Abstract: In described examples, an integrated circuit includes first and second current sources, first and second switches, a dV/dt phase detector, a control circuit, and source, gate, and drain terminals for coupling to, respectively, a source, gate, and drain of a power FET. The first switch is coupled between the first current source and the gate terminal. The second switch is coupled between the second current source and the gate terminal. The dV/dt phase detector detects a dV/dt phase of the power FET and outputs to the control circuit. The control circuit controls the first and second switches to perform a turn-on sequence of the power FET, including: closing the first switch while keeping the second switch open; and after receiving a signal from the dV/dt phase detector indicating the dV/dt phase has started, opening the first switch, and closing the second switch.

Abstract: Described herein is an oral sampling device, as well as methods of making and using the oral sampling device. The oral sampling device is configured to be placed inside of a human mouth to capture an analyte(s) found in bodily fluid, such as saliva, produced within the mouth. An example oral sampling device includes a body, at least a portion of which is sized to fit inside of a mouth of a human, has an outer surface, and a recess(es) defined in the outer surface to capture the analyte(s) therein. In some examples, a material of the body within the recess was subjected to a surface treatment to promote the capture of the analyte(s). In some examples, the oral sampling device includes a flavored substance disposed on at least the portion of the body that is to be received inside of a human mouth.

Abstract: A suction gripping device for picking up a plurality of substrates which are flat and flexible includes: a base body, which defines a plane; at least one gas suction vacuum module which is arranged on the base body and has at least one gas suction opening configured for withdrawing gas by suction and for generating a first vacuum so as to suction a respective one of the plurality of substrates against the suction gripping device; and at least one gas ejection vacuum module which is arranged on the base body and has a gas ejection opening configured for ejecting gas and for generating a second vacuum so as to suction the respective one of the plurality of substrates against the suction gripping device.

Abstract: A method of lining up portions of slices of food, the portions are transported by a belt conveyor on a plurality of tracks along a conveying direction, one of the plurality of tracks is selected as a first reference track, conveying speeds of a remainder of the plurality of tracks excluding the first reference track are adapted in such a way that the portions are arranged in straight rows arranged orthogonally to the conveying direction when the portions reach a lining-up position, and when the lining-up position is reached, the conveying speeds of the plurality of tracks including the first reference track are aligned to one another.

Abstract: A circuit includes a half-bridge circuit is configured to provide a switching voltage responsive to respective high-side and low-side drive signals. High-side slew control circuitry is configured to provide a high-side slew-compensated control signal responsive to a high-side enable signal and a slew current signal representative of a slew rate at a switching output. A high-side driver is configured to provide the high-side drive signal responsive to the high-side slew-compensated control signal. Low-side slew control circuitry is configured to provide a low-side slew-compensated drive signal responsive to a low-side enable signal and the slew current signal. A low-side driver is configured to provide the low-side drive signal responsive to the low-side slew-compensated control signal. A capacitor is coupled between the high-side and low-side slew control circuitry and is configured to convert the slew rate to the slew current signal.

Abstract: A system, template, and method of managing virtual control units in an industrial automation facility are provided. The industrial automation facility includes machines. The method includes generating templates including deployment criteria for the virtual control units. Each of the virtual control units is capable of controlling at least one of the machines. The virtual control units are mapped to one or more compute nodes based on the deployment criteria. The virtual control units are instantiated on the mapped compute nodes when the controlled machines are in operation. The method includes validating that the instantiation of the virtual control units is in accordance with the templates using an attestation that confirms determined deployment parameters after deployment of the virtual control units. The machines perform the industrial process, according to control commands received from at least one of the virtual control units, when the virtual control units are validly instantiated.

Abstract: The use of luteinizing hormone receptor (LHR) binding agents and luteinizing hormone (LH) agonists to enrich for primitive hematopoietic stem cell (pHSC) populations, to target pHSC for ablation, and/or to expand pHSC populations are described. The methods can be used to prepare therapeutic hematopoietic stem cell (HSC) populations, to prepare patients for therapeutic HSC transplants, and/or to treat malignancies, such as those associated with hyperproliferative HSC.

Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.

Abstract: A milling device for machining a slot into an inner surface of a casing for a gas turbine engine. The milling device includes a frame assembly including multiple structural guides configured to engage structural features on the inner surface of the casing to maintain an axial position of the milling device relative to a longitudinal axis of the casing. The milling device also includes a milling cutter coupled to the frame assembly. The milling device is configured to be displaced in a circumferential direction relative to the longitudinal axis to machine the slot, via the milling cutter, along the inner surface of the casing in the circumferential direction.

Abstract: The invention relates to substituted S-alaninate derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.

Abstract: A method for producing a boron emitter on at least one silicon wafer, arranged in a tube furnace, including: a step for forming borosilicate glass on the silicon wafer, including in the sequence given: a) evacuating the tube furnace to a specified pressure, b) feeding reagents, having BCU and O2, into the tube furnace and adjusting to a further specified pressure, c) stopping the supply after expiry of a specified period and allowing the reagents supplied to react with each other and a surface of the silicon wafer for a specified period to form a layer of borosilicate glass on the surface of the silicon wafer, and d) evacuating the tube furnace on expiry of the specified period.

Abstract: A connector connecting a line to a printed circuit board. The connector has a section of the line that has a first end, has a connection element that is joined to the end of the section of the line by a first end and is joined to a printed circuit board by a second end, has an insert part that receives the first end of the connection element and the end of the section of the line, the insert part has a recess through which the connection element projects or in which the first end of the connection element and the end of the section of the line are arranged, and has a cured casting compound that fills the recess so as to enclose the connection element or so as to enclose the first end of the connection element and the end joined thereto of the section of the line.

Abstract: A solar cell having a rear layer stack, wherein the rear layer stack has the following layer sequence: an AlOx layer, a first SiNx layer, a second SiNx layer, an SiOxNy layer, a third SiNx layer and at least one further layer, selected from the group consisting of SiOxNy, SiOx, AlOx, AINx and AlF. The invention further relates to a solar module comprising the solar cell, and a method of producing the solar cell, wherein the rear layer stack is deposited on a substrate in a tubular PECVD system with a boat as a substrate holder.

Abstract: A connector having a housing, having first contact elements and second contact elements that are connected to one another and arranged in the housing in order to establish an electrical connection, having first lines that are connected to the first contact elements, having second lines that are connected to the second contact elements or whose ends form the second contact elements, and having a casting resin that at least partially surrounds the contact elements, but surrounds at least the contact points between the first and the second contact elements The housing is formed of multiple parts, and has at least a first housing part and a second housing part that are connected to one another. The contact points are provided in or on the first housing part, and the casting resin has a connection to the first housing part.

Abstract: Fluidic devices and methods for autonomous droplet generation and methods for droplet manipulation are described. In an embodiment, the fluidic device comprises a substrate defining: an inlet reservoir shaped to receive and to carry a carrier liquid; a converging region in fluidic communication with the inlet reservoir and shaped to receive a liquid sample; a constriction adjacent to and in fluidic communication with the converging region, wherein the constriction defines a pathway configured to allow passage of fluid therethrough; a diverging region in fluidic communication with and downstream of the constriction; and an outlet reservoir in fluidic communication with the diverging region, wherein the fluidic device does not comprise a portion covering the outlet reservoir opposite the substrate.

Abstract: A sample vessel includes a biological sample container and a sample stabilizer container. The biological sample container is configured to receive a biological sample and to store the biological sample. The sample stabilizer container is configured to contain a stabilizer associated with the biological sample. The sample stabilizer container is assembled from a stabilizer vial, an adaptor, and a fluid channel. The stabilizer vial is configured to store an amount of the stabilizer. The adaptor is configured to secure the biological sample container and the stabilizer vial such that the biological sample container and the stabilizer vial form the sample vessel. The fluid channel extends through the adaptor from the stabilizer vial to the biological sample container, the biological sample moving from the biological sample container into the stabilizer vial through the fluid channel.

Abstract: The invention relates to PYY analogues having alanine at position 4, lysine at position 7, QRY as the C-terminal end and a half-life extending group. The analogues of the invention are soluble around pH 6 and 7. The invention also relates to pharmaceutical compositions comprising such PYY analogues, and to the medical use of the analogues.

Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.

Abstract: The present invention relates to difluoromethyl-pyridin-2-yl triazoles of general formula (I) which are modulators of GABAA receptors containing the ?5 subunit, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for the manufacture of compounds according to the invention.

Abstract: An apparatus includes: a first sensor configured to provide a first input; a second sensor configured to provide a second input; and a processing unit configured to receive the first input from the first sensor, and a second input from the second sensor; wherein the processing unit is configured to determine a first probability of a first predicted event, and a second probability of a second predicted event, wherein the first predicted event and the second predicted event are associated with an operation of the vehicle; and wherein the processing unit is configured to calculate a risk score based on the first probability of the first predicted event, and based on the second probability of the second predicted event.