Abstract: Oligonucleotide primers and probes for quantifying and/or detecting human male DNA in a forensic sample. The oligonucleotides are useful for amplifying a multicopy locus within the human Y-chromosome (MCL-Y) that shares at least 80% sequence identity to a sequence according to SEQ ID NO. 3 over a stretch of at least 60 base pairs. The oligonucleotides hybridize under stringent conditions to a nucleic acid having at least one sequence selected from the group consisting of SEQ ID NO. 3 to SEQ ID NO. 11 and/or SEQ ID NO. 17 to SEQ ID NO. 25. Kits including the oligonucleotide primers, probes and/or primer pairs and reagents for performing an amplification reaction on DNA recovered from a forensic sample are also disclosed.

Abstract: Provided herein are methods of preparing a poloxamer for use in a cell culture medium. Also provided herein are cell culture media containing the poloxamer prepared by the methods herein, as well as methods of using the media for cell culturing and polypeptide production from cells.

Abstract: An apparatus for fastening lines, in particular power cables, pipes or hoses, includes at least two interconnectible fastening parts which form a feedthrough when assembled. The fastening parts include two clamp parts which are hinged together via at least one hinge and which each receive at least one clamping block having a groove in its outer lateral surface, in which groove a portion of a clamp part is positioned, and which clamping block has, on its inner face opposite the groove, a channel, which has the shape of a cylinder-barrel portion and extends axially at a right angle to the groove, for receiving a line. A fastener is arranged at the end of a clamp part opposite the hinged connection, the fastener hook of which fastener can be brought into engagement with a mating fastener hook arranged at the end of the other clamp part opposite the hinged connection.

Abstract: A coupling part for a hose coupling, in particular for high-pressure hydraulic lines, and a hose coupling having such coupling part, has a connection head for connecting to a fitting, and, formed on the connection head, a press-fit nipple, which is intended for accommodating a hose-end portion, on which a pushed-on hose-end portion can be fastened in a sealing manner by pressing action by an at least partially sleeve-form press-fit ferrule enclosing the hose-end portion, and which has a rib profile including ribs bounded by grooves. The rib profile has at least two profile portions. The grooves of the first profile portion, which is directed towards the connection head, have a symmetrical cross section and the grooves of the second profile portion have an asymmetrical cross section and a larger groove volume than the grooves of the first profile portion.

Abstract: The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject.

Abstract: A cutting ring fitting for a thin-walled pipe, includes: a connecting body having a tapered cone; a cutting ring; a union nut which can be screwed onto the connecting body; and a reinforcing sleeve for insertion into the pipe, the reinforcing sleeve having an axial slot. A pipe includes such a cutting ring fitting, and a method mounts such a cutting ring fitting on a thin-walled pipe.

Abstract: An apparatus for fastening lines, in particular power cables, pipes or hoses, includes at least two interconnectible fastening parts which form a feedthrough when assembled. The fastening parts include two clamp parts which are hinged together via at least one hinge and which each receive at least one clamping block having a groove in its outer lateral surface, in which groove a portion of a clamp part is positioned, and which clamping block has, on its inner face opposite the groove, a channel, which has the shape of a cylinder-barrel portion and extends axially at a right angle to the groove, for receiving a line. A fastener is arranged at the end of a clamp part opposite the hinged connection, the fastener hook of which fastener can be brought into engagement with a mating fastener hook arranged at the end of the other clamp part opposite the hinged connection.

Abstract: A coupling part for a hose coupling, in particular for high-pressure hydraulic lines, and a hose coupling having such coupling part, has a connection head for connecting to a fitting, and, formed on the connection head, a press-fit nipple, which is intended for accommodating a hose-end portion, on which a pushed-on hose-end portion can be fastened in a sealing manner by pressing action by an at least partially sleeve-form press-fit ferrule enclosing the hose-end portion, and which has a rib profile including ribs bounded by grooves. The rib profile has at least two profile portions. The grooves of the first profile portion, which is directed towards the connection head, have a symmetrical cross section and the grooves of the second profile portion have an asymmetrical cross section and a larger groove volume than the grooves of the first profile portion.

Abstract: An acceleration sensor (100) has a sensor mass (120) which is movably mounted over a substrate (120) by means of spring elements (130), so as to move along a movement axis (x), first trim electrodes (140), which are connected to the sensor mass (120), and sensor electrodes (160), which are connected to the sensor mass (120). The acceleration sensor (100) has, in addition, second trim electrodes (150), which are connected to the substrate (110) and associated with the first trim electrodes (140), and detection electrodes (170), which are connected to the substrate (110) and associated with the sensor electrodes (160). The sensor electrodes (160) and the detection electrodes (170) are suitable for deflecting the sensor mass (120) along the movement axis (x) and for measuring a first electrostatic force that is exerted on the sensor mass (120) by the sensor electrodes (160) and the detection electrodes (170).

Abstract: Apparatus and methods for recovering watercraft. A ramp is movable relative to a stationary carrying apparatus between a recovering position and a parked position. The ramp includes a frame and a deformable body, which is fastened to the frame. When the ramp is in the recovering position, the deformable body points toward the watercraft to be recovered and is located at least partially above the water surface. The watercraft travels onto the ramp and deforms the deformable body from above. The watercraft is pulled out of the water and moved onto the carrying apparatus.

Abstract: The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject.

Abstract: Provided herein are methods of preparing a poloxamer for use in a cell culture medium. Also provided herein are cell culture media containing the poloxamer prepared by the methods herein, as well as methods of using the media for cell culturing and polypeptide production from cells.

Abstract: The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject.

Abstract: A cutting ring fitting for a thin-walled pipe, includes: a connecting body having a tapered cone; a cutting ring; a union nut which can be screwed onto the connecting body; and a reinforcing sleeve for insertion into the pipe, the reinforcing sleeve having an axial slot. A pipe includes such a cutting ring fitting, and a method mounts such a cutting ring fitting on a thin-walled pipe.

Abstract: A device for fastening hoses includes two fastening parts which can be connected to one another and which, in the assembled state, form a passage having an elliptical, in particular circular cross-section, wherein at least one radially encircling groove having an in particular edge-free cross-section is arranged in the inner lateral surface of the passage.

Abstract: Provided herein are methods of preparing a poloxamer for use in a cell culture medium. Also provided herein are cell culture media containing the poloxamer prepared by the methods herein, as well as methods of using the media for cell culturing and polypeptide production from cells.

Abstract: A connection arrangement for connecting a metallic pipeline has a screw connection body having a pipe holder for the pipeline, a union nut that can be screwed onto the screw connection body and a cutting ring disposed between the screw connection body and the union nut. The cutting ring has an outer cone that interacts with an inner cone of the pipe holder of the screw connection body. The cutting ring has an essentially radial contact surface, subsequent to the outer cone, which surface limits tightening against a face surface of the screw connection body. An elastomer circumferential seal is disposed in a ring groove in the region of the outer cone of the cutting ring. The ring groove, which accommodates the elastomer circumferential seal, is disposed in the outer cone of the cutting ring, at a distance from its contact surface and, wherein a ring surface is formed between the ring groove and the contact surface.

Abstract: Apparatus and methods for recovering watercraft. A ramp is movable relative to a stationary carrying apparatus between a recovering position and a parked position. The ramp includes a frame and a deformable body, which is fastened to the frame. When the ramp is in the recovering position, the deformable body points toward the watercraft to be recovered and is located at least partially above the water surface. The watercraft travels onto the ramp and deforms the deformable body from above. The watercraft is pulled out of the water and moved onto the carrying apparatus.

Abstract: Processes are described for the preparation of F-benzoxazinorifamycin I: and intermediates for conjugation with an antibody.

Abstract: A device for fixing components, particularly pipes or tubes, includes two fixing parts with recesses, which can be connected to each other, the parts forming a bushing in the mounted state, the inner contour thereof being designed to receive a pipe or a tube, at least one sacrificial element being arranged for minimizing corrosion, particularly crevice corrosion, in the event of a respectively received component being increasingly consumed with the onset of corrosion and reduction of the service life of the fixation. At least one fixing part includes at least one recess which opens up into the inner contour of the bushing and in which at least one sacrificial element is movably arranged, the sacrificial element being pre-stressed in the direction of the bushing by a spring element.