Abstract: The invention relates to a device (10) for closing pharmaceutical containers (12) by means of closures (14).

Abstract: A system includes a container and a security label. The container is divisible into a plurality of parts and has a container body and a removable container closure. The security label has a first label section and a second label section forming respective parts of a common material web and a severing element which is arranged between the first and second label section with respect to a longitudinal axis of the security label. The security label is applied to the container such that the first label section is attached to the container body and the second label section surrounds the container closure. The second label section is formed such that the security label is closed along an edge line above the container closure by gluing and/or welding such that the second label section encloses the removable container closure.

Abstract: The invention relates to a system (10) for transporting loose sterile closure elements (12) from the surroundings (14) of an isolator (16) into an interior (18) of the isolator, comprising a container (24) for storing a stock quantity of closure elements in the h surroundings of the isolator, an isolator opening (20) and a collecting device (56) for collecting the closure elements and for providing the closure elements in the interior of the isolator, with a metering device (46) for controlling a target quantity of closure elements to be transported from the container through the isolator opening and into the collecting device.

Abstract: The present invention relates to compounds of formula (I), tautomers, stereoisomers, pharmaceutically acceptable salts and pro-drugs thereof, to processes for their preparation, to pharmaceutical compositions containing such compounds and to their use in therapy wherein a dashed line indicates an optional bond; X represents: a 5- or 6-membered, unsaturated heterocyclic group optionally substituted by one or more (e.g. 1, 2 or 3) substituents independently selected from halogen (i.e. F, Cl, Br, I), C1-6 alkyl (e.g. C1-3 alkyl), C1-6 haloalkyl (e.g. C1-3 haloalkyl), C1-6 alkoxy (e.g. C1-3 alkoxy), —CN, —NO2, —N(R)2, and —SO2R (where each R is independently H or C1-6 alkyl, e.g. H or C1-3 alkyl); a C3-5 cycloalkyl group optionally substituted by one or more (e.g. 1 or 2) substituents independently selected from C1-6 alkyl (preferably C1-3 alkyl), C1-6 haloalkyl (e.g. C1-3 haloalkyl), and C1-6 alkoxy (e.g. C1-3 alkoxy); or an aryl group optionally substituted by one or more (e.g.

Abstract: An electronic labelling assembly for a multi-part container includes a sleeve-shaped supplementary element which includes a coupling structure and which is configured to be coupled with respect to a longitudinal axis of the supplementary element by the coupling structure to an outer surface of a primary closure of the container and to surround the primary closure. The labelling assembly further includes an RFID functional unit having an RFID chip and an antenna structure coupled thereto. The supplementary element and the RFID functional unit are formed in coordination with each other and coupled to each other so that the RFID functional unit is attachable to the primary closure of the container by the supplementary element.

Abstract: The present invention relates to compounds of general formula (I), tautomers, stereoisomers, N-oxides, pharmaceutically acceptable salts and pro-drug thereof, to processes for their preparation, to pharmaceutical compositions containing such compounds and to their use in therapy: wherein: a dashed line indicates an optional bond; X represents: a 5- or 6-membered, unsaturated heterocyclic group optionally substituted by one or more (e.g. 1, 2 or 3) substituents independently selected from halogen (i.e. F, Cl, Br, I), C1-6 alkyl (e.g. C1-3 alkyl), C1-6 haloalkyl (e.g. C1-3 haloalkyl), C1-6 alkoxy (e.g. C1-3 alkoxy), —CN, —NO2, —N(R)2, and —SO2R (where each R is independently H or C1-6 alkyl, e.g. H or C1-3 alkyl); a C3-5 cycloalkyl group optionally substituted by one or more (e.g. 1 or 2) substituents independently selected from C1-6 alkyl (preferably C1-3 alkyl), C1-6 haloalkyl (e.g. C1-3 haloalkyl), and C1-6 alkoxy (e.g. C1-3 alkoxy); or an aryl group optionally substituted by one or more (e.g.

Abstract: An adhesive label for a multi-part container having a threaded member and a container body includes a first, sheet-like label portion adapted to be attached to the threaded member of the container, and a second label portion adjacent the first label portion and adapted to be attached to the container body of the container. The second label portion has a comb-like structure with strip-shaped fixing elements such that the adhesive label couples the threaded member to the container body relative to a condition applied to the container and opposes movement of the threaded member relative to the container body.

Abstract: A labeling arrangement (1) for frozen applications comprises a top label (10) having an adhesive layer (12) having a predetermined freezing temperature below 0° C. The labeling arrangement (1) further comprises a base component (20) having a base layer (21) and an interlocking structure (22) comprising a plurality of hook-shaped coupling elements (23). The hook-shaped coupling elements (23) each comprise a first and a second portion (231, 232) which are geometrically different such that the first portion (231) extends laterally beyond the second portion (232) with respect to a main lateral extension plane of the base layer (21), the second portion (232) being arranged between the first portion (231) and the base layer (21) and coupling the first portion (231) to the base layer (21).

Abstract: An adhesive label for a multi-part container having a threaded member and a container body includes a first, sheet-like label portion adapted to be attached to the threaded member of the container, and a second label portion adjacent the first label portion and adapted to be attached to the container body of the container. The second label portion has a comb-like structure with strip-shaped fixing elements such that the adhesive label couples the threaded member to the container body relative to a condition applied to the container and opposes movement of the threaded member relative to the container body.

Abstract: An adhesive label for a multi-part container having a threaded member and a container body includes a first, sheet-like label portion adapted to be attached to the threaded member of the container, and a second label portion adjacent the first label portion and adapted to be attached to the container body of the container. The second label portion has a comb-like structure with strip-shaped fixing elements such that the adhesive label couples the threaded member to the container body relative to a condition applied to the container and opposes movement of the threaded member relative to the container body.

Abstract: A protective cap for attachment to a needle stick protection device (20) for a syringe includes a sleeve-shaped cap body configured to enclose a needle guard of the syringe. The protective cap further includes at least one coupling member coupled to the cap body and configured to couple the cap body to an outer housing of the needle stick protection device and to secure the protective cap to the needle stick protection device.

Abstract: A labelling arrangement for a multi-part container includes a sleeve-shaped cap element having an interlocking structure adapted to be applied to a first part of the container and coupled to the first part by the interlocking structure. The labelling arrangement further includes a sealing label adapted to be attached to a second part of the container by a second label portion and to surround the applied cap element by a first label portion. The labelling arrangement further includes at least one severing region so that, when the container applied with the labelling arrangement is opened, the labelling arrangement is severable in the severing region and at least a part of the cap element is removable together with the first part of the container from the second part of the container.

Abstract: A labeling arrangement (1) for frozen applications comprises a top label (10) having an adhesive layer (12) having a predetermined freezing temperature below 0° C. The labeling arrangement (1) further comprises a base component (20) having a base layer (21) and an interlocking structure (22) comprising a plurality of hook-shaped coupling elements (23). The hook-shaped coupling elements (23) each comprise a first and a second portion (231, 232) which are geometrically different such that the first portion (231) extends laterally beyond the second portion (232) with respect to a main lateral extension plane of the base layer (21), the second portion (232) being arranged between the first portion (231) and the base layer (21) and coupling the first portion (231) to the base layer (21).

Abstract: A security label for a multi-part container includes a first section for attachment to a first container part and a second section adapted to a second container part with respect to a state of the label in that it is applied to the container, so that the label is closed in on itself along an edge line at a free end of the second section facing away from the first section. The two sections form a respective mutually adjacent part of a common material web. The label further includes a severing element between the first and second sections relative to a label longitudinal axis, so that, when the container applied with the label is opened, the label can be cut in a predetermined manner by the severing element and the second section can be removed together with the second container part from the first section and the first container part.

Abstract: The present invention relates to compounds of formula (I), tautomers, stereoisomers, pharmaceutically acceptable salts and pro-drugs thereof, to processes for their preparation, to pharmaceutical compositions containing such compounds and to their use in therapy wherein a dashed line indicates an optional bond; X represents: a 5- or 6-membered, unsaturated heterocyclic group optionally substituted by one or more (e.g. 1, 2 or 3) substituents independently selected from halogen (i.e. F, Cl, Br, I), C1-6 alkyl (e.g. C1-3 alkyl), C1-6 haloalkyl (e.g. C1-3 haloalkyl), C1-6 alkoxy (e.g. C1-3 alkoxy), —CN, —NO2, —N(R)2, and —SO2R (where each R is independently H or C1-6 alkyl, e.g. H or C1-3 alkyl); a C3-5 cycloalkyl group optionally substituted by one or more (e.g. 1 or 2) substituents independently selected from C1-6 alkyl (preferably C1-3 alkyl), C1-6 haloalkyl (e.g. C1-3 haloalkyl), and C1-6 alkoxy (e.g. C1-3 alkoxy); or an aryl group optionally substituted by one or more (e.g.

Abstract: A label for a medication container that is in multiple parts or can be divided into multiple parts has a first label section, to be attached to a first container part, and a second label section, to be attached to a second container part. The first label part serves for being wrapped completely around the first container part, more than once, and is disposed within a first basic surface area region of the basic surface area of the label, intended to be wrapped around the first container part. The second label section includes a spare label having a first sub-section and a second sub-section. The first sub-section is disposed in the first basic surface area region, and the second sub-section is disposed in a second basic surface area region, which is intended for being attached to a second container part.

Abstract: A method produces a casting, in particular a housing of a turbocharger, wherein at least one mold part for forming the casting has a respective parting plane which is arranged at a predetermined angle with respect to the longitudinal axis of the casting, and wherein at least one core element is provided.

Abstract: A label for a medication container that is in multiple parts or can be divided into multiple parts has a first label section, to be attached to a first container part, and a second label section, to be attached to a second container part. The first label part serves for being wrapped completely around the first container part, more than once, and is disposed within a first basic surface area region of the basic surface area of the label, intended to be wrapped around the first container part. The second label section includes a spare label having a first sub-section and a second sub-section. The first sub-section is disposed in the first basic surface area region, and the second sub-section is disposed in a second basic surface area region, which is intended for being attached to a second container part.

Abstract: The present invention relates to compounds of formula I, to processes for their preparation, to pharmaceutical formulations containing such compounds and to their use in therapy: Such compounds find particular use in the treatment and/or prevention of conditions or diseases which are affected by over-activation of signaling in the Wnt pathway and increased presence of nuclear ?-catenin. For example, these may be used in preventing and/or retarding proliferation of tumor cells and metastasis, for example carcinomas such as colon carcinomas.

Abstract: The present invention relates to compounds of formula I, to processes for their preparation, to pharmaceutical formulations containing such compounds and to their use in therapy: Such compounds find particular use in the treatment and/or prevention of conditions or diseases which are affected by over-activation of signaling in the Wnt pathway and increased presence of nuclear ?-catenin. For example, these may be used in preventing and/or retarding proliferation of tumor cells and metastasis, for example carcinomas such as colon carcinomas.