Abstract: The present application provides a two phase immiscible system for the pretreatment of embedded biological samples comprising placing at least one support having an embedded biological sample on its surface into a pretreatment container, adding to the pretreatment container at least one reagent forming a layer, adding a carrier composition to the pretreatment container, such that reagent forming layer is formed on the top of the carrier composition, and in an amount such that the at least one reagent forming layer contacts at least a portion of the embedded biological sample. Pretreatment of the embedded biological samples can include removal of embedding medium from embedded biological, target retrieval and enzyme blocking samples before staining histochemical analysis or other processes. The system also includes an apparatus and processes of automation of the pretreatment methods.

Abstract: The present disclosure includes a hinge assembly for use in a hinged attachment of a panel relative to a frame and providing movement of the panel relative to the frame. A link which provides an extension or reach motion and positioning of the assembly, shown for purposes of illustration and not limitation in the form of a gooseneck arm, is provided in the hinge assembly to facilitate an extended range of motion of the hinge assembly. A first spherical bearing assembly and a second spherical bearing assembly are operatively associated with a bearing end of the link to provide multiple degrees of motion while securely retaining the panel relative to the frame. The hinge is intended to provide universal application of a single version of a hinge which can be used in multiple locations as facilitated by the multiple degrees of motion provided by the bearing end of the link.

Abstract: The invention relates to a method for renovation and replacement of existing underground pipes and/or the installation of new pipes by using module pipes. The method comprises the step of screwing a second and further module pipe together with the first or consecutive module pipe, if the first or consecutive module pipe has mainly been pushed or pulled into the existing underground pipe.

Abstract: The present disclosure includes a hinge assembly for use in a hinged attachment of a panel relative to a frame and providing movement of the panel relative to the frame. A link which provides an extension or reach motion and positioning of the assembly, shown for purposes of illustration and not limitation in the form of a gooseneck arm, is provided in the hinge assembly to facilitate an extended range of motion of the hinge assembly. A first spherical bearing assembly and a second spherical bearing assembly are operatively associated with a bearing end of the link to provide multiple degrees of motion while securely retaining the panel relative to the frame.

Abstract: The invention relates to a method for renovation and replacement of existing under-ground pipes and/or the installation of new pipes by using module pipes. The method comprises the step of screwing a second and further module pipe together with the first or consecutive module pipe, if the first or consecutive module pipe has mainly been pushed or pulled into the existing underground pipe.

Abstract: The present invention relates to a dosage regime of a peptide analogues of [alpha]-melanocyte-stimulating hormone ([alpha]-MSH), which possesses an increased efficacy compared to the native [alpha]-MSH peptide in the treatment or prevention of kidney injury or disease.

Abstract: The invention describes peptide analogues of ?-melanocyte-stimulating hormone (?-MSH), which possess an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.

Abstract: The present invention relates to a dosage regime of a peptide analogues of [alpha]-melanocyte-stimulating hormone ([alpha]-MSH), which possesses an increased efficacy compared to the native [alpha]-MSH peptide in the treatment or prevention of kidney injury or disease.

Abstract: The present invention relates to a dosage regime of a peptide analogues of [alpha]-melanocyte-stimulating hormone ([alpha]-MSH), which possesses an increased efficacy compared to the native [alpha]-MSH peptide in the treatment or prevention of kidney injury or disease.

Abstract: The present application provides a two phase immiscible system for the pretreatment of embedded biological samples comprising placing at least one support having an embedded biological sample on its surface into a pretreatment container, adding to the pretreatment container at least one reagent forming a layer, adding a carrier composition to the pretreatment container, such that reagent forming layer is formed on the top of the carrier composition, and in an amount such that the at least one reagent forming layer contacts at least a portion of the embedded biological sample. Pretreatment of the embedded biological samples can include removal of embedding medium from embedded biological, target retrieval and enzyme blocking samples before staining histochemical analysis or other processes. The system also includes an apparatus and processes of automation of the pretreatment methods.

Abstract: The invention describes peptide analogues of ?-melanocyte-stimulating hormone (?-MSH), which possess an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.

Abstract: The invention describes peptide analogues of ?-melanocyte-stimulating hormone (?-MSH), which possess an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.

Abstract: The invention describes peptide analogues of a-melanocyte-stimulating hormone (a-MSH), which posses an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.

Abstract: There is described a tubular insert for a magnetic inductive flowmeter, a production method for such a tubular insert and a flowmeter. The tubular insert essentially comprises an electrically-insulating material, in particular, rubber, reinforced with a metal mesh, at least in a measuring section. The tubular metal mesh comprises one or more mesh sections, pre-prepared from sheet mesh by stamping, bending and welding butt edges running essentially parallel to the tube axis such as to form an essentially tubular metal mesh. The tubular metal grid is embedded in the electrically-insulating material passing therethrough and the electrically-insulating material essentially covers the inner and out surfaces of the tubular material. A robust, tubular insert is thus achieved, with a corresponding cheap production cost.

Abstract: There is described a tubular insert for a magnetically inductive flowmeter, a production method for said type of tubular insert and a flowmeter. The tubular insert is made of, essentially, an electrically-insulating material, in particular, rubber, which is reinforced by a tubular molding part made of a dimensionally stable plastic which is based on polymers, at least in a measuring section. The tubular molding part is embedded in the electrically-insulating rubber material by a press or casting method such that the electrically-insulating, rubber material essentially covers the inner surfaces of the tubular molding part. An economical to produce, robust, tubular insert is thus achieved.

Abstract: The invention describes peptide analogues of a-melanocyte-stimulating hormone (a-MSH), which posses an increased efficacy compared to the native ?-MSH peptide. The ?-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to ?-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.

Abstract: There is described a tubular insert for a magnetically inductive flowmeter, a production method for said type of tubular insert and a flowmeter. The tubular insert is made of, essentially, an electrically-insulating material, in particular, rubber, which is reinforced by a tubular moulding part made of a dimensionally stable plastic which is based on polymers, at least in a measuring section. The tubular moulding part is embedded in the electrically-insulating rubber material by a press or casting method such that the electrically-insulating, rubber material essentially covers the inner surfaces of the tubular moulding part. An economical to produce, robust, tubular insert is thus achieved.

Abstract: A magnetic inductive flowmeter having a measuring distance that is surrounded by a wall; a magnetic field generating device, and; an electrode device, which has at least one electrode on the inside of the wall and an electrode connection on the outside of the wall. The electrode connection is connected to the electrode by a plug-type connection, and the electrode connection fixes the electrode to the wall.

Abstract: There is described a tubular insert for a magnetic inductive flowmeter, a production method for such a tubular insert and a flowmeter. The tubular insert essentially comprises an electrically-insulating material, in particular, rubber, reinforced with a metal mesh, at least in a measuring section. The tubular metal mesh comprises one or more mesh sections, pre-prepared from sheet mesh by stamping, bending and welding butt edges running essentially parallel to the tube axis such as to form an essentially tubular metal mesh. The tubular metal grid is embedded in the electrically-insulating material passing therethrough and the electrically-insulating material essentially covers the inner and out surfaces of the tubular material. A robust, tubular insert is thus achieved, with a corresponding cheap production cost.

Abstract: Method of evaluating perception intensity of an audio input signal (IS) comprising the steps of receiving the audio input signal (IS), estimating a time variant distribution function (TVDF) on the basis of said audio input signal (IS) or a derivative thereof, determining the perception intensity as at least one perception intensity estimate (PIE) on the basis of said estimated time variant distribution function (TVDF). According to the invention perception intensity has been obtained on the basis of a time variant distribution function. Thereby, an advantageous universal and flexible determination of perception intensity is obtained. The universal applicability is basically obtained due to the fact that a distribution function may match and describe audio input signal of very different nature. Thus, according to the invention even speech, music and noise may be evaluated on the basis of a distribution function.