Abstract: A method of producing a tool insert which comprises a central metal portion having edge regions of superabrasive material bonded thereto and presenting cutting edges or points for the tool insert is disclosed. A body (50) having major surfaces on each of opposite sides thereof, each having spaced strips (64) of superabrasive material, typically abrasive compact such as PCBN or PCD, for example, separated by a metal region or regions, such as cemented carbide, is provided. Each superabrasive strip of one major surface is arranged in register with a superabrasive strip of the opposite major surface. Alternatively, each superabrasive strip extends from one major surface to the opposite major surface. The body is severed from one major surface to the opposite major surface along at least two sets of planes intersecting at or in the respective superabrasive strips to produce the tool insert.

Abstract: A process for manufacturing a decorative mainly isometric thermosetting laminate (1) comprising an isometric core (2), a primary surface layer (10) and optionally a secondary surface layer (20). 85 parts by weight of preferably organic particles are mixed with 15-85 parts by weight of a thermosetting resin such as phenol-formaldehyde resin, melamine-formaldehyde resin, urea-formaldehyde resin or mixtures thereof under powerful kneading in an extruder sot hat friction heat forms. The thermosetting resin is hereby bonded to or impregnating the particles. The particles possibly bonded to one another are parted whereby an agglomerate of resin and particles is formed. The particle/resin mixture is then dried to a water content of below 10%. The dried particle/resin mixture is then evenly distributed and continuously or discontinuously compressed in one or more steps under heat and pressure so that the resin finally cures, whereby an isometric core (2) is formed.

Abstract: The invention provides methods and materials related to vaccines against self polypeptides. For example, the invention provides compositions containing chimeric IgE polypeptides and adjuvants.