Patents by Inventor Stefan Scherer

Stefan Scherer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9691411
    Abstract: A method for assessing suicide risk for a human subject including receiving recorded voice data of the subject; and classifying the subject as suicidal or non-suicidal based upon a computerized analysis of one or more nonverbal characteristics of the speech data, especially features associated with a breathy phonation type. The analysis of the nonverbal characteristics of the voice data can include an analysis of acoustic characteristics of speech, and/or an analysis of prosodic and voice quality-related features of the voice data. Related apparatus, systems, techniques and articles are also described.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: June 27, 2017
    Assignees: CHILDREN'S HOSPITAL MEDICAL CENTER, UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Stefan Scherer, John P. Pestian, Louis-Philippe Morency
  • Publication number: 20170066822
    Abstract: The invention is concerned with a method of determining whether a patient is more suitably treated by a therapy with an angiogenesis inhibitor, such as bevacizumab, by determining the genotype of VEGFR-1 gene. The invention further relates to a pharmaceutical composition comprising an angiogenesis inhibitor, such as bevacizumab, for the treatment of a patient suffering from cancer based on the genotype of VEGFR-1 gene. The invention further relates to a method for improving the treatment effect of chemotherapy of a patient suffering from cancer by adding an angiogenesis inhibitor, such as bevacizumab, based on the genotype of VEGFR-1 gene.
    Type: Application
    Filed: November 17, 2016
    Publication date: March 9, 2017
    Inventors: Peter Carmeliet, Sanne Lysbet de Haas, Diether Lambrechts, Stefan Scherer
  • Publication number: 20160351888
    Abstract: Described is a coated, (partly) lithiated graphite powder characterized in that it has been produced in a non-electrochemical process from metallic lithium and graphite in powder form and has been stabilized outside an electrochemical cell by application of a coating layer; and a galvanic cell comprising a cathode, a lithium-conductive electrolyte-separator system and an anode comprising a coated, (partly) lithiated graphite powder, where the (partial) lithiation and the coating of the graphite powder are performed non-electrochemically outside the galvanic cell (ex situ).
    Type: Application
    Filed: February 13, 2015
    Publication date: December 1, 2016
    Inventors: Ulrich WIETELMANN, Vera NICKEL, Stefan SCHERER, Ute EMMEL, Thorsten BUHRMESTER, Steffen HABER, Gerd KRÄMER
  • Publication number: 20160351893
    Abstract: The invention relates to a galvanic cell containing a cathode, a lithium-conductive electrolyte separator system, and a synthetic graphite-containing anode. In the manufacture of the cell (i.e. prior to the first charging cycle), the anode contains or consists of a (partially) lithiated graphite powder which is produced from synthetic graphite and lithium powder in a non-electrochemical manner. The invention also relates to a method for (partially) lithiating synthetic graphite in an electroless manner. The invention is characterized in that the particulate synthetic graphite is (partially) lithiated in an electroless manner after mixing with particulate lithium metal powder and by means of a mixing and/or milling process, thereby forming Li graphite intercalates of the composition LiCx (mit x=6?600).
    Type: Application
    Filed: February 13, 2015
    Publication date: December 1, 2016
    Inventors: Ulrich Wietelmann, Vera Nickel, Stefan Scherer, Ute Emmel, Thorsten Buhrmester, Steffen Haber, Gerd Krämer
  • Patent number: 9451772
    Abstract: The present invention relates to a novel crystalline modification of fipronil, to a process for the preparation of the same, to pesticidal and parasiticidal mixtures and compositions comprising said crystalline modification and to their use for combating pests and parasites.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: September 27, 2016
    Assignee: BASF SE
    Inventors: Heidi Emilia Saxell, Peter Erk, Claude Taranta, Thomas Kroehl, Gerhard Cox, Martin Sukopp, Stefan Scherer, Antti Ojala, Gautam R. Desiraju, Rahul Banerjee, Prashant M. Bhatt
  • Patent number: 9353095
    Abstract: The present invention relates to a novel crystalline form A of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione. The invention also relates to a process for the production of this crystalline form and formulations for plant protection which contains the novel crystalline form of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: May 31, 2016
    Assignee: BASF SE
    Inventors: Robert Reinhard, Tiziana Chiodo, Bernd Wolf, Stefan Scherer, Matthias Bratz, Matthias Witschel, Trevor William Newton, Thomas Seitz
  • Patent number: 9328101
    Abstract: The present invention relates to a novel crystalline form B of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione The invention also relates to a process for the production of this crystalline form and formulations for plant protection which contains the novel crystalline form of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: May 3, 2016
    Assignee: BASF SE
    Inventors: Robert Reinhard, Tiziana Chiodo, Bernd Wolf, Stefan Scherer, Matthias Bratz, Matthias Witschel, Trevor William Newton, Thomas Seitz
  • Publication number: 20160111717
    Abstract: The present invention relates to methods for providing an active lithium reservoir to reduce the irreversible initial losses and as a general lithium source of or for electrode materials and lithium batteries, and a powdered lithium-donating material having an electrochemical potential of 0.5 and 2 V vs. Li/Li+, which has been selected from the group of lithium hydride, lithium amide, lithium imide and tetra-lithium ammonium hydride, is used as a general lithium source.
    Type: Application
    Filed: May 14, 2014
    Publication date: April 21, 2016
    Inventors: Ulrich Weitelmann, Ute Emmel, Stefan Scherer, Christoph Hartnig
  • Publication number: 20160099011
    Abstract: A method for assessing suicide risk for a human subject including receiving recorded voice data of the subject; and classifying the subject as suicidal or non-suicidal based upon a computerized analysis of one or more nonverbal characteristics of the speech data, especially features associated with a breathy phonation type. The analysis of the nonverbal characteristics of the voice data can include an analysis of acoustic characteristics of speech, and/or an analysis of prosodic and voice quality-related features of the voice data. Related apparatus, systems, techniques and articles are also described.
    Type: Application
    Filed: May 23, 2014
    Publication date: April 7, 2016
    Inventors: Stefan Scherer, John P. Pestian, Louis-Philippe Morency
  • Publication number: 20150352204
    Abstract: The present invention provides methods for improving the treatment effect of a chemotherapy regimen of a patient suffering from HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer, by adding bevacizumab (Avastin®) to a chemotherapy regimen by determining the expression level, in particular the blood plasma expression level, of E-selectin, ICAM-1 or VEGFR-3 relative to control levels of patients diagnosed with HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer.
    Type: Application
    Filed: December 19, 2014
    Publication date: December 10, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Ursula Klause, Nicola Moore, Celine Pallaud, Stefan Scherer, Norbert Wild
  • Patent number: 9161014
    Abstract: Method for compensating illumination deficiencies in microscopic “shape from focus (SFF)”, wherein firstly the reflectance of the scene is estimated by way of a projector-camera system and then microscopic “shape from focus (SFF)” is applied to a stack of reflectance maps rather than to the original image data.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: October 13, 2015
    Assignees: Alicona Imaging GmbH, Technische Universität Graz
    Inventors: Manfred Prantl, Stefan Scherer, Martin Lenz, Matthias Ruther, Horst Bischof
  • Patent number: 9051868
    Abstract: A method for monitoring a nitrogen oxide storage catalytic converter (NSC) in the exhaust gas duct of an internal combustion engine which is operated at least temporarily in a lean fashion, wherein during a lean mode of the internal combustion engine nitrogen oxides from the exhaust gas are stored by the nitrogen oxide storage catalytic converter, wherein during a regeneration phase of the nitrogen oxide storage catalytic converter the internal combustion engine is operated in a rich fashion, and as a result the nitrogen oxides stored in the nitrogen oxide storage catalytic converter are removed, and wherein an exhaust gas component or exhaust gas characteristic variable which is characteristic of the profile of the regeneration is detected during the regeneration phase by means of an exhaust gas probe.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: June 9, 2015
    Assignee: Robert Bosch GmbH
    Inventors: Stefan Scherer, Tobias Pfister, Herbert Schoemig, Holger Ziegler
  • Publication number: 20150141253
    Abstract: The present invention relates to a novel crystalline form B of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione The invention also relates to a process for the production of this crystalline form and formulations for plant protection which contains the novel crystalline form of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione.
    Type: Application
    Filed: May 15, 2013
    Publication date: May 21, 2015
    Inventors: Robert Reinhard, Tiziana Chiodo, Bernd Wolf, Stefan Scherer, Matthias Bratz, Matthias Witschel, Trevor William Newton, Thomas Seitz
  • Patent number: 9016049
    Abstract: A method is presented for controlling an internal combustion engine (10), which includes an exhaust gas system (12) having an exhaust gas aftertreatment component (22) that temporarily stores exhaust gas constituents and can be regenerated, wherein an expected value for a temperature of the exhaust gas aftertreatment component (22) is formed as a function of an increase in temperature, which arises as a result of exothermal reactions during the duration of an operating mode (BA2) of the internal combustion engine (10) which is set for the regeneration of said exhaust gas aftertreatment component (22), wherein the expected value is compared with an upper threshold value (T_max) and the control of said internal combustion engine (10) is changed when the threshold value (T_max) is exceeded, such that an expected value formed while taking the changed control into account does not exceed said threshold value (T_max).
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: April 28, 2015
    Assignee: Robert Bosch GmbH
    Inventors: Matthias Loehr, Stefan Scherer, Wolfram Faas, Rolf-Dieter Koch, Holger Ziegler
  • Publication number: 20150099631
    Abstract: The present invention relates to a novel crystalline form A of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione. The invention also relates to a process for the production of this crystalline form and formulations for plant protection which contains the novel crystalline form of 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione.
    Type: Application
    Filed: May 15, 2013
    Publication date: April 9, 2015
    Inventors: Robert Reinhard, Tiziana Chiodo, Bernd Wolf, Stefan Scherer, Matthias Bratz, Matthias Witschel, Trevor William Newton, Thomas Seitz
  • Publication number: 20150004136
    Abstract: The invention is concerned with a method of determining whether a patient is more suitably treated by a therapy with an angiogenesis inhibitor, such as bevacizumab, by determining the genotype of VEGFR-1 gene. The invention further relates to a pharmaceutical composition comprising an angiogenesis inhibitor, such as bevacizumab, for the treatment of a patient suffering from cancer based on the genotype of VEGFR-1 gene. The invention further relates to a method for improving the treatment effect of chemotherapy of a patient suffering from cancer by adding an angiogenesis inhibitor, such as bevacizumab, based on the genotype of VEGFR-1 gene.
    Type: Application
    Filed: May 22, 2014
    Publication date: January 1, 2015
    Applicants: Hoffmann-La Roche Inc., VIB vzw
    Inventors: Peter Carmeliet, Sanne Lysbet de Haas, Diether Lambrechts, Stefan Scherer
  • Publication number: 20140341893
    Abstract: The present invention provides methods for improving the treatment effect of a chemotherapy regimen of a patient suffering from HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer, by adding bevacizumab (Avastin®) to a chemotherapy regimen by determining the expression level, in particular the blood plasma expression level, of VEGFA and/or VEGFR2 relative to control levels of patients diagnosed with HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer. The present invention also provides for methods for assessing the sensitivity or responsiveness of a patient to bevacizumab (Avastin®) in combination with a chemotherapy regimen, by determining the expression level, in particular the blood plasma expression level, of VEGFA and/or VEGFR2 relative to control levels in patients diagnosed with HER2 positive breast cancer, in particular locally recurrent or metastatic HER2 positive breast cancer.
    Type: Application
    Filed: May 28, 2014
    Publication date: November 20, 2014
    Applicant: Genentech, Inc.
    Inventors: Herbert Andres, Sanne Lysbet de Haas, Rebecca Elliott, Johann Karl, Yu-Ju Gloria Meng, Gregory D. Plowman, Stefan Scherer, Norbert Wild
  • Publication number: 20140302019
    Abstract: The present invention provides methods for improving the treatment effect of a chemotherapy regimen of a patient suffering from pancreatic cancer, in particular metastatic pancreatic cancer by adding bevacizumab (Avastin®) to a chemotherapy regimen by determining the expression level, in particular the blood plasma expression level, of one or more of VEGFA, VEGFR2 and PLGF relative to control levels of patients diagnosed with pancreatic cancer, in particular metastatic pancreatic cancer. In particular, the present invention provides methods of improving the treatment effect, wherein the treatment effect is the overall survival and/or progression-free survival of the patient.
    Type: Application
    Filed: June 20, 2014
    Publication date: October 9, 2014
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Paul DELMAR, Dorothee FOERNZLER, Friedemann KRAUSE, Stefan SCHERER
  • Publication number: 20140294768
    Abstract: The invention is concerned with a method of determining whether a patient is more suitably treated by a therapy with an angiogenesis inhibitor, such as bevacizumab, by determining the genotype of VEGF promoter gene and/or VEGFR2 gene. The invention further relates to a pharmaceutical composition comprising an angiogenesis inhibitor, such as bevacizumab, for the treatment of a patient suffering from cancer based on the genotype of VEGF promoter gene and/or VEGFR2 gene. The invention further relates to a method for improving the treatment effect of chemotherapy of a patient suffering from cancer by adding an angiogenesis inhibitor, such as bevacizumab, based on the genotype of VEGF promoter gene and/or VEGFR2 gene.
    Type: Application
    Filed: February 26, 2014
    Publication date: October 2, 2014
    Inventors: Sanne Lysbet de Haas, Paul Delmar, Diether Lambrechts, Stefan Scherer
  • Publication number: 20140294811
    Abstract: The invention is concerned with a method of predicting a patient's susceptibility to developing hypertension associated with an anti-angiogenesis treatment, such as bevacizumab, by determining the genotype of KDR gene and/or EGF gene. The invention further relates to a pharmaceutical composition comprising an angiogenesis inhibitor, such as bevacizumab, for the treatment of a patient suffering from cancer based on the genotype of KDR gene and/or EGF. The invention further relates to a method for reducing the risk of hypertension associated with an anti-angiogenesis therapy, such as bevacizumab, in a patient suffering from cancer by determining the genotype of KDR gene and/or EGF gene.
    Type: Application
    Filed: February 26, 2014
    Publication date: October 2, 2014
    Applicants: Hoffmann-La Roche Inc., VIB vzw, Life Sciences Research Partners vzw
    Inventors: Sanne Lysbet de Haas, Paul Delmar, Diether Lambrechts, Stefan Scherer