Abstract: A method for operating a scanning acoustic microscope. The method including: scanning a sample in an X-Y plane by a transducer unit having one or more transducers. Wherein the scanning includes: moving the transducer unit in the X direction for a linear scanning of the sample; after the linear scanning of the sample by the transducer unit, displacing the transducer unit in the Y direction by a displacement increment; and varying a size of the displacement increment of the transducer unit in the Y direction for the scanning of the sample.

Abstract: The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject.

Abstract: Provided herein are methods of preparing a poloxamer for use in a cell culture medium. Also provided herein are cell culture media containing the poloxamer prepared by the methods herein, as well as methods of using the media for cell culturing and polypeptide production from cells.

Abstract: An apparatus for fastening lines, in particular power cables, pipes or hoses, includes at least two interconnectible fastening parts which form a feedthrough when assembled. The fastening parts include two clamp parts which are hinged together via at least one hinge and which each receive at least one clamping block having a groove in its outer lateral surface, in which groove a portion of a clamp part is positioned, and which clamping block has, on its inner face opposite the groove, a channel, which has the shape of a cylinder-barrel portion and extends axially at a right angle to the groove, for receiving a line. A fastener is arranged at the end of a clamp part opposite the hinged connection, the fastener hook of which fastener can be brought into engagement with a mating fastener hook arranged at the end of the other clamp part opposite the hinged connection.

Abstract: A coupling part for a hose coupling, in particular for high-pressure hydraulic lines, and a hose coupling having such coupling part, has a connection head for connecting to a fitting, and, formed on the connection head, a press-fit nipple, which is intended for accommodating a hose-end portion, on which a pushed-on hose-end portion can be fastened in a sealing manner by pressing action by an at least partially sleeve-form press-fit ferrule enclosing the hose-end portion, and which has a rib profile including ribs bounded by grooves. The rib profile has at least two profile portions. The grooves of the first profile portion, which is directed towards the connection head, have a symmetrical cross section and the grooves of the second profile portion have an asymmetrical cross section and a larger groove volume than the grooves of the first profile portion.

Abstract: The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject.

Abstract: A cutting ring fitting for a thin-walled pipe, includes: a connecting body having a tapered cone; a cutting ring; a union nut which can be screwed onto the connecting body; and a reinforcing sleeve for insertion into the pipe, the reinforcing sleeve having an axial slot. A pipe includes such a cutting ring fitting, and a method mounts such a cutting ring fitting on a thin-walled pipe.

Abstract: An apparatus for fastening lines, in particular power cables, pipes or hoses, includes at least two interconnectible fastening parts which form a feedthrough when assembled. The fastening parts include two clamp parts which are hinged together via at least one hinge and which each receive at least one clamping block having a groove in its outer lateral surface, in which groove a portion of a clamp part is positioned, and which clamping block has, on its inner face opposite the groove, a channel, which has the shape of a cylinder-barrel portion and extends axially at a right angle to the groove, for receiving a line. A fastener is arranged at the end of a clamp part opposite the hinged connection, the fastener hook of which fastener can be brought into engagement with a mating fastener hook arranged at the end of the other clamp part opposite the hinged connection.

Abstract: A coupling part for a hose coupling, in particular for high-pressure hydraulic lines, and a hose coupling having such coupling part, has a connection head for connecting to a fitting, and, formed on the connection head, a press-fit nipple, which is intended for accommodating a hose-end portion, on which a pushed-on hose-end portion can be fastened in a sealing manner by pressing action by an at least partially sleeve-form press-fit ferrule enclosing the hose-end portion, and which has a rib profile including ribs bounded by grooves. The rib profile has at least two profile portions. The grooves of the first profile portion, which is directed towards the connection head, have a symmetrical cross section and the grooves of the second profile portion have an asymmetrical cross section and a larger groove volume than the grooves of the first profile portion.

Abstract: The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject.

Abstract: Provided herein are methods of preparing a poloxamer for use in a cell culture medium. Also provided herein are cell culture media containing the poloxamer prepared by the methods herein, as well as methods of using the media for cell culturing and polypeptide production from cells.

Abstract: The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject.

Abstract: A cutting ring fitting for a thin-walled pipe, includes: a connecting body having a tapered cone; a cutting ring; a union nut which can be screwed onto the connecting body; and a reinforcing sleeve for insertion into the pipe, the reinforcing sleeve having an axial slot. A pipe includes such a cutting ring fitting, and a method mounts such a cutting ring fitting on a thin-walled pipe.

Abstract: A device for fastening hoses includes two fastening parts which can be connected to one another and which, in the assembled state, form a passage having an elliptical, in particular circular cross-section, wherein at least one radially encircling groove having an in particular edge-free cross-section is arranged in the inner lateral surface of the passage.

Abstract: Provided herein are methods of preparing a poloxamer for use in a cell culture medium. Also provided herein are cell culture media containing the poloxamer prepared by the methods herein, as well as methods of using the media for cell culturing and polypeptide production from cells.

Abstract: A connection arrangement for connecting a metallic pipeline has a screw connection body having a pipe holder for the pipeline, a union nut that can be screwed onto the screw connection body and a cutting ring disposed between the screw connection body and the union nut. The cutting ring has an outer cone that interacts with an inner cone of the pipe holder of the screw connection body. The cutting ring has an essentially radial contact surface, subsequent to the outer cone, which surface limits tightening against a face surface of the screw connection body. An elastomer circumferential seal is disposed in a ring groove in the region of the outer cone of the cutting ring. The ring groove, which accommodates the elastomer circumferential seal, is disposed in the outer cone of the cutting ring, at a distance from its contact surface and, wherein a ring surface is formed between the ring groove and the contact surface.

Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.

Abstract: A device for fixing components, particularly pipes or tubes, includes two fixing parts with recesses, which can be connected to each other, the parts forming a bushing in the mounted state, the inner contour thereof being designed to receive a pipe or a tube, at least one sacrificial element being arranged for minimizing corrosion, particularly crevice corrosion, in the event of a respectively received component being increasingly consumed with the onset of corrosion and reduction of the service life of the fixation. At least one fixing part includes at least one recess which opens up into the inner contour of the bushing and in which at least one sacrificial element is movably arranged, the sacrificial element being pre-stressed in the direction of the bushing by a spring element.

Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.

Abstract: The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject.