus to detect fluorescence from a sample is disclosed. The apparatus comprises a sample plane onto which the sample is arranged, an excitation light unit including at least a light source to illuminate the sample, and a detection unit comprising at least a detector having at least 100,000 active detection elements to detect a fluorescence signal from the sample.
    Type: Application
    Filed: October 21, 2009
    Publication date: February 23, 2012
    Inventors: Søren Kjaerulff, Mette Elena Skindersø, Helle Frobøse Sørensen, Frans Ejner Ravn, Martin Glensbjerg
  • Publication number: 20110312013
    Abstract: The present invention provides simple, rapid methods and procedures for analyzing cells, hereunder quantitative and qualitative assessment of cells. The present invention relates to the use of N-(9-acridinyl)maleimide (NAM) or to the use of 7-diethylamino-3-((4?-(iodoacetyl)amino)phenyl)-4-methylcoumarin (CPI), particularly detectable upon its reaction with species (e.g., sulphur-containing species) present in higher concentrations in intact (e.g., living) cells than in non-intact (e.g., dead) cells. The present invention also relates to the use of NAM or to the use of 7-diethylamino-3-((4?-(iodoacetyl)amino)phenyl)-4-methylcoumarin (CPI), particularly detectable upon its reaction with species present in intact and/or non-intact cells. Moreover, the present invention relates to the use of measuring techniques and/or instruments coupled with the use of NAM or with the use of 7-diethylamino-3-((4?-(iodoacetyl)amino)phenyl)-4-methylcoumarin (CPI).
    Type: Application
    Filed: July 14, 2009
    Publication date: December 22, 2011
    Applicant: CHEMOMETEC A/S
    Inventors: Mette Elena Skindersø, Helle Frobøse Sørensen, Søren Kjærulff
  • Publication number: 20110312012
    Abstract: The present invention provides simple, rapid methods and procedures for analyzing cells, hereunder quantitative and qualitative assessment of cells, such as viability. The present invention relates to the use of various optionally substituted reporter compounds particularly detectable upon their reaction with thiol-containing species present in higher concentrations in intact (e.g., living) cells than in non-intact (e.g., dead, stressed and apoptotic) cells. The present invention also relates to the use of various optionally substituted reporter compounds particularly detectable upon their reaction with species present in intact and/or non-intact cells. Moreover, the present invention relates to the use of measuring techniques and/or instruments coupled with the use of various optionally substituted reporter compounds. The invention further relates to compositions used in methods for analyzing cells, such as a composition comprising N-(7-dimethylamino-4-methyl-3-coumarinyl)-maleimide (DACM).
    Type: Application
    Filed: July 13, 2009
    Publication date: December 22, 2011
    Applicant: ChemoMetec A/S
    Inventors: Mette Elena Skinderso, Helle Frobøse Sørensen, Søren Kjærulff
  • Publication number: 20110171694
    Abstract: The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered stability, in particular at high temperatures and/or at low pH relative, and/or low Ca2+ to the parent alpha-amylase.
    Type: Application
    Filed: March 21, 2011
    Publication date: July 14, 2011
    Applicant: Novozymes A/S
    Inventors: Thomas Thisted, Soren Kjaerulff, Carsten Andersen, Claus Crone Fuglsang
  • Publication number: 20110086132
    Abstract: A transgenic plant cell expressing a maltogenic amylase (such as Novamyl®) or a beta-amylase; a transgenic plant regenerated from said cell; seeds generated from such plant where said seeds comprise a maltogenic amylase or a beta-amylase and the use of said seeds, optionally in ground form, for catalyzing an industrial process, such as e.g. in baking. The maltogenic amylase providing an anti staling effect in bread produced from the seeds in question.
    Type: Application
    Filed: December 15, 2010
    Publication date: April 14, 2011
    Applicant: Novozymes A/S
    Inventors: Jack Bech Nielsen, Søren Kjaerulff
  • Publication number: 20110076741
    Abstract: The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase.
    Type: Application
    Filed: November 23, 2010
    Publication date: March 31, 2011
    Applicant: Novozymes A/S
    Inventors: Carsten Andersen, Christel Thea Jorgensen, Henrik Bisgard-Frantzen, Allan Svendsen, Soren Kjaerulff
  • Patent number: 7867746
    Abstract: The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: January 11, 2011
    Assignee: Novozymes A/S
    Inventors: Carsten Andersen, Christel Thea Jorgensen, Henrik Bisgard-Frantzen, Allan Svendsen, Soren Kjaerulff
  • Publication number: 20100190681
    Abstract: The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered stability, in particular at high temperatures and/or at low pH relative, and/or low Ca2+ to the parent alpha-amylase.
    Type: Application
    Filed: April 12, 2010
    Publication date: July 29, 2010
    Applicant: NOVOZYMES A/S
    Inventors: THOMAS THISTED, SOREN KJAERULFF, CARSTEN ANDERSEN, CLAUS CRONE FUGLSANG
  • Patent number: 7736589
    Abstract: A method for testing cleaning effect of a compound or compositions is disclosed. The method comprises: (a) Preparing a liquid sample of less than 10 ml comprising the test compound, (b) applying liquid sample to a stained surface, (c) applying mechanical stress to the stained surface by contacting it with a body present in the liquid sample, (d) evaluating the cleaning effect of applying solution and mechanical stress on the stained surface.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: June 15, 2010
    Assignee: Novozymes A/S
    Inventors: Georg Rudolf Theobald Bechmann, Steven Paul Georges Cooremans, Michael Godskesen, Soren Kjaerulff
  • Patent number: 7713723
    Abstract: The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered stability, in particular at high temperatures and/or at low pH relative, and/or low Ca2+ to the parent alpha-amylase.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: May 11, 2010
    Assignee: Novozymes A/S
    Inventors: Thomas Thisted, Soren Kjaerulff, Carsten Andersen, Claus Crone Fuglsang
  • Publication number: 20100099161
    Abstract: The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered stability, in particular at high temperatures and/or at low pH relative, and/or low Ca2+ to the parent alpha-amylase.
    Type: Application
    Filed: December 22, 2009
    Publication date: April 22, 2010
    Applicant: Novozymes A/S
    Inventors: Thomas Thisted, Soren Kjaerulff, Carsten Andersen, Claus Crone Fuglsang
  • Patent number: 7656691
    Abstract: The present invention relates to an apparatus and a method for converting power from a power input to a DC output current or voltage, where a first feedback circuit a traditional feedback. The converter type is a resonant DC-DC converter. The scope of the invention is to reach a high effective and fast responding switch mode power supply. This can be achieved with an apparatus or method comprising a second feedback circuit leading a signal from a serial resonance capacitor(s) to a reference input terminal at the control circuit, which second feedback circuit contains a signal depending on the actual change in charge of the resonant capacitor(s). This means that at high load, a very powerful signal will be transmitted through the second feedback at the control circuit that will change the operation of the circuit into a charge mode operation.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: February 2, 2010
    Assignee: Bang & Olufsen A/S
    Inventors: Runo Nielsen, Soren Kjaerulff Christensen
  • Publication number: 20100022433
    Abstract: The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered stability, in particular at high temperatures and/or at low pH relative, and/or low Ca2+ to the parent alpha-amylase.
    Type: Application
    Filed: September 24, 2009
    Publication date: January 28, 2010
    Applicant: NOVOZYMES A/S
    Inventors: THOMAS THISTED, SOREN KJAERULFF, CARSTEN ANDERSEN, CLAUS CRONE FUGLSANG
  • Publication number: 20090263881
    Abstract: The invention relates to a variant of a parent Termamyl-like ?-amylase, which exhibits an alteration in at least one of the following properties relative to said parent ?-amylase: i) improved pH stability at a pH from 8 to 10.5; and/or ii) improved Ca2+ stability at pH 8 to 10.5, and/or iii) increased specific activity at temperatures from 10 to 60° C.
    Type: Application
    Filed: December 10, 2007
    Publication date: October 22, 2009
    Applicant: Novozymes A/S
    Inventors: Torben Vedel Borchert, Allan Svendsen, Carsten Andersen, Bjarne Nielsen, Torben Lauesgaard Nissen, Soren Kjaerulff
  • Publication number: 20090214703
    Abstract: A transgenic plant cell expressing a maltogenic amylase (such as Novamyl®) or a beta-amylase; a transgenic plant regenerated from said cell, seeds generated from such plant where said seeds comprise a maltogenic amylase or a beta-amylase and the use of said seeds, optionally in ground form, for catalyzing an industrial process, such as e.g. in baking. The maltogenic amylase providing an anti staling effect in bread produced from the seeds in question.
    Type: Application
    Filed: January 28, 2008
    Publication date: August 27, 2009
    Applicant: Novozymes A/S
    Inventors: Jack Bech Nielsen, Soren Kjaerulff
  • Publication number: 20090203109
    Abstract: The invention relates to a variant of a parent Termamyl-like ?-amylase, comprising mutations in two, three, four, five or six regions/positions. The variants have increased stability at high temperatures (relative to the parent). The invention also relates to a DNA construct comprising a DNA sequence encoding an ?-amylase variant of the invention, a recombinant expression vector which carries a DNA construct of the invention, a cell which is transformed with a DNA construct of the invention, the use of an ?-amylase variant of the invention for washing and/or dishwashing, textile desizing, starch liquefaction, a detergent additive comprising an ?-amylase variant of the invention, a manual or automatic dishwashing detergent composition comprising an ?-amylase variant of the invention, a method for generating a variant of a parent Termamyl-like ?-amylase, which variant exhibits increased.
    Type: Application
    Filed: April 2, 2009
    Publication date: August 13, 2009
    Applicant: Novozymes A/S
    Inventors: Allan Svendsen, Soren Kjaerulff, Henrik Bisgaard-Frantzen, Carsten Andersen
  • Publication number: 20090155882
    Abstract: The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase.
    Type: Application
    Filed: November 2, 2007
    Publication date: June 18, 2009
    Applicant: Novozymes A/S
    Inventors: Carsten Andersen, Christel Thea Jorgensen, Henrik Bisgard-Frantzen, Allan Svendsen, Soren Kjaerulff
  • Publication number: 20090128977
    Abstract: The present invention relates to a method for protecting electronic products, which electronic product comprises an Ethernet connector, where the Ethernet connector comprises a protection circuit, which circuit comprises at least one capacitor and at least one resister, where the Ethernet connector is used to protect against high energy transients, where the Ethernet connector comprises a protection circuitry. Where the Ethernet connector comprises a protection circuitry, which protection circuitry is characterized in that in the protection circuitry is the electrically product ground and Ethernet ground connected by at least a VDR (Voltage Dependant Resistor), which VDR is connected between the Ethernet ground and the product ground in the protection circuitry.
    Type: Application
    Filed: November 21, 2008
    Publication date: May 21, 2009
    Inventor: Soren Kjaerulff Christensen
  • Publication number: 20090098592
    Abstract: A method is described for releasing a soluble or membrane associated intracellular protein of interest (POI) comprising the steps of: providing a cell comprising a soluble or membrane associated intracellular POI; contacting the cell with a membrane extracting composition; and causing the POI to be released from the cell under conditions sufficient for the specific release of the POI and in a soluble form.
    Type: Application
    Filed: October 1, 2008
    Publication date: April 16, 2009
    Inventors: Claus Lindvald JOHANSEN, Soren Kjaerulff, Susan Mampusta Madrid, Henrik Pedersen, Charlotte Horsmans Poulsen, Masoud Rajabi Zargahi
  • Patent number: 7455990
    Abstract: A method is described for releasing a soluble or membrane associated intracellular protein of interest (POI) comprising the steps of: providing a cell comprising a soluble or membrane associated intracellular POI; contacting the cell with a membrane extracting composition; and causing the POI to be released from the cell under conditions sufficient for the specific release of the POI and in a soluble form.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: November 25, 2008
    Assignee: Danisco A/S
    Inventors: Claus Lindvald Johansen, Søren Kjaerulff, Susan Mampusta Madrid, Henrik Pedersen, Charlotte Horsmans Poulsen, Masoud Rajabi Zargahi