Patents by Inventor Stefan Schunk

Stefan Schunk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted sulfonamide compounds
    Patent number: 8263598
    Abstract: Substituted sulfonamide compounds corresponding to the formula I wherein m, n, p, Q, R1, R2, R3, R4, X, Y and Z have the respective meanings defined herein, pharmaceutical compositions containing such compounds, a process for their preparation, and the use of such compounds for the treatment and/or inhibition of pain and other conditions mediated by bradykinin receptor 1 (B1R) and/or bradykinin receptor 2 (B2R).
    Type: Grant
    Filed: January 16, 2009
    Date of Patent: September 11, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Stefan Oberboersch, Ruth Jostock, Michael Engels, Stefan Schunk, Melanie Reich, Sabine Hees
  • Substituted benzimidazoles, benzothiazoles and benzoxazoles
    Patent number: 8232288
    Abstract: Substituted benzimidazoles, benzothiazoles and benzoxazoles, processes for their preparation, pharmaceutical compostions containing these compounds and the use of these compounds for treating or inhibiting disorders or disease states mediated at least in part by bradykinin receptor 1 (BR1).
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: July 31, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Jean De Vry, Ruth Jostock, Sabine Hees
  • Substituted sulfonamide compounds having bradykinin 1 receptor activity and use thereof as medicaments
    Patent number: 8178535
    Abstract: Substituted sulfonamide compounds corresponding to the formula I? wherein m, n, p, X, Y, Z, R1, RA and RB have specified meanings, processes for their preparation, pharmaceutical compositions containing these compounds, and the use of these substituted sulfonamide compounds for the treatment and/or inhibition of pain or other conditions.
    Type: Grant
    Filed: January 16, 2009
    Date of Patent: May 15, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Stefan Oberboersch, Ruth Jostock, Michael Engels, Stefan Schunk, Melanie Reich, Sabine Hees
  • Sulfonylated 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine compounds and their use as pharmaceuticals
    Patent number: 8158628
    Abstract: Sulfonylated tetrahydroazolopyrazine compounds corresponding to the formula I wherein R1, R2a, R2b, R3a, R3b, R4, R8, R9a, R9b, R10, R11, A, B, W1, W2 and W3 have the meanings defined herein, pharmaceutical compositions containing such compounds, a method for the preparation of such compounds, and the use of such compounds for treating or inhibiting various types of pain and/or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: April 17, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Stefan Oberboersch, Melanie Reich, Stefan Schunk, Ruth Jostock, Sabine Hees, Michael Engels, Tieno Germann, Edward Bijsterveld
  • Substituted Benzamide Compounds
    Publication number: 20120071461
    Abstract: Substituted benzamide compounds corresponding to formula (I) in which R5, R6, R7, R8, a, b, c, d, t, D and X have defined meanings, a process for their preparation, pharmaceutical compositions comprising such compounds, and a method of using such compounds to treat pain and other conditions mediated at least in part via the bradykinin 1 receptor.
    Type: Application
    Filed: September 22, 2011
    Publication date: March 22, 2012
    Applicant: GRUENENTHAL GmbH
    Inventors: Melanie Reich, Stefan Schunk, Ruth Jostock, Jean De Vry, Christa Kneip, Tieno Germann, Michael Engels
  • Substituted heteroaryl derivatives
    Patent number: 8138187
    Abstract: The invention relates to substituted heteroaryl derivatives, to methods for the production thereof, to medicaments containing said compounds and to the use of substituted heteroaryl derivatives for producing medicaments.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: March 20, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Saskia Zemolka, Stefan Schunk, Werner Englberger, Babette-Yvonne Kögel, Klaus Linz, Hans Schick, Helmut Sonnenschein, Heinz Graubaum, Claudia Hinze
  • Substituted Tetrahydropyrrolopyrazine Compounds
    Publication number: 20120058999
    Abstract: Tetrahydropyrrolopyrazine compounds, methods for their preparation, pharmaceutical compositions containing such compounds, and a method of using such compounds for the treatment of pain and other conditions mediated at least partially by Bradykinin 1 receptors (B1R).
    Type: Application
    Filed: September 2, 2011
    Publication date: March 8, 2012
    Applicant: Gruenenthal GmbH
    Inventors: Melanie REICH, Stefan SCHUNK, Stefan OBERBOERSCH, Ruth JOSTOCK, Tieno GERMANN, Michael ENGELS
  • Substituted sulfonamide compounds
    Patent number: 8124624
    Abstract: Substituted sulfonamide compounds corresponding to formula I: a process for their preparation, pharmaceutical compositions comprising such compounds, and the use of such substituted sulfonamide compounds in pharmaceutical compositions for the treatment of pain or other disorders or diseases that are mediated at least in part by B1R receptors.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: February 28, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Stefan Schunk, Michael Engels, Ruth Jostock, Tieno Germann, Sabine Hees
  • Substituted disulfonamide compounds
    Patent number: 8119805
    Abstract: Substituted disulfonamide compounds corresponding to formula I: In which R1, R2, R3, R4a, R4b, R5a, R5b, R8, R9a, R9b, R10, R11, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: February 21, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Melanie Reich, Stefan Schunk, Ruth Jostock, Sabine Hees, Tieno Germann, Michael Franz-Martin Engels
  • Cis-tetrahydro-spiro(cyclohexane-1,1'-pyrido[3,4-b]indole)-4-amine Compounds
    Publication number: 20120029006
    Abstract: Cis-tetrahydro-spiro(cyclohexane-1,1?-pyrido[3,4-b]indole)-4-amine compounds which act on the nociceptin/ORL-1 receptor system as well as on the ?-opioid receptor system and which are distinguished in particular by selective effectiveness in the treatment of chronic pain, such as inflammatory pain, visceral pain, tumour pain, and neuropathic pain, without at the same time developing pronounced effectiveness against acute, nociceptive pain.
    Type: Application
    Filed: July 28, 2011
    Publication date: February 2, 2012
    Applicant: Gruenenthal GmbH
    Inventors: Klaus Linz, Saskia Zemolka, Bert Nolte, Stefan Schunk, Hans Schick
  • Substituted amide compounds
    Patent number: 8106055
    Abstract: Substituted amide compounds corresponding to formula I: processes for preparing them, pharmaceutical compositions containing these compounds, and the use of substituted amide derivatives for the preparation of medicaments for the treatment of pain and various other conditions.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: January 31, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Utz-Peter Jagusch, Beatrix Merla, Stefan Schunk, Werner Englberger, Timo Struenker, Hagen-Heinrich Hennies, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • (Hetero)aryl cyclohexane derivatives
    Patent number: 7977370
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: July 12, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Saskia Zemolka, Stefan Schunk, Bert Nolte, Klaus Linz, Wolfgang Schröder, Werner Englberger, Hans Schick, Helmut Sonnenschein, Birgitta Henkel, József Bálint
  • Spirocyclic cyclohexane compounds
    Patent number: 7960404
    Abstract: Spirocyclic cyclohexane compounds corresponding to formula I in which R1 and R2 form a pyrrolidine ring or an azetidine ring and which exhibit increased metabolic stability, a process for producing such spirocyclic cyclohexane compounds, pharmaceutical compositions containing such spirocyclic cyclohexane compounds, and the use of such spirocyclic cyclohexane compounds to treat or inhibit pain and/or other disorders.
    Type: Grant
    Filed: August 21, 2009
    Date of Patent: June 14, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Schunk, Derek Saunders, Stephanie Harlfinger, Sonja Steufmehl
  • Substituted Benzimidazoles, Benzothiazoles and Benzoxazoles
    Publication number: 20110009382
    Abstract: Substituted benzimidazoles, benzothiazoles and benzoxazoles, processes for their preparation, pharmaceutical compostions containing these compounds and the use of these compounds for treating or inhibiting disorders or disease states mediated at least in part by bradykinin receptor 1 (BR1).
    Type: Application
    Filed: June 7, 2010
    Publication date: January 13, 2011
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Jean De Vry, Ruth Jostock, Sabine Hees
  • Substituted Sulfonamide Compounds
    Publication number: 20100324009
    Abstract: Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.
    Type: Application
    Filed: August 24, 2010
    Publication date: December 23, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan OBERBOERSCH, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Franz-Martin Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld
  • Substituted Sulfonamide Compounds
    Publication number: 20100317644
    Abstract: Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.
    Type: Application
    Filed: August 24, 2010
    Publication date: December 16, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan OBERBOERSCH, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Franz-Martin Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld
  • Substituted Spiro-amide Compounds
    Publication number: 20100249095
    Abstract: Substituted spiro-amide compounds corresponding to formula I in which R5 through R8, D, X, Y and Z have defined meanings, processes for preparing such spiro-amide compounds, pharmaceutical compositions containing such compounds, and methods of using such spiro-amide compounds for treating and/or inhibiting disorders or disease states mediated at least in part by the bradykinin 1 receptor.
    Type: Application
    Filed: March 24, 2010
    Publication date: September 30, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Stefan Oberboersch, Michael Engels, Tieno Germann, Ruth Jostock, Christa Kneip
  • Sulfonylated Tetrahydroazolopyrazines and their Use as Pharmaceuticals
    Publication number: 20100234387
    Abstract: Sulfonylated tetrahydroazolopyrazine compounds corresponding to the formula I wherein R1, R2a, R2b, R3a, R3b, R4, R8, R9a, R9b, R10, R11, A, B, W1, W2 and W3 have the meanings defined herein, pharmaceutical compositions containing such compounds, a method for the preparation of such compounds, and the use of such compounds for treating or inhibiting various types of pain and/or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).
    Type: Application
    Filed: March 4, 2010
    Publication date: September 16, 2010
    Applicant: Gruenethal GmbH
    Inventors: Beatrix MERLA, Stefan Oberboersch, Melanie Reich, Stefan Schunk, Ruth Jostock, Sabine Hees, Michael Engels, Tieno Germann, Edward Bijsterveld
  • Substituted Spiroamide Compounds
    Publication number: 20100234340
    Abstract: Substituted spiroamide compounds corresponding to formula (I): wherein A, B, Q1, Q2, Q3, Q4, R1, R8, R9a, R9b, R12, R13, R200 and R210 have defined meanings, processes for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).
    Type: Application
    Filed: February 5, 2010
    Publication date: September 16, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Ruth Jostock, Sabine Hees
  • Substituted Indole Compounds
    Publication number: 20100222324
    Abstract: Substituted indole compounds corresponding to the formula I: In which R8, R9a, R9b, R10, R11, R200, R210, A, D, T, q, s and t have defined meanings, processes for the preparation thereof, pharmaceutical compositions containing such compounds and the use of substituted indole compounds for the treatment or inhibition of pain and other conditions which are at least partly mediated by Bradykinin 1 receptors (B1R).
    Type: Application
    Filed: February 3, 2010
    Publication date: September 2, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Ruth Jostock, Sabine Hees