Abstract: The invention relates to an adjustment device for adjusting shutoff elements of an air inlet of a motor compartment of a motor vehicle between at least a first position in which the air inlet is substantially closed and a second position in which the air inlet is substantially open. The adjustment device comprises a drive unit. The drive unit comprises a drive train, an electric motor with an output shaft for driving the drive train, and a drive shaft. The drive train comprises at least one reduction element. The reduction element, the output shaft of the electric motor, and the output shaft of the adjustment device form drive elements of the drive unit. The adjustment device is provided with a condition determining unit for determining a motion condition of at least one of the drive elements.

Abstract: An adjustment device for adjusting an air inlet of a motor compartment of a motor vehicle between at least a first position in which the air inlet is substantially open and a second position in which the air inlet is substantially closed, comprising a drive unit for adjusting the air inlet between at least the first position and the second position, further comprising an auxiliary unit which is arranged for adjusting the air inlet in case of a calamity for bringing the air inlet to a predefined position, comprising at least one energy storage element.

Abstract: A system for controlling thermal comfort in a space is provided with a variable mode of operation. The system may include a conditioner for conditioning air in the space, and a sensor for measuring a temperature in the space. A controller is provided for controlling the conditioner based on the temperature sensed by the sensor, and a fan for circulating air within the space is regulated based on the temperature sensed by the sensor. A related system for controlling a fan based on height is also provided, as is a system and method for easily and efficiently determining the height of a fan using a simple camera, such as one on a “smart” phone. A further aspect pertains to a controller, such as for example a portable handheld device, having a user interface adapted for suggesting an increase in a set point temperature of a thermostat based on the selected speed of the fan.

Abstract: Hair improvement compositions comprising covalent conjugates of a polypeptide and a hydrophilic polymer, or a polysaccharide and a hydrophilic polymer, or both, are provided herein. Methods for improving one or more physical characteristics of hair using the described compositions are also provided. The improvements can be semi-permanent.

Abstract: Hair improvement compositions comprising covalent conjugates of a polypeptide and a hydrophilic polymer, or a polysaccharide and a hydrophilic polymer, or both, are provided herein. Methods for improving one or more physical characteristics of hair using the described compositions are also provided. The improvements can be semi-permanent.

Abstract: An apparatus may receive bus data from a vehicle, may receive removable media storing an application and settings, and may interface with an external test hardware device. The apparatus may include a processor programmed to set up the test hardware device in accordance with the settings, and execute the application using the bus data and the external test hardware devices as configured. The apparatus may also update an indicator associated with a device category of a connected test hardware device to indicate presence of the test hardware device.

Abstract: The present invention relates to compounds and methods for the prevention or treatment of infections by negative strand RNA viruses, such as influenza virus and measles virus, wherein said compounds delay or inhibit viral replication by modulating the level or activity of a polypeptide involved in the synthesis or degradation of sphingosine-1-phosphate (S1P) in a cell, tissue, or subject. The methods involve administration of one or more compounds which modulate the level of gene expression, where the gene encodes a polypeptide involved in regulating the metabolic level of S1P, or modulate the level or activity of a polypeptide involved in regulating the metabolic level of S1P, such as sphingosine kinase (SK) and S1P lyase (SPL). Exemplary methods are directed towards reducing the level of SW by reducing the level or activity of one or more SKs, increasing the level or activity of one or more SPLs, or a combination of both steps.

Abstract: Provided herein are methods for improving skin quality in a subject comprising administering to the skin a pharmaceutical composition comprising a polypeptide covalently bound to a hydrophilic polymer and/or a polysaccharide covalently bound to a hydrophilic polymer.

Abstract: A portable rescue flotation device assembly for use in water rescues includes a floatation device having an elongated body portion and a handle assembly fixedly connected to the body portion. The body portion includes a durable water resistant skin configured to enclose a filler. The skin has an outside surface and an inside surface.

Abstract: A method is provided for mass spectrometry. The method includes generating precursor ions from a sample; transmitting the precursor ions into a collision cell; generating product ions in the collision cell; detecting the precursor and product ions; applying modulation to one or more of the precursor ion intensity and the product ion intensity; and identifying precursor ion and product ion relationships by analyzing intensity profiles defined by the modulation.

Abstract: According to features of the present disclosure, a gastric space filler device and methods effective for reducing stomach volume are disclosed. A gastric space filler comprising at least one inflatable space filler and a sleeve to prevent leakage out of the gastric space filler device is disclosed. The gastric space filler device may be inflated with an insufflation fluid and with mineral oil, which further has the effect of reducing leakage. Delivery systems and methods for inserting a gastric space filler device into a patient are also disclosed. Sheaths and methods for covering a gastric space filler device during delivery into a patient are also disclosed.

Abstract: Adjustment device for adjusting shutoff elements of an air inlet of a motor vehicle, wherein the shutoff elements are adjustable between an open position in which the air inlet is substantially open and a closed position in which the air inlet is substantially closed, includes a drive unit for adjusting the shutoff elements between at least the open position and the closed position, and a fail-safe mechanism which is arranged for adjusting the air inlet to a predefined position in case of a calamity situation. The adjustment device includes a blocking mechanism for blocking the operation of the fail-safe mechanism in predetermined situations, wherein in such predetermined situations the shutoff elements are adjustable to a predefined position without activation of the fail-safe mechanism.

Abstract: A document editor may manage suggested edits in a collaborative document. The document editor may instantiate a document model associated with the collaborative document. When a first editing suggestion is received for the collaborative document, a first suggestion command is associated with the first editing suggestion based on a type of the first editing suggestion and a type of the document model. The document editor may apply the first suggestion command on the document model to present the first editing suggestion within the collaborative document. When an acceptance indication for the first editing suggestion is received, the document model can be updated with the first suggestion command in response to the received acceptance indication.

Abstract: The invention relates to an adjustment device for adjusting shutoff strips of an at least partly closable air inlet of a motor compartment of a motor vehicle between at least a first position in which the shutoff strips leave the air inlet at least partly open and a second position in which the shutoff strips at least partly close the air inlet. The adjustment device comprises a drive unit, situated in a housing, which has a motor and a drive train with reduction stage. The drive train comprises an output shaft provided with a first coupling means facing outside the housing and a second coupling means facing outside the housing, opposite with respect to the first coupling means. The coupling means are configured to cooperate with, respectively, a first and a second coupling element of a first and second set of shutoff strips, respectively, for coupling the output shaft on both sides of the housing to the respective set of shutoff strips.

Abstract: A process for producing a compound of formula (I) is provided. The process comprises reacting a mixture comprising a compound of formula (IIA) and a compound of formula (IIB) with an alkyl alcohol in the presence of a Candida antarctica lipase B enzyme to produce a product comprising the compound of formula (I) and the compound of formula (IIB); wherein R1 is C1 to C6 alkyl; and wherein R2 is II or C1 to C12 alkyl. Also provided are processes for the production of R-lactic acid, oligomeric R-lactic acid, R,R-lactide, poly-R-lactic acid, alkyl S-lactate, S-lactic acid, oligomeric S-lactic acid, S,S-lactide, poly S-lactic acid and stereocomplex polylactic acid.

Abstract: Hair improvement compositions comprising covalent conjugates of a polypeptide and a hydrophilic polymer, or a polysaccharide and a hydrophilic polymer, or both, are provided herein. Methods for improving one or more physical characteristics of hair using the described compositions are also provided. The improvements can be semi-permanent.

Abstract: The invention relates to an adjustment device for adjusting shutoff elements of an air inlet of a motor compartment of a motor vehicle between at least a first position in which the air inlet is substantially closed and a second position in which the air inlet is substantially open. The adjustment device comprises a drive unit. The drive unit comprises a drive train, an electric motor with an output shaft for driving the drive train, and a drive shaft. The drive train comprises at least one reduction element. The reduction element, the output shaft of the electric motor, and the output shaft of the adjustment device form drive elements of the drive unit. The adjustment device is provided with a condition determining unit for determining a motion condition of at least one of the drive elements.

Abstract: A process for treating a mixture of R,R- and S,S-lactide is provided. The process involves contacting the lactide mixture with an aliphatic alcohol and/or an alkoxide to produce a mixture of R,R- and S,S-aliphatic ester of lactyllactic acid, subsequently contacting the mixture of R,R- and S,S-aliphatic ester of lactyllactic acid with an enzyme to produce a mixture comprising aliphatic ester of lactic acid corresponding to one lactide enantiomer and the aliphatic ester of lactyllactic acid corresponding to the other lactide enantiomer, and recovering the product. Also provided are processes for the production of S-lactic acid, S,S-lactide, poly-S-lactic acid, R-lactic acid, R,R-lactide, poly-R-lactic acid and stereocomplex polylactic acid.

Abstract: A process for treating a mixture of R,R- and S,S-lactide is provided. The process involves contacting the mixture with an aliphatic alcohol and an enzyme in the presence of a ketone solvent to produce a mixture comprising aliphatic ester of lactic acid corresponding to one lactide enantiomer, and the aliphatic ester of lactyllactic acid corresponding to the other lactide enantiomer. Also provided are processes for the production of S-lactic acid, S,S-lactide, poly-S-lactic acid, R-lactic acid, R,R-lactide, poly-R-lactic acid and stereocomplex polylactic acid.

Abstract: A process for treating a mixture of R,R- and S,S-lactide is provided. The process involves contacting the mixture with an aliphatic alcohol and an enzyme to produce a mixture comprising aliphatic ester of lactic acid corresponding to one lactide enantiomer and the aliphatic ester of lactyllactic acid corresponding to the other lactide enantiomer; separating the mixture from the enzyme, and recycling the enzyme to the process; and separating the aliphatic ester of lactic acid from the aliphatic ester of lactyl-lactic acid by fractional distillation. Also provided are processes for the production of S-lactic acid, S,S-lactide, poly-S-lactic acid, R-lactic acid, R,R-lactide, poly-R-lactic acid and stereocomplex polylactic acid.