Abstract: A method of operating a multi-beam particle beam system includes: generating a multiplicity of particle beams such that they each pass through multipole elements that are either intact or defective; focusing the particle beams in a predetermined plane; determining excitations for the deflection elements of the multipole elements; exciting the deflection elements of the multipole elements that are intact with the determined excitations; modifying the determined excitations for the deflection elements of the multipole elements that are defective; and exciting the deflection elements of the defective multipole elements with the modified excitations. Modifying the determined excitations includes adding corrective excitations to the determined excitations. The corrective excitations are the same for all deflection elements of the defective multipole element.

Abstract: A sterile container unit for receiving items which are sterilized or are to be sterilized includes a container tray and a container lid that can be coupled to the container tray by a closure element. The closure element can be actuated by a pivoting movement. An information carrier can be interlockingly fastened to the container tray and set up to display information regarding the content of the sterile container unit. The container tray, the closure element and the information carrier are adapted to one another such that, following the pivoting movement of the closure element, the information carrier is rigidly fixed/locked on the container tray.

Abstract: A device for an anode gas recirculation in a fuel cell system includes a blower, an outer housing defining the blower, a condensate drain channel, a receiving element arranged at the outer housing, and a drain valve arranged in the receiving element. The blower incudes a rotor wheel, a delivery channel, an electric motor having a drive shaft to which the rotor wheel is attached, and a cooling channel through which an anode gas flows. The delivery channel extends from a delivery channel inlet to a delivery channel outlet. The cooling channel at least partially surrounds the electric motor of the blower. The condensate drain channel extends below the cooling channel in the outer housing. The cooling channel is fluidically connected to the condensate drain channel. The condensate drain channel is opened and closed by the drain valve so that a liquid can be drained from the condensate drain channel.

Abstract: A method for homogenizing glass includes the method: providing a cylindrical blank composed of the glass having a cylindrical outer surface that extends along a longitudinal axis of the blank between a first end face and a second end face, forming a shear zone in the blank by softening a longitudinal section of the blank and subjecting it to a thermal-mechanical intermixing treatment, and displacing the shear zone along the longitudinal axis of the blank. The displacement of the shear zone along the longitudinal axis of the blank is superimposed by a simultaneous oscillating motion of the shear zone along the longitudinal axis of the blank. The first end of the blank is rotated at a first rotational speed and the second end of the blank is rotated at a second rotational speed. An oscillating motion of the shear zone is generated by periodically varying the first and/or second rotational speed.

Abstract: Methods of producing bioconjugates of O-antigen polysaccharides covalently linked to a carrier protein using recombinant host cells are provided. The recombinant host cells used in the methods described herein encode a particular oligosaccharyl transferase enzyme depending on the O-antigen polysaccharide bioconjugate to be produced. The oligosaccharyl transferase enzymes can be PglB oligosaccharyl transferase or variants thereof. Also provided are compositions containing the bioconjugates, and methods of using the bioconjugates and compositions described herein to vaccinate a subject against extra-intestinal pathogenic E. coli. (ExPEC).

Abstract: A plug adapter connects to a solenoid valve already mounted in a motor vehicle. The plug adapter has a plug connector for receiving an electrical control signal from a control unit of the motor vehicle for operating the solenoid valve. The plug adapter includes a solenoid valve connector for detachable coupling of the plug adapter to the plug connector of the solenoid valve. The solenoid valve connector and the plug connector are matched to one another in terms of plug form and electrical signal transmission. An electronics component, such as a microcontroller, processes an electrical output signal for operating the solenoid valve when an electrical connection is established between the electronics component and the solenoid valve via the solenoid valve connector when the plug adapter is plugged into the plug connector.

Abstract: The present invention relates to fusion proteins targeted to the central nervous system (CNS) and its use for the treatment of lysosomal storage disorders (LSD).

Abstract: Systems and techniques are provided for a resource transfer system. An instruction to transfer a first quantity of a resource from a first resource pool to a second resource pool may be received. A hold may be placed on a second quantity of the resource in the first resource pool. The held second quantity of the first resource may not be transferred from the first resource pool until the hold is released. Responsive to receiving a message that fulfills a condition on the hold and an instruction to execute the transfer, the hold may be released. A register that is in the first resource pool and is associated with the resource may decremented by the first quantity, and a register that is in the second resource pool and is associated with the resource may be incremented by the first quantity.

Abstract: Systems and techniques are provided for a resource transfer system. An instruction to transfer a first quantity of a resource from a first resource pool to a second resource pool may be received. A hold may be placed on a second quantity of the resource in the first resource pool. The held second quantity of the first resource may not be transferred from the first resource pool until the hold is released. Responsive to receiving a message that fulfills a condition on the hold and an instruction to execute the transfer, the hold may be released. A register that is in the first resource pool and is associated with the resource may decremented by the first quantity, and a register that is in the second resource pool and is associated with the resource may be incremented by the first quantity.

Abstract: Systems and techniques are provided for a resource transfer system. An instruction to transfer a first quantity of a resource from a first resource pool to a second resource pool may be received. A hold may be placed on a second quantity of the resource in the first resource pool. The held second quantity of the first resource may not be transferred from the first resource pool until the hold is released. Responsive to receiving a message that fulfills a condition on the hold and an instruction to execute the transfer, the hold may be released. A register that is in the first resource pool and is associated with the resource may decremented by the first quantity, and a register that is in the second resource pool and is associated with the resource may be incremented by the first quantity.

Abstract: Systems and techniques are provided for electronic payment network security. Payment data including an origin and a destination for a payment in an electronic payment network may be received. A route of the payment in the electronic payment network may be estimated based on the origin and the destination. The estimated route of the payment in the electronic payment network may be input to a neural network. Fraud probabilities may be determined using the neural network. A fraud probability may include a value indicating a probability of fraud in the payment in the electronic payment network.

Abstract: A closing/locking mechanism for a sterile container includes an actuation lever, a tension bow or claw coupled to the actuation lever, and an engagement element forming an undercut and with which the tension bow or claw can be brought into operative engagement to apply a tensile force to the engagement element. The tension bow or claw is mounted for sliding transversely to the tensile force to be applied. A spring is arranged in an operative position relative to the tension bow or claw in such a way that, when a predefined actuation position of the actuation lever and a predefined/predefinable sliding position of the tension bow or claw are reached, in which position the tension bow or claw already reaches behind the engagement element, the spring applies a compressive force to the tension bow or claw in the direction of the tensile force.

Abstract: Systems and techniques are provided for a resource transfer system. An instruction to transfer a first quantity of a resource from a first resource pool to a second resource pool may be received. A hold may be placed on a second quantity of the resource in the first resource pool. The held second quantity of the first resource may not be transferred from the first resource pool until the hold is released. Responsive to receiving a message that fulfills a condition on the hold and an instruction to execute the transfer, the hold may be released. A register that is in the first resource pool and is associated with the resource may decremented by the first quantity, and a register that is in the second resource pool and is associated with the resource may be incremented by the first quantity.

Abstract: Systems and techniques are provided for a resource transfer system. An instruction to transfer a first quantity of a resource from a first resource pool to a second resource pool may be received. A hold may be placed on a second quantity of the resource in the first resource pool. The held second quantity of the first resource may not be transferred from the first resource pool until the hold is released. Responsive to receiving a message that fulfills a condition on the hold and an instruction to execute the transfer, the hold may be released. A register that is in the first resource pool and is associated with the resource may decremented by the first quantity, and a register that is in the second resource pool and is associated with the resource may be incremented by the first quantity.

Abstract: Systems and techniques are provided for a resource transfer system. An instruction to transfer a first quantity of a resource from a first resource pool to a second resource pool may be received. A hold may be placed on a second quantity of the resource in the first resource pool. The held second quantity of the first resource may not be transferred from the first resource pool until the hold is released. Responsive to receiving a message that fulfills a condition on the hold and an instruction to execute the transfer, the hold may be released. A register that is in the first resource pool and is associated with the resource may decremented by the first quantity, and a register that is in the second resource pool and is associated with the resource may be incremented by the first quantity.

Abstract: A closing/locking mechanism for a sterile container includes an actuation lever, a tension bow or claw coupled to the actuation lever, and an engagement element forming an undercut and with which the tension bow or claw can be brought into operative engagement to apply a tensile force to the engagement element. The tension bow or claw is mounted for sliding transversely to the tensile force to be applied. A spring is arranged in an operative position relative to the tension bow or claw in such a way that, when a predefined actuation position of the actuation lever and a predefined/predefinable sliding position of the tension bow or claw are reached, in which position the tension bow or claw already reaches behind the engagement element, the spring applies a compressive force to the tension bow or claw in the direction of the tensile force.

Abstract: Systems and techniques are provided for electronic payment network security. Payment data including an origin and a destination for a payment in an electronic payment network may be received. A route of the payment in the electronic payment network may be estimated based on the origin and the destination. The estimated route of the payment in the electronic payment network may be input to a neural network. Fraud probabilities may be determined using the neural network. A fraud probability may include a value indicating a probability of fraud in the payment in the electronic payment network.

Abstract: Systems and techniques are provided for a resource transfer system. An instruction to transfer a first quantity of a resource from a first resource pool to a second resource pool may be received. A hold may be placed on a second quantity of the resource in the first resource pool. The held second quantity of the first resource may not be transferred from the first resource pool until the hold is released. Responsive to receiving a message that fulfills a condition on the hold and an instruction to execute the transfer, the hold may be released. A register that is in the first resource pool and is associated with the resource may decremented by the first quantity, and a register that is in the second resource pool and is associated with the resource may be incremented by the first quantity.

Abstract: Systems and techniques are provided for a resource transfer system. An instruction to transfer a first quantity of a resource from a first resource pool to a second resource pool may be received. A hold may be placed on a second quantity of the resource in the first resource pool. The held second quantity of the first resource may not be transferred from the first resource pool until the hold is released. Responsive to receiving a message that fulfills a condition on the hold and an instruction to execute the transfer, the hold may be released. A register that is in the first resource pool and is associated with the resource may decremented by the first quantity, and a register that is in the second resource pool and is associated with the resource may be incremented by the first quantity.