Abstract: The present invention provides a novel reference standard, comprising of activated-quenched polysaccharide, for quantifying polysaccharide content in a vaccine composition using nephelometry. The invention also provides a method for preparing the activated-quenched polysaccharide, for use as a reference standard. Further, a nephelometry based method for quantifying the polysaccharides in a multivalent conjugate vaccine is also provided. The reference standard of the present invention, comprising of the activated-quenched polysaccharide, is stable and can be used for accurate quantification of polysaccharides through nephelometry.

Abstract: A system and method of igniting a coal air-fuel mixture, including a burner having a burner tube operable to carry a flowing mixture of fuel and air to a furnace for combustion therein and a first flow directing device disposed within the tube, operable to direct a first portion of the flowing fuel and air mixture to a location in the burner tube. The system also includes a laser igniter within the burner tube, the laser igniter including a laser tube having a first end with a laser light input and a second end with a light output, and a laser light source operably coupled to the laser light input. The laser light source, including a laser. The laser ignitor directing photons from the light output at the location in the burner tube to ignite at least a part of the first portion of the fuel.

Abstract: A medical gown includes a main body having a neck edge, a first side edge, and a second side edge. The first side edge may extend from the neck edge. The second side edge may extend from the neck edge, opposite the first side edge. The neck edge may define a neck engagement feature between the first and second side edges. The medical gown may further include a first strap feature coupled with the main body and defining a first loop with the first side edge. The medical gown may further include a second strap feature coupled with the main body and defining a second loop with the second side edge.

Abstract: The present invention relates to an indole compound of Formula (I) or pharmaceutically acceptable salt thereof, and process for the preparation thereof. The present invention also relates to a pharmaceutical composition of indole compound of Formula (I) or pharmaceutically acceptable salt thereof for treating mycobacterial infection or antimalarial infection or antifungal infection in a subject in need thereof.

Abstract: Performing container scaling and migration for container-based microservices is provided. A first set of features is extracted from each respective microservice of a plurality of different microservices. A number of containers required at a future point in time for each respective microservice of the plurality of different microservices is predicted using a trained forecasting model and the first set of features extracted from each respective microservice. A scaling label and a scaling value are assigned to each respective microservice of the plurality of different microservices based on a predicted change in a current number of containers corresponding to each respective microservice according to the number of containers required at the future point in time for each respective microservice.

Abstract: Gas distribution apparatuses, e.g., showerheads, comprise passages having a first conical bore section, a small bore section, and a second conical bore section. The first conical bore sections comprise a first non-perpendicular wall angle relative to a back surface of a faceplate. The second conical bore sections comprise a second non-perpendicular angle to a front surface of the faceplate. The conical sections including non-perpendicular angles are effective to mitigate and/or eliminate changes in flow parameters through the passages after bead blast processes.

Abstract: Disclosed herein are personal protective equipment (PPE) storage, dispensing, and/or donning systems, devices, and methods for using same. In many embodiments, the disclosed storage, dispensing, and/or donning systems, devices, and methods include one or more devices or sub-systems for monitoring PPE stored at or in the system. In many embodiments, the storage, dispensing, and/or donning system may include one or more indicator for aiding a user in selecting items of PPE. Also disclosed are protective gowns for use with the disclosed storage, dispensing, and/or donning systems, wherein the gowns may include one or more features or structures to aid in storing, dispensing, or donning the gown.

Abstract: The present disclosure relates to multivalent pneumococcal vaccine compositions comprising capsular pneumococcal polysaccharide serotypes each individually conjugated to carrier proteins. When conjugated, the combination of the capsular pneumococcal polysaccharide serotype and the carrier protein is referred to herein as a polysaccharide-protein conjugate. The pneumococcal vaccine compositions may further comprise one or more of the following: a pharmaceutically acceptable carrier, a pharmaceutically acceptable diluent, a buffer, a preservative, a stabilizer, an adjuvant, and/or a lyophilization excipient. Methods of making and administering the pneumococcal vaccine compositions described herein are also provided.

Abstract: The disclosure generally relates to the detection of symmetrical dimethylarginine (SDMA). More particularly, the disclosure relates to the detection of SDMA using a solid phase. The disclosure provides devices, reagents, kits and methods for detecting symmetrical dimethyl arginine (SDMA) in sample, such as a biological sample from an animal. The method includes detecting the presence or amount of SDMA in the sample by using an immunoassay format, such as a competitive immunoassay. The assay includes the use of antibodies to SDMA that are specific for SDMA and that have less affinity for other arginine derivatives.

Abstract: A medical gown includes a main body having a neck edge, a first side edge, and a second side edge. The first side edge may extend from the neck edge. The second side edge may extend from the neck edge, opposite the first side edge. The neck edge may define a neck engagement feature between the first and second side edges. The medical gown may further include a first strap feature coupled with the main body and defining a first loop with the first side edge. The medical gown may further include a second strap feature coupled with the main body and defining a second loop with the second side edge.

Abstract: A medical gown includes a main body having a neck edge, a first side edge, and a second side edge. The first side edge may extend from the neck edge. The second side edge may extend from the neck edge, opposite the first side edge. The neck edge may define a neck engagement feature between the first and second side edges. The medical gown may further include a first strap feature coupled with the main body and defining a first loop with the first side edge. The medical gown may further include a second strap feature coupled with the main body and defining a second loop with the second side edge.

Abstract: A medical gown includes a main body having a neck edge, a first side edge, and a second side edge. The first side edge may extend from the neck edge. The second side edge may extend from the neck edge, opposite the first side edge. The neck edge may define a neck engagement feature between the first and second side edges. The medical gown may further include a first strap feature coupled with the main body and defining a first loop with the first side edge. The medical gown may further include a second strap feature coupled with the main body and defining a second loop with the second side edge.

Abstract: A mixing structure can include a body having first conduits, mixture conduits, and second conduits extending through the body to the internal volume. The first conduits may be closer to a first side of the body than the mixture conduits and the second conduits. The second conduits may closer to another side of the body than the first conduits and the mixture conduits. The internal volume may receive liquid streams from an injector. The first conduits and the second conduits may receive gas streams from outside the body. The body may thermally modify the gas streams and entrain the gas streams into the liquid streams in the internal volume. The mixture conduits may be positioned to direct the gas streams entrained into the liquid streams out of the body in directions directed toward the second side of the body and away from the first side of the body.

Abstract: The present disclosure relates to multivalent pneumococcal vaccine compositions comprising capsular pneumococcal polysaccharide serotypes each individually conjugated to carrier proteins. When conjugated, the combination of the capsular pneumococcal polysaccharide serotype and the carrier protein is referred to herein as a polysaccharide-protein conjugate. The pneumococcal vaccine compositions may further comprise one or more of the following; a pharmaceutically acceptable carrier, a pharmaceutically acceptable diluent, a buffer, a preservative, a stabilizer, an adjuvant, and/or a lyophilization excipient. Methods of making and administering the pneumococcal vaccine compositions described herein are also provided.

Abstract: A fuel and gas mixing structure for an engine is provided. This mixing structure includes a body configured to be positioned between a fuel injector and a cylinder of an engine. The body defines an interior volume that is configured to receive gas (e.g., air) from outside the body and to receive one or more streams of fuel from the fuel injector in the interior volume. The body also includes one or more upper channels and one or more lower channels that are configured to provide a substantially similar amount of flow relative to each other to the interior volume The body also defines one or more mixture conduits configured to conduct plumes of the fuel and gas, while mixing, from the interior volume to one or more exit ports and therethrough to the cylinder.

Abstract: A medical gown includes a main body having a neck edge, a first side edge, and a second side edge. The first side edge may extend from the neck edge. The second side edge may extend from the neck edge, opposite the first side edge. The neck edge may define a neck engagement feature between the first and second side edges. The medical gown may further include a first strap feature coupled with the main body and defining a first loop with the first side edge. The medical gown may further include a second strap feature coupled with the main body and defining a second loop with the second side edge.

Abstract: The disclosure generally relates to the detection of symmetrical dimethylarginine (SDMA). More particularly, the disclosure relates to the detection of SDMA using a solid phase. The disclosure provides devices, reagents, kits and methods for detecting symmetrical dimethyl arginine (SDMA) in sample, such as a biological sample from an animal. The method includes detecting the presence or amount of SDMA in the sample by using an immunoassay format, such as a competitive immunoassay. The assay includes the use of antibodies to SDMA that are specific for SDMA and that have less affinity for other arginine derivatives.

Abstract: A system and method of igniting a coal air-fuel mixture, including a burner having a burner tube operable to carry a flowing mixture of fuel and air to a furnace for combustion therein and a first flow directing device disposed within the tube, operable to direct a first portion of the flowing fuel and air mixture to a location in the burner tube. The system also includes a laser igniter within the burner tube, the laser igniter including a laser tube having a first end with a laser light input and a second end with a light output, and a laser light source operably coupled to the laser light input. The laser light source, including a laser. The laser ignitor directing photons from the light output at the location in the burner tube to ignite at least a part of the first portion of the fuel.

Abstract: Performing container scaling and migration for container-based microservices is provided. A first set of features is extracted from each respective microservice of a plurality of different microservices. A number of containers required at a future point in time for each respective microservice of the plurality of different microservices is predicted using a trained forecasting model and the first set of features extracted from each respective microservice. A scaling label and a scaling value are assigned to each respective microservice of the plurality of different microservices based on a predicted change in a current number of containers corresponding to each respective microservice according to the number of containers required at the future point in time for each respective microservice.

Abstract: An apparatus includes a rim, a tire, and an energy harvesting component. The rim is configured to rotate and move. The tire is coupled to the rim. The tire when inflated is configured to transfer force to the rim resulting from compressive force acting on a portion of the tire making contact with a road. The energy harvesting component is positioned on the rim and configured to capture a kinetic energy in response to the compressive force acting on the portion of the tire making contact with the road as the rim rotates.