Patents by Inventor STEFAN PRONIUK

STEFAN PRONIUK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MAKING ONAPRISTONE INTERMEDIATES
    Publication number: 20170088579
    Abstract: Methods and systems for making intermediates in the synthesis of onapristone are provided. Aspects include the photoconversion of onapristone synthesis intermediates using a narrow band frequency light source.
    Type: Application
    Filed: September 23, 2016
    Publication date: March 30, 2017
    Inventors: Ulf Tilstam, Stefan Proniuk, Holger Bindernagel, Silvia Werner, Holger Rauter
  • Drug delivery system to increase bioavailability
    Patent number: 9579387
    Abstract: A drug delivery system is presented to increase the bioavailability of biopharmaceutic class II, III, or IV active agents.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: February 28, 2017
    Assignee: ARNO THERAPEUTICS, INC.
    Inventors: Anh Thu Thi Pham, Akaash Kumari Singh, Stefan Proniuk
  • METHODS AND COMPOSITIONS FOR ENHANCED TRANSUNGUAL DELIVERY OF AR-12
    Publication number: 20170049748
    Abstract: Methods and compositions for enhancing transungual delivery of AR-12 comprising administering AR-12 and permeation enhancers are provided.
    Type: Application
    Filed: August 15, 2016
    Publication date: February 23, 2017
    Inventors: Sathyanarayana Narasimha Murthy, Stefan Proniuk
  • COMPOSITIONS AND METHODS FOR INHIBITING VIRAL INFECTION
    Publication number: 20160213647
    Abstract: Compositions and methods for inhibiting viral protein production, viral infection, and viral replication in a host or host cells infected with a virus (e.g., influenza, Junin, Chikungunya, Dengue, HIV, RHDV) by administering AR-12 and AR-12 analogs are provided.
    Type: Application
    Filed: January 27, 2016
    Publication date: July 28, 2016
    Inventors: Larry Schlesinger, Jacob Yount, Alexander Zukiwski, Stefan Proniuk, María Jesús Tuñón, Keivan Zandi
  • COMPOSITIONS AND METHODS FOR INHIBITING FUNGAL INFECTIONS
    Publication number: 20160199351
    Abstract: Compositions and methods for inhibiting fungal growth by administering AR-12 to a host infected with a fungus such as Histoplasma capsulatum, Aspergillus fumigatus, and Trichophyton rubrum, Paecilomyces, Rhizopus, Fusarium, Scedosporium, Lomentospora, Apophysomyces, Coccidioides, Blastomyces, non-albicans Candida, and Pneumocytis are provided.
    Type: Application
    Filed: January 7, 2016
    Publication date: July 14, 2016
    Inventors: Chad A. Rappleye, Alexander Zukiwski, Stefan Proniuk
  • ONAPRISTONE EXTENDED-RELEASE COMPOSITIONS AND METHODS
    Publication number: 20160166583
    Abstract: Onapristone extended-release formulations and methods of administering onapristone extended-release formulations are provided. Onapristone extended-release formulations provide sufficient therapeutic activity as compared to immediate-release formulations with reduced potential for adverse side effects.
    Type: Application
    Filed: November 16, 2015
    Publication date: June 16, 2016
    Inventors: Alexander Zukiwski, Stefan Proniuk
  • DRUG DELIVERY SYSTEM TO INCREASE BIOAVAILABILITY
    Publication number: 20160000923
    Abstract: Disclosed herein are novel methods of treating diseases, novel dosage forms, and novel methods of modulating the pharmacokinetics of active ingredients.
    Type: Application
    Filed: September 15, 2015
    Publication date: January 7, 2016
    Inventors: Anh Thu Thi Pham, Akaash Kumari Singh, Stefan Proniuk
  • Onapristone polymorphic forms and methods of use
    Patent number: 9193757
    Abstract: Polymorphic forms of onapristone and methods of making and using such polymorphic forms are provided. Crystalline polymorphic forms can be characterized by their X-ray powder diffraction patterns and other properties.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: November 24, 2015
    Assignee: ARNO THERAPEUTICS, INC.
    Inventor: Stefan Proniuk
  • Drug delivery system to increase bioavailability
    Patent number: 9138425
    Abstract: A drug delivery system is presented to increase the bioavailability of biopharmaceutic class II, III, or IV active agents.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: September 22, 2015
    Assignee: PATHEON INC.
    Inventors: Anh Thu Thi Pham, Akaash Kumari Singh, Stefan Proniuk
  • ONAPRISTONE POLYMORPHIC FORMS AND METHODS OF USE
    Publication number: 20150231155
    Abstract: Polymorphic forms of onapristone and methods of making and using such polymorphic forms are provided. Crystalline polymorphic forms can be characterized by their X-ray powder diffraction patterns and other properties.
    Type: Application
    Filed: March 18, 2015
    Publication date: August 20, 2015
    Inventor: Stefan Proniuk
  • HDAC Inhibitor Polymorphic Forms and Methods of Use
    Publication number: 20140271604
    Abstract: Polymorphic forms of histone deacetylase inhibitors (HDAC) and methods of making and using such polymorphic forms are provided. Crystalline polymorphic forms can be characterized by their X-ray powder diffraction patterns, solubility, stability and other properties.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Inventor: STEFAN PRONIUK
  • ONAPRISTONE POLYMORPHIC FORMS AND METHODS OF USE
    Publication number: 20140271819
    Abstract: Polymorphic forms of onapristone and methods of making and using such polymorphic forms are provided. Crystalline polymorphic forms can be characterized by their X-ray powder diffraction patterns and other properties.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Inventor: STEFAN PRONIUK
  • DRUG DELIVERY SYSTEM
    Publication number: 20140271872
    Abstract: Disclosed herein are novel methods of treating diseases, novel dosage forms, and novel methods of modulating the pharmacokinetics of active ingredients.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Applicant: Patheon Inc.
    Inventors: Anh Thu Thi Pham, Akaash Kumari Singh, Stefan Proniuk