Patents by Inventor Stephan Freyer

Stephan Freyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9109244
    Abstract: The invention relates to a process for the production of at least one microbial metabolite having at least 3 carbon atoms or at least 2 carbon atoms and at least 1 nitrogen atom by means of sugar-based microbial fermentation, comprising: a) the preparation of a sugar-containing liquid medium with a monosaccharide content of more than 20% by weight from a starch feedstock, the sugar-containing liquid medium also comprising non-starchy solid constituents of the starch feedstock; b) the fermentation of the sugar-containing liquid medium for the production of the metabolite(s); and c) depletion or isolation of at least one metabolite from the fermentation liquor, wherein a microorganism strain which produces the desired metabolite(s) is cultivated with the sugar-containing liquid medium, said liquid medium being obtained by: a1) milling the starch feedstock; and a2) liquefying the millbase in an aqueous liquid in the presence of at least one starch-liquefying enzyme, followed by saccharification using at least
    Type: Grant
    Filed: May 27, 2005
    Date of Patent: August 18, 2015
    Assignee: BASF SE
    Inventors: Markus Pompejus, Stephan Freyer, Markus Lohscheidt, Oskar Zelder, Matthias Boy
  • Patent number: 8852750
    Abstract: The present invention is directed to a method for coating a sheet-like cellulose containing material by applying a composition comprising at least one glucan (G), which has a ?(beta)-1,3-glycosidically linked main chain and at least one side group having a ?(beta)-1,6-glycosidic bond to the main chain, particularly Schizophyllan, and at least one solvent (S), particularly a ionic liquid, on the surface of the sheet-like material.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: October 7, 2014
    Assignees: Wintershall Holding GmbH, BASF SE
    Inventors: Mari Granström, Stephan Freyer, Rajan Hollmann, Julia Kristiane Schmidt, Alois Kindler
  • Patent number: 8785154
    Abstract: The present invention relates to a method for manufacturing an aqueous glucose solution from the starch components of Triticeae grains, for example from rye, triticale or in particular wheat grains. The invention also relates to a glucose-based fermentation method for manufacturing organic compounds in which the glucose manufactured for fermentation is produced from the starch components of Triticeae grains by way of a method according to the invention.
    Type: Grant
    Filed: April 9, 2009
    Date of Patent: July 22, 2014
    Assignee: BASF SE
    Inventors: Matthias Boy, Stephan Freyer, Julia Brodersen
  • Patent number: 8741599
    Abstract: A process for the fermentative production of at least one organic compound having at least 3 C atoms or having at least 2 C atoms and at least one 1 N atom, comprising the following steps: a1) milling a starch feedstock, thus obtaining a millbase which comprises at least part of the nonstarchy solid constituents of the starch feedstock; a2) suspending the millbase in an aqueous liquid and hydrolysis of the starch portion in the millbase by enzymatic liquefaction and, if appropriate, subsequent saccharification, whereby a first liquid (1) which comprises mono- or oligosaccharides is obtained; and b) addition of the liquid (1) which comprises mono- or oligosaccharides together with metabolizable mono-, di- or oligosaccharides or together with a composition which comprises metabolizable mono-, di- or oligosaccharide in a concentration of at least 50% by weight and which is essentially free from solids which are insoluble in water to a fermentation medium comprising a microorganism which is capable of overproduc
    Type: Grant
    Filed: November 27, 2006
    Date of Patent: June 3, 2014
    Assignee: BASF SE
    Inventors: Markus Pompejus, Stephan Freyer, Markus Lohscheidt, Oskar Zelder, Matthias Boy
  • Patent number: 8728773
    Abstract: Process for the production of at least one organic compound having at least 3 C atoms or having at least 2 C atoms and at least 1 N atom by fermentation. In particular, the process comprises milling a starch feedstock, thus obtaining a millbase which comprises at least part of the nonstarchy solid constituents of the starch feedstock; suspending the millbase in an aqueous liquid and liquefying the millbase present in the aqueous liquid in the presence of at least one starch-liquefying enzyme, obtaining an aqueous dextrin-containing medium (1) which comprises at least a part of the nonstarchy solid constituents of the starch feedstock; and using the aqueous dextrin-containing medium (1) in a fermentation for culturing a microorganism which is capable of overproducing the organic compound; wherein enzymes which hydrolyze the dextrins to monosaccharides are being added in an amount of less than 0.001% by weight based on the total weight of the starch feedstock employed, or not at all.
    Type: Grant
    Filed: November 27, 2006
    Date of Patent: May 20, 2014
    Inventors: Matthias Boy, Stephan Freyer
  • Patent number: 8728762
    Abstract: The invention relates to a method for producing at least one organic compound comprising at least 3 C-atoms or at least 2 C-atoms and at least 1 N-atom by fermentation. Said method comprises the following steps: i) a starch source is ground in order to obtain a grinding material which contains at least one part of the non-starch containing solid components of the starch source; ii) the grinding material is suspended in an aqueous liquid in an amount such that the dry mass content in the suspension is at least 45 wt.
    Type: Grant
    Filed: November 27, 2006
    Date of Patent: May 20, 2014
    Assignee: BASF SE
    Inventors: Matthias Boy, Stephan Freyer
  • Publication number: 20130310553
    Abstract: The present invention relates to novel methods for precipitating beta-glucan (?-glucan) by using high-molecular polyethylene glycol (PEG) and re-dissolving the precipitated ?-glucan in a suitable medium. The novel method of the present invention may also include drying the precipitated ?-glucan and/or swelling the precipitated b-glucan in a suitable solution before re-dissolving the ?-glucan.
    Type: Application
    Filed: May 14, 2013
    Publication date: November 21, 2013
    Applicant: Wintershall Holding GmbH
    Inventors: Tobias Käppler, Thorsten Haas, Julia Kristiane Schmidt, Christian Fleck, Stephan Freyer, Robert Bayer
  • Patent number: 8586794
    Abstract: The present invention relates to 5-isopropyl-3-aminomethyl-2-methyl-1-aminocyclohexane (carvonediamine) and to a process for preparation thereof by a) reacting carvone with hydrogen cyanide, b) then reacting the carvonenitrile obtained in stage a) with ammonia in the presence of an imine formation catalyst and c) then reacting the carvonenitrile imine-containing reaction mixture obtained in stage b) with hydrogen and ammonia over hydrogenation catalysts. The present invention further relates to the use of carvonediamine as a hardener for epoxy resins, as an intermediate in the preparation of diisocyanates, as a starter in the preparation of polyetherols and/or as a monomer for polyamide preparation.
    Type: Grant
    Filed: July 13, 2009
    Date of Patent: November 19, 2013
    Assignee: BASF SE
    Inventors: Martin Ernst, Alfred Oftring, Kathrin Wissel-Stoll, Oemer Uensal, Stephan Freyer, Ansgar Gereon Altenhoff, Wolfgang Staffel
  • Patent number: 8486669
    Abstract: A process for preparing glucose from a cellulose material, in which a cellulose-comprising starting material is provided and treated with a liquid treatment medium comprising an ionic liquid whose anions are selected from among polyatomic anions and the cellulose-comprising material which has been treated with the ionic liquid is subjected to an enzymatic hydrolysis, is described.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: July 16, 2013
    Assignee: BASF SE
    Inventors: Tim Balensiefer, Julia Brodersen, Giovanni D'Andola, Klemens Massonne, Stephan Freyer, Veit Stegmann
  • Publication number: 20120270033
    Abstract: The present invention is directed to a method for coating a sheet-like cellulose containing material by applying a composition comprising at least one glucan (G), which has a ?(beta)-1,3-glycosidically linked main chain and at least one side group having a ?(beta)-1,6-glycosidic bond to the main chain, particularly Schizophyllan, and at least one solvent (S), particularly a ionic liquid, on the surface of the sheet-like material.
    Type: Application
    Filed: March 28, 2012
    Publication date: October 25, 2012
    Applicants: Wintershall Holding GmbH, BASF SE
    Inventors: Mari Granström, Stephan Freyer, Rajan Hollmann, Julia Kristiane Schmidt, Alois Kindler
  • Publication number: 20120205099
    Abstract: A two-stage process for mineral oil production from mineral oil deposits with a deposit temperature of more than 70° C. and a salinity of 20 000 ppm to 350 000 ppm, in which an aqueous formulation comprising at least one glucan with a ?-1,3-glycosidically linked main chain, and side groups ?-1,6-glycosidcally bonded thereto and having a weight-average molecular weight Mw of 1.5*106 to 25*106 g/mol, are injected into a mineral oil deposit through at least one injection borehole and crude oil is withdrawn from the deposit through at least one production borehole. The aqueous formulation is prepared in two stages, by first preparing an aqueous concentrate of the glucan, and diluting the concentrate on site with water to the use concentration.
    Type: Application
    Filed: February 13, 2012
    Publication date: August 16, 2012
    Applicant: Wintershall Holding GmbH
    Inventors: Sebastian Briechle, Tillmann Faust, Stephan Freyer, Rajan Hollmann, Tobias Käppler, Bernd Leonhardt, Julia Kristiane Schmidt, Benjamin Wenzke, Foppe Visser
  • Publication number: 20120116068
    Abstract: The present invention describes a process for the degradation of cellulose by dissolving the cellulose in an ionic liquid and treating it with an acid, if appropriate with addition of water.
    Type: Application
    Filed: January 13, 2012
    Publication date: May 10, 2012
    Applicant: BASF SE
    Inventors: Veit STEGMANN, Stephan Freyer, Klemens Massonne, Giovanni D'Andola, Werner Mormann, Markus Wezstein, Wei Leng
  • Patent number: 8044166
    Abstract: The present invention relates to a process for preparing pentamethylene 1,5-diisocyanate, to pentamethylene 1,5-diisocyanate prepared in this way and to the use thereof.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: October 25, 2011
    Assignee: BASF Aktiengesellschaft
    Inventors: Martin Fiene, Eckhard Stroefer, Wolfgang Siegel, Stephan Freyer, Oskar Zelder, Gerhard Schulz
  • Publication number: 20110124918
    Abstract: The present invention relates to 5-isopropyl-3-aminomethyl-2-methyl-1-aminocyclohexane (carvonediamine) and to a process for preparation thereof by a) reacting carvone with hydrogen cyanide, b) then reacting the carvonenitrile obtained in stage a) with ammonia in the presence of an imine formation catalyst and c) then reacting the carvonenitrile imine-containing reaction mixture obtained in stage b) with hydrogen and ammonia over hydrogenation catalysts. The present invention further relates to the use of carvonediamine as a hardener for epoxy resins, as an intermediate in the preparation of diisocyanates, as a starter in the preparation of polyetherols and/or as a monomer for polyamide preparation.
    Type: Application
    Filed: July 13, 2009
    Publication date: May 26, 2011
    Applicant: BASF SE
    Inventors: Martin Ernst, Alfred Oftring, Kathrin Wissel-Stoll, Oemer Uensal, Stephan Freyer, Ansgar Gereon Altenhoff, Wolfgang Staffel
  • Publication number: 20110033896
    Abstract: The present invention relates to a method for manufacturing an aqueous glucose solution from the starch components of Triticeae grains, for example from rye, triticale or in particular wheat grains. The invention also relates to a glucose-based fermentation method for manufacturing organic compounds in which the glucose manufactured for fermentation is produced from the starch components of Triticeae grains by way of a method according to the invention.
    Type: Application
    Filed: April 9, 2009
    Publication date: February 10, 2011
    Applicant: BASF SE
    Inventors: Matthias Boy, Stephan Freyer, Julia Brodersen
  • Publication number: 20100112646
    Abstract: A process for preparing glucose from a cellulose material, in which a cellulose-comprising starting material is provided and treated with a liquid treatment medium comprising an ionic liquid whose anions are selected from among polyatomic anions and the cellulose-comprising material which has been treated with the ionic liquid is subjected to an enzymatic hydrolysis, is described.
    Type: Application
    Filed: January 22, 2008
    Publication date: May 6, 2010
    Applicant: BASF SE
    Inventors: Tim Balensiefer, Julia Brodersen, Giovanni D'Andola, Klemens Massonne, Stephan Freyer, Weit Stegmann
  • Publication number: 20100081798
    Abstract: The present invention relates to a process for preparing glucose from a lignocellulose-comprising starting material, in which this is firstly treated with an ionic liquid and subsequently subjected to an enzymatic hydrolysis. The invention further relates to a process for preparing microbial metabolites, especially ethanol, in which the glucose obtained is additionally subjected to a fermentation.
    Type: Application
    Filed: January 22, 2008
    Publication date: April 1, 2010
    Applicant: BASF SE
    Inventors: Tim Balensiefer, Hartwig Schroeder, Stephan Freyer, Giovanni D'Andola, Klemens Massonne
  • Publication number: 20090292100
    Abstract: The present invention relates to a process for preparing pentamethylene 1,5-diisocyanate, to pentamethylene 1,5-diisocyanate prepared in this way and to the use thereof.
    Type: Application
    Filed: July 25, 2007
    Publication date: November 26, 2009
    Applicant: BASF SE
    Inventors: Martin Fiene, Eckhard Stroefer, Wolfgang Siegel, Stephan Freyer, Oskar Zelder, Gerhard Schulz
  • Publication number: 20090226571
    Abstract: The present invention relates to a method for the production of at least one nonvolatile microbial metabolite in solid form by sugar-based microbial fermentation, in which process a microorganism strain which produces the desired metabolites is grown using a sugar-containing liquid medium with a monosaccharide content of more than 20% by weight based on the total weight of the liquid medium, and the volatile constituents of the fermentation liquor are subsequently largely removed, the sugar-containing liquid medium being prepared by: a1) milling selected starch feedstock from cereal grains; and a2) liquefying the millbase in an aqueous liquid in the presence of at least one starch-liquefying enzyme, followed by saccharification using at least one saccharifying enzyme, where, for liquefaction purposes, at least a portion of the millbase is liquefied by continuous or batchwise addition to the aqueous liquid.
    Type: Application
    Filed: September 6, 2006
    Publication date: September 10, 2009
    Applicant: BASF SE
    Inventors: Stephan Freyer, Markus Pompejus, Oskar Zelder, Markus Lohscheidt, Matthias Boy, Edzard Scholten
  • Publication number: 20090162892
    Abstract: The invention relates to a process for the production of at least one microbial metabolite having at least 3 carbon atoms or at least 2 carbon atoms and at least 1 nitrogen atom by means of sugar-based microbial fermentation, comprising: a) the preparation of a sugar-containing liquid medium with a monosaccharide content of more than 20% by weight from a starch feedstock, the sugar-containing liquid medium also comprising non-starchy solid constituents of the starch feedstock; b) the fermentation of the sugar-containing liquid medium for the production of the metabolite(s); and c) depletion or isolation of at least one metabolite from the fermentation liquor, wherein a microorganism strain which produces the desired metabolite(s) is cultivated with the sugar-containing liquid medium, said liquid medium being obtained by: a1) milling the starch feedstock; and a2) liquefying the millbase in an aqueous liquid in the presence of at least one starch-liquefying enzyme, followed by saccharification using at lea
    Type: Application
    Filed: May 27, 2005
    Publication date: June 25, 2009
    Applicant: BASF AG
    Inventors: Markus Pompejus, Stephan Freyer, Markus Lohscheidt, Oskar Zelder, Matthias Boy