Abstract: A process using a three-piece mold for making a three-dimensionally shaped glass article having a flat area and a curved/bend area is disclosed. The process includes placing a glass sheet on a mold having a shaping surface with a desired surface profile for the shaped glass article including a flat area and a bend area, moving a flat area plunger toward the glass sheet to compress the glass sheet, heating a portion of the glass sheet corresponding to an area above the bend area of the mold to a temperature above a forming temperature, and moving a bend area plunger toward the heated glass sheet to compress the heated glass sheet. A temperature of the glass sheet in the area above the bend area of the mold is higher than a temperature of the glass sheet in the area above the flat area of the mold when compressing the heated glass sheet with the bend area plunger.

Abstract: The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.

Abstract: The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).

Abstract: Various aspects are discussed, for example, a method is decsribed for authentication of devices in a wireless network involving NFC (Near Field Communication), wherein a device periodically switches its mode from a read mode, in which it is able to receive authentication data from one or more other devices, to a write mode, in which it sends out authentication data to the one or more other devices, according to a random time slot scheme. The device authenticates itself after having received authentication data from another device during the read mode, and the device switches permanently its mode to the write mode after being authenticated.

Abstract: The present invention relates to novel crystalline polymorphic forms of Vilazodone hydrochloride of formula (I). This present invention further provides the process for the preparation of novel polymorphic forms of Vilazodone hydrochloride.

Abstract: A method, system, apparatus, and computer-readable medium are provided for performing read-ahead operations for sequential read operations. A method includes maintaining a bitmap including a plurality of bits, each bit corresponding to a sector of the disk cache and containing data indicating whether the corresponding sector is valid and can be used to satisfy read requests. The method includes receiving a request to read a sector of the disk cache, and in response, identifying a bit in the bitmap that corresponds to the requested sector. Further, the method includes determining whether the disk cache contains valid data for a sector previous to the requested sector by examining a bit in the bitmap previous to the bit that corresponds to the requested sector, and in response, reading sequentially into the disk cache sectors of the disk cache corresponding to bits in the bitmap following the bit corresponding to the requested sector.

Abstract: The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for their use, and their pharmaceutical compositions.

Abstract: The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.

Abstract: An alignment pin assembly for a surgical stapler includes an alignment pin configured to be advanced prior to actuation of a stapler and an end cap defining an opening configured to receive the alignment pin prior to actuation of the stapler. The end cap includes an alignment pin contact area formed about the opening configured to direct the alignment pin into the opening.

Abstract: A power distribution system includes a manager provided on a network controller and an agent provided on a line module. The manager is operable to receive a configuration for a port on the line module. A connection to the port is then detected by the agent and communicated to the manager. At least one of the manager and the agent determines that the connection is for a powered device that is operable to receive power and data through the port. The manager then classifies the powered device. If the manager determines that the classification of the powered device corresponds to the configuration of the port, the manager provides power to the powered device through the port according to an allocation for the powered device from a global power budget.

Abstract: A cooling subsystem is provided for dissipating heat from processor. The cooling subsystem includes a heat sink comprising an upper portion having a plurality of fins formed therein and a base portion fixed to the upper portion to form a vapor chamber in an enclosed volume between the upper portion and the base portion.

Abstract: The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and their pharmaceutical compositions.

Abstract: The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).

Abstract: Described herein are novel metal salts capable as nucleating agents for polyolefins. The present invention relates to such salts synthesized by reacting potassium hydroxide with carboxylic acids and further, to the achievement of high crystallization temperatures in polypropylene compositions upon dispersal therein of formulations containing one or more of the said metal salts.

Abstract: A method is provided for diagnosing an aircraft. The method includes: determining a location of a fault in the aircraft; determining a zone of the aircraft that is associated with the location of the fault; and generating an interactive three-dimensional user interface based on the zone, wherein the interactive three-dimensional user interface provides fault data of at least one of historical faults and current faults associated with the zone.

Abstract: Systems and methods for discrete signal synchronization based on a known bit pattern are described. In one aspect of the present subject matter, a discrete signal synchronization system is configured to synchronize a preprocessed discrete signal with a modified discrete signal. The system comprises a processor and a synchronization module coupled to the processor. The synchronization module comprises an extraction module and comparison module. The extraction module determines a bit pattern from the modified discrete signal using Discrete Wavelet Transformation (DWT) and Singular Value Decomposition (SVD). The comparison module compares the determined bit pattern with a known bit pattern of the preprocessed discrete signal and records a time point at which the determined bit pattern matches with the known bit pattern of the preprocessed discrete signal as a synchronization point.

Abstract: The present invention relates to novel compounds of formula (I), and their pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their pharmaceutically acceptable salts. The compounds of formula (I) are useful in the treatment of various disorders that are related to 5-HT4 receptors.

Abstract: The present invention relates to an improved process for the preparation of Tenofovir Disoproxil and its pharmaceutically acceptable salts comprising the steps of: a) esterifying Tenofovir with chloromethyl isopropyl carbonate in presence of a base, phase transfer catalyst and optionally dehydrating agent, in a suitable solvent; b) optionally purifying Tenofovir Disoproxil; and c) converting of Tenofovir Disoproxil into its pharmaceutically acceptable salts. The present invention further relates to a process for the preparation of Tenofovir by reacting 1-(6-amino-purin-9-yl)-propan-2-ol with toluene-4-sulfonic acid diethoxy phosphoryl methyl ester in presence of a base in a non-polar solvent medium followed by hydrolysis.

Abstract: The disclosure relates to a method of oxidation of an aliphatic C—H bond in an organic compound using CdO2 or ZnO2 nanoparticles as oxidizing agents. The instant disclosure relates to a method of oxidizing toluene using metal peroxide nanoparticles such as CdO2, ZnO2 as oxidizing agents to obtain oxidized products predominantly comprising benzaldehyde.

Abstract: A process for preparation of eletriptan hydrobromide having ?-form of formula (I) is described that includes reducing 3-((R)-1-methylpyrrolidin-2-yl)methyl)-5-((E)-2-(phenylsulfonyl)vinyl)-1H-indole of formula (II) in presence of a metal catalyst to the product of formula (III) and then converting to hydrobromide salt having ?-form of formula (I).