Patents by Inventor Stefan Sjolander
Stefan Sjolander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11499647Abstract: The invention relates to valve system for controlling a process fluid within a liquid processing system. The valve system comprises a valve arrangement, a pneumatic control system, and a connector unit. When the valve arrangement is connected to the connector unit, two or more valves are formed, such that the pneumatic control system controls an open/close or pressure control mode of the valves. A pump diaphragm system is disclosed, as well as a system for purifying a biological material that comprises the valve system or the pump diaphragm system. Also discloses are methods of using the valve system or the pump diaphragm system in a process for the purification of a biological material.Type: GrantFiled: December 9, 2019Date of Patent: November 15, 2022Assignee: Cytiva Sweden ABInventors: Klaus Heinrich Gebauer, Stefan Sjolander
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Publication number: 20220356959Abstract: The invention relates to valve system for controlling a process fluid within a liquid processing system. The valve system comprises a valve arrangement, a pneumatic control system, and a connector unit. When the valve arrangement is connected to the connector unit, two or more valves are formed, such that the pneumatic control system controls an open/close or pressure control mode of the valves. A pump diaphragm system is disclosed, as well as a system for purifying a biological material that comprises the valve system or the pump diaphragm system. Also discloses are methods of using the valve system or the pump diaphragm system in a process for the purification of a biological material.Type: ApplicationFiled: June 23, 2022Publication date: November 10, 2022Inventors: Klaus Heinrich Gebauer, Stefan Sjolander
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Patent number: 11179725Abstract: A self-adhesive layered septum is disclosed. In one example, the septum includes a first outer layer including a thermoplastic elastomer such as a styrenic block copolymer, containing styrene ethylene butylene styrene (TPE-SEBS) capable of closing at least partially an aperture formed when a needle is inserted through the layer; an adhesive second layer for adhering the septum to a mouth area of a well or container to which the septum is attachable; and a thermoplastic third layer between the first and second layers, thermobonded to the first layer and providing better adherence for the adhesive layer. The first layer includes a recess and a vent, which reduce pressure differentials in use, but together with the third layer minimize evaporation through the septum.Type: GrantFiled: July 6, 2017Date of Patent: November 23, 2021Assignee: CYTIVA SWEDEN ABInventors: Hakan Erik Roos, Stefan Sjolander, Per Kjellin, Bharath Subrahmanya
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Patent number: 10768108Abstract: A Surface Plasmon Resonance (SPR) biosensor system comprising: a SPR sensor surface, an illumination unit arranged to direct a wedge shaped beam of light at a line shaped detection area on the SPR sensor surface transverse to the direction of propagation of light, and a detection unit with detection optics for directing light reflected from the SPR sensor surface onto a two-dimensional optical detector unit such that the angle of reflection is imaged along one dimension and the width of the detection area along the other, wherein the illumination unit is arranged to selectively direct the wedge shaped beam of light at two or more spaced apart line shaped detection areas on the SPR sensor surface transverse to the direction of propagation of light.Type: GrantFiled: September 27, 2012Date of Patent: September 8, 2020Assignee: GE HEALTHCARE BIO-SCIENCES ABInventors: Bengt Ivarsson, Stefan Sjolander
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Publication number: 20200232576Abstract: The invention relates to valve system for controlling a process fluid within a liquid processing system. The valve system comprises a valve arrangement, a pneumatic control system, and a connector unit. When the valve arrangement is connected to the connector unit, two or more valves are formed, such that the pneumatic control system controls an open/close or pressure control mode of the valves. A pump diaphragm system is disclosed, as well as a system for purifying a biological material that comprises the valve system or the pump diaphragm system. Also discloses are methods of using the valve system or the pump diaphragm system in a process for the purification of a biological material.Type: ApplicationFiled: December 9, 2019Publication date: July 23, 2020Applicant: GE Healthcare Bio-Sciences ABInventors: Klaus Heinrich Gebauer, Stefan Sjolander
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Patent number: 10533680Abstract: The invention relates to valve system for controlling a process fluid within a liquid processing system. The valve system comprises a valve arrangement, a pneumatic control system, and a connector unit. When the valve arrangement is connected to the connector unit, two or more valves are formed, such that the pneumatic control system controls an open/close or pressure control mode of the valves. A pump diaphragm system is disclosed, as well as a system for purifying a biological material that comprises the valve system or the pump diaphragm system. Also discloses are methods of using the valve system or the pump diaphragm system in a process for the purification of a biological material.Type: GrantFiled: December 19, 2014Date of Patent: January 14, 2020Assignee: GE HEALTHCARE BIO-SCIENCES ABInventors: Klaus Heinrich Gebauer, Stefan Sjolander
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Patent number: 10451591Abstract: The invention relates to valve system for controlling a process fluid within a liquid processing system. The valve system comprises a valve arrangement, a pneumatic or hydraulic control system, and a connector unit. When the valve arrangement is connected to the connector unit, two or more valves are formed, such that the pneumatic or hydraulic control system controls an open/close or pressure control mode of the valves. A pump diaphragm system is disclosed, as well as a system for purifying a biological material that comprises the valve system or the pump diaphragm system. Also discloses are methods of using the valve system or the pump diaphragm system in a process for the purification of a biological material.Type: GrantFiled: June 21, 2016Date of Patent: October 22, 2019Assignee: GE HEALTHCARE BIO-SCIENCES ABInventors: Klaus Gebauer, Stefan Sjolander, Andreas Torbjorn Lundin
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Publication number: 20190308189Abstract: A self-adhesive layered septum is disclosed. In one example, the septum includes a first outer layer including a thermoplastic elastomer such as a styrenic block copolymer, containing styrene ethylene butylene styrene (TPE-SEBS) capable of closing at least partially an aperture formed when a needle is inserted through the layer; an adhesive second layer for adhering the septum to a mouth area of a well or container to which the septum is attachable; and a thermoplastic third layer between the first and second layers, thermobonded to the first layer and providing better adherence for the adhesive layer. The first layer includes a recess and a vent, which reduce pressure differentials in use, but together with the third layer minimize evaporation through the septum.Type: ApplicationFiled: July 6, 2017Publication date: October 10, 2019Inventors: Hakan Erik Roos, Stefan Sjolander, Per Kjellin, Bharath Subrahmanya
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Patent number: 9975123Abstract: The invention relates to a method for making a laminated microfluidics with membrane valves. The method comprises (a) generating a membrane valve assembly comprising (1) laminating three plastic foils together, the top foil comprising one through hole for each valve, the middle foil has a slit pattern connecting each valve hole of the top foil, and the bottom foil has one through hole for each valve and one additional hole entering the slit pattern; (2) placing the laminated foil, bottom foil down on a mould half having a smooth mould surface with one or more perpendicularly protruding cylinders that concentrically fit within the through holes of the laminated foil yet leave room for a membrane to form, and clamping a second mould half to close the mould; (3) injecting and allowing to cure a liquid rubber through a funnel associated with the bottom mould half and the additional hole on the bottom foil layer; and (b) laminating the membrane valve assembly and a flow path.Type: GrantFiled: November 28, 2014Date of Patent: May 22, 2018Assignee: GE HEALTHCARE BIO-SCIENCES ABInventor: Stefan Sjolander
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Patent number: 9958438Abstract: A flow cell unit to be docked against a flat lid surface to form a closed flow cell arrangement, the flow cell unit comprising a top surface with protruding walls of elastic material defining three or more adjacent elongated flow channels, each flow channel comprises a first fluid port and a second fluid port, wherein the walls separating adjacent flow channels comprises a valve section of reduced height, thereby allowing selective opening and closing of a flow path transverse to the elongated flow channels by controlling the docking force between flow cell and the lid surface to an open docking state and a closed docking state respectively.Type: GrantFiled: September 28, 2012Date of Patent: May 1, 2018Assignee: GE HEALTHCARE BIO-SCIENCES ABInventor: Stefan Sjolander
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Publication number: 20160319955Abstract: The invention relates to valve system for controlling a process fluid within a liquid processing system. The valve system comprises a valve arrangement, a pneumatic control system, and a connector unit. When the valve arrangement is connected to the connector unit, two or more valves are formed, such that the pneumatic control system controls an open/close or pressure control mode of the valves. A pump diaphragm system is disclosed, as well as a system for purifying a biological material that comprises the valve system or the pump diaphragm system. Also discloses are methods of using the valve system or the pump diaphragm system in a process for the purification of a biological material.Type: ApplicationFiled: December 19, 2014Publication date: November 3, 2016Inventors: Klaus Heinrich Gebauer, Stefan Sjolander
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Publication number: 20160310946Abstract: The invention relates to a method for making a laminated microfluidics with membrane valves. The method comprises (a) generating a membrane valve assembly comprising (1) laminating three plastic foils together, the top foil comprising one through hole for each valve, the middle foil has a slit pattern connecting each valve hole of the top foil, and the bottom foil has one through hole for each valve and one additional hole entering the slit pattern; (2) placing the laminated foil, bottom foil down on a mould half having a smooth mould surface with one or more perpendicularly protruding cylinders that concentrically fit within the through holes of the laminated foil yet leave room for a membrane to form, and clamping a second mould half to close the mould; (3) injecting and allowing to cure a liquid rubber through a funnel associated with the bottom mould half and the additional hole on the bottom foil layer; and (b) laminating the membrane valve assembly and a flow path.Type: ApplicationFiled: November 28, 2014Publication date: October 27, 2016Applicant: GE HEALTHCARE BIO-SCIENCES ABInventor: Stefan Sjolander
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Patent number: 9383335Abstract: Electrophoresis gel cassette comprising a first and a second face wall member and one or more side wall members defining a gel compartment for a gel member with a first and second face, wherein at least a section of each one of the first and second face wall member is removable to expose a section of both the first and second face of the gel member essentially corresponding to the separation zone while the gel member is preserved in the cassette.Type: GrantFiled: May 31, 2013Date of Patent: July 5, 2016Assignee: GE HEALTHCARE BIO-SCIENCES ABInventors: Lennart Bjorkesten, Owe Salven, Camilla Larsson, Erik J Bjerneld, Sofia Edlund, Henrik Ostlin, Stefan Sjolander, Kajsa Stridsberg-Friden, Ola Ronn, Peter Oliviusson, Henrik Bjorkman
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Patent number: 9377436Abstract: Electrophoresis gel cassette comprising a cassette housing defining a gel compartment for molding a gel member wherein the gel compartment comprises a fill port at an inlet end of the gel compartment and one or more over-fill ports at a distal end of the gel compartment with respect to a filling direction, and wherein the over-fill port(s) is arranged in fluidic communication with an overfill chamber.Type: GrantFiled: May 31, 2013Date of Patent: June 28, 2016Assignee: GE HEALTHCARE BIO-SCIENCES ABInventors: Owe Salven, Camilla Larsson, Stefan Ogeus, Henrik Ostlin, Stefan Sjolander, Malin Eriksson
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Patent number: 9360452Abstract: Electrophoresis tray arranged to support an electrophoresis cassette for miming electrophoresis experiments, the electrophoresis cassette comprising a gel member in a housing with a front and a back face, wherein the tray comprises a cassette support surface for supporting at least the separation zone of the electrophoresis cassette during electrophoresis, and wherein the cassette support surface is flanked by a pair of buffer pad holders each one arranged to hold a buffer pad in a mating position with respect to buffer connection sections at the back face of the electrophoresis cassette.Type: GrantFiled: May 31, 2013Date of Patent: June 7, 2016Assignee: GE HEALTHCARE BIO-SCIENCES ABInventors: Owe Salven, Camilla Larsson, Henrik Ostlin, Stefan Sjolander, Kajsa Stridsberg-Friden, Peter Oliviusson, Tomas Haukkala, Kjell Larsson, Anders Jahge
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Publication number: 20150219597Abstract: Electrophoresis system comprising at least one type of electrophoresis gel card, at least one type of blot membrane card, an electrophoresis apparatus for running electrophoresis experiments using the electrophoretic gel card, a blot transfer unit for transfer of separated sample from the electrophoresis gel card to the blot membrane card, an imaging apparatus for recording images of separated sample in the electrophoresis gel card and the blot membrane card, wherein; the electrophoresis gel card and the blot membrane card each comprises a rigid support provided with an alignment structure defining a positional reference for mutual alignment during transfer, and for alignment with respect to a complementary alignment structure in the imaging apparatus to provide mechanically aligned images of separated sample in the electrophoresis gel card and the blot membrane card.Type: ApplicationFiled: May 31, 2013Publication date: August 6, 2015Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: Camilla Larsson, Henrik Ostlin, Stefan Sjolander, Anders Jahge, Kajas Stridsberg-Friden
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Publication number: 20150192542Abstract: Method of manufacturing an electrophoresis gel cassette with a cassette housing defining a gel compartment for molding a gel member,comprising the steps of: molding in a rigid material a cassette housing member with an external face, an internal face defining at least a section of the gel compartment, and at least one opening for providing access to the gel compartment from the external face, and molding a closing member formed to close the at least one opening of the cassette housing member at the external face, wherein the closing member is molded with the cassette housing member acting partly as mold, and is comprised of an elastic material with non-permanent adhesion to the rigid material to make the closing member selectively removable.Type: ApplicationFiled: May 31, 2013Publication date: July 9, 2015Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: Camilla Larsson, Henrik Ostlin, Stefan Sjolander, Anders Jahge, Kajas Stridsberg-Friden
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Patent number: D733918Type: GrantFiled: May 13, 2014Date of Patent: July 7, 2015Assignee: GE Healthcare Bio-Sciences ABInventor: Stefan Sjolander
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Patent number: D733919Type: GrantFiled: May 13, 2014Date of Patent: July 7, 2015Assignee: GE Healthcare Bio-Sciences ABInventor: Stefan Sjolander
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Patent number: D733922Type: GrantFiled: May 13, 2014Date of Patent: July 7, 2015Assignee: GE Healthcare Bio-Sciences ABInventor: Stefan Sjolander