Abstract: Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases.

Abstract: A rotary spindle 4 for a power tool such as a hammer drill is disclosed. The spindle 4 comprises a first spindle part 402 for rotation about its longitudinal an axis by means of a motor and having an inwardly directed rim 406, and a second spindle part 404 for supporting a drill bit of the hammer drill and having an outwardly directed rim 410. The second spindle part 404 extends through an aperture 408 in the first spindle part 402 and rims 406, 410 cooperate with each other to prevent removal of the second spindle part 404 from the first spindle part 402. A circlip 414 locks the first and second spindle parts 402, 404 together and maintains o-rings 412 under compression.

Abstract: A battery protection and monitoring system includes a plurality of MAFET (Mechanically Actuated Field Effect Transistor) switches, wherein each MAFET switch among the MAFET switches is capable of switching from an open switch condition to a closed switch condition or vice versa, such that the plurality of MAFET switches are connectable to a battery. Such a system further includes one or more transistors associated with and which communicate electrically with at least one MAFET switch among the MAFET switches. A PPTC (Polymeric Positive Temperature Coefficient) device is also associated with the transistors and the MAFET switches, such that the PPTC device, the MAFET switches and the transistors operate in association with one another and the open switch condition or the closed switch condition of the plurality of MAFET switches to identify, monitor and thus prevent at least one dangerous condition associated with the battery.

Abstract: A resilient stop assembly for an impact tool includes first and second resiliently deformable parts, and a substantially rigid part situated between the deformable parts. Each of the first and second resiliently deformable parts and the substantially rigid part comprises: first and second opposite impact surfaces, at least one peripheral surface joining the impact surfaces, and an aperture extending entirely through the part between exit openings in the impact surfaces. The first impact surface of the second resiliently deformable part is separated from the second impact surface of the first resiliently deformable part by contact of those first and second impact surfaces with the substantially rigid part.

Abstract: A fastener outlet assembly for a fastener driving tool includes: an outlet passage arranged to expel fasteners from the assembly to a workpiece during use, the outlet passage having one or more walls; and a detector arranged to detect whether a fastener is present in the outlet passage. The detector comprises at least part of a cover that provides at least part of a wall of the outlet passage, the cover being movable with respect to the remainder of the outlet passage to open the outlet passage and gain access thereto.

Abstract: A fastener driving tool arranged to drive fasteners into a workpiece includes a support, a pair of sub-assemblies movably mounted on the support, each sub-assembly comprising a motor and an associated flywheel, and a nose part retractable relative to the support. The tool is arranged such that, in use, when the nose part is retracted, its movement relative to the support mechanically forces the sub-assemblies toward each other. The forcing of the sub-assemblies toward each other by the retraction of the nose part may move the sub-assemblies from an inoperative position to an operative position.

Abstract: A fastener driving tool arranged to drive fasteners into a workpiece includes a support, at least one wheel movably mounted on the support, a driver arranged to contact and he guided by the wheel when the wheel is in an operative position in use, a nose part retractable relative to the support, and a connection mechanism to operatively interconnect the nose part with the wheel. The tool is arranged such that, in use, the retraction of the nose part causes the connection mechanism to move the wheel from an inoperative position to the operative position. Subsequent forward movement of the driver guided by the wheel toward the nose part causes the operative interconnection between the nose part and the wheel to be broken. Forward movement of the nose part relative to the support, subsequent to the operative interconnection between the nose part and the wheel being broken, causes the operative interconnection between the nose part and the wheel to be re-formed.

Abstract: A fastener driving tool arranged to drive fasteners into a workpiece includes at least one electric motor having a central stator and an external rotor arranged to rotate around the stator. The rotor may be in the form of a flywheel. The tool includes an energy transfer member such as a driver arranged to transfer kinetic energy from the rotor to a fastener held in the tool, thereby to drive the fastener from the tool into a workpiece. The electric motor may be a brushless motor. The tool may include two such motors, arranged such that both of their rotors propel the driver simultaneously.

Abstract: A fastener supply assembly for a fastener driving tool includes an outlet passage arranged to expel fasteners from the assembly to a workpiece during use, a magazine comprising a plurality of supply channels arranged to hold fasteners and supply them to the outlet passage, and a channel selector. The channel select has an opening and is arranged to selectively connect, via its opening, the outlet passage with each respective supply channel of the magazine, by movement of the channel selector relative to both the magazine and a longitudinal axis of the outlet passage. The movement of the channel selector may comprise rotation about the longitudinal axis of the outlet passage.

Abstract: A hand held motor driven electrically powered tool, in particular a rotary hammer, comprising a spindle (40) for rotatingly driving a tool or bit (68), a spindle rotary drive train (14, 5, 10) for rotatingly driving the spindle (40) and an arrangement for detecting blocking events (16, 17). Blocking events occur when the tool or bit of the tool become rotationally fixed in the material being bored in which case the rotary drive on the spindle from the motor causes the tool housing to rotate in a user's grip.

Abstract: A battery protection and monitoring system includes a plurality of MAFET (Mechanically Actuated Field Effect Transistor) switches, wherein each MAFET switch among the MAFET switches is capable of switching from an open switch condition to a closed switch condition or vice versa, such that the plurality of MAFET switches are connectable to a battery. Such a system further includes one or more transistors associated with and which communicate electrically with at least one MAFET switch among the MAFET switches. A PPTC (Polymeric Positive Temperature Coefficient) device is also associated with the transistors and the MAFET switches, such that the PPTC device, the MAFET switches and the transistors operate in association with one another and the open switch condition or the closed switch condition of the plurality of MAFET switches to identify, monitor and thus prevent at least one dangerous condition associated with the battery.

Abstract: Techniques and processes for subsidizing network access via content and advertising revenue are described. In one implementation, a user installs a context bar tool on the user's computing device. To access a network (e.g., a wireless network), the user activates the context bar tool and requests access to a network, such as the Internet. A network services provider detects the context bar tool and provides network access to the user. A content and ads service gathers content and advertising and populates a context bar graphic interface that is displayed on the user's device with the content and advertising. Providers of the content and advertising pay for this exposure and thus generate revenue that can be used to offset the cost of providing the network access and other network services.

Abstract: The present invention provides a process and a device for regeneration of a nitrogen oxide storage catalyst in the exhaust system of a diesel engine. The process comprises a first and a second regeneration strategy. The first regeneration strategy is applied when the exhaust gas temperature is above a threshold value and comprises changing the air/fuel-ratio from a lean to a rich value during a first regeneration period. The second regeneration strategy is applied when the exhaust gas temperature is below a threshold value and comprises switching the air/fuel-ratio back and forth between lean and rich air/fuel-ratios, forming a sequence of between 2 and 10 rich pulses and between 2 and 10 lean pulses during a second regeneration period.

Abstract: Web service management techniques involving a portal are described. In an implementation, a method includes providing a portal, through which, web services are accessible to a client. Access to the web services is managed such that when the client is not associated with a current subscription to a provider of the portal, access is limited to the web services specified by a list.

Abstract: Many Gram-negative pathogens assemble adhesive pili structures on their surfaces that allow them to colonize host tissues and cause disease. The present invention relates to novel compounds that mimic a chaperone G1 beta-strand or an amino terminal motif of a pilus subunit. The present invention also relates to the complex formed from the binding of such mimic compounds to the hydrophobic groove of a pilus subunit. Competitively interacting with the binding site of pili subunits will negatively affect the chaperone/usher pathway, which is one molecular mechanism by which Gram-negative bacteria assemble adhesive pili structures, and thus prevent or inhibit pilus assembly.

Abstract: Apparatus for the production of extruded blown cellulose film from a solution of cellulose, water and an amine-oxide, which includes:—extrusion apparatus for continuously extruding a cellulose solution to produce a cellulose film;—solidifying apparatus for solidifying the extruded cellulose film;—drawing apparatus positioned downstream of the extrusion apparatus for continuously drawing the extruded cellulose film from the extrusion apparatus; and a tubular member for containing precipitation apparatus and for receiving an extruded blown film wherein the tubular member is situated within a precipitation bath. The invention also includes a method of extruding blown film.

Abstract: A hand held electrically powered hammer comprises a housing, a motor, and a hollow spindle. A piston and a ram are located for reciprocation within the spindle. A casing encloses at least part of the spindle so as to define a chamber between the spindle and the casing. A damping mass is slideably supported by a spacer and is located within the chamber and is connected to the hammer housing via a spring so as to oscillate back and forth along the spindle to minimize the vibration of the hammer housing and also so as to generate air flows within the chamber for facilitating heat transfer from the spindle to the metal casing.

Abstract: The present invention provides a process and a device for regeneration of a nitrogen oxide storage catalyst in the exhaust system of a diesel engine. The process comprises a first and a second regeneration strategy. The first regeneration strategy is applied when the exhaust gas temperature is above a threshold value and comprises changing the air/fuel-ratio from a lean to a rich value during a first regeneration period. The second regeneration strategy is applied when the exhaust gas temperature is below a threshold value and comprises switching the air/fuel-ratio back and forth between lean and rich air/fuel-ratios, forming a sequence of between 2 and 10 rich pulses and between 2 and 10 lean pulses during a second regeneration period.