Patents by Inventor Stefan Roland Woroniecki

Stefan Roland Woroniecki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of pharmaceutically active thiazolidine or oxazolidine compounds by a yeast reductase
    Publication number: 20040082041
    Abstract: 1
    Type: Application
    Filed: November 24, 2003
    Publication date: April 29, 2004
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Richard Mark Hindley, Stefan Roland Woroniecki
  • Clavulanic acid dehydrogenase, preparation and use for the production of clavulanic acid
    Patent number: 6692950
    Abstract: A compound of formula (I), wherein R=H or Na, or a salt thereof and an enzyme, obtainable from Streptomyces species, having clavulanic acid dehydrogenase activity which is capable of converting (I) into clavulanic acid.
    Type: Grant
    Filed: April 3, 1996
    Date of Patent: February 17, 2004
    Assignee: SmithKline Beecham plc
    Inventors: Stephen William Elson, Neville Hubert Nicholson, Stefan Roland Woroniecki, Janice Arnell
  • Clavulanic acid dehydrogenase, preparation and use for the production of clavulanic acid
    Publication number: 20030219867
    Abstract: An isolated DNA fragment encoding a protein with CAD activity wherein the protein is clavulanic acid dehydrogenase (CAD) from S. clavuligerus, with the proviso that the isolated DNA fragment is not: (a) the 13.1 kb BglII to SphI fragment of S. clavuligerus; (b) the 10.8 kb EcoRI to BamHI fragment of S. clavuligerus; (c) the 8.8 kb BclI to BclII fragment of S. clavuligerus; (d) the 2.5 kb BglII to BglII fragment of S. clavuligerus; (e) the 60 kb BglII to BamHI fragment of S. clavuligerus; or (f) the 18.0 BclI to SphI fragment of S. clavuligerus.
    Type: Application
    Filed: February 14, 2003
    Publication date: November 27, 2003
    Applicant: SmithKline Beecham plc
    Inventors: Janice Arnell, Stephen William Elson, Neville Hubert Nicholson, Stefan Roland Woroniecki
  • Process for the preparation of pharmaceutically active thiazolidine or oxazolidine compounds by a yeast reductase
    Publication number: 20020106762
    Abstract: 1
    Type: Application
    Filed: October 9, 2001
    Publication date: August 8, 2002
    Applicant: Smith Kline Beecham plc
    Inventors: Richard Mark Hindley, Stefan Roland Woroniecki
  • Process for the preparation of pharmaceutically active thiazolidine or oxazolidine compounds by a yeast reductase
    Publication number: 20020050563
    Abstract: 1
    Type: Application
    Filed: September 14, 2001
    Publication date: May 2, 2002
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Richard Mark Hindley, Stefan Roland Woroniecki
  • Process for the preparation of pharmaceutically active thiazolidine compounds by a yeast reductase
    Patent number: 5726055
    Abstract: A process for preparing 5-(4-?2-(N-methyl-N-(2-pyridyl)amino)-ethoxy!-benzyl)-2,4-thiazolidinedion e, by treating 5-(4-?2-(N-methyl-N-(2-pyridyl)amino)-ethoxy!benzylidene)-2,4-thiazolidine dione with a free whole yeast cell culture or immobilized whole yeast cells from Rhodotorula glutinis CBS 4406 or Rhodotorula rubra CBS 6469 as the microbial reductase source and recovering 5-(4-?2-N-methyl-(N-(2-pyridyl)amino)ethoxy!-benzyl)-2,4-thiazolidinedione , or a salt thereof.
    Type: Grant
    Filed: May 19, 1994
    Date of Patent: March 10, 1998
    Assignee: SmithKline Beecham plc
    Inventors: Richard Mark Hindley, Stefan Roland Woroniecki
  • Enzymatic preparation of monic acids
    Patent number: 5726049
    Abstract: A process for the production of monic acids which comprises contacting a corresponding pseudomonic acid or an ester thereof with a hydrolase enzyme from a suitable microorganism, in particular Streptomyces sp.
    Type: Grant
    Filed: February 15, 1996
    Date of Patent: March 10, 1998
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Esme Faith Hayes, John Thomas Sime, Stefan Roland Woroniecki, David Alan Yeandle