Patents by Inventor Stefan Schunk

Stefan Schunk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230190946
    Abstract: Compounds of formula (1): and pharmaceutically acceptable salts and solvates thereof, are described. The compounds are ?4?7 antagonists and are useful in the prevention or treatment of inflammatory conditions and/or autoimmune diseases, especially inflammatory bowel disease.
    Type: Application
    Filed: December 20, 2022
    Publication date: June 22, 2023
    Inventor: Stefan Schunk
  • Publication number: 20210163491
    Abstract: The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
    Type: Application
    Filed: February 9, 2021
    Publication date: June 3, 2021
    Applicant: Grünenthal GmbH
    Inventors: Florian JAKOB, Jo ALEN, Simon LUCAS, Tobias CRAAN, Ingo KONETZKI, Achim KLESS, Stefan SCHUNK, Paul RATCLIFFE, Sebastian WACHTEN, Simon CRUWYS
  • Publication number: 20210139488
    Abstract: The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
    Type: Application
    Filed: January 20, 2021
    Publication date: May 13, 2021
    Applicant: GRÜNETHAL GMBH
    Inventors: Florian JAKOB, Jo ALEN, Simon LUCAS, Tobias CRAAN, Ingo KONETZKI, Achim KLESS, Stefan SCHUNK, Paul RATCLIFFE, Sebastian WACHTEN, Simon CRUWYS
  • Patent number: 10981918
    Abstract: The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: April 20, 2021
    Assignee: GRÜNENTHAL GMBH
    Inventors: Florian Jakob, Jo Alen, Simon Lucas, Tobias Craan, Ingo Konetzki, Achim Kless, Stefan Schunk, Paul Ratcliffe, Sebastian Wachten, Simon Cruwys
  • Publication number: 20200024281
    Abstract: The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
    Type: Application
    Filed: July 19, 2019
    Publication date: January 23, 2020
    Applicant: Grünenthal GmbH
    Inventors: Florian JAKOB, Jo ALEN, Simon LUCAS, Tobias CRAAN, Ingo KONETZKI, Achim KLESS, Stefan SCHUNK, Paul RATCLIFFE, Sebastian WACHTEN, Simon CRUWYS
  • Patent number: 10106530
    Abstract: The invention relates to pyrazolyl substituted tetrahydropyranylsulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: October 23, 2018
    Assignee: GRÜNENTHAL GMBH
    Inventors: Stefan Schunk, Melanie Reich, René Michael Koenigs
  • Patent number: 10100041
    Abstract: The invention relates to pyrazolyl substituted tetrahydropyranylsulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: October 16, 2018
    Assignee: GRÜNENTHAL GMBH
    Inventors: Stefan Schunk, Melanie Reich, René Michael Koenigs
  • Patent number: 9926302
    Abstract: The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: March 27, 2018
    Assignee: GRÜNENTHAL GMBH
    Inventors: Stefan Schunk, Melanie Reich, Florian Jakob, Nils Damann, Michael Haurand, Achim Kless, Marc Rogers, Kathy Mackenzie
  • Patent number: 9896440
    Abstract: The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: February 20, 2018
    Assignee: GRÜNENTHAL GMBH
    Inventors: Stefan Schunk, Melanie Reich, Florian Jakob, René Michael Koenigs, Nils Damann, Michael Haurand, Marc Rogers, Kathy MacKenzie, Richard Hamlyn
  • Patent number: 9879000
    Abstract: The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: January 30, 2018
    Assignee: GRÜNENTHAL GMBH
    Inventors: Stefan Schunk, Melanie Reich, Florian Jakob, Nils Damann, Michael Haurand, Achim Kless, Marc Rogers, Kathy MacKenzie
  • Publication number: 20170313703
    Abstract: Cis-tetrahydro-spiro(cyclohexane-1,1?-pyrido[3,4-b]indole)-4-amine compounds which act on the nociceptin/ORL-1 receptor system as well as on the ?-opioid receptor system and which are distinguished in particular by selective effectiveness in the treatment of chronic pain, such as inflammatory pain, visceral pain, tumour pain, and neuropathic pain, without at the same time developing pronounced effectiveness against acute, nociceptive pain.
    Type: Application
    Filed: July 19, 2017
    Publication date: November 2, 2017
    Inventors: Klaus LINZ, Saskia ZEMOLKA, Bert NOLTE, Stefan SCHUNK, Hans SCHICK
  • Patent number: 9802921
    Abstract: The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: October 31, 2017
    Assignee: GRUENENTHAL GMBH
    Inventors: Melanie Reich, Stefan Schunk, Florian Jakob, Henning Steinhagen, Nils Damann, Michael Haurand, Richard Hamlyn, Marc Rogers, Kathy MacKenzie
  • Publication number: 20170121314
    Abstract: The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: January 12, 2017
    Publication date: May 4, 2017
    Applicant: GRÜNENTHAL GMBH
    Inventors: STEFAN SCHUNK, Melanie Reich, Florian Jakob, Nils Damann, Michael Haurand, Achim Kless, Marc Rogers, Kathy Sutton
  • Publication number: 20170101397
    Abstract: The invention relates to pyrazolyl substituted tetrahydropyranylsulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: October 7, 2016
    Publication date: April 13, 2017
    Applicant: GRÜNENTHAL GMBH
    Inventors: Stefan Schunk, Melanie Reich, René Michael Koenigs
  • Publication number: 20170101398
    Abstract: The invention relates to pyrazolyl substituted tetrahydropyranylsulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: October 7, 2016
    Publication date: April 13, 2017
    Applicant: GRÜNENTHAL GMBH
    Inventors: Stefan SCHUNK, Melanie Reich, René Michael Koenigs
  • Patent number: 9562036
    Abstract: The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: February 7, 2017
    Assignee: GRÜNENTHAL GMBH
    Inventors: Melanie Reich, Stefan Schunk, Florian Jakob, Henning Steinhagen, Nils Damann, Michael Haurand, Marc Rogers, Kathy MacKenzie
  • Publication number: 20160297803
    Abstract: The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: June 14, 2016
    Publication date: October 13, 2016
    Inventors: Melanie REICH, Stefan SCHUNK, Florian JAKOB, Henning STEINHAGEN, Nils DAMANN, Michael HAURAND, Richard HAMLYN, Marc ROGERS, Kathy MACKENZIE
  • Publication number: 20160289186
    Abstract: The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: June 14, 2016
    Publication date: October 6, 2016
    Inventors: Melanie REICH, Stefan SCHUNK, Florian JAKOB, Nils DAMANN, Michael HAURAND, Richard HAMLYN, Marc ROGERS, Kathy MACKENZIE, Philip SKONE
  • Publication number: 20160289214
    Abstract: The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
    Type: Application
    Filed: June 17, 2016
    Publication date: October 6, 2016
    Applicant: GRÜNENTHAL GMBH
    Inventors: Melanie REICH, Stefan SCHUNK, Florian JAKOB, Henning STEINHAGEN, Nils DAMANN, Michael HAURAND, Marc ROGERS, Kathy MACKENZIE
  • Publication number: 20160159787
    Abstract: Cis-tetrahydro-spiro(cyclohexane-1,1?-pyrido[3,4-b]indole)-4-amine compounds which act on the nociceptin/ORL-1 receptor system as well as on the ?-opioid receptor system and which are distinguished in particular by selective effectiveness in the treatment of chronic pain, such as inflammatory pain, visceral pain, tumour pain, and neuropathic pain, without at the same time developing pronounced effectiveness against acute, nociceptive pain.
    Type: Application
    Filed: September 4, 2015
    Publication date: June 9, 2016
    Inventors: Klaus LINZ, Saskia ZEMOLKA, Bert NOLTE, Stefan SCHUNK, Hans SCHICK